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Items: 1 to 50 of 69

1.

Role of innate immunity and altered intestinal motility in LPS- and MnCl2-induced intestinal intussusception in mice.

Killoran KE, Miller AD, Uray KS, Weisbrodt NW, Pautler RG, Goyert SM, van Rooijen N, Conner ME.

Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1;306(5):G445-53. doi: 10.1152/ajpgi.00264.2013. Epub 2014 Jan 9.

2.

Innate immune responses to TLR2 and TLR4 agonists differ between baboons, chimpanzees and humans.

Brinkworth JF, Pechenkina EA, Silver J, Goyert SM.

J Med Primatol. 2012 Dec;41(6):388-93. doi: 10.1111/jmp.12002. Epub 2012 Sep 17.

3.

Differential expression of CD14-dependent and independent pathways for chemokine induction regulates neutrophil trafficking in infection.

Metkar S, Kim KS, Silver J, Goyert SM.

J Leukoc Biol. 2012 Aug;92(2):389-96. doi: 10.1189/jlb.0112011. Epub 2012 May 16.

4.

Editorial: PD-1, a new target for sepsis treatment: better late than never.

Goyert SM, Silver J.

J Leukoc Biol. 2010 Aug;88(2):225-6. doi: 10.1189/jlb.0410240. No abstract available.

PMID:
20679071
5.

Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice.

de Buhr MF, Hedrich HJ, Westendorf AM, Obermeier F, Hofmann C, Zschemisch NH, Buer J, Bumann D, Goyert SM, Bleich A.

Inflamm Bowel Dis. 2009 Dec;15(12):1824-36. doi: 10.1002/ibd.21030. Epub 2009 Jul 27.

PMID:
19637338
6.

Pivotal role of the alpha(2A)-adrenoceptor in producing inflammation and organ injury in a rat model of sepsis.

Miksa M, Das P, Zhou M, Wu R, Dong W, Ji Y, Goyert SM, Ravikumar TS, Wang P.

PLoS One. 2009;4(5):e5504. doi: 10.1371/journal.pone.0005504. Epub 2009 May 11.

7.
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Injection of lipopolysaccharide induces the migration of splenic neutrophils to the T cell area of the white pulp: role of CD14 and CXC chemokines.

Kesteman N, Vansanten G, Pajak B, Goyert SM, Moser M.

J Leukoc Biol. 2008 Mar;83(3):640-7. Epub 2007 Dec 21.

PMID:
18156186
9.

Expression of Legionella pneumophila paralogous lipid A biosynthesis genes under different growth conditions.

Albers U, Tiaden A, Spirig T, Al Alam D, Goyert SM, Gangloff SC, Hilbi H.

Microbiology. 2007 Nov;153(Pt 11):3817-29.

PMID:
17975091
10.

Role of CD14 in responses to clinical isolates of Escherichia coli: effects of K1 capsule expression.

Metkar S, Awasthi S, Denamur E, Kim KS, Gangloff SC, Teichberg S, Haziot A, Silver J, Goyert SM.

Infect Immun. 2007 Nov;75(11):5415-24. Epub 2007 Aug 20.

11.

In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice.

Prince JM, Levy RM, Bartels J, Baratt A, Kane JM 3rd, Lagoa C, Rubin J, Day J, Wei J, Fink MP, Goyert SM, Clermont G, Billiar TR, Vodovotz Y.

Mol Med. 2006 Apr-Jun;12(4-6):88-96.

12.

Influence of CD14 on ligand interactions between lipopolysaccharide and its receptor complex.

Gangloff SC, Zähringer U, Blondin C, Guenounou M, Silver J, Goyert SM.

J Immunol. 2005 Sep 15;175(6):3940-5.

13.

Signaling through CD14 attenuates the inflammatory response to Borrelia burgdorferi, the agent of Lyme disease.

Benhnia MR, Wroblewski D, Akhtar MN, Patel RA, Lavezzi W, Gangloff SC, Goyert SM, Caimano MJ, Radolf JD, Sellati TJ.

J Immunol. 2005 Feb 1;174(3):1539-48.

14.

Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.

