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Items: 1 to 50 of 340

1.

The role of gut microbiota in obesity, diabetes mellitus, and effect of metformin: new insights into old diseases.

Pascale A, Marchesi N, Govoni S, Coppola A, Gazzaruso C.

Curr Opin Pharmacol. 2019 Apr 20;49:1-5. doi: 10.1016/j.coph.2019.03.011. [Epub ahead of print] Review.

PMID:
31015106
2.

Experimental Paradigm for the Assessment of the Non-pharmacological Mechanism of Action in Medical Device Classification: The Example of Glycerine as Laxative.

Sardi C, Garetto S, Capone L, Galbiati V, Racchi M, Govoni S, Giovagnoni E, Lucci J.

Front Pharmacol. 2018 Dec 7;9:1410. doi: 10.3389/fphar.2018.01410. eCollection 2018.

3.

The Role of Endogenous Neuroprotective Mechanisms in the Prevention of Retinal Ganglion Cells Degeneration.

Pietrucha-Dutczak M, Amadio M, Govoni S, Lewin-Kowalik J, Smedowski A.

Front Neurosci. 2018 Nov 15;12:834. doi: 10.3389/fnins.2018.00834. eCollection 2018. Review.

4.

Beta-amyloid short- and long-term synaptic entanglement.

Lanni C, Fagiani F, Racchi M, Preda S, Pascale A, Grilli M, Allegri N, Govoni S.

Pharmacol Res. 2019 Jan;139:243-260. doi: 10.1016/j.phrs.2018.11.018. Epub 2018 Nov 22. Review.

PMID:
30471405
5.

Systematic Review and Meta-Analysis on Neuropsychological Effects of Long-Term Use of Opioids in Patients With Chronic Noncancer Pain.

Allegri N, Mennuni S, Rulli E, Vanacore N, Corli O, Floriani I, De Simone I, Allegri M, Govoni S, Vecchi T, Sandrini G, Liccione D, Biagioli E.

Pain Pract. 2019 Mar;19(3):328-343. doi: 10.1111/papr.12741. Epub 2018 Dec 10.

PMID:
30354006
6.

Microbiota and metabolic diseases.

Pascale A, Marchesi N, Marelli C, Coppola A, Luzi L, Govoni S, Giustina A, Gazzaruso C.

Endocrine. 2018 Sep;61(3):357-371. doi: 10.1007/s12020-018-1605-5. Epub 2018 May 2. Review.

PMID:
29721802
7.

Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways.

Marchesi N, Thongon N, Pascale A, Provenzani A, Koskela A, Korhonen E, Smedowski A, Govoni S, Kauppinen A, Kaarniranta K, Amadio M.

Oxid Med Cell Longev. 2018 Feb 8;2018:4956080. doi: 10.1155/2018/4956080. eCollection 2018.

8.

Drug prescription appropriateness in the elderly: an Italian study.

Allegri N, Rossi F, Del Signore F, Bertazzoni P, Bellazzi R, Sandrini G, Vecchi T, Liccione D, Pascale A, Govoni S.

Clin Interv Aging. 2017 Feb 10;12:325-333. doi: 10.2147/CIA.S109125. eCollection 2017. Erratum in: Clin Interv Aging. 2017 Dec 15;12 :2131.

9.

Heat shock protein 70-hom gene polymorphism and protein expression in multiple sclerosis.

Boiocchi C, Monti MC, Osera C, Mallucci G, Pistono C, Ferraro OE, Nosari G, Romani A, Cuccia M, Govoni S, Pascale A, Montomoli C, Bergamaschi R.

J Neuroimmunol. 2016 Sep 15;298:189-93. doi: 10.1016/j.jneuroim.2016.07.011. Epub 2016 Jul 15.

PMID:
27609295
10.

Insights into the definition of terms in European medical device regulation.

Racchi M, Govoni S, Lucchelli A, Capone L, Giovagnoni E.

