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Items: 29

1.

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

Fujino N, Brand OJ, Morgan DJ, Fujimori T, Grabiec AM, Jagger CP, Maciewicz RA, Yamada M, Itakura K, Sugiura H, Ichinose M, Hussell T.

J Exp Med. 2019 Sep 2;216(9):2184-2201. doi: 10.1084/jem.20171978. Epub 2019 Jul 9.

PMID:
31289116
2.

BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients.

Maksylewicz A, Bysiek A, Lagosz KB, Macina JM, Kantorowicz M, Bereta G, Sochalska M, Gawron K, Chomyszyn-Gajewska M, Potempa J, Grabiec AM.

Front Immunol. 2019 Apr 30;10:933. doi: 10.3389/fimmu.2019.00933. eCollection 2019.

3.

An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness.

Patel DF, Peiró T, Shoemark A, Akthar S, Walker SA, Grabiec AM, Jackson PL, Hussell T, Gaggar A, Xu X, Trevor JL, Li J, Steele C, Tavernier G, Blalock JE, Niven RM, Gregory LG, Simpson A, Lloyd CM, Snelgrove RJ.

Sci Transl Med. 2018 Aug 22;10(455). pii: eaaq0693. doi: 10.1126/scitranslmed.aaq0693.

4.

Control of cytokine mRNA degradation by the histone deacetylase inhibitor ITF2357 in rheumatoid arthritis fibroblast-like synoviocytes: beyond transcriptional regulation.

Angiolilli C, Kabala PA, Grabiec AM, Rossato M, Lai WS, Fossati G, Mascagni P, Steinkühler C, Blackshear PJ, Reedquist KA, Baeten DL, Radstake TRDJ.

Arthritis Res Ther. 2018 Jul 20;20(1):148. doi: 10.1186/s13075-018-1638-4.

5.

TIMP-1 association with collagen type I overproduction in hereditary gingival fibromatosis.

Gawron K, Ochała-Kłos A, Nowakowska Z, Bereta G, Łazarz-Bartyzel K, Grabiec AM, Plakwicz P, Górska R, Fertala A, Chomyszyn-Gajewska M, Potempa J.

Oral Dis. 2018 Nov;24(8):1581-1590. doi: 10.1111/odi.12938. Epub 2018 Aug 14.

PMID:
29989318
6.

Culture of Human Monocyte-Derived Macrophages.

Kelly A, Grabiec AM, Travis MA.

Methods Mol Biol. 2018;1784:1-11. doi: 10.1007/978-1-4939-7837-3_1.

PMID:
29761383
7.

Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers.

Grabiec AM, Goenka A, Fife ME, Fujimori T, Hussell T.

Eur J Immunol. 2018 May;48(5):855-860. doi: 10.1002/eji.201747283. Epub 2018 Feb 22.

8.

Epigenetic regulation in bacterial infections: targeting histone deacetylases.

Grabiec AM, Potempa J.

Crit Rev Microbiol. 2018 May;44(3):336-350. doi: 10.1080/1040841X.2017.1373063. Epub 2017 Oct 3. Review.

9.

Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes.

Kabala PA, Angiolilli C, Yeremenko N, Grabiec AM, Giovannone B, Pots D, Radstake TR, Baeten D, Reedquist KA.

Arthritis Res Ther. 2017 Sep 18;19(1):207. doi: 10.1186/s13075-017-1386-x.

10.

Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma.

Grabiec AM, Denny N, Doherty JA, Happonen KE, Hankinson J, Connolly E, Fife ME, Fujimori T, Fujino N, Goenka A, Holden S, Tavernier G, Shah R, Cook PC, MacDonald AS, Niven RM, Dahlbäck B, Fowler SJ, Simpson A, Hussell T.

J Allergy Clin Immunol. 2017 Oct;140(4):1144-1146.e4. doi: 10.1016/j.jaci.2017.03.024. Epub 2017 Apr 12. No abstract available.

11.

Reversal of TREM-1 ectodomain shedding and improved bacterial clearance by intranasal metalloproteinase inhibitors.

Weiss G, Lai C, Fife ME, Grabiec AM, Tildy B, Snelgrove RJ, Xin G, Lloyd CM, Hussell T.

Mucosal Immunol. 2017 Jul;10(4):1021-1030. doi: 10.1038/mi.2016.104. Epub 2016 Dec 14.

PMID:
27966555
12.

Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes.

Angiolilli C, Kabala PA, Grabiec AM, Van Baarsen IM, Ferguson BS, García S, Malvar Fernandez B, McKinsey TA, Tak PP, Fossati G, Mascagni P, Baeten DL, Reedquist KA.

Ann Rheum Dis. 2017 Jan;76(1):277-285. doi: 10.1136/annrheumdis-2015-209064. Epub 2016 Jul 25.

13.

Immunopathology of lung diseases: introduction for the special issue.

Hussell T, Grabiec AM.

Semin Immunopathol. 2016 Jul;38(4):407-8. doi: 10.1007/s00281-016-0572-2. Epub 2016 May 19. No abstract available.

PMID:
27193138
14.

The role of airway macrophages in apoptotic cell clearance following acute and chronic lung inflammation.

