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Best matches for Grøtli M[au]:

Network analyses identify liver-specific targets for treating liver diseases. Lee S et al. Mol Syst Biol. (2017)

Improving the economics of NASH/NAFLD treatment through the use of systems biology. Bosley J et al. Drug Discov Today. (2017)

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases. Valencia-Sánchez MI et al. J Biol Chem. (2016)

Search results

Items: 1 to 50 of 71

1.

Pulse-shaped two-photon excitation of a fluorescent base analogue approaches single-molecule sensitivity.

Fisher RS, Nobis D, Füchtbauer AF, Bood M, Grøtli M, Wilhelmsson LM, Jones AC, Magennis SW.

Phys Chem Chem Phys. 2018 Nov 9. doi: 10.1039/c8cp05496g. [Epub ahead of print]

PMID:
30412214
2.

Shining New Light on the Spiropyran Photoswitch: A Photocage Decides between cis- trans or Spiro-Merocyanine Isomerization.

Fleming CL, Li S, Grøtli M, Andréasson J.

J Am Chem Soc. 2018 Oct 31;140(43):14069-14072. doi: 10.1021/jacs.8b09523. Epub 2018 Oct 18.

3.

Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue.

Lawson CP, Füchtbauer AF, Wranne MS, Giraud T, Floyd T, Dumat B, Andersen NK, H El-Sagheer A, Brown T, Gradén H, Wilhelmsson LM, Grøtli M.

Sci Rep. 2018 Sep 18;8(1):13970. doi: 10.1038/s41598-018-31897-2.

4.

Synthesis and Photophysical Characterization of Azoheteroarenes.

Xu Y, Gao C, Andréasson J, Grøtli M.

Org Lett. 2018 Aug 17;20(16):4875-4879. doi: 10.1021/acs.orglett.8b02014. Epub 2018 Aug 6.

PMID:
30079733
5.

Drug Repositioning for Effective Prostate Cancer Treatment.

Turanli B, Grøtli M, Boren J, Nielsen J, Uhlen M, Arga KY, Mardinoglu A.

Front Physiol. 2018 May 15;9:500. doi: 10.3389/fphys.2018.00500. eCollection 2018. Review.

6.

Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue.

Bood M, Füchtbauer AF, Wranne MS, Ro JJ, Sarangamath S, El-Sagheer AH, Rupert DLM, Fisher RS, Magennis SW, Jones AC, Höök F, Brown T, Kim BH, Dahlén A, Wilhelmsson LM, Grøtli M.

Chem Sci. 2018 Mar 1;9(14):3494-3502. doi: 10.1039/c7sc05448c. eCollection 2018 Apr 14.

7.

Fluorescent nucleobase analogues for base-base FRET in nucleic acids: synthesis, photophysics and applications.

Bood M, Sarangamath S, Wranne MS, Grøtli M, Wilhelmsson LM.

Beilstein J Org Chem. 2018 Jan 10;14:114-129. doi: 10.3762/bjoc.14.7. eCollection 2018. Review.

8.

Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan.

Bilsland E, van Vliet L, Williams K, Feltham J, Carrasco MP, Fotoran WL, Cubillos EFG, Wunderlich G, Grøtli M, Hollfelder F, Jackson V, King RD, Oliver SG.

Sci Rep. 2018 Jan 18;8(1):1038. doi: 10.1038/s41598-018-19549-x.

9.

Network analyses identify liver-specific targets for treating liver diseases.

Lee S, Zhang C, Liu Z, Klevstig M, Mukhopadhyay B, Bergentall M, Cinar R, Ståhlman M, Sikanic N, Park JK, Deshmukh S, Harzandi AM, Kuijpers T, Grøtli M, Elsässer SJ, Piening BD, Snyder M, Smith U, Nielsen J, Bäckhed F, Kunos G, Uhlen M, Boren J, Mardinoglu A.

Mol Syst Biol. 2017 Aug 21;13(8):938. doi: 10.15252/msb.20177703.

10.

Improving the economics of NASH/NAFLD treatment through the use of systems biology.

Bosley J, Boren C, Lee S, Grøtli M, Nielsen J, Uhlen M, Boren J, Mardinoglu A.

Drug Discov Today. 2017 Oct;22(10):1532-1538. doi: 10.1016/j.drudis.2017.07.005. Epub 2017 Jul 20. Review.

PMID:
28736156
11.

Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET.

