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Items: 1 to 50 of 61

1.

uORF-Tools-Workflow for the determination of translation-regulatory upstream open reading frames.

Scholz A, Eggenhofer F, Gelhausen R, Grüning B, Zarnack K, Brüne B, Backofen R, Schmid T.

PLoS One. 2019 Sep 12;14(9):e0222459. doi: 10.1371/journal.pone.0222459. eCollection 2019.

2.

The bio.tools registry of software tools and data resources for the life sciences.

Ison J, Ienasescu H, Chmura P, Rydza E, Ménager H, Kalaš M, Schwämmle V, Grüning B, Beard N, Lopez R, Duvaud S, Stockinger H, Persson B, Vařeková RS, Raček T, Vondrášek J, Peterson H, Salumets A, Jonassen I, Hooft R, Nyrönen T, Valencia A, Capella S, Gelpí J, Zambelli F, Savakis B, Leskošek B, Rapacki K, Blanchet C, Jimenez R, Oliveira A, Vriend G, Collin O, van Helden J, Løngreen P, Brunak S.

Genome Biol. 2019 Aug 12;20(1):164. doi: 10.1186/s13059-019-1772-6.

3.

Software engineering for scientific big data analysis.

Grüning BA, Lampa S, Vaudel M, Blankenberg D.

Gigascience. 2019 May 1;8(5). pii: giz054. doi: 10.1093/gigascience/giz054.

4.

The RNA workbench 2.0: next generation RNA data analysis.

Fallmann J, Videm P, Bagnacani A, Batut B, Doyle MA, Klingstrom T, Eggenhofer F, Stadler PF, Backofen R, Grüning B.

Nucleic Acids Res. 2019 Jul 2;47(W1):W511-W515. doi: 10.1093/nar/gkz353.

5.

Alteration of the Route to Menaquinone towards Isochorismate-Derived Metabolites.

Fries A, Mazzaferro LS, Grüning B, Bisel P, Stibal K, Buchholz PCF, Pleiss J, Sprenger GA, Müller M.

Chembiochem. 2019 Jul 1;20(13):1672-1677. doi: 10.1002/cbic.201900050. Epub 2019 May 24.

6.

Biomolecular Reaction and Interaction Dynamics Global Environment (BRIDGE).

Senapathi T, Bray S, Barnett CB, Grüning B, Naidoo KJ.

Bioinformatics. 2019 Sep 15;35(18):3508-3509. doi: 10.1093/bioinformatics/btz107.

PMID:
30759217
7.

Pou5f3, SoxB1, and Nanog remodel chromatin on high nucleosome affinity regions at zygotic genome activation.

Veil M, Yampolsky LY, Grüning B, Onichtchouk D.

Genome Res. 2019 Mar;29(3):383-395. doi: 10.1101/gr.240572.118. Epub 2019 Jan 23.

8.

Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome.

Nührenberg TG, Cederqvist M, Marini F, Stratz C, Grüning BA, Trenk D, Binder H, Gilsbach R, Neumann FJ, Hein L.

Biomed Res Int. 2018 Nov 1;2018:8989252. doi: 10.1155/2018/8989252. eCollection 2018.

9.

Update on the moFF Algorithm for Label-Free Quantitative Proteomics.

Argentini A, Staes A, Grüning B, Mehta S, Easterly C, Griffin TJ, Jagtap P, Impens F, Martens L.

J Proteome Res. 2019 Feb 1;18(2):728-731. doi: 10.1021/acs.jproteome.8b00708. Epub 2018 Dec 14.

PMID:
30511867
10.

Parkour LIMS: high-quality sample preparation in next generation sequencing.

Anatskiy E, Ryan DP, Grüning BA, Arrigoni L, Manke T, Bönisch U.

Bioinformatics. 2019 Apr 15;35(8):1422-1424. doi: 10.1093/bioinformatics/bty820.

PMID:
30239601
11.

Bioconda: sustainable and comprehensive software distribution for the life sciences.

Grüning B, Dale R, Sjödin A, Chapman BA, Rowe J, Tomkins-Tinch CH, Valieris R, Köster J; Bioconda Team.

