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Items: 48

1.

Mapping the physical network of cellular interactions.

Boisset JC, Vivié J, Grün D, Muraro MJ, Lyubimova A, van Oudenaarden A.

Nat Methods. 2018 Jul;15(7):547-553. doi: 10.1038/s41592-018-0009-z. Epub 2018 May 21.

PMID:
29786092
2.

NRP-1 interacts with GIPC1 and α6/β4-integrins to increase YAP1/∆Np63α-dependent epidermal cancer stem cell survival.

Grun D, Adhikary G, Eckert RL.

Oncogene. 2018 May 14. doi: 10.1038/s41388-018-0290-4. [Epub ahead of print]

PMID:
29755126
3.

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.

Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA.

Cell Metab. 2018 Jun 5;27(6):1294-1308.e7. doi: 10.1016/j.cmet.2018.04.013. Epub 2018 May 10.

4.

FateID infers cell fate bias in multipotent progenitors from single-cell RNA-seq data.

Herman JS, Sagar, Grün D.

Nat Methods. 2018 May;15(5):379-386. doi: 10.1038/nmeth.4662. Epub 2018 Apr 9.

PMID:
29630061
5.

High-Throughput Single-Cell RNA Sequencing and Data Analysis.

Sagar, Herman JS, Pospisilik JA, Grün D.

Methods Mol Biol. 2018;1766:257-283. doi: 10.1007/978-1-4939-7768-0_15.

PMID:
29605858
6.

[Severe caffeine poisoning with rhabdomyolysis].

Wolter J, Grün D, Otto S.

Anaesthesist. 2018 Apr;67(4):270-274. doi: 10.1007/s00101-018-0414-9. Epub 2018 Feb 21. German.

PMID:
29468414
7.

Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells.

Fisher ML, Grun D, Adhikary G, Xu W, Eckert RL.

Oncotarget. 2017 Nov 22;8(66):110257-110272. doi: 10.18632/oncotarget.22628. eCollection 2017 Dec 15.

8.

Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation.

Fisher ML, Ciavattone N, Grun D, Adhikary G, Eckert RL.

Oncotarget. 2017 Aug 27;8(43):73407-73418. doi: 10.18632/oncotarget.20562. eCollection 2017 Sep 26.

9.

Zooming in on liver zonation.

Felmlee DJ, Grün D, Baumert TF.

Hepatology. 2017 Sep 27. doi: 10.1002/hep.29554. [Epub ahead of print] No abstract available.

PMID:
28960459
10.

Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.

Saha K, Fisher ML, Adhikary G, Grun D, Eckert RL.

Carcinogenesis. 2017 Aug 1;38(8):827-836. doi: 10.1093/carcin/bgx044.

PMID:
28854561
11.

Transglutaminase 2 Is a Direct Target Gene of YAP-TAZ-Response.

Fisher ML, Adhikary G, Kerr C, Grun D, Eckert RL.

Cancer Res. 2017 Sep 1;77(17):4736. doi: 10.1158/0008-5472.CAN-17-1255. Epub 2017 Aug 15. No abstract available. Erratum in: Cancer Res. 2018 May 15;78(10 ):2775.

PMID:
28811329
12.

Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma.

Kerr C, Adhikary G, Grun D, George N, Eckert RL.

Mol Carcinog. 2018 Jan;57(1):3-11. doi: 10.1002/mc.22714. Epub 2017 Aug 28.

PMID:
28796401
13.

A new fate mapping system reveals context-dependent random or clonal expansion of microglia.

Tay TL, Mai D, Dautzenberg J, Fernández-Klett F, Lin G, Sagar, Datta M, Drougard A, Stempfl T, Ardura-Fabregat A, Staszewski O, Margineanu A, Sporbert A, Steinmetz LM, Pospisilik JA, Jung S, Priller J, Grün D, Ronneberger O, Prinz M.

Nat Neurosci. 2017 Jun;20(6):793-803. doi: 10.1038/nn.4547. Epub 2017 Apr 17.

PMID:
28414331
14.

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A.

Cell. 2016 Nov 17;167(5):1264-1280.e18. doi: 10.1016/j.cell.2016.09.054. Epub 2016 Oct 27.

15.

A Single-Cell Transcriptome Atlas of the Human Pancreas.

Muraro MJ, Dharmadhikari G, Grün D, Groen N, Dielen T, Jansen E, van Gurp L, Engelse MA, Carlotti F, de Koning EJ, van Oudenaarden A.

Cell Syst. 2016 Oct 26;3(4):385-394.e3. doi: 10.1016/j.cels.2016.09.002. Epub 2016 Sep 29.

16.

Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor Formation.

Fisher ML, Kerr C, Adhikary G, Grun D, Xu W, Keillor JW, Eckert RL.

Cancer Res. 2016 Dec 15;76(24):7265-7276. Epub 2016 Oct 25.

17.

Response to Letter of the Editor by Tomoyuki Kawada Regarding the Article "Contributory Factors to Caregiver Burden in Parkinson Disease" by Grün et al.

Grün D, Vaillant M, Pieri V, Diederich NJ.

