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Items: 1 to 50 of 59

1.

Cryptococcal-related mortality despite fluconazole pre-emptive treatment in a cryptococcal antigen (CrAg) screen-and-treat programme.

Wake RM, Govender NP, Omar T, Nel C, Mazanderani AH, Karat AS, Ismail NA, Tiemessen CT, Jarvis JN, Harrison TS.

Clin Infect Dis. 2019 Jun 8. pii: ciz485. doi: 10.1093/cid/ciz485. [Epub ahead of print]

PMID:
31179488
2.

Essential in vitro diagnostics for advanced HIV and serious fungal diseases: international experts' consensus recommendations.

Bongomin F, Govender NP, Chakrabarti A, Robert-Gangneux F, Boulware DR, Zafar A, Oladele RO, Richardson MD, Gangneux JP, Alastruey-Izquierdo A, Bazira J, Boyles TH, Sarcarlal J, Nacher M, Obayashi T, Worodria W, Pasqualotto AC, Meya DB, Cheng B, Sriruttan C, Muzoora C, Kambugu A, Rodriguez Tudela JL, Jordan A, Chiller TM, Denning DW.

Eur J Clin Microbiol Infect Dis. 2019 Jun 7. doi: 10.1007/s10096-019-03600-4. [Epub ahead of print] No abstract available.

PMID:
31175479
3.

Cryptococcus neoformans: Diagnostic Dilemmas, Electron Microscopy and Capsular Variants.

Birkhead M, Naicker SD, Blasich NP, Rukasha I, Thomas J, Sriruttan C, Abrahams S, Mavuso GS, Govender NP.

Trop Med Infect Dis. 2018 Dec 20;4(1). pii: E1. doi: 10.3390/tropicalmed4010001.

4.

District and sub-district analysis of cryptococcal antigenaemia prevalence and specimen positivity in KwaZulu-Natal, South Africa.

Cassim N, Coetzee LM, Govender NP, Glencross DK.

Afr J Lab Med. 2018 Oct 11;7(1):757. doi: 10.4102/ajlm.v7i1.757. eCollection 2018.

5.

Candida auris in South Africa, 2012-2016.

Govender NP, Magobo RE, Mpembe R, Mhlanga M, Matlapeng P, Corcoran C, Govind C, Lowman W, Senekal M, Thomas J.

Emerg Infect Dis. 2018 Nov;24(11):2036-2040. doi: 10.3201/eid2411.180368.

6.

Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Methods.

Espinel-Ingroff A, Turnidge J, Alastruey-Izquierdo A, Botterel F, Canton E, Castro C, Chen YC, Chen Y, Chryssanthou E, Dannaoui E, Garcia-Effron G, Gonzalez GM, Govender NP, Guinea J, Kidd S, Lackner M, Lass-Flörl C, Linares-Sicilia MJ, López-Soria L, Magobo R, Pelaez T, Quindós G, Rodriguez-Iglesia MA, Ruiz MA, Sánchez-Reus F, Sanguinetti M, Shields R, Szweda P, Tortorano A, Wengenack NL, Bramati S, Cavanna C, DeLuca C, Gelmi M, Grancini A, Lombardi G, Meletiadis J, Negri CE, Passera M, Peman J, Prigitano A, Sala E, Tejada M.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01651-18. doi: 10.1128/AAC.01651-18. Print 2019 Jan.

7.

National coverage of reflex cryptococcal antigen screening: A milestone achievement in the care of persons with advanced HIV disease.

Govender NP, Glencross DK.

S Afr Med J. 2018 Jun 26;108(7):534-535. doi: 10.7196/SAMJ.2018.v108i7.13094. No abstract available.

8.

Large Outbreaks of Fungal and Bacterial Bloodstream Infections in a Neonatal Unit, South Africa, 2012-2016.

van Schalkwyk E, Iyaloo S, Naicker SD, Maphanga TG, Mpembe RS, Zulu TG, Mhlanga M, Mahlangu S, Maloba MB, Ntlemo G, Sanyane K, Mawela D, Govender NP.