Nat Methods. 2018 Jul;15(7):475-476. doi: 10.1038/s41592-018-0046-7. No abstract available.

PMID:
29967506
12.

Community-Driven Data Analysis Training for Biology.

Batut B, Hiltemann S, Bagnacani A, Baker D, Bhardwaj V, Blank C, Bretaudeau A, Brillet-Guéguen L, Čech M, Chilton J, Clements D, Doppelt-Azeroual O, Erxleben A, Freeberg MA, Gladman S, Hoogstrate Y, Hotz HR, Houwaart T, Jagtap P, Larivière D, Le Corguillé G, Manke T, Mareuil F, Ramírez F, Ryan D, Sigloch FC, Soranzo N, Wolff J, Videm P, Wolfien M, Wubuli A, Yusuf D; Galaxy Training Network, Taylor J, Backofen R, Nekrutenko A, Grüning B.

Cell Syst. 2018 Jun 27;6(6):752-758.e1. doi: 10.1016/j.cels.2018.05.012.

13.

Practical Computational Reproducibility in the Life Sciences.

Grüning B, Chilton J, Köster J, Dale R, Soranzo N, van den Beek M, Goecks J, Backofen R, Nekrutenko A, Taylor J.

Cell Syst. 2018 Jun 27;6(6):631-635. doi: 10.1016/j.cels.2018.03.014.

14.

Galaxy HiCExplorer: a web server for reproducible Hi-C data analysis, quality control and visualization.

Wolff J, Bhardwaj V, Nothjunge S, Richard G, Renschler G, Gilsbach R, Manke T, Backofen R, Ramírez F, Grüning BA.

Nucleic Acids Res. 2018 Jul 2;46(W1):W11-W16. doi: 10.1093/nar/gky504.

15.

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update.

Afgan E, Baker D, Batut B, van den Beek M, Bouvier D, Cech M, Chilton J, Clements D, Coraor N, Grüning BA, Guerler A, Hillman-Jackson J, Hiltemann S, Jalili V, Rasche H, Soranzo N, Goecks J, Taylor J, Nekrutenko A, Blankenberg D.

Nucleic Acids Res. 2018 Jul 2;46(W1):W537-W544. doi: 10.1093/nar/gky379.

16.

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo.

Gilsbach R, Schwaderer M, Preissl S, Grüning BA, Kranzhöfer D, Schneider P, Nührenberg TG, Mulero-Navarro S, Weichenhan D, Braun C, Dreßen M, Jacobs AR, Lahm H, Doenst T, Backofen R, Krane M, Gelb BD, Hein L.

Nat Commun. 2018 Jan 26;9(1):391. doi: 10.1038/s41467-017-02762-z.

17.

High-resolution TADs reveal DNA sequences underlying genome organization in flies.

Ramírez F, Bhardwaj V, Arrigoni L, Lam KC, Grüning BA, Villaveces J, Habermann B, Akhtar A, Manke T.

Nat Commun. 2018 Jan 15;9(1):189. doi: 10.1038/s41467-017-02525-w.

18.

Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes.

Thriene K, Grüning BA, Bornert O, Erxleben A, Leppert J, Athanasiou I, Weber E, Kiritsi D, Nyström A, Reinheckel T, Backofen R, Has C, Bruckner-Tuderman L, Dengjel J.

Mol Cell Proteomics. 2018 Apr;17(4):565-579. doi: 10.1074/mcp.RA117.000437. Epub 2018 Jan 11.

19.

DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes.

Nothjunge S, Nührenberg TG, Grüning BA, Doppler SA, Preissl S, Schwaderer M, Rommel C, Krane M, Hein L, Gilsbach R.

Nat Commun. 2017 Nov 21;8(1):1667. doi: 10.1038/s41467-017-01724-9.

20.

An Accessible Proteogenomics Informatics Resource for Cancer Researchers.

Chambers MC, Jagtap PD, Johnson JE, McGowan T, Kumar P, Onsongo G, Guerrero CR, Barsnes H, Vaudel M, Martens L, Grüning B, Cooke IR, Heydarian M, Reddy KL, Griffin TJ.

Cancer Res. 2017 Nov 1;77(21):e43-e46. doi: 10.1158/0008-5472.CAN-17-0331.