J Am Med Dir Assoc. 2016 Nov 1;17(11):1060-1061. doi: 10.1016/j.jamda.2016.08.011. No abstract available.

PMID:
27780568
18.

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data.

Grün D, Muraro MJ, Boisset JC, Wiebrands K, Lyubimova A, Dharmadhikari G, van den Born M, van Es J, Jansen E, Clevers H, de Koning EJP, van Oudenaarden A.

Cell Stem Cell. 2016 Aug 4;19(2):266-277. doi: 10.1016/j.stem.2016.05.010. Epub 2016 Jun 23.

19.

Contributory Factors to Caregiver Burden in Parkinson Disease.

Grün D, Pieri V, Vaillant M, Diederich NJ.

J Am Med Dir Assoc. 2016 Jul 1;17(7):626-32. doi: 10.1016/j.jamda.2016.03.004. Epub 2016 Apr 30.

20.

Progression-free survival as surrogate end point for overall survival in clinical trials of HER2-targeted agents in HER2-positive metastatic breast cancer.

Michiels S, Pugliano L, Marguet S, Grun D, Barinoff J, Cameron D, Cobleigh M, Di Leo A, Johnston S, Gasparini G, Kaufman B, Marty M, Nekljudova V, Paluch-Shimon S, Penault-Llorca F, Slamon D, Vogel C, von Minckwitz G, Buyse M, Piccart M.

Ann Oncol. 2016 Jun;27(6):1029-34. doi: 10.1093/annonc/mdw132. Epub 2016 Mar 8.

PMID:
26961151
21.

VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors.

Grun D, Adhikary G, Eckert RL.

Oncogene. 2016 Aug 18;35(33):4379-87. doi: 10.1038/onc.2015.507. Epub 2016 Jan 25.

22.

Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration.

Wu CC, Kruse F, Vasudevarao MD, Junker JP, Zebrowski DC, Fischer K, Noël ES, Grün D, Berezikov E, Engel FB, van Oudenaarden A, Weidinger G, Bakkers J.

Dev Cell. 2016 Jan 11;36(1):36-49. doi: 10.1016/j.devcel.2015.12.010. Epub 2015 Dec 31.

23.

The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane.

Fisher ML, Adhikary G, Grun D, Kaetzel DM, Eckert RL.

Mol Carcinog. 2016 Dec;55(12):2024-2036. doi: 10.1002/mc.22448. Epub 2015 Dec 23. Erratum in: Mol Carcinog. 2017 Dec;56(12 ):2718-2720.

24.

Design and Analysis of Single-Cell Sequencing Experiments.

Grün D, van Oudenaarden A.

Cell. 2015 Nov 5;163(4):799-810. doi: 10.1016/j.cell.2015.10.039. Review.

25.

Single-cell messenger RNA sequencing reveals rare intestinal cell types.

Grün D, Lyubimova A, Kester L, Wiebrands K, Basak O, Sasaki N, Clevers H, van Oudenaarden A.

Nature. 2015 Sep 10;525(7568):251-5. doi: 10.1038/nature14966. Epub 2015 Aug 19.

PMID:
26287467
26.

Transglutaminase is a tumor cell and cancer stem cell survival factor.

Eckert RL, Fisher ML, Grun D, Adhikary G, Xu W, Kerr C.

Mol Carcinog. 2015 Oct;54(10):947-58. doi: 10.1002/mc.22375. Epub 2015 Aug 10. Review.

27.

Survival of skin cancer stem cells requires the Ezh2 polycomb group protein.

Adhikary G, Grun D, Balasubramanian S, Kerr C, Huang JM, Eckert RL.

Carcinogenesis. 2015 Jul;36(7):800-10. doi: 10.1093/carcin/bgv064. Epub 2015 May 12.

28.

Global characterization of the oocyte-to-embryo transition in Caenorhabditis elegans uncovers a novel mRNA clearance mechanism.

Stoeckius M, Grün D, Kirchner M, Ayoub S, Torti F, Piano F, Herzog M, Selbach M, Rajewsky N.

EMBO J. 2014 Aug 18;33(16):1751-66. doi: 10.15252/embj.201488769. Epub 2014 Jun 23.

29.

Paternal RNA contributions in the Caenorhabditis elegans zygote.

Stoeckius M, Grün D, Rajewsky N.

EMBO J. 2014 Aug 18;33(16):1740-50. doi: 10.15252/embj.201488117. Epub 2014 Jun 3.

30.

Validation of noise models for single-cell transcriptomics.

Grün D, Kester L, van Oudenaarden A.

Nat Methods. 2014 Jun;11(6):637-40. doi: 10.1038/nmeth.2930. Epub 2014 Apr 20.

PMID:
24747814
31.

Three-dimensional Nuclear Telomere Organization in Multiple Myeloma.

Klewes L, Vallente R, Dupas E, Brand C, Grün D, Guffei A, Sathitruangsak C, Awe JA, Kuzyk A, Lichtensztejn D, Tammur P, Ilus T, Tamm A, Punab M, Rubinger M, Olujohungbe A, Mai S.

