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Items: 1 to 50 of 440

1.

The pathophysiological impact of stress on the dopamine system is dependent on the state of the critical period of vulnerability.

Gomes FV, Zhu X, Grace AA.

Mol Psychiatry. 2019 Sep 5. doi: 10.1038/s41380-019-0514-1. [Epub ahead of print]

PMID:
31488866
2.

Female rats are resistant to the long-lasting neurobehavioral changes induced by adolescent stress exposure.

Klinger K, Gomes FV, Rincón-Cortés M, Grace AA.

Eur Neuropsychopharmacol. 2019 Jul 29. pii: S0924-977X(19)30431-6. doi: 10.1016/j.euroneuro.2019.07.134. [Epub ahead of print]

PMID:
31371105
3.

Autonomic modulation of the electrical substrate in mice haploinsufficient for cardiac sodium channels: a model of the Brugada syndrome.

Finlay M, Bhar-Amato J, Ng KE, Santos D, Orini M, Vyas V, Taggart P, Grace AA, Huang CL, Lambiase PD, Tinker A.

Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C576-C583. doi: 10.1152/ajpcell.00028.2019. Epub 2019 Jul 10.

PMID:
31291141
4.

The medial septum enhances reversal learning via opposing actions on ventral tegmental area and substantia nigra dopamine neurons.

Bortz DM, Gazo KL, Grace AA.

Neuropsychopharmacology. 2019 Jul 1. doi: 10.1038/s41386-019-0453-1. [Epub ahead of print]

PMID:
31261368
5.

Insights on current and novel antipsychotic mechanisms from the MAM model of schizophrenia.

Sonnenschein SF, Grace AA.

Neuropharmacology. 2019 May 8. pii: S0028-3908(19)30159-5. doi: 10.1016/j.neuropharm.2019.05.009. [Epub ahead of print] Review.

PMID:
31077730
6.

Ageing in Pgc-1β-/- mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology.

Edling CE, Fazmin IT, Chadda KR, Ahmad S, Valli H, Grace AA, Huang CL, Jeevaratnam K.

Biosci Rep. 2019 Apr 17;39(4). pii: BSR20190127. doi: 10.1042/BSR20190127. Print 2019 Apr 30.

7.

Nicotine self-administration is not increased in the MAM rodent model of schizophrenia.

Weeks JJ, Rupprecht LE, Grace AA, Donny EC, Sved AF.

Nicotine Tob Res. 2019 Mar 22. pii: ntz048. doi: 10.1093/ntr/ntz048. [Epub ahead of print]

PMID:
30899959
8.

Quinidine Rebooted: Contemporary Approaches to Multichannel Blockade.

Grace AA, Matthews GDK.

JACC Clin Electrophysiol. 2019 Mar;5(3):383-386. doi: 10.1016/j.jacep.2019.01.015. No abstract available.

PMID:
30898242
9.

Stress during critical periods of development and risk for schizophrenia.

Gomes FV, Zhu X, Grace AA.

Schizophr Res. 2019 Jan 30. pii: S0920-9964(19)30020-9. doi: 10.1016/j.schres.2019.01.030. [Epub ahead of print]

PMID:
30711313
10.

Towards a Unifying Cognitive, Neurophysiological, and Computational Neuroscience Account of Schizophrenia.

Heinz A, Murray GK, Schlagenhauf F, Sterzer P, Grace AA, Waltz JA.

Schizophr Bull. 2019 Sep 11;45(5):1092-1100. doi: 10.1093/schbul/sby154.

PMID:
30388260
11.

Pharmacological Modulation of Right Ventricular Endocardial-Epicardial Gradients in Brugada Syndrome.

Bhar-Amato J, Finlay M, Santos D, Orini M, Chaubey S, Vyas V, Taggart P, Grace AA, Huang CL, Ben Simon R, Tinker A, Lambiase PD.

Circ Arrhythm Electrophysiol. 2018 Sep;11(9):e006330. doi: 10.1161/CIRCEP.118.006330.

PMID:
30354290
12.

Correction: Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis.

Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, McGuire P.

Neuropsychopharmacology. 2018 Dec;43(13):2660. doi: 10.1038/s41386-018-0118-5.

13.

State-dependent effects of the D2 partial agonist aripiprazole on dopamine neuron activity in the MAM neurodevelopmental model of schizophrenia.

