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Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.

Soni A, Li F, Wang Y, Grabos M, Krieger LM, Chaudhary S, Hasan MSM, Ahmed M, Coleman CN, Teicher BA, Piekarz RL, Wang D, Iliakis GE.

Mol Cancer Ther. 2018 Oct;17(10):2206-2216. doi: 10.1158/1535-7163.MCT-17-0836. Epub 2018 Jul 3.


Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.

Soni A, Siemann M, Grabos M, Murmann T, Pantelias GE, Iliakis G.

Nucleic Acids Res. 2014 Jun;42(10):6380-92. doi: 10.1093/nar/gku298. Epub 2014 Apr 19.

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