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Items: 1 to 50 of 453

1.

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium.

van den Berg BM, Wang G, Boels MGS, Avramut MC, Jansen E, Sol WMPJ, Lebrin F, Jan van Zonneveld A, de Koning EJP, Vink H, Gröne HJ, Carmeliet P, van der Vlag J, Rabelink TJ.

J Am Soc Nephrol. 2019 Jul 15. pii: ASN.2019020192. doi: 10.1681/ASN.2019020192. [Epub ahead of print]

PMID:
31308073
2.

Association between urinary dickkopf-3, acute kidney injury, and subsequent loss of kidney function in patients undergoing cardiac surgery: an observational cohort study.

Schunk SJ, Zarbock A, Meersch M, Küllmar M, Kellum JA, Schmit D, Wagner M, Triem S, Wagenpfeil S, Gröne HJ, Schäfers HJ, Fliser D, Speer T, Zewinger S.

Lancet. 2019 Aug 10;394(10197):488-496. doi: 10.1016/S0140-6736(19)30769-X. Epub 2019 Jun 12.

PMID:
31202596
3.

O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart From Failure.

Kronlage M, Dewenter M, Grosso J, Fleming T, Oehl U, Lehmann LH, Falcão-Pires I, Leite-Moreira AF, Volk N, Gröne HJ, Müller OJ, Sickmann A, Katus HA, Backs J.

Circulation. 2019 Aug 13;140(7):580-594. doi: 10.1161/CIRCULATIONAHA.117.031942. Epub 2019 Jun 14.

PMID:
31195810
4.

Ganglioside deficiency in hypothalamic POMC neurons promotes body weight gain.

Dieterle V, Herzer S, Gröne HJ, Jennemann R, Nordström V.

Int J Obes (Lond). 2019 Jun 5. doi: 10.1038/s41366-019-0388-y. [Epub ahead of print]

PMID:
31168055
5.

Herniation of the tuft with outgrowth of vessels through the glomerular entrance in diabetic nephropathy damages the juxtaglomerular apparatus.

Löwen J, Gröne E, Gröne HJ, Kriz W.

Am J Physiol Renal Physiol. 2019 Aug 1;317(2):F399-F410. doi: 10.1152/ajprenal.00617.2018. Epub 2019 May 29.

PMID:
31141396
6.

Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibition protects against acute kidney injury.

Morace I, Pilz R, Federico G, Jennemann R, Krunic D, Nordström V, von Gerichten J, Marsching C, Schießl IM, Müthing J, Wunder C, Johannes L, Sandhoff R, Gröne HJ.

Kidney Int. 2019 Aug;96(2):327-341. doi: 10.1016/j.kint.2019.02.010. Epub 2019 Feb 28.

PMID:
31101366
7.

Absolute quantification of donor-derived cell-free DNA as a marker of rejection and graft injury in kidney transplantation: Results from a prospective observational study.

Oellerich M, Shipkova M, Asendorf T, Walson PD, Schauerte V, Mettenmeyer N, Kabakchiev M, Hasche G, Gröne HJ, Friede T, Wieland E, Schwenger V, Schütz E, Beck J.

Am J Transplant. 2019 May 7. doi: 10.1111/ajt.15416. [Epub ahead of print]

PMID:
31062511
8.

Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions.

Kuppe C, Leuchtle K, Wagner A, Kabgani N, Saritas T, Puelles VG, Smeets B, Hakroush S, van der Vlag J, Boor P, Schiffer M, Gröne HJ, Fogo A, Floege J, Moeller MJ.

Kidney Int. 2019 Jul;96(1):80-93. doi: 10.1016/j.kint.2019.01.037. Epub 2019 Feb 27.

PMID:
31029503
9.

Uromodulin-related autosomal-dominant tubulointerstitial kidney disease-pathogenetic insights based on a case.

Reindl J, Gröne HJ, Wolf G, Busch M.

Clin Kidney J. 2018 Nov 12;12(2):172-179. doi: 10.1093/ckj/sfy094. eCollection 2019 Apr.

10.

Rbpj expression in regulatory T cells is critical for restraining TH2 responses.

Delacher M, Schmidl C, Herzig Y, Breloer M, Hartmann W, Brunk F, Kägebein D, Träger U, Hofer AC, Bittner S, Weichenhan D, Imbusch CD, Hotz-Wagenblatt A, Hielscher T, Breiling A, Federico G, Gröne HJ, Schmid RM, Rehli M, Abramson J, Feuerer M.

