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Items: 1 to 50 of 132

1.

A multiscale model of mechanotransduction by the ankyrin chains of the NOMPC channel.

Argudo D, Capponi S, Bethel NP, Grabe M.

J Gen Physiol. 2019 Feb 6. pii: jgp.201812266. doi: 10.1085/jgp.201812266. [Epub ahead of print]

PMID:
30728217
2.

Chemically induced vesiculation as a platform for studying TMEM16F activity.

Han TW, Ye W, Bethel NP, Zubia M, Kim A, Li KH, Burlingame AL, Grabe M, Jan YN, Jan LY.

Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1309-1318. doi: 10.1073/pnas.1817498116. Epub 2019 Jan 8.

PMID:
30622179
3.

Inhibitor binding mode and allosteric regulation of Na+-glucose symporters.

Bisignano P, Ghezzi C, Jo H, Polizzi NF, Althoff T, Kalyanaraman C, Friemann R, Jacobson MP, Wright EM, Grabe M.

Nat Commun. 2018 Dec 7;9(1):5245. doi: 10.1038/s41467-018-07700-1.

4.
5.

Cilia-Associated Oxysterols Activate Smoothened.

Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald JG, Xu L, Beachy PA, Reiter JF.

Mol Cell. 2018 Oct 18;72(2):316-327.e5. doi: 10.1016/j.molcel.2018.08.034.

PMID:
30340023
6.

Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule.

Bokoch MP, Jo H, Valcourt JR, Srinivasan Y, Pan AC, Capponi S, Grabe M, Dror RO, Shaw DE, DeGrado WF, Coughlin SR.

Biochemistry. 2018 Oct 2;57(39):5748-5758. doi: 10.1021/acs.biochem.8b00577. Epub 2018 Aug 27.

PMID:
30102523
7.

Asymptomatic Bacteriuria is Harmless and Even Protective: Don't Treat if You Don't Have a Very Specific Reason.

Wullt B, Sundén F, Grabe M.

Eur Urol Focus. 2019 Jan;5(1):15-16. doi: 10.1016/j.euf.2018.07.004. Epub 2018 Jul 18.

PMID:
30030090
8.

Antimicrobial Stewardship: What We All Just Need to Know.

Grabe MJ, Resman F.

Eur Urol Focus. 2019 Jan;5(1):46-49. doi: 10.1016/j.euf.2018.06.012. Epub 2018 Jun 30. Review.

PMID:
29970303
9.

Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.

Wahlgren WY, Dunevall E, North RA, Paz A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ, Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S, Friemann R.

Nat Commun. 2018 May 1;9(1):1753. doi: 10.1038/s41467-018-04045-7.

10.

Conformational transitions of the sodium-dependent sugar transporter, vSGLT.

Paz A, Claxton DP, Kumar JP, Kazmier K, Bisignano P, Sharma S, Nolte SA, Liwag TM, Nayak V, Wright EM, Grabe M, Mchaourab HS, Abramson J.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2742-E2751. doi: 10.1073/pnas.1718451115. Epub 2018 Mar 5.

11.

The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel.

Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan YN, Grabe M, Jan LY.

Neuron. 2018 Mar 7;97(5):1063-1077.e4. doi: 10.1016/j.neuron.2018.01.048. Epub 2018 Feb 22.

PMID:
29478917
12.

Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1.

Bergdoll LA, Lerch MT, Patrick JW, Belardo K, Altenbach C, Bisignano P, Laganowsky A, Grabe M, Hubbell WL, Abramson J.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E172-E179. doi: 10.1073/pnas.1715464115. Epub 2017 Dec 26.

13.

Re: Is Preoperative Assessment and Treatment of Asymptomatic Bacteriuria Necessary for Reducing the Risk of Postoperative Symptomatic Urinary Tract Infection After Urologic Surgical Procedures?

Grabe M, Wullt B.

Eur Urol. 2017 Dec 7. pii: S0302-2838(17)31025-4. doi: 10.1016/j.eururo.2017.11.033. [Epub ahead of print] No abstract available.

PMID:
29224913
14.

Grey Zones in the Field of Urinary Tract Infections.

Bjerklund Johansen TE, Bonkat G, Cai T, Tandogdu Z, Wagenlehner F, Grabe M.