Sonnenschein SF, Gill KM, Grace AA.

Neuropsychopharmacology. 2019 Feb;44(3):572-580. doi: 10.1038/s41386-018-0219-1. Epub 2018 Sep 18.

PMID:
30267014
14.
15.

Correction: Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis.

Winton-Brown T, Schmidt A, Roiser JP, Howes OD, Egerton A, Fusar-Poli P, Bunzeck N, Grace AA, Duzel E, Kapur S, McGuire P.

Transl Psychiatry. 2018 Aug 31;8(1):170. doi: 10.1038/s41398-018-0189-4.

16.

Prefrontal cortex modulates firing pattern in the nucleus reuniens of the midline thalamus via distinct corticothalamic pathways.

Zimmerman EC, Grace AA.

Eur J Neurosci. 2018 Nov;48(10):3255-3272. doi: 10.1111/ejn.14111. Epub 2018 Sep 24.

PMID:
30107061
17.

Cortical dopamine dysregulation in schizophrenia and its link to stress.

Gomes FV, Grace AA.

Brain. 2018 Jul 1;141(7):1897-1899. doi: 10.1093/brain/awy156. No abstract available.

18.

Ablation of Complex Fractionated Electrograms Improves Outcome in Persistent Atrial Fibrillation of Over 2 Year's Duration.

Martin CA, Curtain JP, Gajendragadkar PR, Begley DA, Fynn SP, Grace AA, Heck PM, Virdee MS, Agarwal S.

J Atr Fibrillation. 2018 Feb 28;10(5):1607. doi: 10.4022/jafib.1607. eCollection 2018 Feb.

19.

Fear extinction disruption in a developmental rodent model of schizophrenia correlates with an impairment in basolateral amygdala-medial prefrontal cortex plasticity.

Uliana DL, Resstel LBM, Grace AA.

Neuropsychopharmacology. 2018 Nov;43(12):2459-2467. doi: 10.1038/s41386-018-0128-3. Epub 2018 Jun 23.

PMID:
29973655
20.

Diazepam reverses increased anxiety-like behavior, social behavior deficit, and dopamine dysregulation following withdrawal from acute amphetamine.

Rincón-Cortés M, Gagnon KG, Dollish HK, Grace AA.

Neuropsychopharmacology. 2018 Nov;43(12):2418-2425. doi: 10.1038/s41386-018-0123-8. Epub 2018 Jun 18.

PMID:
29959439
21.

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kääb S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A.

EMBO J. 2018 Jun 15;37(12). pii: e98133. doi: 10.15252/embj.201798133. Epub 2018 May 15.

22.

Altered brain cannabinoid 1 receptor mRNA expression across postnatal development in the MAM model of schizophrenia.

Gomes FV, Edelson JR, Volk DW, Grace AA.

Schizophr Res. 2018 Nov;201:254-260. doi: 10.1016/j.schres.2018.04.030. Epub 2018 Apr 26.

PMID:
29705007
23.

α7 Nicotinic receptor-modulating agents reverse the hyperdopaminergic tone in the MAM model of schizophrenia.

Neves GA, Grace AA.

Neuropsychopharmacology. 2018 Jul;43(8):1712-1720. doi: 10.1038/s41386-018-0066-0. Epub 2018 Apr 19.

24.

Medial septum differentially regulates dopamine neuron activity in the rat ventral tegmental area and substantia nigra via distinct pathways.

Bortz DM, Grace AA.

Neuropsychopharmacology. 2018 Sep;43(10):2093-2100. doi: 10.1038/s41386-018-0048-2. Epub 2018 Mar 27.

25.

Phenotypic Landscape and Risk Management in Long QT Syndrome: Nudging Forward.

Grace AA, Matthews GDK.

J Am Coll Cardiol. 2018 Apr 17;71(15):1672-1675. doi: 10.1016/j.jacc.2018.02.040. No abstract available.

26.

Continuous and minimally-interrupted direct oral anticoagulant are both safe compared with vitamin K antagonist for atrial fibrillation ablation: An updated meta-analysis.

Ha FJ, Barra S, Brown AJ, Begley DA, Grace AA, Agarwal S.

Int J Cardiol. 2018 Jul 1;262:51-56. doi: 10.1016/j.ijcard.2018.03.095. Epub 2018 Mar 21. Review.

