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Structure of human TFIID and mechanism of TBP loading onto promoter DNA.

Patel AB, Louder RK, Greber BJ, Grünberg S, Luo J, Fang J, Liu Y, Ranish J, Hahn S, Nogales E.

Science. 2018 Dec 21;362(6421). pii: eaau8872. doi: 10.1126/science.aau8872. Epub 2018 Nov 15.


Distinct patterns of histone acetyltransferase and Mediator deployment at yeast protein-coding genes.

Bruzzone MJ, Grünberg S, Kubik S, Zentner GE, Shore D.

Genes Dev. 2018 Sep 1;32(17-18):1252-1265. doi: 10.1101/gad.312173.118. Epub 2018 Aug 14.


SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Baptista T, Grünberg S, Minoungou N, Koster MJE, Timmers HTM, Hahn S, Devys D, Tora L.

Mol Cell. 2018 Jun 21;70(6):1163-1164. doi: 10.1016/j.molcel.2018.06.007. No abstract available.


SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Baptista T, Grünberg S, Minoungou N, Koster MJE, Timmers HTM, Hahn S, Devys D, Tora L.

Mol Cell. 2017 Oct 5;68(1):130-143.e5. doi: 10.1016/j.molcel.2017.08.016. Epub 2017 Sep 14. Erratum in: Mol Cell. 2018 Jun 21;70(6):1163-1164.


Genome-wide Mapping of Protein-DNA Interactions with ChEC-seq in Saccharomyces cerevisiae.

Grünberg S, Zentner GE.

J Vis Exp. 2017 Jun 3;(124). doi: 10.3791/55836.


Genome-wide characterization of Mediator recruitment, function, and regulation.

Grünberg S, Zentner GE.

Transcription. 2017 May 27;8(3):169-174. doi: 10.1080/21541264.2017.1291082. Epub 2017 Feb 8. Review.


Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters.

Grünberg S, Henikoff S, Hahn S, Zentner GE.

EMBO J. 2016 Nov 15;35(22):2435-2446. Epub 2016 Oct 20.


Double-Blind Phase III Randomized Trial of the Antiprogestin Agent Mifepristone in the Treatment of Unresectable Meningioma: SWOG S9005.

Ji Y, Rankin C, Grunberg S, Sherrod AE, Ahmadi J, Townsend JJ, Feun LG, Fredericks RK, Russell CA, Kabbinavar FF, Stelzer KJ, Schott A, Verschraegen C.

J Clin Oncol. 2015 Dec 1;33(34):4093-8. doi: 10.1200/JCO.2015.61.6490. Epub 2015 Nov 2.


Alterations of the Subgingival Microbiota in Pediatric Crohn's Disease Studied Longitudinally in Discovery and Validation Cohorts.

Kelsen J, Bittinger K, Pauly-Hubbard H, Posivak L, Grunberg S, Baldassano R, Lewis JD, Wu GD, Bushman FD.

Inflamm Bowel Dis. 2015 Dec;21(12):2797-805. doi: 10.1097/MIB.0000000000000557.


Fungal Signature in the Gut Microbiota of Pediatric Patients With Inflammatory Bowel Disease.

Chehoud C, Albenberg LG, Judge C, Hoffmann C, Grunberg S, Bittinger K, Baldassano RN, Lewis JD, Bushman FD, Wu GD.

Inflamm Bowel Dis. 2015 Aug;21(8):1948-56. doi: 10.1097/MIB.0000000000000454.


Efficacy and safety of oral palonosetron compared with IV palonosetron administered with dexamethasone for the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients with solid tumors receiving cisplatin-based highly emetogenic chemotherapy (HEC).

Karthaus M, Tibor C, Lorusso V, Singh-Arora R, Filippov A, Rizzi G, Borroni ME, Rossi G, Grunberg SM.

Support Care Cancer. 2015 Oct;23(10):2917-23. doi: 10.1007/s00520-015-2657-1. Epub 2015 Feb 28.


Unanticipated frequency and consequences of regimen-related diarrhea in patients being treated with radiation or chemoradiation regimens for cancers of the head and neck or lung.

Sonis S, Elting L, Keefe D, Nguyen H, Grunberg S, Randolph-Jackson P, Brennan M; TRIAD Burden of Illness Investigators.

Support Care Cancer. 2015 Feb;23(2):433-9. doi: 10.1007/s00520-014-2395-9. Epub 2014 Aug 16.


Risk and outcomes of chemotherapy-induced diarrhea (CID) among patients with colorectal cancer receiving multi-cycle chemotherapy.

Keefe DM, Elting LS, Nguyen HT, Grunberg SM, Aprile G, Bonaventura A, Selva-Nayagam S, Barsevick A, Koczwara B, Sonis ST.

