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Items: 1 to 50 of 90

1.

Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry.

VanBrunt MP, Shanebeck K, Caldwell Z, Johnson J, Thompson P, Martin T, Dong H, Li G, Xu H, D'Hooge F, Masterson L, Bariola P, Tiberghien A, Ezeadi E, Williams DG, Hartley JA, Howard PW, Grabstein KH, Bowen MA, Marelli M.

Bioconjug Chem. 2015 Nov 18;26(11):2249-60. doi: 10.1021/acs.bioconjchem.5b00359. Epub 2015 Sep 11.

PMID:
26332743
2.

AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use--improves psoriasis in a human xenograft transplantation model.

Stenderup K, Rosada C, Shanebeck K, Brady W, Van Brunt MP, King G, Marelli M, Slagle P, Xu H, Nairn NW, Johnson J, Wang AA, Li G, Thornton KC, Dam TN, Grabstein KH.

Protein Eng Des Sel. 2015 Oct;28(10):467-80. doi: 10.1093/protein/gzv034. Epub 2015 Aug 12.

PMID:
26271488
3.

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects.

Sylwester AW, Mitchell BL, Edgar JB, Taormina C, Pelte C, Ruchti F, Sleath PR, Grabstein KH, Hosken NA, Kern F, Nelson JA, Picker LJ.

J Exp Med. 2005 Sep 5;202(5):673-85.

4.

Development of a CTL vaccine for Her-2/neu using peptide-microspheres and adjuvants.

Mossman SP, Evans LS, Fang H, Staas J, Tice T, Raychaudhuri S, Grabstein KH, Cheever MA, Johnson ME.

Vaccine. 2005 May 20;23(27):3545-54.

PMID:
15855013
5.

Differential regulation of inflammatory cytokine secretion by human dendritic cells upon Chlamydia trachomatis infection.

Gervassi A, Alderson MR, Suchland R, Maisonneuve JF, Grabstein KH, Probst P.

Infect Immun. 2004 Dec;72(12):7231-9.

6.

Human CD8+ T cells recognize the 60-kDa cysteine-rich outer membrane protein from Chlamydia trachomatis.

Gervassi AL, Grabstein KH, Probst P, Hess B, Alderson MR, Fling SP.

J Immunol. 2004 Dec 1;173(11):6905-13.

7.

Functional characterization of class Ia- and non-class Ia-restricted Chlamydia-reactive CD8+ T cell responses in humans.

Gervassi AL, Probst P, Stamm WE, Marrazzo J, Grabstein KH, Alderson MR.

J Immunol. 2003 Oct 15;171(8):4278-86.

8.

Induction of antigen-specific CTL responses using antigens conjugated to short peptide vectors.

Day FH, Zhang Y, Clair P, Grabstein KH, Mazel M, Rees AR, Kaczorek M, Temsamani J.

J Immunol. 2003 Feb 1;170(3):1498-503.

9.

Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER-2 peptide E75 (369-377) combined with granulocyte macrophage colony-stimulating factor in HLA-A2+ patients with metastatic breast and ovarian cancer.

Murray JL, Gillogly ME, Przepiorka D, Brewer H, Ibrahim NK, Booser DJ, Hortobagyi GN, Kudelka AP, Grabstein KH, Cheever MA, Ioannides CG.

Clin Cancer Res. 2002 Nov;8(11):3407-18.

10.

Potent stimulation of the innate immune system by a Leishmania brasiliensis recombinant protein.

Borges MM, Campos-Neto A, Sleath P, Grabstein KH, Morrissey PJ, Skeiky YA, Reed SG.

Infect Immun. 2001 Sep;69(9):5270-7.

11.

Classically restricted human CD8+ T lymphocytes derived from Mycobacterium tuberculosis-infected cells: definition of antigenic specificity.

Lewinsohn DM, Zhu L, Madison VJ, Dillon DC, Fling SP, Reed SG, Grabstein KH, Alderson MR.

J Immunol. 2001 Jan 1;166(1):439-46.

12.

Mycobacterium tuberculosis-reactive CD8+ T lymphocytes: the relative contribution of classical versus nonclassical HLA restriction.

Lewinsohn DM, Briden AL, Reed SG, Grabstein KH, Alderson MR.

J Immunol. 2000 Jul 15;165(2):925-30.

13.
14.

Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB.

Groh V, Rhinehart R, Secrist H, Bauer S, Grabstein KH, Spies T.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):6879-84.

15.

LeIF: a recombinant Leishmania protein that induces an IL-12-mediated Th1 cytokine profile.

Skeiky YA, Kennedy M, Kaufman D, Borges MM, Guderian JA, Scholler JK, Ovendale PJ, Picha KS, Morrissey PJ, Grabstein KH, Campos-Neto A, Reed SG.

J Immunol. 1998 Dec 1;161(11):6171-9.

16.

Proliferative and cytokine responses to class II HER-2/neu-associated peptides in breast cancer patients.