21.

EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.

Glaser LV, Rieger S, Thumann S, Beer S, Kuklik-Roos C, Martin DE, Maier KC, Harth-Hertle ML, Grüning B, Backofen R, Krebs S, Blum H, Zimmer R, Erhard F, Kempkes B.

PLoS Pathog. 2017 Oct 2;13(10):e1006664. doi: 10.1371/journal.ppat.1006664. eCollection 2017 Oct.

22.

Strategies for analyzing bisulfite sequencing data.

Wreczycka K, Gosdschan A, Yusuf D, Grüning B, Assenov Y, Akalin A.

J Biotechnol. 2017 Nov 10;261:105-115. doi: 10.1016/j.jbiotec.2017.08.007. Epub 2017 Aug 16. Review.

23.

Four simple recommendations to encourage best practices in research software.

Jiménez RC, Kuzak M, Alhamdoosh M, Barker M, Batut B, Borg M, Capella-Gutierrez S, Chue Hong N, Cook M, Corpas M, Flannery M, Garcia L, Gelpí JL, Gladman S, Goble C, González Ferreiro M, Gonzalez-Beltran A, Griffin PC, Grüning B, Hagberg J, Holub P, Hooft R, Ison J, Katz DS, Leskošek B, López Gómez F, Oliveira LJ, Mellor D, Mosbergen R, Mulder N, Perez-Riverol Y, Pergl R, Pichler H, Pope B, Sanz F, Schneider MV, Stodden V, Suchecki R, Svobodová Vařeková R, Talvik HA, Todorov I, Treloar A, Tyagi S, van Gompel M, Vaughan D, Via A, Wang X, Watson-Haigh NS, Crouch S.

F1000Res. 2017 Jun 13;6. pii: ELIXIR-876. doi: 10.12688/f1000research.11407.1. eCollection 2017.

24.

Recent advances in RNA folding.

Fallmann J, Will S, Engelhardt J, Grüning B, Backofen R, Stadler PF.

J Biotechnol. 2017 Nov 10;261:97-104. doi: 10.1016/j.jbiotec.2017.07.007. Epub 2017 Jul 8. Review.

25.

The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy.

Grüning BA, Fallmann J, Yusuf D, Will S, Erxleben A, Eggenhofer F, Houwaart T, Batut B, Videm P, Bagnacani A, Wolfien M, Lott SC, Hoogstrate Y, Hess WR, Wolkenhauer O, Hoffmann S, Akalin A, Ohler U, Stadler PF, Backofen R.

Nucleic Acids Res. 2017 Jul 3;45(W1):W560-W566. doi: 10.1093/nar/gkx409.

26.

RNA-bioinformatics: Tools, services and databases for the analysis of RNA-based regulation.

Backofen R, Engelhardt J, Erxleben A, Fallmann J, Grüning B, Ohler U, Rajewsky N, Stadler PF.

J Biotechnol. 2017 Nov 10;261:76-84. doi: 10.1016/j.jbiotec.2017.05.019. Epub 2017 May 26. Review.

27.

Jupyter and Galaxy: Easing entry barriers into complex data analyses for biomedical researchers.

Grüning BA, Rasche E, Rebolledo-Jaramillo B, Eberhard C, Houwaart T, Chilton J, Coraor N, Backofen R, Taylor J, Nekrutenko A.

PLoS Comput Biol. 2017 May 25;13(5):e1005425. doi: 10.1371/journal.pcbi.1005425. eCollection 2017 May.

28.

ReGaTE: Registration of Galaxy Tools in Elixir.

Doppelt-Azeroual O, Mareuil F, Deveaud E, Kalaš M, Soranzo N, van den Beek M, Grüning B, Ison J, Ménager H.

Gigascience. 2017 Jun 1;6(6):1-4. doi: 10.1093/gigascience/gix022.

29.

BioContainers: an open-source and community-driven framework for software standardization.

da Veiga Leprevost F, Grüning BA, Alves Aflitos S, Röst HL, Uszkoreit J, Barsnes H, Vaudel M, Moreno P, Gatto L, Weber J, Bai M, Jimenez RC, Sachsenberg T, Pfeuffer J, Vera Alvarez R, Griss J, Nesvizhskii AI, Perez-Riverol Y.