Expert Rev Med Devices. 2016 Oct;13(10):907-917. Epub 2016 Aug 25. Review.

PMID:
27559622
11.

Nanosystems based on siRNA silencing HuR expression counteract diabetic retinopathy in rat.

Amadio M, Pascale A, Cupri S, Pignatello R, Osera C, D Agata V, D Amico AG, Leggio GM, Ruozi B, Govoni S, Drago F, Bucolo C.

Pharmacol Res. 2016 Sep;111:713-720. doi: 10.1016/j.phrs.2016.07.042. Epub 2016 Jul 27.

PMID:
27475885
12.

PKC Activation Counteracts ADAM10 Deficit in HuD-Silenced Neuroblastoma Cells.

Marchesi N, Amadio M, Colombrita C, Govoni S, Ratti A, Pascale A.

J Alzheimers Dis. 2016 Sep 6;54(2):535-47. doi: 10.3233/JAD-160299.

PMID:
27472877
13.

Human Genetic Variability Contributes to Postoperative Morphine Consumption.

De Gregori M, Diatchenko L, Ingelmo PM, Napolioni V, Klepstad P, Belfer I, Molinaro V, Garbin G, Ranzani GN, Alberio G, Normanno M, Lovisari F, Somaini M, Govoni S, Mura E, Bugada D, Niebel T, Zorzetto M, De Gregori S, Molinaro M, Fanelli G, Allegri M.

J Pain. 2016 May;17(5):628-36. doi: 10.1016/j.jpain.2016.02.003. Epub 2016 Feb 21.

PMID:
26902643
14.

Abstinence from cocaine-self-administration activates the nELAV/GAP -43 pathway in the hippocampus: A stress-related effect?

Pascale A, Osera C, Moro F, Di Clemente A, Giannotti G, Caffino L, Govoni S, Fumagalli F, Cervo L.

Hippocampus. 2016 Jun;26(6):700-4. doi: 10.1002/hipo.22572. Epub 2016 Feb 25.

PMID:
26850084
15.

Targeting VEGF in eye neovascularization: What's new?: A comprehensive review on current therapies and oligonucleotide-based interventions under development.

Amadio M, Govoni S, Pascale A.

Pharmacol Res. 2016 Jan;103:253-69. doi: 10.1016/j.phrs.2015.11.027. Epub 2015 Dec 8. Review.

16.

Induction of VEGFA mRNA translation by CoCl2 mediated by HuR.

Osera C, Martindale JL, Amadio M, Kim J, Yang X, Moad CA, Indig FE, Govoni S, Abdelmohsen K, Gorospe M, Pascale A.

RNA Biol. 2015;12(10):1121-30. doi: 10.1080/15476286.2015.1085276. Epub 2015 Sep 1.

17.

Defective DNA repair and increased chromatin binding of DNA repair factors in Down syndrome fibroblasts.

Necchi D, Pinto A, Tillhon M, Dutto I, Serafini MM, Lanni C, Govoni S, Racchi M, Prosperi E.

Mutat Res. 2015 Oct;780:15-23. doi: 10.1016/j.mrfmmm.2015.07.009. Epub 2015 Jul 26.

PMID:
26258283
18.

Pre-exposure of neuroblastoma cell line to pulsed electromagnetic field prevents H2 O2 -induced ROS production by increasing MnSOD activity.

Osera C, Amadio M, Falone S, Fassina L, Magenes G, Amicarelli F, Ricevuti G, Govoni S, Pascale A.

Bioelectromagnetics. 2015 Apr;36(3):219-32. doi: 10.1002/bem.21900. Epub 2015 Feb 23.

PMID:
25708841
19.

Involvement of ELAV RNA-binding proteins in the post-transcriptional regulation of HO-1.

Amadio M, Scapagnini G, Davinelli S, Calabrese V, Govoni S, Pascale A.