PMID:
29606512
27.

Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis.

Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, McGuire P.

Neuropsychopharmacology. 2018 Dec;43(13):2652-2659. doi: 10.1038/s41386-017-0004-6. Epub 2018 Jan 30. Erratum in: Neuropsychopharmacology. 2018 Oct 2;:.

28.

The Circuitry of Dopamine System Regulation and its Disruption in Schizophrenia: Insights Into Treatment and Prevention.

Grace AA, Gomes FV.

Schizophr Bull. 2019 Jan 1;45(1):148-157. doi: 10.1093/schbul/sbx199. Review.

PMID:
29385549
29.

Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB.

Hasbi A, Perreault ML, Shen MYF, Fan T, Nguyen T, Alijaniaram M, Banasikowski TJ, Grace AA, O'Dowd BF, Fletcher PJ, George SR.

Front Pharmacol. 2018 Jan 4;8:924. doi: 10.3389/fphar.2017.00924. eCollection 2017.

30.

Increased Resting Hippocampal and Basal Ganglia Perfusion in People at Ultra High Risk for Psychosis: Replication in a Second Cohort.

Allen P, Azis M, Modinos G, Bossong MG, Bonoldi I, Samson C, Quinn B, Kempton MJ, Howes OD, Stone JM, Calem M, Perez J, Bhattacharayya S, Broome MR, Grace AA, Zelaya F, McGuire P.

Schizophr Bull. 2018 Oct 17;44(6):1323-1331. doi: 10.1093/schbul/sbx169.

PMID:
29294102
31.

Inhibitory Modulation of Orbitofrontal Cortex on Medial Prefrontal Cortex-Amygdala Information Flow.

Chang CH, Grace AA.

Cereb Cortex. 2018 Jan 1;28(1):1-8. doi: 10.1093/cercor/bhw342.

32.

Divergent effects of acute and repeated quetiapine treatment on dopamine neuron activity in normal vs. chronic mild stress induced hypodopaminergic states.

Moreines JL, Owrutsky ZL, Gagnon KG, Grace AA.

Transl Psychiatry. 2017 Dec 11;7(12):1275. doi: 10.1038/s41398-017-0039-9. Review.

33.

Dopamine System Dysregulation in Major Depressive Disorders.

Belujon P, Grace AA.

Int J Neuropsychopharmacol. 2017 Dec 1;20(12):1036-1046. doi: 10.1093/ijnp/pyx056. Review.

34.

Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research?

Scharfman HE, Kanner AM, Friedman A, Blümcke I, Crocker CE, Cendes F, Diaz-Arrastia R, Förstl H, Fenton AA, Grace AA, Palop J, Morrison J, Nehlig A, Prasad A, Wilcox KS, Jette N, Pohlmann-Eden B.

Epilepsy Behav. 2018 Jan;78:302-312. doi: 10.1016/j.yebeh.2017.09.016. Epub 2017 Oct 31. Review.

35.

Epac-induced ryanodine receptor type 2 activation inhibits sodium currents in atrial and ventricular murine cardiomyocytes.

Valli H, Ahmad S, Sriharan S, Dean LD, Grace AA, Jeevaratnam K, Matthews HR, Huang CL.

Clin Exp Pharmacol Physiol. 2018 Mar;45(3):278-292. doi: 10.1111/1440-1681.12870. Epub 2017 Dec 7.

36.

Cortical GABA in Subjects at Ultra-High Risk of Psychosis: Relationship to Negative Prodromal Symptoms.

Modinos G, Simsek F, Horder J, Bossong M, Bonoldi I, Azis M, Perez J, Broome M, Lythgoe DJ, Stone JM, Howes OD, Murphy DG, Grace AA, Allen P, McGuire P.

Int J Neuropsychopharmacol. 2018 Feb 1;21(2):114-119. doi: 10.1093/ijnp/pyx076.

37.

Psychogenic Stress Activates C-Fos in Nucleus Accumbens-Projecting Neurons of the Hippocampal Ventral Subiculum.

Lipski WJ, Dibble SM, Rinaman L, Grace AA.

Int J Neuropsychopharmacol. 2017 Oct 1;20(10):855-860. doi: 10.1093/ijnp/pyx054.

38.

Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis.

