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Items: 23


Identification of a T follicular helper cell subset that drives anaphylactic IgE.

Gowthaman U, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC.

Science. 2019 Aug 30;365(6456). pii: eaaw6433. doi: 10.1126/science.aaw6433. Epub 2019 Aug 1.


Adding intestinal insult to skin injury.

Gowthaman U, Eisenbarth SC.

Sci Immunol. 2019 Jul 5;4(37). pii: eaat0809. doi: 10.1126/sciimmunol.aat0809.


IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection.

Liu D, Yin X, Olyha SJ, Nascimento MSL, Chen P, White T, Gowthaman U, Zhang T, Gertie JA, Zhang B, Xu L, Yurieva M, Devine L, Williams A, Eisenbarth SC.

Immunity. 2019 Jul 16;51(1):64-76.e7. doi: 10.1016/j.immuni.2019.05.011. Epub 2019 Jun 20.


Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses.

Krishnaswamy JK, Gowthaman U, Zhang B, Mattsson J, Szeponik L, Liu D, Wu R, White T, Calabro S, Xu L, Collet MA, Yurieva M, Alsén S, Fogelstrand P, Walter A, Heath WR, Mueller SN, Yrlid U, Williams A, Eisenbarth SC.

Sci Immunol. 2017 Dec 1;2(18). pii: eaam9169. doi: 10.1126/sciimmunol.aam9169.


Differential Intrasplenic Migration of Dendritic Cell Subsets Tailors Adaptive Immunity.

Calabro S, Liu D, Gallman A, Nascimento MS, Yu Z, Zhang TT, Chen P, Zhang B, Xu L, Gowthaman U, Krishnaswamy JK, Haberman AM, Williams A, Eisenbarth SC.

Cell Rep. 2016 Aug 30;16(9):2472-85. doi: 10.1016/j.celrep.2016.07.076. Epub 2016 Aug 18.


Bridging channel dendritic cells induce immunity to transfused red blood cells.

Calabro S, Gallman A, Gowthaman U, Liu D, Chen P, Liu J, Krishnaswamy JK, Nascimento MS, Xu L, Patel SR, Williams A, Tormey CA, Hod EA, Spitalnik SL, Zimring JC, Hendrickson JE, Stowell SR, Eisenbarth SC.

J Exp Med. 2016 May 30;213(6):887-96. doi: 10.1084/jem.20151720. Epub 2016 May 16.


A novel therapeutic strategy of lipidated promiscuous peptide against Mycobacterium tuberculosis by eliciting Th1 and Th17 immunity of host.

Rai PK, Chodisetti SB, Nadeem S, Maurya SK, Gowthaman U, Zeng W, Janmeja AK, Jackson DC, Agrewala JN.

Sci Rep. 2016 Apr 7;6:23917. doi: 10.1038/srep23917.


Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.

Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3056-61. doi: 10.1073/pnas.1501554112. Epub 2015 Feb 23.


Triggering through Toll-like receptor 2 limits chronically stimulated T-helper type 1 cells from undergoing exhaustion.

Chodisetti SB, Gowthaman U, Rai PK, Vidyarthi A, Khan N, Agrewala JN.

J Infect Dis. 2015 Feb 1;211(3):486-96. doi: 10.1093/infdis/jiu472. Epub 2014 Aug 25.


Challenges and solutions for a rational vaccine design for TB-endemic regions.

Gowthaman U, Mushtaq K, Tan AC, Rai PK, Jackson DC, Agrewala JN.

Crit Rev Microbiol. 2015;41(3):389-98. doi: 10.3109/1040841X.2013.859125. Epub 2014 Feb 4. Review.


Lipidated promiscuous peptide augments the expression of MHC-II molecules on dendritic cells and activates T cells.

Gowthaman U, Rai PK, Zeng W, Jackson DC, Agrewala JN.

Indian J Med Res. 2013 Nov;138(5):744-8.


Molecular mimicry: good artists copy, great artists steal.