Bioinformatics. 2017 Aug 15;33(16):2580-2582. doi: 10.1093/bioinformatics/btx192.

30.

GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders.

Hornig T, Grüning B, Kundu K, Houwaart T, Backofen R, Biber K, Normann C.

Genet Res (Camb). 2017 Jan 30;99:e1. doi: 10.1017/S0016672316000148.

PMID:
28132660
31.

5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte Maturation.

Kranzhöfer DK, Gilsbach R, Grüning BA, Backofen R, Nührenberg TG, Hein L.

PLoS One. 2016 Nov 16;11(11):e0166575. doi: 10.1371/journal.pone.0166575. eCollection 2016.

32.

PubMedPortable: A Framework for Supporting the Development of Text Mining Applications.

Döring K, Grüning BA, Telukunta KK, Thomas P, Günther S.

PLoS One. 2016 Oct 5;11(10):e0163794. doi: 10.1371/journal.pone.0163794. eCollection 2016.

34.

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update.

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J.

Nucleic Acids Res. 2016 Jul 8;44(W1):W3-W10. doi: 10.1093/nar/gkw343. Epub 2016 May 2.

35.

deepTools2: a next generation web server for deep-sequencing data analysis.

Ramírez F, Ryan DP, Grüning B, Bhardwaj V, Kilpert F, Richter AS, Heyne S, Dündar F, Manke T.

Nucleic Acids Res. 2016 Jul 8;44(W1):W160-5. doi: 10.1093/nar/gkw257. Epub 2016 Apr 13.

36.

MicroRNA Profiling in Aqueous Humor of Individual Human Eyes by Next-Generation Sequencing.

Wecker T, Hoffmeier K, Plötner A, Grüning BA, Horres R, Backofen R, Reinhard T, Schlunck G.

Invest Ophthalmol Vis Sci. 2016 Apr;57(4):1706-13. doi: 10.1167/iovs.15-17828.

PMID:
27064390
37.

Tools and data services registry: a community effort to document bioinformatics resources.

Ison J, Rapacki K, Ménager H, Kalaš M, Rydza E, Chmura P, Anthon C, Beard N, Berka K, Bolser D, Booth T, Bretaudeau A, Brezovsky J, Casadio R, Cesareni G, Coppens F, Cornell M, Cuccuru G, Davidsen K, Vedova GD, Dogan T, Doppelt-Azeroual O, Emery L, Gasteiger E, Gatter T, Goldberg T, Grosjean M, Grüning B, Helmer-Citterich M, Ienasescu H, Ioannidis V, Jespersen MC, Jimenez R, Juty N, Juvan P, Koch M, Laibe C, Li JW, Licata L, Mareuil F, Mičetić I, Friborg RM, Moretti S, Morris C, Möller S, Nenadic A, Peterson H, Profiti G, Rice P, Romano P, Roncaglia P, Saidi R, Schafferhans A, Schwämmle V, Smith C, Sperotto MM, Stockinger H, Vařeková RS, Tosatto SC, de la Torre V, Uva P, Via A, Yachdav G, Zambelli F, Vriend G, Rost B, Parkinson H, Løngreen P, Brunak S.

Nucleic Acids Res. 2016 Jan 4;44(D1):D38-47. doi: 10.1093/nar/gkv1116. Epub 2015 Nov 3.

38.

NCBI BLAST+ integrated into Galaxy.

Cock PJ, Chilton JM, Grüning B, Johnson JE, Soranzo N.

Gigascience. 2015 Aug 25;4:39. doi: 10.1186/s13742-015-0080-7. eCollection 2015.

39.

DOT1L Activity Promotes Proliferation and Protects Cortical Neural Stem Cells from Activation of ATF4-DDIT3-Mediated ER Stress In Vitro.

Roidl D, Hellbach N, Bovio PP, Villarreal A, Heidrich S, Nestel S, Grüning BA, Boenisch U, Vogel T.

Stem Cells. 2016 Jan;34(1):233-45. doi: 10.1002/stem.2187. Epub 2015 Sep 29.

40.

Anatomy of BioJS, an open source community for the life sciences.