Wranne MS, Füchtbauer AF, Dumat B, Bood M, El-Sagheer AH, Brown T, Gradén H, Grøtli M, Wilhelmsson LM.

J Am Chem Soc. 2017 Jul 12;139(27):9271-9280. doi: 10.1021/jacs.7b04517. Epub 2017 Jun 27.

12.

Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins.

Danelius E, Pettersson M, Bred M, Min J, Waddell MB, Guy RK, Grøtli M, Erdelyi M.

Org Biomol Chem. 2016 Nov 8;14(44):10386-10393.

PMID:
27731454
13.

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases.

Valencia-Sánchez MI, Rodríguez-Hernández A, Ferreira R, Santamaría-Suárez HA, Arciniega M, Dock-Bregeon AC, Moras D, Beinsteiner B, Mertens H, Svergun D, Brieba LG, Grøtli M, Torres-Larios A.

J Biol Chem. 2016 Jul 8;291(28):14430-46. doi: 10.1074/jbc.M116.730382. Epub 2016 May 23.

14.

Chroman-4-one and chromone based somatostatin β-turn mimetics.

Fridén-Saxin M, Seifert T, Malo M, da Silva Andersson K, Pemberton N, Dyrager C, Friberg A, Dahlén K, Wallén EA, Grøtli M, Luthman K.

Eur J Med Chem. 2016 May 23;114:59-64. doi: 10.1016/j.ejmech.2016.02.046. Epub 2016 Feb 21.

PMID:
26974375
15.

Defects in the calcium-binding region drastically affect the cadherin-like domains of RET tyrosine kinase.

Gao C, Grøtli M, Eriksson LA.

Phys Chem Chem Phys. 2016 Mar 28;18(12):8673-81. doi: 10.1039/c6cp00042h.

PMID:
26950000
16.

An acido- and photochromic molecular device that mimics triode action.

Remón P, Li SM, Grøtli M, Pischel U, Andréasson J.

Chem Commun (Camb). 2016 Mar 28;52(25):4659-62. doi: 10.1039/c6cc00840b.

PMID:
26948249
17.

7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding protein.

Tokugawa M, Masaki Y, Canggadibrata JC, Kaneko K, Shiozawa T, Kanamori T, Grøtli M, Wilhelmsson LM, Sekine M, Seio K.

Chem Commun (Camb). 2016 Mar 7;52(19):3809-12. doi: 10.1039/c5cc09700b.

PMID:
26865112
18.

Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8.

Kumar NV, Yang J, Pillai JK, Rawat S, Solano C, Kumar A, Grøtli M, Stemmler TL, Rosen BP, Tamás MJ.

Mol Cell Biol. 2015 Dec 28;36(6):913-22. doi: 10.1128/MCB.00842-15.

19.

Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction.

Pettersson M, Quant M, Min J, Iconaru L, Kriwacki RW, Waddell MB, Guy RK, Luthman K, Grøtli M.

PLoS One. 2015 Oct 1;10(10):e0137867. doi: 10.1371/journal.pone.0137867. eCollection 2015.

20.

A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos.

Bliman D, Nilsson JR, Kettunen P, Andréasson J, Grøtli M.

Sci Rep. 2015 Aug 24;5:13109. doi: 10.1038/srep13109.

21.

Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design.

Foller Larsen A, Dumat B, Wranne MS, Lawson CP, Preus S, Bood M, Gradén H, Wilhelmsson LM, Grøtli M.

Sci Rep. 2015 Jul 31;5:12653. doi: 10.1038/srep12653.

22.

Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase.

Gao C, Grøtli M, Eriksson LA.

J Mol Model. 2015 Jul;21(7):167. doi: 10.1007/s00894-015-2708-z. Epub 2015 Jun 6.

PMID:
26044359
23.

Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors.

Ferreira R, Nilsson JR, Solano C, Andréasson J, Grøtli M.

Sci Rep. 2015 May 6;5:9769. doi: 10.1038/srep09769.

24.

8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction.

Pettersson M, Bliman D, Jacobsson J, Nilsson JR, Min J, Iconaru L, Guy RK, Kriwacki RW, Andréasson J, Grøtli M.

PLoS One. 2015 May 5;10(5):e0124423. doi: 10.1371/journal.pone.0124423. eCollection 2015.

25.

The unique characteristics of HOG pathway MAPKs in the extremely halotolerant Hortaea werneckii.