Transl Oncol. 2013 Dec 1;6(6):749-56. eCollection 2013 Dec 1.

32.

Conservation of mRNA and protein expression during development of C. elegans.

Grün D, Kirchner M, Thierfelder N, Stoeckius M, Selbach M, Rajewsky N.

Cell Rep. 2014 Feb 13;6(3):565-77. doi: 10.1016/j.celrep.2014.01.001. Epub 2014 Jan 23.

33.

Pericentrosomal localization of the TIG3 tumor suppressor requires an N-terminal hydrophilic region motif.

Scharadin TM, Adhikary G, Shaw K, Grun DJB, Xu W, Eckert RL.

J Invest Dermatol. 2014 May;134(5):1220-1229. doi: 10.1038/jid.2013.533. Epub 2013 Dec 13.

34.

Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation.

Adhikary G, Grun D, Kerr C, Balasubramanian S, Rorke EA, Vemuri M, Boucher S, Bickenbach JR, Hornyak T, Xu W, Fisher ML, Eckert RL.

PLoS One. 2013 Dec 20;8(12):e84324. doi: 10.1371/journal.pone.0084324. eCollection 2013.

35.

Dampening of expression oscillations by synchronous regulation of a microRNA and its target.

Kim Dh, Grün D, van Oudenaarden A.

Nat Genet. 2013 Nov;45(11):1337-44. doi: 10.1038/ng.2763. Epub 2013 Sep 15.

36.

Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.

Onal P, Grün D, Adamidi C, Rybak A, Solana J, Mastrobuoni G, Wang Y, Rahn HP, Chen W, Kempa S, Ziebold U, Rajewsky N.

EMBO J. 2012 Jun 13;31(12):2755-69. doi: 10.1038/emboj.2012.110. Epub 2012 Apr 27.

37.

In vivo and transcriptome-wide identification of RNA binding protein target sites.

Jungkamp AC, Stoeckius M, Mecenas D, Grün D, Mastrobuoni G, Kempa S, Rajewsky N.

Mol Cell. 2011 Dec 9;44(5):828-40. doi: 10.1016/j.molcel.2011.11.009.

38.

A genome-wide map of conserved microRNA targets in C. elegans.

Lall S, Grün D, Krek A, Chen K, Wang YL, Dewey CN, Sood P, Colombo T, Bray N, Macmenamin P, Kao HL, Gunsalus KC, Pachter L, Piano F, Rajewsky N.

Curr Biol. 2006 Mar 7;16(5):460-71. Epub 2006 Feb 2.

39.

microRNA target predictions across seven Drosophila species and comparison to mammalian targets.

Grün D, Wang YL, Langenberger D, Gunsalus KC, Rajewsky N.

PLoS Comput Biol. 2005 Jun;1(1):e13. Epub 2005 Jun 24.

40.

Combinatorial microRNA target predictions.

Krek A, Grün D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, da Piedade I, Gunsalus KC, Stoffel M, Rajewsky N.

Nat Genet. 2005 May;37(5):495-500. Epub 2005 Apr 3.

PMID:
15806104
41.

Reconstruction of the ossicular chain with titanium implants.

Dalchow CV, Grün D, Stupp HF.

Otolaryngol Head Neck Surg. 2001 Dec;125(6):628-30.

PMID:
11743465
42.

[Three years of experience with titanium implants in the middle ear].

Stupp CH, Dalchow C, Grün D, Stupp HF, Wustrow J.

Laryngorhinootologie. 1999 Jun;78(6):299-303. German.

PMID:
10439346
43.

[Replacement of ear ossicles with titanium prostheses].

Stupp CH, Stupp HF, Grün D.

Laryngorhinootologie. 1996 Jun;75(6):335-7. German.

PMID:
8766379
44.

[Simultaneous cisplatin and radiotherapy of locally advanced squamous cell carcinomas of the head and neck region. A clinical pilot study].

Higi M, Heuser L, Schmidt C, Grün D, Schettler D, Schmitt G.

Dtsch Med Wochenschr. 1983 Nov 18;108(46):1743-5. German.

PMID:
6685616
45.

The effect of carbocromen and dipyridamole on blood flow of the gastrocnemius of the dog.

Hirche H, Grün D, Grün G, Langohr HD, Wacker U.

Arzneimittelforschung. 1974 Nov;24(11):1762-9. No abstract available.

PMID:
4480046
46.

Utilization of carbohydrates and free fatty acids by the gastrocnemius of the dog during long lasting rhythmical exercise.

Hirche H, Grün D, Waller W.

Pflugers Arch. 1970;321(2):121-32. No abstract available.

PMID:
5529535
47.

The resistance to blood flow in the gastrocnemius of the dog during sustained and rhythmical isometric and isotonic contractions.

Hirche H, Raff WK, Grün D.

Pflugers Arch. 1970;314(2):97-112. No abstract available.

PMID:
5460737
48.

[Work capacity and glycogen content of skeletal muscle].

Hirche H, Biebrach M, Grün D, Müller-Ruchholtz ER, Waller W.

Pflugers Arch. 1969;312(1):R95-6. German. No abstract available.

PMID:
5390316

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