Cancer Chemother Pharmacol. 2014 Oct;74(4):675-80. doi: 10.1007/s00280-014-2526-5. Epub 2014 Jul 25.


Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota.

Albenberg L, Esipova TV, Judge CP, Bittinger K, Chen J, Laughlin A, Grunberg S, Baldassano RN, Lewis JD, Li H, Thom SR, Bushman FD, Vinogradov SA, Wu GD.

Gastroenterology. 2014 Nov;147(5):1055-63.e8. doi: 10.1053/j.gastro.2014.07.020. Epub 2014 Jul 18.


A randomized phase III study evaluating the efficacy and safety of NEPA, a fixed-dose combination of netupitant and palonosetron, for prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy.

Aapro M, Rugo H, Rossi G, Rizzi G, Borroni ME, Bondarenko I, Sarosiek T, Oprean C, Cardona-Huerta S, Lorusso V, Karthaus M, Schwartzberg L, Grunberg S.

Ann Oncol. 2014 Jul;25(7):1328-33. doi: 10.1093/annonc/mdu101. Epub 2014 Mar 5.


Early recognition of malnutrition and cachexia in the cancer patient: a position paper of a European School of Oncology Task Force.

Aapro M, Arends J, Bozzetti F, Fearon K, Grunberg SM, Herrstedt J, Hopkinson J, Jacquelin-Ravel N, Jatoi A, Kaasa S, Strasser F; ESMO (European School of Medical Oncology).

Ann Oncol. 2014 Aug;25(8):1492-9. doi: 10.1093/annonc/mdu085. Epub 2014 Feb 25. Review.


Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.

Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CG, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M, Snyder A, Giacomin PR, Joyce KL, Hoang TB, Bewtra M, Brodsky IE, Sonnenberg GF, Bushman FD, Won KJ, Lazar MA, Artis D.

Nature. 2013 Dec 5;504(7478):153-7. doi: 10.1038/nature12687. Epub 2013 Nov 3.


Structural insights into transcription initiation by RNA polymerase II.

Grünberg S, Hahn S.

Trends Biochem Sci. 2013 Dec;38(12):603-11. doi: 10.1016/j.tibs.2013.09.002. Epub 2013 Oct 11. Review.


Supportive care during treatment for breast cancer: resource allocations in low- and middle-income countries. A Breast Health Global Initiative 2013 consensus statement.

Cardoso F, Bese N, Distelhorst SR, Bevilacqua JL, Ginsburg O, Grunberg SM, Gralla RJ, Steyn A, Pagani O, Partridge AH, Knaul FM, Aapro MS, Andersen BL, Thompson B, Gralow JR, Anderson BO.

Breast. 2013 Oct;22(5):593-605. doi: 10.1016/j.breast.2013.07.050. Epub 2013 Aug 31. Review.


Fungi of the murine gut: episodic variation and proliferation during antibiotic treatment.

Dollive S, Chen YY, Grunberg S, Bittinger K, Hoffmann C, Vandivier L, Cuff C, Lewis JD, Wu GD, Bushman FD.

PLoS One. 2013 Aug 19;8(8):e71806. doi: 10.1371/journal.pone.0071806. eCollection 2013.


Archaea and fungi of the human gut microbiome: correlations with diet and bacterial residents.

Hoffmann C, Dollive S, Grunberg S, Chen J, Li H, Wu GD, Lewis JD, Bushman FD.

PLoS One. 2013 Jun 17;8(6):e66019. doi: 10.1371/journal.pone.0066019. Print 2013.


Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria.

Hepworth MR, Monticelli LA, Fung TC, Ziegler CG, Grunberg S, Sinha R, Mantegazza AR, Ma HL, Crawford A, Angelosanto JM, Wherry EJ, Koni PA, Bushman FD, Elson CO, Eberl G, Artis D, Sonnenberg GF.

Nature. 2013 Jun 6;498(7452):113-7. doi: 10.1038/nature12240. Epub 2013 May 22.


Emerging treatments in chemotherapy-induced nausea and vomiting.

Grunberg SM, Slusher B, Rugo HS.

Clin Adv Hematol Oncol. 2013 Feb;11(2 Suppl 1):1-18; quiz 2 p following 18. Review.


Molecular mechanisms underlying skeletal muscle weakness in human cancer: reduced myosin-actin cross-bridge formation and kinetics.

Toth MJ, Miller MS, Callahan DM, Sweeny AP, Nunez I, Grunberg SM, Der-Torossian H, Couch ME, Dittus K.

J Appl Physiol (1985). 2013 Apr;114(7):858-68. doi: 10.1152/japplphysiol.01474.2012. Epub 2013 Feb 14.