Grabiec AM, Hussell T.

Semin Immunopathol. 2016 Jul;38(4):409-23. doi: 10.1007/s00281-016-0555-3. Epub 2016 Mar 8. Review.

15.

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

Fujimori T, Grabiec AM, Kaur M, Bell TJ, Fujino N, Cook PC, Svedberg FR, MacDonald AS, Maciewicz RA, Singh D, Hussell T.

Mucosal Immunol. 2015 Sep;8(5):1021-1030. doi: 10.1038/mi.2014.129. Epub 2015 Jan 21.

16.

The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts.

Klein K, Kabala PA, Grabiec AM, Gay RE, Kolling C, Lin LL, Gay S, Tak PP, Prinjha RK, Ospelt C, Reedquist KA.

Ann Rheum Dis. 2016 Feb;75(2):422-9. doi: 10.1136/annrheumdis-2014-205809. Epub 2014 Dec 2.

PMID:
25467295
17.

Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression.

Angiolilli C, Grabiec AM, Ferguson BS, Ospelt C, Malvar Fernandez B, van Es IE, van Baarsen LG, Gay S, McKinsey TA, Tak PP, Baeten DL, Reedquist KA.

Ann Rheum Dis. 2016 Feb;75(2):430-8. doi: 10.1136/annrheumdis-2014-205635. Epub 2014 Dec 1.

18.

JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis.

Grabiec AM, Angiolilli C, Hartkamp LM, van Baarsen LG, Tak PP, Reedquist KA.

Ann Rheum Dis. 2015 Sep;74(9):1763-71. doi: 10.1136/annrheumdis-2013-203610. Epub 2014 May 8.

PMID:
24812285
19.

The ascent of acetylation in the epigenetics of rheumatoid arthritis.

Grabiec AM, Reedquist KA.

Nat Rev Rheumatol. 2013 May;9(5):311-8. doi: 10.1038/nrrheum.2013.17. Epub 2013 Feb 26. Review.

PMID:
23439035
20.

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay.

Grabiec AM, Korchynskyi O, Tak PP, Reedquist KA.

Ann Rheum Dis. 2012 Mar;71(3):424-31. doi: 10.1136/ard.2011.154211. Epub 2011 Sep 27.

21.

Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well as therapeutic targets.

de Launay D, van de Sande MG, de Hair MJ, Grabiec AM, van de Sande GP, Lehmann KA, Wijbrandts CA, van Baarsen LG, Gerlag DM, Tak PP, Reedquist KA.

Ann Rheum Dis. 2012 Mar;71(3):415-23. doi: 10.1136/ard.2010.143529. Epub 2011 Sep 27.

22.

Function of histone deacetylase inhibitors in inflammation.

Grabiec AM, Tak PP, Reedquist KA.

Crit Rev Immunol. 2011;31(3):233-63. Review.

PMID:
21740352
23.

Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis.

de Launay D, Vreijling J, Hartkamp LM, Karpus ON, Abreu JR, van Maanen MA, Sanders ME, Grabiec AM, Hamann J, Ørum H, Vervoordeldonk MJ, Fluiter K, Tak PP, Reedquist KA.

Am J Pathol. 2010 Dec;177(6):3010-24. doi: 10.2353/ajpath.2010.091053. Epub 2010 Oct 22.

24.

Histone deacetylases in RA: epigenetics and epiphenomena.

Grabiec AM, Reedquist KA.

Arthritis Res Ther. 2010;12(5):142. doi: 10.1186/ar3137. Epub 2010 Oct 11.

25.

Sustained T cell Rap1 signaling is protective in the collagen-induced arthritis model of rheumatoid arthritis.

Abreu JR, Krausz S, Dontje W, Grabiec AM, de Launay D, Nolte MA, Tak PP, Reedquist KA.

Arthritis Rheum. 2010 Nov;62(11):3289-99. doi: 10.1002/art.27656.

26.

Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue.

Grabiec AM, Krausz S, de Jager W, Burakowski T, Groot D, Sanders ME, Prakken BJ, Maslinski W, Eldering E, Tak PP, Reedquist KA.

J Immunol. 2010 Mar 1;184(5):2718-28. doi: 10.4049/jimmunol.0901467. Epub 2010 Jan 25.

27.

The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue.

Abreu JR, de Launay D, Sanders ME, Grabiec AM, van de Sande MG, Tak PP, Reedquist KA.

Arthritis Res Ther. 2009;11(4):R121. doi: 10.1186/ar2785. Epub 2009 Aug 13.

28.

The presumed hyporesponsive behavior of rheumatoid arthritis T lymphocytes can be attributed to spontaneous ex vivo apoptosis rather than defects in T cell receptor signaling.

Abreu JR, Grabiec AM, Krausz S, Spijker R, Burakowski T, Maslinski W, Eldering E, Tak PP, Reedquist KA.

J Immunol. 2009 Jul 1;183(1):621-30. doi: 10.4049/jimmunol.0803278. Epub 2009 Jun 12.

29.

Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

Grabiec AM, Tak PP, Reedquist KA.

Arthritis Res Ther. 2008;10(5):226. doi: 10.1186/ar2489. Epub 2008 Oct 17. Review.

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