Kejžar A, Cibic M, Grøtli M, Plemenitaš A, Lenassi M.

FEMS Microbiol Lett. 2015 Apr;362(8):fnv046. doi: 10.1093/femsle/fnv046. Epub 2015 Mar 30.

PMID:
25825474
26.

Second-generation fluorescent quadracyclic adenine analogues: environment-responsive probes with enhanced brightness.

Dumat B, Bood M, Wranne MS, Lawson CP, Larsen AF, Preus S, Streling J, Gradén H, Wellner E, Grøtli M, Wilhelmsson LM.

Chemistry. 2015 Mar 2;21(10):4039-48. doi: 10.1002/chem.201405759. Epub 2015 Jan 29.

PMID:
25641628
27.

HwHog1 kinase activity is crucial for survival of Hortaea werneckii in extremely hyperosmolar environments.

Kejžar A, Grötli M, Tamás MJ, Plemenitaš A, Lenassi M.

Fungal Genet Biol. 2015 Jan;74:45-58. doi: 10.1016/j.fgb.2014.11.004. Epub 2014 Dec 4.

PMID:
25483129
28.

Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86.

Alao JP, Michlikova S, Dinér P, Grøtli M, Sunnerhagen P.

BMC Cancer. 2014 Nov 20;14:853. doi: 10.1186/1471-2407-14-853.

29.

Towards the development of chromone-based MEK1/2 modulators.

Redwan IN, Dyrager C, Solano C, Fernández de Trocóniz G, Voisin L, Bliman D, Meloche S, Grøtli M.

Eur J Med Chem. 2014 Oct 6;85:127-38. doi: 10.1016/j.ejmech.2014.07.018. Epub 2014 Jul 7.

PMID:
25078316
30.

Synthesis and photophysical characterisation of new fluorescent triazole adenine analogues.

Lawson CP, Dierckx A, Miannay FA, Wellner E, Wilhelmsson LM, Grøtli M.

Org Biomol Chem. 2014 Jul 28;12(28):5158-67. doi: 10.1039/c4ob00904e.

PMID:
24912077
31.

Application of a peptide-based assay to characterize inhibitors targeting protein kinases from yeast.

Veide Vilg J, Dahal S, Ljungdahl T, Grøtli M, Tamás MJ.

Curr Genet. 2014 Aug;60(3):193-200. doi: 10.1007/s00294-014-0424-3. Epub 2014 Mar 19.

PMID:
24643376
32.

Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified proteins.

Reiter W, Anrather D, Dohnal I, Pichler P, Veis J, Grøtli M, Posas F, Ammerer G.

Proteomics. 2012 Oct;12(19-20):3030-43. doi: 10.1002/pmic.201200185. Epub 2012 Sep 19.

33.

Method for activation and recycling of trityl resins.

Redwan IN, Grøtli M.

J Org Chem. 2012 Aug 17;77(16):7071-5. doi: 10.1021/jo300598d. Epub 2012 Aug 6.

PMID:
22809057
34.

Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates.

Sörensson C, Lenman M, Veide-Vilg J, Schopper S, Ljungdahl T, Grøtli M, Tamás MJ, Peck SC, Andreasson E.

Biochem J. 2012 Sep 1;446(2):271-8. doi: 10.1042/BJ20111809.

PMID:
22631074
35.

Preparation of 3-substituted-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amines as RET kinase inhibitors.

Dinér P, Alao JP, Söderlund J, Sunnerhagen P, Grøtli M.

J Med Chem. 2012 May 24;55(10):4872-6. doi: 10.1021/jm3003944. Epub 2012 May 16.

PMID:
22559926
36.

Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase inhibitors.

Dyrager C, Möllers LN, Kjäll LK, Alao JP, Dinér P, Wallner FK, Sunnerhagen P, Grøtli M.

J Med Chem. 2011 Oct 27;54(20):7427-31. doi: 10.1021/jm200818j. Epub 2011 Sep 26.

PMID:
21905739
37.

NMR-based substrate analog docking to Escherichia coli peptidyl-tRNA hydrolase.

Giorgi L, Plateau P, O'Mahony G, Aubard C, Fromant M, Thureau A, Grøtli M, Blanquet S, Bontems F.

J Mol Biol. 2011 Sep 30;412(4):619-33. doi: 10.1016/j.jmb.2011.06.025. Epub 2011 Jun 21.

PMID:
21718701
38.

Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases.