Eur Urol Focus. 2016 Oct;2(4):460-462. doi: 10.1016/j.euf.2016.03.012. Epub 2016 Apr 13.

PMID:
28723480
15.

How to Use Antimicrobial Prophylaxis in Urological Procedures.

Cai T, Bonkat G, Tandogdu Z, Bartoletti R, Wagenlehner FME, Grabe M, Johansen TEB.

Eur Urol Focus. 2016 Oct;2(4):348-350. doi: 10.1016/j.euf.2016.02.010. Epub 2016 Mar 4.

PMID:
28723464
16.

Re: Treatment Duration of Febrile Urinary Tract Infection: A Pragmatic Randomized, Double-blind, Placebo-controlled Non-inferiority Trial in Men and Women.

Grabe MJ.

Eur Urol. 2017 Oct;72(4):652. doi: 10.1016/j.eururo.2017.05.042. Epub 2017 Jun 8. No abstract available.

PMID:
28602200
17.

Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates.

Guerriero CJ, Reutter KR, Augustine AA, Preston GM, Weiberth KF, Mackie TD, Cleveland-Rubeor HC, Bethel NP, Callenberg KM, Nakatsukasa K, Grabe M, Brodsky JL.

Mol Biol Cell. 2017 Jul 15;28(15):2076-2090. doi: 10.1091/mbc.E17-03-0184. Epub 2017 May 24.

18.

New Continuum Approaches for Determining Protein-Induced Membrane Deformations.

Argudo D, Bethel NP, Marcoline FV, Wolgemuth CW, Grabe M.

Biophys J. 2017 May 23;112(10):2159-2172. doi: 10.1016/j.bpj.2017.03.040.

19.

Atomistic insight into lipid translocation by a TMEM16 scramblase.

Bethel NP, Grabe M.

Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):14049-14054. Epub 2016 Nov 21.

20.

Tailored perioperative antimicrobial prophylaxis in urological surgery: myth or reality?

Grabe MJ, Lundström KJ.

Curr Opin Urol. 2017 Mar;27(2):112-119. doi: 10.1097/MOU.0000000000000363. Review.

PMID:
27861259
21.

Catheter-associated urinary tract infections and other infections in patients hospitalized for acute stroke: A prospective cohort study of two different silicone catheters.

Stenzelius K, Laszlo L, Madeja M, Pessah-Rasmusson H, Grabe M.

Scand J Urol. 2016 Dec;50(6):483-488. Epub 2016 Jun 21.

PMID:
27328334
22.

A mathematical model of osteoclast acidification during bone resorption.

Marcoline FV, Ishida Y, Mindell JA, Nayak S, Grabe M.

Bone. 2016 Dec;93:167-180. doi: 10.1016/j.bone.2016.09.007. Epub 2016 Sep 17.

23.

Stochastic steps in secondary active sugar transport.

Adelman JL, Ghezzi C, Bisignano P, Loo DD, Choe S, Abramson J, Rosenberg JM, Wright EM, Grabe M.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3960-6. doi: 10.1073/pnas.1525378113. Epub 2016 Jun 20.

24.

Direct observation of proton pumping by a eukaryotic P-type ATPase.

Veshaguri S, Christensen SM, Kemmer GC, Ghale G, Møller MP, Lohr C, Christensen AL, Justesen BH, Jørgensen IL, Schiller J, Hatzakis NS, Grabe M, Pomorski TG, Stamou D.

Science. 2016 Mar 25;351(6280):1469-73. doi: 10.1126/science.aad6429.

25.

Continuum descriptions of membranes and their interaction with proteins: Towards chemically accurate models.

Argudo D, Bethel NP, Marcoline FV, Grabe M.

Biochim Biophys Acta. 2016 Jul;1858(7 Pt B):1619-34. doi: 10.1016/j.bbamem.2016.02.003. Epub 2016 Feb 4. Review.

26.

Asymptomatic Bacteriuria in Clinical Urological Practice: Preoperative Control of Bacteriuria and Management of Recurrent UTI.

Cai T, Mazzoli S, Lanzafame P, Caciagli P, Malossini G, Nesi G, Wagenlehner FM, Köves B, Pickard R, Grabe M, Bjerklund Johansen TE, Bartoletti R.