Efficacy of oral palonosetron compared to intravenous palonosetron for the prevention of chemotherapy-induced nausea and vomiting associated with moderately emetogenic chemotherapy: a phase 3 trial.

Boccia R, Grunberg S, Franco-Gonzales E, Rubenstein E, Voisin D.

Support Care Cancer. 2013 May;21(5):1453-60. doi: 10.1007/s00520-012-1691-5. Epub 2013 Jan 26.


A tool kit for quantifying eukaryotic rRNA gene sequences from human microbiome samples.

Dollive S, Peterfreund GL, Sherrill-Mix S, Bittinger K, Sinha R, Hoffmann C, Nabel CS, Hill DA, Artis D, Bachman MA, Custers-Allen R, Grunberg S, Wu GD, Lewis JD, Bushman FD.

Genome Biol. 2012 Jul 3;13(7):R60. doi: 10.1186/gb-2012-13-7-r60.


Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening.

Grünberg S, Warfield L, Hahn S.

Nat Struct Mol Biol. 2012 Aug;19(8):788-96. doi: 10.1038/nsmb.2334. Epub 2012 Jul 1.


Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

Sonnenberg GF, Monticelli LA, Alenghat T, Fung TC, Hutnick NA, Kunisawa J, Shibata N, Grunberg S, Sinha R, Zahm AM, Tardif MR, Sathaliyawala T, Kubota M, Farber DL, Collman RG, Shaked A, Fouser LA, Weiner DB, Tessier PA, Friedman JR, Kiyono H, Bushman FD, Chang KM, Artis D.

Science. 2012 Jun 8;336(6086):1321-5. doi: 10.1126/science.1222551. Epub 2012 Jun 6.


Patient-centered management of chemotherapy-induced nausea and vomiting.

Grunberg S.

Cancer Control. 2012 Apr;19(2 Suppl):10-5. Review.


Improving control of chemotherapy-induced nausea and vomiting.

Grunberg S.

Cancer Control. 2012 Apr;19(2 Suppl):2. No abstract available.


Recent advances and updated guidelines in the management of chemotherapy-induced nausea and vomiting.

Schwartzberg LS, Grunberg SM, Kris MG.

Clin Adv Hematol Oncol. 2011 Nov;9(11 Suppl 27):1-14; quiz 15-6.


Hypervariable loci in the human gut virome.

Minot S, Grunberg S, Wu GD, Lewis JD, Bushman FD.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3962-6. doi: 10.1073/pnas.1119061109. Epub 2012 Feb 21.


Communicating about chemotherapy-induced nausea and vomiting: a comparison of patient and provider perspectives.

Salsman JM, Grunberg SM, Beaumont JL, Rogers M, Paul D, Clayman ML, Cella D.

J Natl Compr Canc Netw. 2012 Feb;10(2):149-57.


Chemotherapy-induced nausea and vomiting incidence and prevalence.

Grunberg SM.

Am Soc Clin Oncol Educ Book. 2012:541-3. doi: 10.14694/EdBook_AM.2012.32.541.


Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with cisplatin therapy: randomized, double-blind study protocol--EASE.

Grunberg S, Chua D, Maru A, Dinis J, DeVandry S, Boice JA, Hardwick JS, Beckford E, Taylor A, Carides A, Roila F, Herrstedt J.

J Clin Oncol. 2011 Apr 10;29(11):1495-501. doi: 10.1200/JCO.2010.31.7859. Epub 2011 Mar 7.


Cost-utility analysis of palonosetron-based therapy in preventing emesis among breast cancer patients.

Avritscher EB, Shih YC, Sun CC, Gralla RJ, Grunberg SM, Xu Y, Elting LS.

J Support Oncol. 2010 Nov-Dec;8(6):242-51.


Antiemetic research: future directions.

Olver I, Molassiotis A, Aapro M, Herrstedt J, Grunberg S, Morrow G.

Support Care Cancer. 2011 Mar;19 Suppl 1:S49-55. doi: 10.1007/s00520-010-1036-1. Epub 2010 Nov 10.


Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity--state of the art.

Grunberg SM, Warr D, Gralla RJ, Rapoport BL, Hesketh PJ, Jordan K, Espersen BT.

Support Care Cancer. 2011 Mar;19 Suppl 1:S43-7. doi: 10.1007/s00520-010-1003-x. Epub 2010 Oct 24. Review.


Efficacy and tolerability of transdermal granisetron for the control of chemotherapy-induced nausea and vomiting associated with moderately and highly emetogenic multi-day chemotherapy: a randomized, double-blind, phase III study.