Yachdav G, Goldberg T, Wilzbach S, Dao D, Shih I, Choudhary S, Crouch S, Franz M, García A, García LJ, Grüning BA, Inupakutika D, Sillitoe I, Thanki AS, Vieira B, Villaveces JM, Schneider MV, Lewis S, Pettifer S, Rost B, Corpas M.

Elife. 2015 Jul 8;4. doi: 10.7554/eLife.07009.

41.

Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.

Preissl S, Schwaderer M, Raulf A, Hesse M, Grüning BA, Köbele C, Backofen R, Fleischmann BK, Hein L, Gilsbach R.

Circ Res. 2015 Aug 14;117(5):413-23. doi: 10.1161/CIRCRESAHA.115.306337. Epub 2015 Jun 23.

PMID:
26105955
42.

The purchasable chemical space: a detailed picture.

Lucas X, Grüning BA, Bleher S, Günther S.

J Chem Inf Model. 2015 May 26;55(5):915-24. doi: 10.1021/acs.jcim.5b00116. Epub 2015 Apr 30.

PMID:
25894297
43.

An NGS Workflow Blueprint for DNA Sequencing Data and Its Application in Individualized Molecular Oncology.

Li J, Batcha AM, Grüning B, Mansmann UR.

Cancer Inform. 2016 Apr 10;14(Suppl 5):87-107. doi: 10.4137/CIN.S30793. eCollection 2015. Review.

44.

Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.

Gilsbach R, Preissl S, Grüning BA, Schnick T, Burger L, Benes V, Würch A, Bönisch U, Günther S, Backofen R, Fleischmann BK, Schübeler D, Hein L.

Nat Commun. 2014 Oct 22;5:5288. doi: 10.1038/ncomms6288.

45.

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

Schubert D, Bode C, Kenefeck R, Hou TZ, Wing JB, Kennedy A, Bulashevska A, Petersen BS, Schäffer AA, Grüning BA, Unger S, Frede N, Baumann U, Witte T, Schmidt RE, Dueckers G, Niehues T, Seneviratne S, Kanariou M, Speckmann C, Ehl S, Rensing-Ehl A, Warnatz K, Rakhmanov M, Thimme R, Hasselblatt P, Emmerich F, Cathomen T, Backofen R, Fisch P, Seidl M, May A, Schmitt-Graeff A, Ikemizu S, Salzer U, Franke A, Sakaguchi S, Walker LSK, Sansom DM, Grimbacher B.

Nat Med. 2014 Dec;20(12):1410-1416. doi: 10.1038/nm.3746. Epub 2014 Oct 20.

46.

PyWATER: a PyMOL plug-in to find conserved water molecules in proteins by clustering.

Patel H, Grüning BA, Günther S, Merfort I.

Bioinformatics. 2014 Oct 15;30(20):2978-80. doi: 10.1093/bioinformatics/btu424. Epub 2014 Jul 1.

PMID:
24990608
47.

deepTools: a flexible platform for exploring deep-sequencing data.

Ramírez F, Dündar F, Diehl S, Grüning BA, Manke T.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W187-91. doi: 10.1093/nar/gku365. Epub 2014 May 5.

48.

Regio- and stereoselective intermolecular oxidative phenol coupling in Streptomyces.

Präg A, Grüning BA, Häckh M, Lüdeke S, Wilde M, Luzhetskyy A, Richter M, Luzhetska M, Günther S, Müller M.

J Am Chem Soc. 2014 Apr 30;136(17):6195-8. doi: 10.1021/ja501630w. Epub 2014 Apr 18.

PMID:
24746278
49.

Galaxy tools and workflows for sequence analysis with applications in molecular plant pathology.

Cock PJ, Grüning BA, Paszkiewicz K, Pritchard L.

PeerJ. 2013 Sep 17;1:e167. doi: 10.7717/peerj.167. eCollection 2013.

50.

Characterization and phylogenetic analysis of the mitochondrial genome of Glarea lozoyensis indicates high diversity within the order Helotiales.

Youssar L, Grüning BA, Günther S, Hüttel W.

PLoS One. 2013 Sep 25;8(9):e74792. doi: 10.1371/journal.pone.0074792. eCollection 2013.

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