Winton-Brown T, Schmidt A, Roiser JP, Howes OD, Egerton A, Fusar-Poli P, Bunzeck N, Grace AA, Duzel E, Kapur S, McGuire P.

Transl Psychiatry. 2017 Oct 3;7(10):e1245. doi: 10.1038/tp.2017.174. Erratum in: Transl Psychiatry. 2018 Aug 31;8(1):170.

39.

Age-dependent electrocardiographic changes in Pgc-1β deficient murine hearts.

Ahmad S, Valli H, Salvage SC, Grace AA, Jeevaratnam K, Huang CL.

Clin Exp Pharmacol Physiol. 2018 Feb;45(2):174-186. doi: 10.1111/1440-1681.12863. Epub 2017 Nov 29.

40.

Impaired contextual fear-conditioning in MAM rodent model of schizophrenia.

Gill KM, Miller SA, Grace AA.

Schizophr Res. 2018 May;195:343-352. doi: 10.1016/j.schres.2017.08.064. Epub 2017 Sep 18.

41.

Age-dependent atrial arrhythmic phenotype secondary to mitochondrial dysfunction in Pgc-1β deficient murine hearts.

Valli H, Ahmad S, Chadda KR, Al-Hadithi ABAK, Grace AA, Jeevaratnam K, Huang CL.

Mech Ageing Dev. 2017 Oct;167:30-45. doi: 10.1016/j.mad.2017.09.002. Epub 2017 Sep 14.

42.

The effects of ageing and adrenergic challenge on electrocardiographic phenotypes in a murine model of long QT syndrome type 3.

Chadda KR, Ahmad S, Valli H, den Uijl I, Al-Hadithi AB, Salvage SC, Grace AA, Huang CL, Jeevaratnam K.

Sci Rep. 2017 Sep 11;7(1):11070. doi: 10.1038/s41598-017-11210-3.

44.

Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β -/- hearts.

Ahmad S, Valli H, Edling CE, Grace AA, Jeevaratnam K, Huang CL.

Pflugers Arch. 2017 Dec;469(12):1579-1590. doi: 10.1007/s00424-017-2054-3. Epub 2017 Aug 18.

45.

The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction.

Perreault ML, Fan T, Banasikowski TJ, Grace AA, George SR.

Eur J Neurosci. 2017 Aug;46(4):2015-2025. doi: 10.1111/ejn.13635. Epub 2017 Aug 1.

PMID:
28677227
46.

Sex-Dependent Effects of Stress on Immobility Behavior and VTA Dopamine Neuron Activity: Modulation by Ketamine.

Rincón-Cortés M, Grace AA.

Int J Neuropsychopharmacol. 2017 Oct 1;20(10):823-832. doi: 10.1093/ijnp/pyx048.

47.

Improved outcome and cost effectiveness in ablation of persistent atrial fibrillation under general anaesthetic.

Martin CA, Curtain JP, Gajendragadkar PR, Begley DA, Fynn SP, Grace AA, Heck PM, Salaunkey K, Virdee MS, Agarwal S.

Europace. 2018 Jun 1;20(6):935-942. doi: 10.1093/europace/eux057.

PMID:
28444228
48.

Adolescent Stress as a Driving Factor for Schizophrenia Development-A Basic Science Perspective.

Gomes FV, Grace AA.

Schizophr Bull. 2017 May 1;43(3):486-489. doi: 10.1093/schbul/sbx033. Review.

49.

Transforming growth factor β receptor inhibition prevents ventricular fibrosis in a mouse model of progressive cardiac conduction disease.

Derangeon M, Montnach J, Cerpa CO, Jagu B, Patin J, Toumaniantz G, Girardeau A, Huang CLH, Colledge WH, Grace AA, Baró I, Charpentier F.

Cardiovasc Res. 2017 Apr 1;113(5):464-474. doi: 10.1093/cvr/cvx026.

PMID:
28339646
50.

Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia.

Steullet P, Cabungcal JH, Coyle J, Didriksen M, Gill K, Grace AA, Hensch TK, LaMantia AS, Lindemann L, Maynard TM, Meyer U, Morishita H, O'Donnell P, Puhl M, Cuenod M, Do KQ.

Mol Psychiatry. 2017 Jul;22(7):936-943. doi: 10.1038/mp.2017.47. Epub 2017 Mar 21.

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