Klein M, Morillas M, Vendrell A, Brive L, Gebbia M, Wallace IM, Giaever G, Nislow C, Posas F, Grøtli M.

PLoS One. 2011;6(6):e20789. doi: 10.1371/journal.pone.0020789. Epub 2011 Jun 17.

39.

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast.

Dinér P, Veide Vilg J, Kjellén J, Migdal I, Andersson T, Gebbia M, Giaever G, Nislow C, Hohmann S, Wysocki R, Tamás MJ, Grøtli M.

PLoS One. 2011;6(5):e20012. doi: 10.1371/journal.pone.0020012. Epub 2011 May 31.

40.

Inhibitors and promoters of tubulin polymerization: synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents.

Dyrager C, Wickström M, Fridén-Saxin M, Friberg A, Dahlén K, Wallén EA, Gullbo J, Grøtli M, Luthman K.

Bioorg Med Chem. 2011 Apr 15;19(8):2659-65. doi: 10.1016/j.bmc.2011.03.005. Epub 2011 Mar 10.

PMID:
21459004
41.

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA.

Dierckx A, Dinér P, El-Sagheer AH, Kumar JD, Brown T, Grøtli M, Wilhelmsson LM.

Nucleic Acids Res. 2011 May;39(10):4513-24. doi: 10.1093/nar/gkr010. Epub 2011 Jan 29.

42.

Positional scanning peptide libraries for kinase substrate specificity determinations: straightforward and reproducible synthesis using pentafluorophenyl esters.

Ljungdahl T, Veide-Vilg J, Wallner F, Tamás MJ, Grøtli M.

J Comb Chem. 2010 Sep 13;12(5):733-42. doi: 10.1021/cc100095y.

PMID:
20608733
43.

KHMDS enhanced SmI(2)-mediated reformatsky type alpha-cyanation.

Ankner T, Fridén-Saxin M, Pemberton N, Seifert T, Grøtli M, Luthman K, Hilmersson G.

Org Lett. 2010 May 21;12(10):2210-3. doi: 10.1021/ol100424y.

PMID:
20429501
44.

Structural influence on radical formation and sensitizing capacity of alkylic limonene hydroperoxide analogues in allergic contact dermatitis.

Johansson SG, Emilsson K, Grøtli M, Börje A.

Chem Res Toxicol. 2010 Mar 15;23(3):677-88. doi: 10.1021/tx900433n.

PMID:
20163165
45.

Synthesis of chiral 1,4-disubstituted-1,2,3-triazole derivatives from amino acids.

Klein M, Krainz K, Redwan IN, Dinér P, Grøtli M.

Molecules. 2009 Dec 9;14(12):5124-43. doi: 10.3390/molecules14125124.

46.

Solid-phase peptide synthesis in water using microwave-assisted heating.

Galanis AS, Albericio F, Grøtli M.

Org Lett. 2009 Oct 15;11(20):4488-91. doi: 10.1021/ol901893p.

PMID:
19757802
47.

Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)-substituted pyrazolo[3,4-d]pyrimidin-4-amines via click chemistry: potential inhibitors of the Plasmodium falciparum PfPK7 protein kinase.

Klein M, Dinér P, Dorin-Semblat D, Doerig C, Grøtli M.

Org Biomol Chem. 2009 Sep 7;7(17):3421-9. doi: 10.1039/b906482f. Epub 2009 Jul 2.

PMID:
19675896
48.

2,6,8-Trisubstituted 3-hydroxychromone derivatives as fluorophores for live-cell imaging.

Dyrager C, Friberg A, Dahlén K, Fridén-Saxin M, Börjesson K, Wilhelmsson LM, Smedh M, Grøtli M, Luthman K.

Chemistry. 2009 Sep 21;15(37):9417-23. doi: 10.1002/chem.200900279.

PMID:
19670192
49.

Synthesis of 2-alkyl-substituted chromone derivatives using microwave irradiation.

Fridén-Saxin M, Pemberton N, Andersson Kda S, Dyrager C, Friberg A, Grøtli M, Luthman K.

J Org Chem. 2009 Apr 3;74(7):2755-9. doi: 10.1021/jo802783z.

PMID:
19323574
50.

Enhanced microwave-assisted method for on-bead disulfide bond formation: synthesis of alpha-conotoxin MII.

Galanis AS, Albericio F, Grøtli M.

Biopolymers. 2009;92(1):23-34. doi: 10.1002/bip.21116.

PMID:
19003899

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