Nat Commun. 2019 Apr 8;10(1):1621. doi: 10.1038/s41467-019-09276-w.

11.

Erratum.

Bellur SS, Roberts ISD, Troyanov S, Royal V, Coppo R, Cook HT, Cattran D, Arce Terroba Y, Maria Asunis A, Bajema I, Bertoni E, Bruijn JA, Cannata-Ortiz P, Casartelli D, Maria Di Palma A, Ferrario F, Fortunato M, Furci L, Gakiopoulou H, Galesic Ljubanovic D, Giannakakis K, Gomà M, Gröne HJ, Gutiérrez E, Haider SA, Honsova E, Ioachim E, Karkoszka H, Kipgen D, Maldyk J, Mazzucco G, Orhan D, Ozluk Y, Pantzaki A, Perkowska-Ptasinska A, Riispere Z, Soderberg MP, Steenbergen E, Stoppacciaro A, Sundelin Von Feilitzen B, Tardanico R.

Nephrol Dial Transplant. 2019 Mar 16. pii: gfz001. doi: 10.1093/ndt/gfz001. [Epub ahead of print] No abstract available.

PMID:
30879042
12.

Kidney Injury by Variants in the COL4A5 Gene Aggravated by Polymorphisms in Slit Diaphragm Genes Causes Focal Segmental Glomerulosclerosis.

Frese J, Kettwig M, Zappel H, Hofer J, Gröne HJ, Nagel M, Sunder-Plassmann G, Kain R, Neuweiler J, Gross O.

Int J Mol Sci. 2019 Jan 26;20(3). pii: E519. doi: 10.3390/ijms20030519.

13.

Reproducibility of the Oxford classification of immunoglobulin A nephropathy, impact of biopsy scoring on treatment allocation and clinical relevance of disagreements: evidence from the VALidation of IGA study cohort.

Bellur SS, Roberts ISD, Troyanov S, Royal V, Coppo R, Cook HT, Cattran D, Arce Terroba Y, Asunis AM, Bajema I, Bertoni E, Bruijn JA, Cannata-Ortiz P, Casartelli D, Maria Di Palma A, Ferrario F, Fortunato M, Furci L, Gakiopoulou H, Galesic Ljubanovic D, Giannakakis K, Gomà M, Gröne HJ, Gutiérrez EM, Asma Haider S, Honsova E, Ioachim E, Karkoszka H, Kipgen D, Maldyk J, Mazzucco G, Orhan D, Ozluk Y, Pantzaki A, Perkowska-Ptasinska A, Riispere Z, Soderberg MP, Steenbergen E, Stoppacciaro A, Sundelin Von Feilitzen B, Tardanico R.

Nephrol Dial Transplant. 2018 Dec 15. doi: 10.1093/ndt/gfy337. [Epub ahead of print]

PMID:
30561721
14.

The Atypical Chemokine Receptor 2 Limits Progressive Fibrosis after Acute Ischemic Kidney Injury.

Lux M, Blaut A, Eltrich N, Bideak A, Müller MB, Hoppe JM, Gröne HJ, Locati M, Vielhauer V.

Am J Pathol. 2019 Feb;189(2):231-247. doi: 10.1016/j.ajpath.2018.09.016. Epub 2018 Nov 16.

PMID:
30448408
15.

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure.

Müller OJ, Heckmann MB, Ding L, Rapti K, Rangrez AY, Gerken T, Christiansen N, Rennefahrt UEE, Witt H, González Maldonado S, Ternes P, Schwab DM, Ruf T, Hille S, Remes A, Jungmann A, Weis TM, Kreußer JS, Gröne HJ, Backs J, Schatz P, Katus HA, Frey N.

Cardiovasc Res. 2019 Jul 1;115(8):1296-1305. doi: 10.1093/cvr/cvy274.

PMID:
30418544
16.

Experimental ischaemic stroke induces transient cardiac atrophy and dysfunction.

Veltkamp R, Uhlmann S, Marinescu M, Sticht C, Finke D, Gretz N, Gröne HJ, Katus HA, Backs J, Lehmann LH.

J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):54-62. doi: 10.1002/jcsm.12335. Epub 2018 Oct 30.

17.

Unrecognized juvenile nephropathic cystinosis.

Schiefer J, Zenker M, Gröne HJ, Chatzikyrkou C, Mertens PR, Liakopoulos V.

Kidney Int. 2018 Nov;94(5):1027. doi: 10.1016/j.kint.2018.06.001. No abstract available.