Pathogens. 2016 Jan 5;5(1). pii: E4. doi: 10.3390/pathogens5010004.

27.

Antimicrobial resistance in urosepsis: outcomes from the multinational, multicenter global prevalence of infections in urology (GPIU) study 2003-2013.

Tandoğdu Z, Bartoletti R, Cai T, Çek M, Grabe M, Kulchavenya E, Köves B, Menon V, Naber K, Perepanova T, Tenke P, Wullt B, Johansen TE, Wagenlehner F.

World J Urol. 2016 Aug;34(8):1193-200. doi: 10.1007/s00345-015-1722-1. Epub 2015 Dec 11.

28.

Contemporary Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome.

Magistro G, Wagenlehner FM, Grabe M, Weidner W, Stief CG, Nickel JC.

Eur Urol. 2016 Feb;69(2):286-97. doi: 10.1016/j.eururo.2015.08.061. Epub 2015 Sep 26. Review.

PMID:
26411805
29.
30.

WESTPA: an interoperable, highly scalable software package for weighted ensemble simulation and analysis.

Zwier MC, Adelman JL, Kaus JW, Pratt AJ, Wong KF, Rego NB, Suárez E, Lettieri S, Wang DW, Grabe M, Zuckerman DM, Chong LT.

J Chem Theory Comput. 2015 Feb 10;11(2):800-9. doi: 10.1021/ct5010615.

31.

Membrane Protein Properties Revealed through Data-Rich Electrostatics Calculations.

Marcoline FV, Bethel N, Guerriero CJ, Brodsky JL, Grabe M.

Structure. 2015 Aug 4;23(8):1526-1537. doi: 10.1016/j.str.2015.05.014. Epub 2015 Jun 25.

32.

De novo design of a transmembrane Zn²⁺-transporting four-helix bundle.

Joh NH, Wang T, Bhate MP, Acharya R, Wu Y, Grabe M, Hong M, Grigoryan G, DeGrado WF.

Science. 2014 Dec 19;346(6216):1520-4. doi: 10.1126/science.1261172.

33.

Structure-guided simulations illuminate the mechanism of ATP transport through VDAC1.

Choudhary OP, Paz A, Adelman JL, Colletier JP, Abramson J, Grabe M.

Nat Struct Mol Biol. 2014 Jul;21(7):626-32. doi: 10.1038/nsmb.2841. Epub 2014 Jun 8.

34.

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.

Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM.

Nat Med. 2014 Jun;20(6):624-32. doi: 10.1038/nm.3543. Epub 2014 May 18.

35.

Structural determinants of water permeation through the sodium-galactose transporter vSGLT.

Adelman JL, Sheng Y, Choe S, Abramson J, Wright EM, Rosenberg JM, Grabe M.

Biophys J. 2014 Mar 18;106(6):1280-9. doi: 10.1016/j.bpj.2014.01.006.

36.

Continuum approaches to understanding ion and peptide interactions with the membrane.

Latorraca NR, Callenberg KM, Boyle JP, Grabe M.

J Membr Biol. 2014 May;247(5):395-408. doi: 10.1007/s00232-014-9646-z. Epub 2014 Mar 21.

37.

Antibacterial membrane attack by a pore-forming intestinal C-type lectin.

Mukherjee S, Zheng H, Derebe MG, Callenberg KM, Partch CL, Rollins D, Propheter DC, Rizo J, Grabe M, Jiang QX, Hooper LV.

Nature. 2014 Jan 2;505(7481):103-7. doi: 10.1038/nature12729. Epub 2013 Nov 20.

38.

Antibiotic stewardship: a call for action by the urologic community.

Wagenlehner FM, Bartoletti R, Cek M, Grabe M, Kahlmeter G, Pickard R, Bjerklund-Johansen TE.

Eur Urol. 2013 Sep;64(3):358-60. doi: 10.1016/j.eururo.2013.05.044. Epub 2013 May 29.

PMID:
23746854
39.

A model of lysosomal pH regulation.

Ishida Y, Nayak S, Mindell JA, Grabe M.

J Gen Physiol. 2013 Jun;141(6):705-20. doi: 10.1085/jgp.201210930.

40.

Simulating rare events using a weighted ensemble-based string method.

Adelman JL, Grabe M.