Boccia RV, Gordan LN, Clark G, Howell JD, Grunberg SM; Sancuso Study Group.

Support Care Cancer. 2011 Oct;19(10):1609-17. doi: 10.1007/s00520-010-0990-y. Epub 2010 Sep 12.


Consensus recommendations for the prevention of vomiting and nausea following high-emetic-risk chemotherapy.

Kris MG, Tonato M, Bria E, Ballatori E, Espersen B, Herrstedt J, Rittenberg C, Einhorn LH, Grunberg S, Saito M, Morrow G, Hesketh P.

Support Care Cancer. 2011 Mar;19 Suppl 1:S25-32. doi: 10.1007/s00520-010-0976-9. Epub 2010 Aug 28.


Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the Perugia consensus conference.

Roila F, Herrstedt J, Aapro M, Gralla RJ, Einhorn LH, Ballatori E, Bria E, Clark-Snow RA, Espersen BT, Feyer P, Grunberg SM, Hesketh PJ, Jordan K, Kris MG, Maranzano E, Molassiotis A, Morrow G, Olver I, Rapoport BL, Rittenberg C, Saito M, Tonato M, Warr D; ESMO/MASCC Guidelines Working Group.

Ann Oncol. 2010 May;21 Suppl 5:v232-43. doi: 10.1093/annonc/mdq194. Review. No abstract available.


Antiemetic therapy for multiple-day chemotherapy and additional topics consisting of rescue antiemetics and high-dose chemotherapy with stem cell transplant: review and consensus statement.

Einhorn LH, Grunberg SM, Rapoport B, Rittenberg C, Feyer P.

Support Care Cancer. 2011 Mar;19 Suppl 1:S1-4. doi: 10.1007/s00520-010-0920-z. Epub 2010 May 26.


Chemotherapy-induced nausea and vomiting: contemporary approaches to optimal management. Proceedings from a symposium at the 2008 Multinational Association of Supportive Care in Cancer (MASCC) Annual Meeting.

Grunberg S, Clark-Snow RA, Koeller J.

Support Care Cancer. 2010 Mar;18 Suppl 1:S1-10. doi: 10.1007/s00520-009-0807-z. Epub 2010 Jan 19.


Rearrangement of the RNA polymerase subunit H and the lower jaw in archaeal elongation complexes.

Grünberg S, Reich C, Zeller ME, Bartlett MS, Thomm M.

Nucleic Acids Res. 2010 Apr;38(6):1950-63. doi: 10.1093/nar/gkp1190. Epub 2009 Dec 29.


Phase III trial of casopitant, a novel neurokinin-1 receptor antagonist, for the prevention of nausea and vomiting in patients receiving moderately emetogenic chemotherapy.

Herrstedt J, Apornwirat W, Shaharyar A, Aziz Z, Roila F, Van Belle S, Russo MW, Levin J, Ranganathan S, Guckert M, Grunberg SM.

J Clin Oncol. 2009 Nov 10;27(32):5363-9. doi: 10.1200/JCO.2009.21.8511. Epub 2009 Oct 5.


Protocol for the examination of specimens from patients with primary non-small cell carcinoma, small cell carcinoma, or carcinoid tumor of the lung.

Butnor KJ, Beasley MB, Cagle PT, Grunberg SM, Kong FM, Marchevsky A, Okby NT, Roggli VL, Suster S, Tazelaar HD, Travis WD; Members of the Cancer Committee, College of American Pathologists.

Arch Pathol Lab Med. 2009 Oct;133(10):1552-9. doi: 10.1043/1543-2165-133.10.1552. No abstract available.


Randomized, double-blind, dose-ranging trial of the oral neurokinin-1 receptor antagonist casopitant mesylate for the prevention of cisplatin-induced nausea and vomiting.

Roila F, Rolski J, Ramlau R, Dediu M, Russo MW, Bandekar RR, Grunberg SM.

Ann Oncol. 2009 Nov;20(11):1867-73. doi: 10.1093/annonc/mdp194. Epub 2009 Jun 18.


Obstacles to the implementation of antiemetic guidelines.

Grunberg SM.

J Natl Compr Canc Netw. 2009 May;7(5):601-5.


Efficacy and safety of casopitant mesylate, a neurokinin 1 (NK1)-receptor antagonist, in prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based highly emetogenic chemotherapy: a randomised, double-blind, placebo-controlled trial.

Grunberg SM, Rolski J, Strausz J, Aziz Z, Lane S, Russo MW, Wissel P, Guckert M, Wright O, Herrstedt J.

Lancet Oncol. 2009 Jun;10(6):549-58. doi: 10.1016/S1470-2045(09)70109-3. Epub 2009 May 8.


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