Emerg Infect Dis. 2018 Jul;24(7):1204-1212. doi: 10.3201/eid2407.171087.

9.

Cryptococcal antigen positivity combined with the percentage of HIV-seropositive samples with CD4 counts <100 cells/μl identifies districts in South Africa with advanced burden of disease.

Coetzee LM, Cassim N, Sriruttan C, Mhlanga M, Govender NP, Glencross DK.

PLoS One. 2018 Jun 12;13(6):e0198993. doi: 10.1371/journal.pone.0198993. eCollection 2018.

10.

Brief Report: Point of Care Cryptococcal Antigen Screening: Pipetting Finger-Prick Blood Improves Performance of Immunomycologics Lateral Flow Assay.

Wake RM, Jarvis JN, Harrison TS, Govender NP.

J Acquir Immune Defic Syndr. 2018 Aug 15;78(5):574-578. doi: 10.1097/QAI.0000000000001721.

PMID:
29771787
11.

Paradoxical worsening of Emergomyces africanus infection in an HIV-infected male on itraconazole and antiretroviral therapy.

Crombie K, Spengane Z, Locketz M, Dlamini S, Lehloenya R, Wasserman S, Maphanga TG, Govender NP, Kenyon C, Schwartz IS.

PLoS Negl Trop Dis. 2018 Mar 8;12(3):e0006173. doi: 10.1371/journal.pntd.0006173. eCollection 2018 Mar. No abstract available.

12.

The Continuing Burden of Advanced HIV Disease Over 10 Years of Increasing Antiretroviral Therapy Coverage in South Africa.

Osler M, Hilderbrand K, Goemaere E, Ford N, Smith M, Meintjes G, Kruger J, Govender NP, Boulle A.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S118-S125. doi: 10.1093/cid/cix1140.

13.

Emergomyces africanus in Soil, South Africa.

Schwartz IS, Lerm B, Hoving JC, Kenyon C, Horsnell WG, Basson WJ, Otieno-Odhiambo P, Govender NP, Colebunders R, Botha A.

Emerg Infect Dis. 2018 Feb;24(2):377-380. doi: 10.3201/eid2402.171351.

14.

AIDS-Related Endemic Mycoses in Western Cape, South Africa, and Clinical Mimics: A Cross-Sectional Study of Adults With Advanced HIV and Recent-Onset, Widespread Skin Lesions.

Schwartz IS, Kenyon C, Lehloenya R, Claasens S, Spengane Z, Prozesky H, Burton R, Parker A, Wasserman S, Meintjes G, Mendelson M, Taljaard J, Schneider JW, Beylis N, Maloba B, Govender NP, Colebunders R, Dlamini S.

Open Forum Infect Dis. 2017 Aug 25;4(4):ofx186. doi: 10.1093/ofid/ofx186. eCollection 2017 Fall.

15.

High Cryptococcal Antigen Titers in Blood Are Predictive of Subclinical Cryptococcal Meningitis Among Human Immunodeficiency Virus-Infected Patients.

Wake RM, Britz E, Sriruttan C, Rukasha I, Omar T, Spencer DC, Nel JS, Mashamaite S, Adelekan A, Chiller TM, Jarvis JN, Harrison TS, Govender NP.

Clin Infect Dis. 2018 Feb 10;66(5):686-692. doi: 10.1093/cid/cix872.

16.

Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa.

Cronjé N, Schwartz IS, Retief L, Bastos ADS, Matthee S, Preiser W, Bennett NC, Maphanga T, Govender NP, Colebunders R, Kenyon C.

Med Mycol. 2018 Jun 1;56(4):510-513. doi: 10.1093/mmy/myx065.

PMID:
28992307
17.