PMID:
30348293
18.

Dickkopf-3 (DKK3) in Urine Identifies Patients with Short-Term Risk of eGFR Loss.

Zewinger S, Rauen T, Rudnicki M, Federico G, Wagner M, Triem S, Schunk SJ, Petrakis I, Schmit D, Wagenpfeil S, Heine GH, Mayer G, Floege J, Fliser D, Gröne HJ, Speer T.

J Am Soc Nephrol. 2018 Nov;29(11):2722-2733. doi: 10.1681/ASN.2018040405. Epub 2018 Oct 2.

PMID:
30279273
19.

The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus.

Micakovic T, Papagiannarou S, Clark E, Kuzay Y, Abramovic K, Peters J, Sticht C, Volk N, Fleming T, Nawroth P, Hammes HP, Alenina N, Gröne HJ, Hoffmann SC.

Kidney Int. 2018 Nov;94(5):937-950. doi: 10.1016/j.kint.2018.06.006. Epub 2018 Sep 4.

PMID:
30190172
20.

Queuosine-modified tRNAs confer nutritional control of protein translation.

Tuorto F, Legrand C, Cirzi C, Federico G, Liebers R, Müller M, Ehrenhofer-Murray AE, Dittmar G, Gröne HJ, Lyko F.

EMBO J. 2018 Sep 14;37(18). pii: e99777. doi: 10.15252/embj.201899777. Epub 2018 Aug 9.

21.

Nephron-specific knockin of the PIKfyve-binding-deficient Vac14L156R mutant results in albuminuria and mesangial expansion.

Michgehl U, Skryabin BV, Bayraktar S, Vollenbröker B, Ciarimboli G, Heitplatz B, Van Marck V, Gröne HJ, Pavenstädt H, Weide T.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1307-F1319. doi: 10.1152/ajprenal.00191.2018. Epub 2018 Aug 1.

PMID:
30066585
22.

Biallelic Expression of Mucin-1 in Autosomal Dominant Tubulointerstitial Kidney Disease: Implications for Nongenetic Disease Recognition.

Knaup KX, Hackenbeck T, Popp B, Stoeckert J, Wenzel A, Büttner-Herold M, Pfister F, Schueler M, Seven D, May AM, Halbritter J, Gröne HJ, Reis A, Beck BB, Amann K, Ekici AB, Wiesener MS.

J Am Soc Nephrol. 2018 Sep;29(9):2298-2309. doi: 10.1681/ASN.2018030245. Epub 2018 Jul 26.

PMID:
30049680
23.

Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2-dependent transcription in cardiac myocytes.

Tóth AD, Schell R, Lévay M, Vettel C, Theis P, Haslinger C, Alban F, Werhahn S, Frischbier L, Krebs-Haupenthal J, Thomas D, Gröne HJ, Avkiran M, Katus HA, Wieland T, Backs J.

EMBO Mol Med. 2018 Jul;10(7). pii: e8536. doi: 10.15252/emmm.201708536.

24.

Intracapillary immune complexes recruit and activate slan-expressing CD16+ monocytes in human lupus nephritis.

Olaru F, Döbel T, Lonsdorf AS, Oehrl S, Maas M, Enk AH, Schmitz M, Gröne EF, Gröne HJ, Schäkel K.

JCI Insight. 2018 Jun 7;3(11). pii: 96492. doi: 10.1172/jci.insight.96492. eCollection 2018 Jun 7.

25.

[Progressive renal insufficiency in a 55-year-old man with psoriasis].

Herfurth K, Busch M, Gröne HJ, Wolf G.

Internist (Berl). 2018 Nov;59(11):1204-1207. doi: 10.1007/s00108-018-0446-x. German.

PMID:
29872889
26.

The atypical chemokine receptor 2 limits renal inflammation and fibrosis in murine progressive immune complex glomerulonephritis.

Bideak A, Blaut A, Hoppe JM, Müller MB, Federico G, Eltrich N, Gröne HJ, Locati M, Vielhauer V.

Kidney Int. 2018 Apr;93(4):826-841. doi: 10.1016/j.kint.2017.11.013. Epub 2018 Feb 1.

PMID:
29395335
27.

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart.

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, Schmid RM, Adams RH, Gröne HJ, Hell R, Okun JG, Backs J, Nawroth PP, Herzig S, Fischer A.

Circulation. 2018 Jun 12;137(24):2592-2608. doi: 10.1161/CIRCULATIONAHA.117.029733. Epub 2018 Jan 20.