Front Cell Neurosci. 2015 Jan 15;8:459. doi: 10.3389/fncel.2014.00459. eCollection 2014.

20.

Serotonin transporter polymorphism modifies the association between depressive symptoms and sleep onset latency complaint in elderly people: results from the 'InveCe.Ab' study.

Polito L, Davin A, Vaccaro R, Abbondanza S, Govoni S, Racchi M, Guaita A.

J Sleep Res. 2015 Apr;24(2):215-22. doi: 10.1111/jsr.12248. Epub 2014 Oct 9.

21.

Effects of soluble β-amyloid on the release of neurotransmitters from rat brain synaptosomes.

Olivero G, Grilli M, Chen J, Preda S, Mura E, Govoni S, Marchi M.

Front Aging Neurosci. 2014 Jul 15;6:166. doi: 10.3389/fnagi.2014.00166. eCollection 2014.

22.

Autophagy is modulated in human neuroblastoma cells through direct exposition to low frequency electromagnetic fields.

Marchesi N, Osera C, Fassina L, Amadio M, Angeletti F, Morini M, Magenes G, Venturini L, Biggiogera M, Ricevuti G, Govoni S, Caorsi S, Pascale A, Comincini S.

J Cell Physiol. 2014 Nov;229(11):1776-86. doi: 10.1002/jcp.24631.

PMID:
24676932
23.

Clinical pharmacokinetics of morphine and its metabolites during morphine dose titration for chronic cancer pain.

De Gregori S, Minella CE, De Gregori M, Tinelli C, Ranzani GN, Govoni S, Allegri M, Regazzi M.

Ther Drug Monit. 2014 Jun;36(3):335-44. doi: 10.1097/FTD.0000000000000009.

PMID:
24595069
24.

Are Hsp70 protein expression and genetic polymorphism implicated in multiple sclerosis inflammation?

Boiocchi C, Osera C, Monti MC, Ferraro OE, Govoni S, Cuccia M, Montomoli C, Pascale A, Bergamaschi R.

J Neuroimmunol. 2014 Mar 15;268(1-2):84-8. doi: 10.1016/j.jneuroim.2014.01.004. Epub 2014 Jan 16.

PMID:
24485944
25.

Novel approaches to the post-myocardial infarction/heart failure neural remodeling.

D'Elia E, Pascale A, Marchesi N, Ferrero P, Senni M, Govoni S, Gronda E, Vanoli E.

Heart Fail Rev. 2014 Sep;19(5):611-9. doi: 10.1007/s10741-013-9415-6. Review.

PMID:
24292688
26.

Inhibitory effects of beta-amyloid on the nicotinic receptors which stimulate glutamate release in rat hippocampus: the glial contribution.

Salamone A, Mura E, Zappettini S, Grilli M, Olivero G, Preda S, Govoni S, Marchi M.

Eur J Pharmacol. 2014 Jan 15;723:314-21. doi: 10.1016/j.ejphar.2013.11.011. Epub 2013 Nov 23.

PMID:
24275353
27.

Pharmacological modulation of the state of awareness in patients with disorders of consciousness: an overview.

Mura E, Pistoia F, Sara M, Sacco S, Carolei A, Govoni S.

Curr Pharm Des. 2014;20(26):4121-39. Review.

PMID:
24025054
28.

Posttranscriptional regulation of SOD1 gene expression under oxidative stress: Potential role of ELAV proteins in sporadic ALS.

Milani P, Amadio M, Laforenza U, Dell'Orco M, Diamanti L, Sardone V, Gagliardi S, Govoni S, Ceroni M, Pascale A, Cereda C.

Neurobiol Dis. 2013 Dec;60:51-60. doi: 10.1016/j.nbd.2013.08.005. Epub 2013 Aug 20.

PMID:
23969235
29.

Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells.

