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Items: 1 to 50 of 446

1.

Neural Circuitry of Novelty Salience Processing in Psychosis Risk: Association With Clinical Outcome.

Modinos G, Allen P, Zugman A, Dima D, Azis M, Samson C, Bonoldi I, Quinn B, Gifford GWG, Smart SE, Antoniades M, Bossong MG, Broome MR, Perez J, Howes OD, Stone JM, Grace AA, McGuire P.

Schizophr Bull. 2019 Sep 18. pii: sbz089. doi: 10.1093/schbul/sbz089. [Epub ahead of print]

PMID:
32227226
2.

Noninvasive ultrasound deep brain stimulation of nucleus accumbens induces behavioral avoidance.

Niu L, Guo Y, Lin Z, Shi Z, Bian T, Qi L, Meng L, Grace AA, Zheng H, Yuan TF.

Sci China Life Sci. 2020 Mar 13. doi: 10.1007/s11427-019-1616-6. [Epub ahead of print]

PMID:
32180109
3.

Antidepressant effects of ketamine on depression-related phenotypes and dopamine dysfunction in rodent models of stress.

Rincón-Cortés M, Grace AA.

Behav Brain Res. 2020 Feb 3;379:112367. doi: 10.1016/j.bbr.2019.112367. Epub 2019 Nov 15. Review.

PMID:
31739001
4.

Postpartum changes in affect-related behavior and VTA dopamine neuron activity in rats.

Rincón-Cortés M, Grace AA.

Prog Neuropsychopharmacol Biol Psychiatry. 2020 Mar 8;97:109768. doi: 10.1016/j.pnpbp.2019.109768. Epub 2019 Oct 23.

PMID:
31655159
5.

α7 nicotinic receptor full agonist reverse basolateral amygdala hyperactivity and attenuation of dopaminergic neuron activity in rats exposed to chronic mild stress.

Neves GA, Grace AA.

Eur Neuropsychopharmacol. 2019 Dec;29(12):1343-1353. doi: 10.1016/j.euroneuro.2019.09.009. Epub 2019 Oct 12.

PMID:
31615702
6.

Correction: The pathophysiological impact of stress on the dopamine system is dependent on the state of the critical period of vulnerability.

Gomes FV, Zhu X, Grace AA.

Mol Psychiatry. 2019 Sep 27. doi: 10.1038/s41380-019-0527-9. [Epub ahead of print]

PMID:
31562399
7.

The pathophysiological impact of stress on the dopamine system is dependent on the state of the critical period of vulnerability.

Gomes FV, Zhu X, Grace AA.

Mol Psychiatry. 2019 Sep 5. doi: 10.1038/s41380-019-0514-1. [Epub ahead of print] Erratum in: Mol Psychiatry. 2019 Sep 27;:.

PMID:
31488866
8.

Female rats are resistant to the long-lasting neurobehavioral changes induced by adolescent stress exposure.

Klinger K, Gomes FV, Rincón-Cortés M, Grace AA.

Eur Neuropsychopharmacol. 2019 Oct;29(10):1127-1137. doi: 10.1016/j.euroneuro.2019.07.134. Epub 2019 Jul 29.

PMID:
31371105
9.

Autonomic modulation of the electrical substrate in mice haploinsufficient for cardiac sodium channels: a model of the Brugada syndrome.

Finlay M, Bhar-Amato J, Ng KE, Santos D, Orini M, Vyas V, Taggart P, Grace AA, Huang CL, Lambiase PD, Tinker A.

Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C576-C583. doi: 10.1152/ajpcell.00028.2019. Epub 2019 Jul 10.

PMID:
31291141
10.

The medial septum enhances reversal learning via opposing actions on ventral tegmental area and substantia nigra dopamine neurons.

Bortz DM, Gazo KL, Grace AA.

Neuropsychopharmacology. 2019 Dec;44(13):2186-2194. doi: 10.1038/s41386-019-0453-1. Epub 2019 Jul 1.

PMID:
31261368
11.

Insights on current and novel antipsychotic mechanisms from the MAM model of schizophrenia.

Sonnenschein SF, Grace AA.

Neuropharmacology. 2020 Feb;163:107632. doi: 10.1016/j.neuropharm.2019.05.009. Epub 2019 May 8. Review.

PMID:
31077730
12.