Devitt A, Parker KG, Ogden CA, Oldreive C, Clay MF, Melville LA, Bellamy CO, Lacy-Hulbert A, Gangloff SC, Goyert SM, Gregory CD.

J Cell Biol. 2004 Dec 20;167(6):1161-70.

15.

Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms.

Chen G, Li J, Ochani M, Rendon-Mitchell B, Qiang X, Susarla S, Ulloa L, Yang H, Fan S, Goyert SM, Wang P, Tracey KJ, Sama AE, Wang H.

J Leukoc Biol. 2004 Nov;76(5):994-1001. Epub 2004 Aug 26.

PMID:
15331624
16.

CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan-polysaccharide complexes of Gram-positive bacterial cell walls.

Li X, Bradford BU, Dalldorf F, Goyert SM, Stimpson SA, Thurman RG, Makarov SS.

Arthritis Res Ther. 2004;6(3):R273-81. Epub 2004 Apr 27.

17.

CD14-deficient mice are protected against lipopolysaccharide-induced cardiac inflammation and left ventricular dysfunction.

Knuefermann P, Nemoto S, Misra A, Nozaki N, Defreitas G, Goyert SM, Carabello BA, Mann DL, Vallejo JG.

Circulation. 2002 Nov 12;106(20):2608-15.

PMID:
12427659
18.

Activation of human and mouse Kupffer cells by lipopolysaccharide is mediated by CD14.

Su GL, Goyert SM, Fan MH, Aminlari A, Gong KQ, Klein RD, Myc A, Alarcon WH, Steinstraesser L, Remick DG, Wang SC.

Am J Physiol Gastrointest Liver Physiol. 2002 Sep;283(3):G640-5.

19.
20.

The role of Kupffer cell oxidant production in early ethanol-induced liver disease.

Wheeler MD, Kono H, Yin M, Nakagami M, Uesugi T, Arteel GE, Gäbele E, Rusyn I, Yamashina S, Froh M, Adachi Y, Iimuro Y, Bradford BU, Smutney OM, Connor HD, Mason RP, Goyert SM, Peters JM, Gonzalez FJ, Samulski RJ, Thurman RG.

Free Radic Biol Med. 2001 Dec 15;31(12):1544-9. Review.

PMID:
11744328
21.

Parameters influencing membrane CD14 expression and soluble CD14 levels in sepsis.

Glück T, Silver J, Epstein M, Cao P, Farber B, Goyert SM.

Eur J Med Res. 2001 Aug 27;6(8):351-8.

PMID:
11549517
22.

Induction of TNF-alpha and MnSOD by endotoxin: role of membrane CD14 and Toll-like receptor-4.

Tsan MF, Clark RN, Goyert SM, White JE.

Am J Physiol Cell Physiol. 2001 Jun;280(6):C1422-30.

23.

Reduced early alcohol-induced liver injury in CD14-deficient mice.

Yin M, Bradford BU, Wheeler MD, Uesugi T, Froh M, Goyert SM, Thurman RG.

J Immunol. 2001 Apr 1;166(7):4737-42.

24.
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26.

CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression.

Perera PY, Mayadas TN, Takeuchi O, Akira S, Zaks-Zilberman M, Goyert SM, Vogel SN.

J Immunol. 2001 Jan 1;166(1):574-81.

27.

Reduced bacterial dissemination and liver injury in CD14-deficient mice following a chronic abscess-forming peritonitis induced by Bacteroides fragilis.

Woltmann A, Gangloff SC, Bruch HP, Rietschel ET, Solbach W, Silver J, Goyert SM.

Med Microbiol Immunol. 1999 Mar;187(3):149-56.

PMID:
10206146
28.

CD14 plays no major role in shock induced by Staphylococcus aureus but down-regulates TNF-alpha production.

Haziot A, Hijiya N, Schultz K, Zhang F, Gangloff SC, Goyert SM.

J Immunol. 1999 Apr 15;162(8):4801-5.

29.

Lipopolysaccharide structure influences the macrophage response via CD14-independent and CD14-dependent pathways.

Gangloff SC, Hijiya N, Haziot A, Goyert SM.

Clin Infect Dis. 1999 Mar;28(3):491-6.

PMID:
10194066
30.

Expression of CD14 by hepatocytes: upregulation by cytokines during endotoxemia.