Viiri J, Amadio M, Marchesi N, Hyttinen JM, Kivinen N, Sironen R, Rilla K, Akhtar S, Provenzani A, D'Agostino VG, Govoni S, Pascale A, Agostini H, Petrovski G, Salminen A, Kaarniranta K.

PLoS One. 2013 Jul 29;8(7):e69563. doi: 10.1371/journal.pone.0069563. Print 2013.

30.

Modulation of Rack-1/PKCβII signalling by soluble AβPPα in SH-SY5Y cells.

Buoso E, Biundo F, Lanni C, Aiello S, Grossi S, Schettini G, Govoni S, Racchi M.

Curr Alzheimer Res. 2013 Sep;10(7):697-705.

PMID:
23905995
31.

Dangerous liaisons between beta-amyloid and cholinergic neurotransmission.

Govoni S, Mura E, Preda S, Racchi M, Lanni C, Grilli M, Zappettini S, Salamone A, Olivero G, Pittaluga A, Marchi M.

Curr Pharm Des. 2014;20(15):2525-38. Review.

PMID:
23859550
32.

Genetic variability at COMT but not at OPRM1 and UGT2B7 loci modulates morphine analgesic response in acute postoperative pain.

De Gregori M, Garbin G, De Gregori S, Minella CE, Bugada D, Lisa A, Govoni S, Regazzi M, Allegri M, Ranzani GN.

Eur J Clin Pharmacol. 2013 Sep;69(9):1651-8. doi: 10.1007/s00228-013-1523-7. Epub 2013 May 19.

PMID:
23686330
33.

Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?

Mura E, Govoni S, Racchi M, Carossa V, Ranzani GN, Allegri M, van Schaik RH.

J Pain Res. 2013 May 1;6:331-53. doi: 10.2147/JPR.S42040. Print 2013.

34.

The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells.

Talman V, Amadio M, Osera C, Sorvari S, Boije Af Gennäs G, Yli-Kauhaluoma J, Rossi D, Govoni S, Collina S, Ekokoski E, Tuominen RK, Pascale A.

Pharmacol Res. 2013 Jul;73:44-54. doi: 10.1016/j.phrs.2013.04.008. Epub 2013 May 3.

PMID:
23643828
35.

Identification of peptides with ELAV-like mRNA-stabilizing effect: an integrated in vitro/in silico approach.

Amadio M, Pascale A, Govoni S, Laurini E, Pricl S, Gaggeri R, Rossi D, Collina S.

Chem Biol Drug Des. 2013 Jun;81(6):707-14. doi: 10.1111/cbdd.12117. Epub 2013 Apr 11.

PMID:
23398665
36.

Conformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression.

Buizza L, Prandelli C, Bonini SA, Delbarba A, Cenini G, Lanni C, Buoso E, Racchi M, Govoni S, Memo M, Uberti D.

Cell Death Dis. 2013 Feb 7;4:e484. doi: 10.1038/cddis.2013.13.

37.

Zyxin is a novel target for β-amyloid peptide: characterization of its role in Alzheimer's pathogenesis.

Lanni C, Necchi D, Pinto A, Buoso E, Buizza L, Memo M, Uberti D, Govoni S, Racchi M.

J Neurochem. 2013 Jun;125(5):790-9. doi: 10.1111/jnc.12154. Epub 2013 Feb 13.

38.

Do we need pharmacogenetics to personalize antidepressant therapy?

Lanni C, Racchi M, Govoni S.

Cell Mol Life Sci. 2013 Sep;70(18):3327-40. doi: 10.1007/s00018-012-1237-5. Epub 2012 Dec 28. Review.

PMID:
23272319
39.

Influence of COMT Val158Met polymorphism on Alzheimer's disease and mild cognitive impairment in Italian patients.

Lanni C, Garbin G, Lisa A, Biundo F, Ranzenigo A, Sinforiani E, Cuzzoni G, Govoni S, Ranzani GN, Racchi M.