Ageing in Pgc-1β-/- mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology.

Edling CE, Fazmin IT, Chadda KR, Ahmad S, Valli H, Grace AA, Huang CL, Jeevaratnam K.

Biosci Rep. 2019 Apr 17;39(4). pii: BSR20190127. doi: 10.1042/BSR20190127. Print 2019 Apr 30.

13.

Nicotine Self-administration Is Not Increased in the Methylazoxymethanol Acetate Rodent Model of Schizophrenia.

Weeks JJ, Rupprecht LE, Grace AA, Donny EC, Sved AF.

Nicotine Tob Res. 2020 Feb 6;22(2):204-212. doi: 10.1093/ntr/ntz048.

PMID:
30899959
14.

Quinidine Rebooted: Contemporary Approaches to Multichannel Blockade.

Grace AA, Matthews GDK.

JACC Clin Electrophysiol. 2019 Mar;5(3):383-386. doi: 10.1016/j.jacep.2019.01.015. No abstract available.

15.

Stress during critical periods of development and risk for schizophrenia.

Gomes FV, Zhu X, Grace AA.

Schizophr Res. 2019 Nov;213:107-113. doi: 10.1016/j.schres.2019.01.030. Epub 2019 Jan 30.

PMID:
30711313
16.

Towards a Unifying Cognitive, Neurophysiological, and Computational Neuroscience Account of Schizophrenia.

Heinz A, Murray GK, Schlagenhauf F, Sterzer P, Grace AA, Waltz JA.

Schizophr Bull. 2019 Sep 11;45(5):1092-1100. doi: 10.1093/schbul/sby154.

PMID:
30388260
17.

Pharmacological Modulation of Right Ventricular Endocardial-Epicardial Gradients in Brugada Syndrome.

Bhar-Amato J, Finlay M, Santos D, Orini M, Chaubey S, Vyas V, Taggart P, Grace AA, Huang CL, Ben Simon R, Tinker A, Lambiase PD.

Circ Arrhythm Electrophysiol. 2018 Sep;11(9):e006330. doi: 10.1161/CIRCEP.118.006330.

PMID:
30354290
18.

Correction: Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis.

Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, McGuire P.

Neuropsychopharmacology. 2018 Dec;43(13):2660. doi: 10.1038/s41386-018-0118-5.

19.

State-dependent effects of the D2 partial agonist aripiprazole on dopamine neuron activity in the MAM neurodevelopmental model of schizophrenia.

Sonnenschein SF, Gill KM, Grace AA.

Neuropsychopharmacology. 2019 Feb;44(3):572-580. doi: 10.1038/s41386-018-0219-1. Epub 2018 Sep 18.

20.
21.

Correction: Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis.

Winton-Brown T, Schmidt A, Roiser JP, Howes OD, Egerton A, Fusar-Poli P, Bunzeck N, Grace AA, Duzel E, Kapur S, McGuire P.

Transl Psychiatry. 2018 Aug 31;8(1):170. doi: 10.1038/s41398-018-0189-4.

22.

Prefrontal cortex modulates firing pattern in the nucleus reuniens of the midline thalamus via distinct corticothalamic pathways.

Zimmerman EC, Grace AA.

Eur J Neurosci. 2018 Nov;48(10):3255-3272. doi: 10.1111/ejn.14111. Epub 2018 Sep 24.

23.

Cortical dopamine dysregulation in schizophrenia and its link to stress.

Gomes FV, Grace AA.

Brain. 2018 Jul 1;141(7):1897-1899. doi: 10.1093/brain/awy156. No abstract available.

24.

Ablation of Complex Fractionated Electrograms Improves Outcome in Persistent Atrial Fibrillation of Over 2 Year's Duration.

Martin CA, Curtain JP, Gajendragadkar PR, Begley DA, Fynn SP, Grace AA, Heck PM, Virdee MS, Agarwal S.

J Atr Fibrillation. 2018 Feb 28;10(5):1607. doi: 10.4022/jafib.1607. eCollection 2018 Feb.

25.

Fear extinction disruption in a developmental rodent model of schizophrenia correlates with an impairment in basolateral amygdala-medial prefrontal cortex plasticity.

Uliana DL, Resstel LBM, Grace AA.

Neuropsychopharmacology. 2018 Nov;43(12):2459-2467. doi: 10.1038/s41386-018-0128-3. Epub 2018 Jun 23.