PMID:
29353241
28.

Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis.

Jennemann R, Federico G, Mathow D, Rabionet M, Rampoldi F, Popovic ZV, Volz M, Hielscher T, Sandhoff R, Gröne HJ.

Oncotarget. 2017 Nov 24;8(65):109201-109216. doi: 10.18632/oncotarget.22648. eCollection 2017 Dec 12.

29.

A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J.

Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11.

PMID:
29227474
30.

The interplay of UV and cutaneous papillomavirus infection in skin cancer development.

Hasche D, Stephan S, Braspenning-Wesch I, Mikulec J, Niebler M, Gröne HJ, Flechtenmacher C, Akgül B, Rösl F, Vinzón SE.

PLoS Pathog. 2017 Nov 30;13(11):e1006723. doi: 10.1371/journal.ppat.1006723. eCollection 2017 Nov.

31.

α-Galactosidase A Genotype N215S Induces a Specific Cardiac Variant of Fabry Disease.

Oder D, Liu D, Hu K, Üçeyler N, Salinger T, Müntze J, Lorenz K, Kandolf R, Gröne HJ, Sommer C, Ertl G, Wanner C, Nordbeck P.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001691. doi: 10.1161/CIRCGENETICS.116.001691.

PMID:
29018006
32.

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4).

Lu S, Liu S, Wietelmann A, Kojonazarov B, Atzberger A, Tang C, Schermuly RT, Gröne HJ, Offermanns S.

PLoS One. 2017 Aug 14;12(8):e0183166. doi: 10.1371/journal.pone.0183166. eCollection 2017.

33.

Glucosylceramide Synthase Is Involved in Development of Invariant Natural Killer T Cells.

Popovic ZV, Rabionet M, Jennemann R, Krunic D, Sandhoff R, Gröne HJ, Porubsky S.

Front Immunol. 2017 Jul 21;8:848. doi: 10.3389/fimmu.2017.00848. eCollection 2017.

34.

The hormetic functions of Wnt pathways in tubular injury.

Gröne EF, Federico G, Nelson PJ, Arnold B, Gröne HJ.

Pflugers Arch. 2017 Aug;469(7-8):899-906. doi: 10.1007/s00424-017-2018-7. Epub 2017 Jul 6. Review.

35.

Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis.

Bickelhaupt S, Erbel C, Timke C, Wirkner U, Dadrich M, Flechsig P, Tietz A, Pföhler J, Gross W, Peschke P, Hoeltgen L, Katus HA, Gröne HJ, Nicolay NH, Saffrich R, Debus J, Sternlicht MD, Seeley TW, Lipson KE, Huber PE.

J Natl Cancer Inst. 2017 Aug 1;109(8). doi: 10.1093/jnci/djw339.

PMID:
28376190
36.

Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals.

von Gerichten J, Schlosser K, Lamprecht D, Morace I, Eckhardt M, Wachten D, Jennemann R, Gröne HJ, Mack M, Sandhoff R.

J Lipid Res. 2017 Jun;58(6):1247-1258. doi: 10.1194/jlr.D076190. Epub 2017 Apr 3.

37.

Hyperosmolarity impedes the cross-priming competence of dendritic cells in a TRIF-dependent manner.

Popovic ZV, Embgenbroich M, Chessa F, Nordström V, Bonrouhi M, Hielscher T, Gretz N, Wang S, Mathow D, Quast T, Schloetel JG, Kolanus W, Burgdorf S, Gröne HJ.

Sci Rep. 2017 Mar 22;7(1):311. doi: 10.1038/s41598-017-00434-y.

38.

ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy.

Sulaj A, Kopf S, Gröne E, Gröne HJ, Hoffmann S, Schleicher E, Häring HU, Schwenger V, Herzig S, Fleming T, Nawroth PP, von Bauer R.

J Diabetes Complications. 2017 Jun;31(6):1058-1065. doi: 10.1016/j.jdiacomp.2017.01.002. Epub 2017 Jan 21.

PMID:
28325697
39.

Accumulation of worn-out GBM material substantially contributes to mesangial matrix expansion in diabetic nephropathy.

Kriz W, Löwen J, Federico G, van den Born J, Gröne E, Gröne HJ.

Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F1101-F1111. doi: 10.1152/ajprenal.00020.2017. Epub 2017 Feb 22.

40.

Analysis of FOXP3+ regulatory T cell subpopulations in peripheral blood and tissue of patients with systemic lupus erythematosus.