J Alzheimers Dis. 2012;32(4):919-26. doi: 10.3233/JAD-2012-120358.

PMID:
22890094
40.
41.

Beta Amyloid Differently Modulate Nicotinic and Muscarinic Receptor Subtypes which Stimulate in vitro and in vivo the Release of Glycine in the Rat Hippocampus.

Zappettini S, Grilli M, Olivero G, Mura E, Preda S, Govoni S, Salamone A, Marchi M.

Front Pharmacol. 2012 Jul 27;3:146. doi: 10.3389/fphar.2012.00146. eCollection 2012.

42.

AβPP intracellular C-terminal domain function is related to its degradation processes.

Buoso E, Biundo F, Lanni C, Schettini G, Govoni S, Racchi M.

J Alzheimers Dis. 2012;30(2):393-405. doi: 10.3233/JAD-2012-111961.

PMID:
22451313
43.

Protecting the retinal neurons from glaucoma: lowering ocular pressure is not enough.

Pascale A, Drago F, Govoni S.

Pharmacol Res. 2012 Jul;66(1):19-32. doi: 10.1016/j.phrs.2012.03.002. Epub 2012 Mar 14. Review.

PMID:
22433276
44.

p53 at the crossroads between cancer and neurodegeneration.

Lanni C, Racchi M, Memo M, Govoni S, Uberti D.

Free Radic Biol Med. 2012 May 1;52(9):1727-33. doi: 10.1016/j.freeradbiomed.2012.02.034. Epub 2012 Mar 3. Review.

PMID:
22387179
45.

Dual effect of beta-amyloid on α7 and α4β2 nicotinic receptors controlling the release of glutamate, aspartate and GABA in rat hippocampus.

Mura E, Zappettini S, Preda S, Biundo F, Lanni C, Grilli M, Cavallero A, Olivero G, Salamone A, Govoni S, Marchi M.

PLoS One. 2012;7(1):e29661. doi: 10.1371/journal.pone.0029661. Epub 2012 Jan 11.

46.

Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease.

Buizza L, Cenini G, Lanni C, Ferrari-Toninelli G, Prandelli C, Govoni S, Buoso E, Racchi M, Barcikowska M, Styczynska M, Szybinska A, Butterfield DA, Memo M, Uberti D.

PLoS One. 2012;7(1):e29789. doi: 10.1371/journal.pone.0029789. Epub 2012 Jan 5.

47.

Pentraxins and Alzheimer's disease: at the interface between biomarkers and pharmacological targets.

Osera C, Pascale A, Amadio M, Venturini L, Govoni S, Ricevuti G.

Ageing Res Rev. 2012 Apr;11(2):189-98. doi: 10.1016/j.arr.2011.12.004. Epub 2011 Dec 15. Review.

PMID:
22186030
48.

The complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins.

Pascale A, Govoni S.

Cell Mol Life Sci. 2012 Feb;69(4):501-17. doi: 10.1007/s00018-011-0810-7. Epub 2011 Sep 10. Review.

PMID:
21909784
49.

Different presynaptic nicotinic receptor subtypes modulate in vivo and in vitro the release of glycine in the rat hippocampus.

Zappettini S, Mura E, Grilli M, Preda S, Salamone A, Olivero G, Govoni S, Marchi M.

Neurochem Int. 2011 Oct;59(5):729-38. doi: 10.1016/j.neuint.2011.06.022. Epub 2011 Jul 5.

PMID:
21762741
50.

Cytoprotective response induced by electromagnetic stimulation on SH-SY5Y human neuroblastoma cell line.

Osera C, Fassina L, Amadio M, Venturini L, Buoso E, Magenes G, Govoni S, Ricevuti G, Pascale A.

Tissue Eng Part A. 2011 Oct;17(19-20):2573-82. doi: 10.1089/ten.TEA.2011.0071. Epub 2011 Jul 5.

PMID:
21615217

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