J Chem Phys. 2013 Jan 28;138(4):044105. doi: 10.1063/1.4773892.

41.

Reply from Authors re: Riccardo Bartoletti, Tommaso Cai. Prostate Biopsies Should Be Performed According to a Standard of Care. Eur Urol 2013;63:528-9.

Wagenlehner F, van Oostrum E, Tenke P, Tandogdu Z, Cek M, Grabe M, Wullt B, Pickard R, Naber KG, Pilatz A, Weidner W, Bjerklund-Johansen TE.

Eur Urol. 2013 Mar;63(3):529-30. doi: 10.1016/j.eururo.2012.07.037. Epub 2012 Jul 25. No abstract available.

PMID:
22868669
42.

Does imaging modality used for percutaneous renal access make a difference? A matched case analysis.

Andonian S, Scoffone CM, Louie MK, Gross AJ, Grabe M, Daels FP, Shah HN, de la Rosette JJ; CROES PCNL Study Group.

J Endourol. 2013 Jan;27(1):24-8. doi: 10.1089/end.2012.0347. Epub 2012 Oct 17.

PMID:
22834999
43.

Membrane bending is critical for the stability of voltage sensor segments in the membrane.

Callenberg KM, Latorraca NR, Grabe M.

J Gen Physiol. 2012 Jul;140(1):55-68. doi: 10.1085/jgp.201110766.

44.

Infective complications after prostate biopsy: outcome of the Global Prevalence Study of Infections in Urology (GPIU) 2010 and 2011, a prospective multinational multicentre prostate biopsy study.

Wagenlehner FM, van Oostrum E, Tenke P, Tandogdu Z, Çek M, Grabe M, Wullt B, Pickard R, Naber KG, Pilatz A, Weidner W, Bjerklund-Johansen TE; GPIU investigators.

Eur Urol. 2013 Mar;63(3):521-7. doi: 10.1016/j.eururo.2012.06.003. Epub 2012 Jun 12.

PMID:
22704727
45.

Categorisation of complications and validation of the Clavien score for percutaneous nephrolithotomy.

de la Rosette JJ, Opondo D, Daels FP, Giusti G, Serrano A, Kandasami SV, Wolf JS Jr, Grabe M, Gravas S; CROES PCNL Study Group.

Eur Urol. 2012 Aug;62(2):246-55. doi: 10.1016/j.eururo.2012.03.055. Epub 2012 Apr 4.

PMID:
22487016
46.

Simulations of the alternating access mechanism of the sodium symporter Mhp1.

Adelman JL, Dale AL, Zwier MC, Bhatt D, Chong LT, Zuckerman DM, Grabe M.

Biophys J. 2011 Nov 16;101(10):2399-407. doi: 10.1016/j.bpj.2011.09.061. Epub 2011 Nov 15.

47.

Role of hexaminolevulinate-guided fluorescence cystoscopy in bladder cancer: critical analysis of the latest data and European guidance.

Malmström PU, Grabe M, Haug ES, Hellström P, Hermann GG, Mogensen K, Raitanen M, Wahlqvist R.

Scand J Urol Nephrol. 2012 Apr;46(2):108-16. doi: 10.3109/00365599.2011.633279. Epub 2011 Nov 16.

PMID:
22087730
48.

Critical review of current definitions of urinary tract infections and proposal of an EAU/ESIU classification system.

Johansen TE, Botto H, Cek M, Grabe M, Tenke P, Wagenlehner FM, Naber KG.

Int J Antimicrob Agents. 2011 Dec;38 Suppl:64-70. doi: 10.1016/j.ijantimicag.2011.09.009. Epub 2011 Oct 21. Review.

PMID:
22018988
49.

[Antibiotic prophylaxis in urology].

Wagenlehner FM, Grabe M, Naber KG, Bjerklund Johansen TE, Naber CK, Weidner W.

Urologe A. 2011 Nov;50(11):1469-78; quiz 1479-80. doi: 10.1007/s00120-011-2661-0. German.

PMID:
21997660
50.

Antibiotic prophylaxis in urological surgery, a European viewpoint.

Grabe M.

Int J Antimicrob Agents. 2011 Dec;38 Suppl:58-63. doi: 10.1016/j.ijantimicag.2011.09.008. Epub 2011 Oct 12. Review.

PMID:
21996404

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