Schmidt A, Rieger CC, Venigalla RK, Éliás S, Max R, Lorenz HM, Gröne HJ, Krammer PH, Kuhn A.

Immunol Res. 2017 Apr;65(2):551-563. doi: 10.1007/s12026-017-8904-4.

PMID:
28224362
41.

Ezetimibe reduces cholesterol content and NF-kappaB activation in liver but not in intestinal tissue in guinea pigs.

Fraunberger P, Gröne E, Gröne HJ, Drexel H, Walli AK.

J Inflamm (Lond). 2017 Feb 2;14:3. doi: 10.1186/s12950-017-0150-y. eCollection 2017.

42.

Circulating fibronectin contributes to mesangial expansion in a murine model of type 1 diabetes.

Klemis V, Ghura H, Federico G, Würfel C, Bentmann A, Gretz N, Miyazaki T, Gröne HJ, Nakchbandi IA.

Kidney Int. 2017 Jun;91(6):1374-1385. doi: 10.1016/j.kint.2016.12.006. Epub 2017 Jan 31.

PMID:
28159318
43.

Deficiency of N-myristoylation reveals calcineurin activity as regulator of IFN-γ-producing γδ T cells.

Rampoldi F, Brunk F, Bonrouhi M, Federico G, Krunic D, Porubsky S, Gröne HJ, Popovic ZV.

J Leukoc Biol. 2017 Apr;101(4):1005-1014. doi: 10.1189/jlb.1A0616-264R. Epub 2017 Jan 6.

PMID:
28062573
44.

Investigations of Glucocorticoid Action in GN.

Kuppe C, van Roeyen C, Leuchtle K, Kabgani N, Vogt M, Van Zandvoort M, Smeets B, Floege J, Gröne HJ, Moeller MJ.

J Am Soc Nephrol. 2017 May;28(5):1408-1420. doi: 10.1681/ASN.2016010060. Epub 2016 Nov 28.

45.

Correction: E6 and E7 from Beta Hpv38 Cooperate with Ultraviolet Light in the Development of Actinic Keratosis-Like Lesions and Squamous Cell Carcinoma in Mice.

Viarisio D, Mueller-Decker K, Kloz U, Aengeneyndt B, Kopp-Schneider A, Gröne HJ, Gheit T, Flechtenmacher C, Gissmann L, Tommasino M.

PLoS Pathog. 2016 Oct 28;12(10):e1006005. doi: 10.1371/journal.ppat.1006005. eCollection 2016 Oct.

46.

Rat kidney lipid composition addressed by mass spectrometry imaging.

Sandhoff R, Gröne HJ.

Kidney Int. 2016 Nov;90(5):1129-1130. doi: 10.1016/j.kint.2016.07.033. No abstract available.

PMID:
27742183
47.

Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis.

Federico G, Meister M, Mathow D, Heine GH, Moldenhauer G, Popovic ZV, Nordström V, Kopp-Schneider A, Hielscher T, Nelson PJ, Schaefer F, Porubsky S, Fliser D, Arnold B, Gröne HJ.

JCI Insight. 2016 Jan 21;1(1):e84916. doi: 10.1172/jci.insight.84916.

48.

Inducible cardiomyocyte-specific deletion of CaM kinase II protects from pressure overload-induced heart failure.

Kreusser MM, Lehmann LH, Wolf N, Keranov S, Jungmann A, Gröne HJ, Müller OJ, Katus HA, Backs J.

Basic Res Cardiol. 2016 Nov;111(6):65. Epub 2016 Sep 28.

PMID:
27683174
49.

Lipid microdomain modification sustains neuronal viability in models of Alzheimer's disease.

Herzer S, Meldner S, Rehder K, Gröne HJ, Nordström V.

Acta Neuropathol Commun. 2016 Sep 17;4(1):103. doi: 10.1186/s40478-016-0354-z.

50.

Preclinical evaluation of a diabody-based (177)Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy in a non-Hodgkin lymphoma mouse model.

Weber T, Bötticher B, Arndt MA, Mier W, Sauter M, Exner E, Keller A, Krämer S, Leotta K, Wischnjow A, Grosse-Hovest L, Strumberg D, Jäger D, Gröne HJ, Haberkorn U, Brem G, Krauss J.

Cancer Lett. 2016 Oct 28;381(2):296-304. doi: 10.1016/j.canlet.2016.08.007. Epub 2016 Aug 11.

PMID:
27524505

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