Gowthaman U, Eswarakumar VP.

Virulence. 2013 Aug 15;4(6):433-4. doi: 10.4161/viru.25780. Epub 2013 Jul 17. No abstract available.


Lipidated promiscuous peptides vaccine for tuberculosis-endemic regions.

Gowthaman U, Rai PK, Khan N, Jackson DC, Agrewala JN.

Trends Mol Med. 2012 Oct;18(10):607-14. doi: 10.1016/j.molmed.2012.07.008. Epub 2012 Aug 30. Review.


Manipulation of costimulatory molecules by intracellular pathogens: veni, vidi, vici!!

Khan N, Gowthaman U, Pahari S, Agrewala JN.

PLoS Pathog. 2012;8(6):e1002676. doi: 10.1371/journal.ppat.1002676. Epub 2012 Jun 14. Review.


Potential T cell epitopes of Mycobacterium tuberculosis that can instigate molecular mimicry against host: implications in autoimmune pathogenesis.

Chodisetti SB, Rai PK, Gowthaman U, Pahari S, Agrewala JN.

BMC Immunol. 2012 Mar 21;13:13. doi: 10.1186/1471-2172-13-13.


Promiscuous peptide of 16 kDa antigen linked to Pam2Cys protects against Mycobacterium tuberculosis by evoking enduring memory T-cell response.

Gowthaman U, Singh V, Zeng W, Jain S, Siddiqui KF, Chodisetti SB, Gurram RK, Parihar P, Gupta P, Gupta UD, Jackson DC, Agrewala JN.

J Infect Dis. 2011 Nov;204(9):1328-38. doi: 10.1093/infdis/jir548. Epub 2011 Sep 20.


Co-administration of IL-1+IL-6+TNF-α with Mycobacterium tuberculosis infected macrophages vaccine induces better protective T cell memory than BCG.

Singh V, Jain S, Gowthaman U, Parihar P, Gupta P, Gupta UD, Agrewala JN.

PLoS One. 2011 Jan 19;6(1):e16097. doi: 10.1371/journal.pone.0016097. Erratum in: PLoS One. 2014;9(3):e92631.


T cell help to B cells in germinal centers: putting the jigsaw together.

Gowthaman U, Chodisetti SB, Agrewala JN.

Int Rev Immunol. 2010 Aug;29(4):403-20. doi: 10.3109/08830185.2010.496503. Review.


Coadministration of interleukins 7 and 15 with bacille Calmette-Guérin mounts enduring T cell memory response against Mycobacterium tuberculosis.

Singh V, Gowthaman U, Jain S, Parihar P, Banskar S, Gupta P, Gupta UD, Agrewala JN.

J Infect Dis. 2010 Aug 15;202(3):480-9. doi: 10.1086/653827.


Evaluation of different generic in silico methods for predicting HLA class I binding peptide vaccine candidates using a reverse approach.

Gowthaman U, Chodisetti SB, Parihar P, Agrewala JN.

Amino Acids. 2010 Nov;39(5):1333-42. doi: 10.1007/s00726-010-0579-2. Epub 2010 Apr 9.


In silico methods for predicting T-cell epitopes: Dr Jekyll or Mr Hyde?

Gowthaman U, Agrewala JN.

Expert Rev Proteomics. 2009 Oct;6(5):527-37. doi: 10.1586/epr.09.71. Review.


Molecular docking studies of dithionitrobenzoic acid and its related compounds to protein disulfide isomerase: computational screening of inhibitors to HIV-1 entry.

Gowthaman U, Jayakanthan M, Sundar D.

BMC Bioinformatics. 2008 Dec 12;9 Suppl 12:S14. doi: 10.1186/1471-2105-9-S12-S14.


In silico tools for predicting peptides binding to HLA-class II molecules: more confusion than conclusion.

Gowthaman U, Agrewala JN.

J Proteome Res. 2008 Jan;7(1):154-63. Epub 2007 Nov 23.


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