26.

Diazepam reverses increased anxiety-like behavior, social behavior deficit, and dopamine dysregulation following withdrawal from acute amphetamine.

Rincón-Cortés M, Gagnon KG, Dollish HK, Grace AA.

Neuropsychopharmacology. 2018 Nov;43(12):2418-2425. doi: 10.1038/s41386-018-0123-8. Epub 2018 Jun 18.

27.

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kääb S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A.

EMBO J. 2018 Jun 15;37(12). pii: e98133. doi: 10.15252/embj.201798133. Epub 2018 May 15.

28.

Altered brain cannabinoid 1 receptor mRNA expression across postnatal development in the MAM model of schizophrenia.

Gomes FV, Edelson JR, Volk DW, Grace AA.

Schizophr Res. 2018 Nov;201:254-260. doi: 10.1016/j.schres.2018.04.030. Epub 2018 Apr 26.

29.

α7 Nicotinic receptor-modulating agents reverse the hyperdopaminergic tone in the MAM model of schizophrenia.

Neves GA, Grace AA.

Neuropsychopharmacology. 2018 Jul;43(8):1712-1720. doi: 10.1038/s41386-018-0066-0. Epub 2018 Apr 19.

30.

Medial septum differentially regulates dopamine neuron activity in the rat ventral tegmental area and substantia nigra via distinct pathways.

Bortz DM, Grace AA.

Neuropsychopharmacology. 2018 Sep;43(10):2093-2100. doi: 10.1038/s41386-018-0048-2. Epub 2018 Mar 27.

31.

Phenotypic Landscape and Risk Management in Long QT Syndrome: Nudging Forward.

Grace AA, Matthews GDK.

J Am Coll Cardiol. 2018 Apr 17;71(15):1672-1675. doi: 10.1016/j.jacc.2018.02.040. No abstract available.

32.

Continuous and minimally-interrupted direct oral anticoagulant are both safe compared with vitamin K antagonist for atrial fibrillation ablation: An updated meta-analysis.

Ha FJ, Barra S, Brown AJ, Begley DA, Grace AA, Agarwal S.

Int J Cardiol. 2018 Jul 1;262:51-56. doi: 10.1016/j.ijcard.2018.03.095. Epub 2018 Mar 21. Review.

PMID:
29606512
33.

Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis.

Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, McGuire P.

Neuropsychopharmacology. 2018 Dec;43(13):2652-2659. doi: 10.1038/s41386-017-0004-6. Epub 2018 Jan 30. Erratum in: Neuropsychopharmacology. 2018 Oct 2;:.

34.

The Circuitry of Dopamine System Regulation and its Disruption in Schizophrenia: Insights Into Treatment and Prevention.

Grace AA, Gomes FV.

Schizophr Bull. 2019 Jan 1;45(1):148-157. doi: 10.1093/schbul/sbx199. Review.

35.

Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB.

Hasbi A, Perreault ML, Shen MYF, Fan T, Nguyen T, Alijaniaram M, Banasikowski TJ, Grace AA, O'Dowd BF, Fletcher PJ, George SR.

Front Pharmacol. 2018 Jan 4;8:924. doi: 10.3389/fphar.2017.00924. eCollection 2017.

36.

Increased Resting Hippocampal and Basal Ganglia Perfusion in People at Ultra High Risk for Psychosis: Replication in a Second Cohort.

Allen P, Azis M, Modinos G, Bossong MG, Bonoldi I, Samson C, Quinn B, Kempton MJ, Howes OD, Stone JM, Calem M, Perez J, Bhattacharayya S, Broome MR, Grace AA, Zelaya F, McGuire P.

Schizophr Bull. 2018 Oct 17;44(6):1323-1331. doi: 10.1093/schbul/sbx169.

37.

Inhibitory Modulation of Orbitofrontal Cortex on Medial Prefrontal Cortex-Amygdala Information Flow.

Chang CH, Grace AA.

Cereb Cortex. 2018 Jan 1;28(1):1-8. doi: 10.1093/cercor/bhw342.

38.

Divergent effects of acute and repeated quetiapine treatment on dopamine neuron activity in normal vs. chronic mild stress induced hypodopaminergic states.

Moreines JL, Owrutsky ZL, Gagnon KG, Grace AA.