Tuttle TM, Anderson BW, Thompson WE, Lee JE, Sahin A, Smith TL, Grabstein KH, Wharton JT, Ioannides CG, Murray JL.

Clin Cancer Res. 1998 Aug;4(8):2015-24.

17.

Characterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells.

Lewinsohn DM, Alderson MR, Briden AL, Riddell SR, Reed SG, Grabstein KH.

J Exp Med. 1998 May 18;187(10):1633-40.

18.

Human purified protein derivative-specific CD4+ T cells use both CD95-dependent and CD95-independent cytolytic mechanisms.

Lewinsohn DM, Bement TT, Xu J, Lynch DH, Grabstein KH, Reed SG, Alderson MR.

J Immunol. 1998 Mar 1;160(5):2374-9.

19.
20.

The role of the CD28/B7 interaction in the regulation of NK cell responses during infection with Toxoplasma gondii.

Hunter CA, Ellis-Neyer L, Gabriel KE, Kennedy MK, Grabstein KH, Linsley PS, Remington JS.

J Immunol. 1997 Mar 1;158(5):2285-93.

PMID:
9036976
21.

Structure-function studies of interleukin 15 using site-specific mutagenesis, polyethylene glycol conjugation, and homology modeling.

Pettit DK, Bonnert TP, Eisenman J, Srinivasan S, Paxton R, Beers C, Lynch D, Miller B, Yost J, Grabstein KH, Gombotz WR.

J Biol Chem. 1997 Jan 24;272(4):2312-8.

22.

Differential expression of CD22 (Lyb8) on murine B cells.

Erickson LD, Tygrett LT, Bhatia SK, Grabstein KH, Waldschmidt TJ.

Int Immunol. 1996 Jul;8(7):1121-9.

23.

CD40/CD40 ligand interactions are required for T cell-dependent production of interleukin-12 by mouse macrophages.

Kennedy MK, Picha KS, Fanslow WC, Grabstein KH, Alderson MR, Clifford KN, Chin WA, Mohler KM.

Eur J Immunol. 1996 Feb;26(2):370-8.

PMID:
8617306
24.

IL-15 is a novel growth factor for murine gamma delta T cells induced by Salmonella infection.

Nishimura H, Hiromatsu K, Kobayashi N, Grabstein KH, Paxton R, Sugamura K, Bluestone JA, Yoshikai Y.

J Immunol. 1996 Jan 15;156(2):663-9.

PMID:
8543818
25.

Studies evaluating the antitumor activity and toxicity of interleukin-15, a new T cell growth factor: comparison with interleukin-2.

Munger W, DeJoy SQ, Jeyaseelan R Sr, Torley LW, Grabstein KH, Eisenmann J, Paxton R, Cox T, Wick MM, Kerwar SS.

Cell Immunol. 1995 Oct 15;165(2):289-93.

PMID:
7553894
26.
27.

Regulation of murine B cell growth and differentiation by CD30 ligand.

Shanebeck KD, Maliszewski CR, Kennedy MK, Picha KS, Smith CA, Goodwin RG, Grabstein KH.

Eur J Immunol. 1995 Aug;25(8):2147-53.

PMID:
7664777
28.

Interleukin-15: a novel anabolic cytokine for skeletal muscle.

Quinn LS, Haugk KL, Grabstein KH.

Endocrinology. 1995 Aug;136(8):3669-72.

PMID:
7628408
29.

Activation of B lymphocyte maturation by a human follicular dendritic cell line, FDC-1.

Clark EA, Grabstein KH, Gown AM, Skelly M, Kaisho T, Hirano T, Shu GL.

J Immunol. 1995 Jul 15;155(2):545-55.

PMID:
7608535
30.

IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2.

Giri JG, Anderson DM, Kumaki S, Park LS, Grabstein KH, Cosman D.

J Leukoc Biol. 1995 May;57(5):763-6. Review.

PMID:
7759955
31.

IL-12 enhances Th1-type responses in human Leishmania donovani infections.

Ghalib HW, Whittle JA, Kubin M, Hashim FA, el-Hassan AM, Grabstein KH, Trinchieri G, Reed SG.

J Immunol. 1995 May 1;154(9):4623-9.

PMID:
7722314
32.

The effect of in vivo IL-7 deprivation on T cell maturation.

Bhatia SK, Tygrett LT, Grabstein KH, Waldschmidt TJ.

J Exp Med. 1995 Apr 1;181(4):1399-409.

33.

IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation.

Armitage RJ, Macduff BM, Eisenman J, Paxton R, Grabstein KH.

J Immunol. 1995 Jan 15;154(2):483-90.

PMID:
7814861
34.

Interleukin 15 and its receptor.

Cosman D, Kumaki S, Ahdieh M, Eisenman J, Grabstein KH, Paxton R, DuBose R, Friend D, Park LS, Anderson D, et al.