Liu S, Khemlani LS, Shapiro RA, Johnson ML, Liu K, Geller DA, Watkins SC, Goyert SM, Billiar TR.

Infect Immun. 1998 Nov;66(11):5089-98.

31.

Acute pancreatitis induces cytokine production in endotoxin-resistant mice.

Eubanks JW 3rd, Sabek O, Kotb M, Gaber LW, Henry J, Hijiya N, Britt LG, Gaber AO, Goyert SM.

Ann Surg. 1998 Jun;227(6):904-11.

32.

Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide.

Sellati TJ, Bouis DA, Kitchens RL, Darveau RP, Pugin J, Ulevitch RJ, Gangloff SC, Goyert SM, Norgard MV, Radolf JD.

J Immunol. 1998 Jun 1;160(11):5455-64.

33.

Role of CD14 in infection: studies in CD14-deficient mice.

Haziot A, Hijiya N, Goyert SM.

Prog Clin Biol Res. 1998;397:255-60. No abstract available.

PMID:
9575566
34.

CD14 dependent and independent signaling pathways in murine macrophages from normal and CD14 "knockout" (CD14KO) mice stimulated with LPS or taxol.

Vogel SN, Perera PY, Detore GR, Bhat N, Carboni JM, Haziot A, Goyert SM.

Prog Clin Biol Res. 1998;397:137-46. Review. No abstract available.

PMID:
9575554
35.
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38.

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice.

Haziot A, Ferrero E, Köntgen F, Hijiya N, Yamamoto S, Silver J, Stewart CL, Goyert SM.

Immunity. 1996 Apr;4(4):407-14.

39.

CD14-independent responses to LPS require a serum factor that is absent from neonates.

Cohen L, Haziot A, Shen DR, Lin XY, Sia C, Harper R, Silver J, Goyert SM.

J Immunol. 1995 Dec 1;155(11):5337-42.

PMID:
7594548
40.

Recombinant soluble CD14 prevents mortality in mice treated with endotoxin (lipopolysaccharide).

Haziot A, Rong GW, Lin XY, Silver J, Goyert SM.

J Immunol. 1995 Jun 15;154(12):6529-32.

PMID:
7539025
41.

Recombinant soluble CD14 inhibits LPS-induced mortality in a murine model.

Goyert SM, Haziot A.

Prog Clin Biol Res. 1995;392:479-83. No abstract available.

PMID:
8524955
42.

CD14-deficient mice are exquisitely insensitive to the effects of LPS.

Haziot A, Ferrero E, Lin XY, Stewart CL, Goyert SM.

Prog Clin Biol Res. 1995;392:349-51. No abstract available.

PMID:
8524940
43.

Inhibition of lipopolysaccharide and IL-1 but not of TNF-induced activation of human endothelial cells by suramin.

Strassmann G, Graber N, Goyert SM, Fong M, McCullers S, Rong GW, Beall LD.

J Immunol. 1994 Sep 1;153(5):2239-47.

PMID:
7519646
44.

Recombinant soluble CD14 inhibits LPS-induced tumor necrosis factor-alpha production by cells in whole blood.

Haziot A, Rong GW, Bazil V, Silver J, Goyert SM.

J Immunol. 1994 Jun 15;152(12):5868-76.

PMID:
7515917
45.

Recombinant soluble CD14 mediates the activation of endothelial cells by lipopolysaccharide.

Haziot A, Rong GW, Silver J, Goyert SM.

J Immunol. 1993 Aug 1;151(3):1500-7.

PMID:
7687634
46.

Endotoxin-mediated endothelial cell injury and activation: role of soluble CD14.

Arditi M, Zhou J, Dorio R, Rong GW, Goyert SM, Kim KS.

Infect Immun. 1993 Aug;61(8):3149-56.

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49.

Transgenic mice expressing human CD14 are hypersensitive to lipopolysaccharide.

Ferrero E, Jiao D, Tsuberi BZ, Tesio L, Rong GW, Haziot A, Goyert SM.

Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2380-4.

50.

Mouse placental macrophages have a decreased ability to present antigen.

Chang MD, Pollard JW, Khalili H, Goyert SM, Diamond B.

Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):462-6.

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