Transl Psychiatry. 2017 Dec 11;7(12):1275. doi: 10.1038/s41398-017-0039-9. Review.

39.

Dopamine System Dysregulation in Major Depressive Disorders.

Belujon P, Grace AA.

Int J Neuropsychopharmacol. 2017 Dec 1;20(12):1036-1046. doi: 10.1093/ijnp/pyx056. Review.

40.

Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research?

Scharfman HE, Kanner AM, Friedman A, Blümcke I, Crocker CE, Cendes F, Diaz-Arrastia R, Förstl H, Fenton AA, Grace AA, Palop J, Morrison J, Nehlig A, Prasad A, Wilcox KS, Jette N, Pohlmann-Eden B.

Epilepsy Behav. 2018 Jan;78:302-312. doi: 10.1016/j.yebeh.2017.09.016. Epub 2017 Oct 31. Review.

41.

Epac-induced ryanodine receptor type 2 activation inhibits sodium currents in atrial and ventricular murine cardiomyocytes.

Valli H, Ahmad S, Sriharan S, Dean LD, Grace AA, Jeevaratnam K, Matthews HR, Huang CL.

Clin Exp Pharmacol Physiol. 2018 Mar;45(3):278-292. doi: 10.1111/1440-1681.12870. Epub 2017 Dec 7.

42.

Cortical GABA in Subjects at Ultra-High Risk of Psychosis: Relationship to Negative Prodromal Symptoms.

Modinos G, Simsek F, Horder J, Bossong M, Bonoldi I, Azis M, Perez J, Broome M, Lythgoe DJ, Stone JM, Howes OD, Murphy DG, Grace AA, Allen P, McGuire P.

Int J Neuropsychopharmacol. 2018 Feb 1;21(2):114-119. doi: 10.1093/ijnp/pyx076.

43.

Psychogenic Stress Activates C-Fos in Nucleus Accumbens-Projecting Neurons of the Hippocampal Ventral Subiculum.

Lipski WJ, Dibble SM, Rinaman L, Grace AA.

Int J Neuropsychopharmacol. 2017 Oct 1;20(10):855-860. doi: 10.1093/ijnp/pyx054.

44.

Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis.

Winton-Brown T, Schmidt A, Roiser JP, Howes OD, Egerton A, Fusar-Poli P, Bunzeck N, Grace AA, Duzel E, Kapur S, McGuire P.

Transl Psychiatry. 2017 Oct 3;7(10):e1245. doi: 10.1038/tp.2017.174. Erratum in: Transl Psychiatry. 2018 Aug 31;8(1):170.

45.

Age-dependent electrocardiographic changes in Pgc-1β deficient murine hearts.

Ahmad S, Valli H, Salvage SC, Grace AA, Jeevaratnam K, Huang CL.

Clin Exp Pharmacol Physiol. 2018 Feb;45(2):174-186. doi: 10.1111/1440-1681.12863. Epub 2017 Nov 29.

46.

Impaired contextual fear-conditioning in MAM rodent model of schizophrenia.

Gill KM, Miller SA, Grace AA.

Schizophr Res. 2018 May;195:343-352. doi: 10.1016/j.schres.2017.08.064. Epub 2017 Sep 18.

47.

Age-dependent atrial arrhythmic phenotype secondary to mitochondrial dysfunction in Pgc-1β deficient murine hearts.

Valli H, Ahmad S, Chadda KR, Al-Hadithi ABAK, Grace AA, Jeevaratnam K, Huang CL.

Mech Ageing Dev. 2017 Oct;167:30-45. doi: 10.1016/j.mad.2017.09.002. Epub 2017 Sep 14.

48.

The effects of ageing and adrenergic challenge on electrocardiographic phenotypes in a murine model of long QT syndrome type 3.

Chadda KR, Ahmad S, Valli H, den Uijl I, Al-Hadithi AB, Salvage SC, Grace AA, Huang CL, Jeevaratnam K.

Sci Rep. 2017 Sep 11;7(1):11070. doi: 10.1038/s41598-017-11210-3.

50.

Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β -/- hearts.

Ahmad S, Valli H, Edling CE, Grace AA, Jeevaratnam K, Huang CL.

Pflugers Arch. 2017 Dec;469(12):1579-1590. doi: 10.1007/s00424-017-2054-3. Epub 2017 Aug 18.

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