Ciba Found Symp. 1995;195:221-9; discussion 229-33. Review.

PMID:
8724840
35.

Function of the interleukin-2 (IL-2) receptor gamma-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15.

Matthews DJ, Clark PA, Herbert J, Morgan G, Armitage RJ, Kinnon C, Minty A, Grabstein KH, Caput D, Ferrara P, et al.

Blood. 1995 Jan 1;85(1):38-42.

PMID:
7803808
36.

Elevated levels of shed type II IL-1 receptor in sepsis. Potential role for type II receptor in regulation of IL-1 responses.

Giri JG, Wells J, Dower SK, McCall CE, Guzman RN, Slack J, Bird TA, Shanebeck K, Grabstein KH, Sims JE, et al.

J Immunol. 1994 Dec 15;153(12):5802-9.

PMID:
7989776
37.

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

Peschon JJ, Morrissey PJ, Grabstein KH, Ramsdell FJ, Maraskovsky E, Gliniak BC, Park LS, Ziegler SF, Williams DE, Ware CB, Meyer JD, Davison BL.

J Exp Med. 1994 Nov 1;180(5):1955-60.

38.

IL-10 mediates susceptibility to Trypanosoma cruzi infection.

Reed SG, Brownell CE, Russo DM, Silva JS, Grabstein KH, Morrissey PJ.

J Immunol. 1994 Oct 1;153(7):3135-40.

PMID:
8089491
39.

Interleukin-12 regulates the proliferation of Th1, but not Th2 or Th0, clones.

Kennedy MK, Picha KS, Shanebeck KD, Anderson DM, Grabstein KH.

Eur J Immunol. 1994 Oct;24(10):2271-8.

PMID:
7925555
40.

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor.

Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, Beers C, Richardson J, Schoenborn MA, Ahdieh M, et al.

Science. 1994 May 13;264(5161):965-8.

PMID:
8178155
41.

Induction of B cell costimulatory function by recombinant murine CD40 ligand.

Kennedy MK, Mohler KM, Shanebeck KD, Baum PR, Picha KS, Otten-Evans CA, Janeway CA Jr, Grabstein KH.

Eur J Immunol. 1994 Jan;24(1):116-23.

PMID:
7517359
42.

CD40L: a multi-functional ligand.

Armitage RJ, Maliszewski CR, Alderson MR, Grabstein KH, Spriggs MK, Fanslow WC.

Semin Immunol. 1993 Dec;5(6):401-12. Review.

PMID:
7510138
43.

IL-6 down-modulates the cytokine-enhanced antileishmanial activity in human macrophages.

Hatzigeorgiou DE, He S, Sobel J, Grabstein KH, Hafner A, Ho JL.

J Immunol. 1993 Oct 1;151(7):3682-92.

PMID:
8397259
44.

Antigen-reactive gamma delta T cells in human leishmaniasis.

Russo DM, Armitage RJ, Barral-Netto M, Barral A, Grabstein KH, Reed SG.

J Immunol. 1993 Oct 1;151(7):3712-8.

PMID:
8376802
45.

Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.

Grabstein KH, Waldschmidt TJ, Finkelman FD, Hess BW, Alpert AR, Boiani NE, Namen AE, Morrissey PJ.

J Exp Med. 1993 Jul 1;178(1):257-64.

46.

Molecular characterization of the early activation antigen CD69: a type II membrane glycoprotein related to a family of natural killer cell activation antigens.

Ziegler SF, Ramsdell F, Hjerrild KA, Armitage RJ, Grabstein KH, Hennen KB, Farrah T, Fanslow WC, Shevach EM, Alderson MR.

Eur J Immunol. 1993 Jul;23(7):1643-8.

PMID:
8100776
47.

The regulation of T cell-dependent antibody formation in vitro by CD40 ligand and IL-2.

Grabstein KH, Maliszewski CR, Shanebeck K, Sato TA, Spriggs MK, Fanslow WC, Armitage RJ.

J Immunol. 1993 Apr 15;150(8 Pt 1):3141-7.

PMID:
7682232
48.

Recombinant soluble murine IL-4 receptor can inhibit or enhance IgE responses in vivo.

Sato TA, Widmer MB, Finkelman FD, Madani H, Jacobs CA, Grabstein KH, Maliszewski CR.

J Immunol. 1993 Apr 1;150(7):2717-23.

PMID:
8454851
49.

Characterization of responses of normal human T cells to Trypanosoma cruzi antigens.

Piuvezam MR, Russo DM, Burns JM Jr, Skeiky YA, Grabstein KH, Reed SG.

J Immunol. 1993 Feb 1;150(3):916-24.

PMID:
8423347
50.

Multiple cytokine secretion by IL-7-stimulated human T cells.

Armitage RJ, Macduff BM, Ziegler SF, Grabstein KH.

Cytokine. 1992 Nov;4(6):461-9.

PMID:
1292630

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