First report of urease activity in the novel systemic fungal pathogen Emergomyces africanus: a comparison with the neurotrope Cryptococcus neoformans.

Lerm B, Kenyon C, Schwartz IS, Kroukamp H, de Witt R, Govender NP, de Hoog GS, Botha A.

FEMS Yeast Res. 2017 Nov 1;17(7). doi: 10.1093/femsyr/fox069.

PMID:
28934415
18.

A small proportion of community-associated methicillin-resistant Staphylococcus aureus bacteraemia, compared to healthcare-associated cases, in two South African provinces.

Perovic O, Singh-Moodley A, Govender NP, Kularatne R, Whitelaw A, Chibabhai V, Naicker P, Mbelle N, Lekalakala R, Quan V, Samuel C, Van Schalkwyk E; for GERMS-SA.

Eur J Clin Microbiol Infect Dis. 2017 Dec;36(12):2519-2532. doi: 10.1007/s10096-017-3096-3. Epub 2017 Aug 28.

PMID:
28849285
19.

Improvement of fungal disease identification and management: combined health systems and public health approaches.

Cole DC, Govender NP, Chakrabarti A, Sacarlal J, Denning DW.

Lancet Infect Dis. 2017 Dec;17(12):e412-e419. doi: 10.1016/S1473-3099(17)30308-0. Epub 2017 Jul 31. Review.

PMID:
28774694
20.

Multicenter, International Study of MIC/MEC Distributions for Definition of Epidemiological Cutoff Values for Sporothrix Species Identified by Molecular Methods.

Espinel-Ingroff A, Abreu DPB, Almeida-Paes R, Brilhante RSN, Chakrabarti A, Chowdhary A, Hagen F, Córdoba S, Gonzalez GM, Govender NP, Guarro J, Johnson EM, Kidd SE, Pereira SA, Rodrigues AM, Rozental S, Szeszs MW, Ballesté Alaniz R, Bonifaz A, Bonfietti LX, Borba-Santos LP, Capilla J, Colombo AL, Dolande M, Isla MG, Melhem MSC, Mesa-Arango AC, Oliveira MME, Panizo MM, Pires de Camargo Z, Zancope-Oliveira RM, Meis JF, Turnidge J.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e01057-17. doi: 10.1128/AAC.01057-17. Print 2017 Oct.

21.

Cryptococcal meningitis: A neglected NTD?

Molloy SF, Chiller T, Greene GS, Burry J, Govender NP, Kanyama C, Mfinanga S, Lesikari S, Mapoure YN, Kouanfack C, Sini V, Temfack E, Boulware DR, Dromer F, Denning DW, Day J, Stone NRH, Bicanic T, Jarvis JN, Lortholary O, Harrison TS, Jaffar S, Loyse A.

PLoS Negl Trop Dis. 2017 Jun 29;11(6):e0005575. doi: 10.1371/journal.pntd.0005575. eCollection 2017 Jun. No abstract available.

22.

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis.

Rajasingham R, Smith RM, Park BJ, Jarvis JN, Govender NP, Chiller TM, Denning DW, Loyse A, Boulware DR.

Lancet Infect Dis. 2017 Aug;17(8):873-881. doi: 10.1016/S1473-3099(17)30243-8. Epub 2017 May 5.

23.

In Vitro Antifungal Susceptibility of Yeast and Mold Phases of Isolates of Dimorphic Fungal Pathogen Emergomyces africanus (Formerly Emmonsia sp.) from HIV-Infected South African Patients.

Maphanga TG, Britz E, Zulu TG, Mpembe RS, Naicker SD, Schwartz IS, Govender NP.

J Clin Microbiol. 2017 Jun;55(6):1812-1820. doi: 10.1128/JCM.02524-16. Epub 2017 Mar 29.

24.

Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii.

Chen Y, Farrer RA, Giamberardino C, Sakthikumar S, Jones A, Yang T, Tenor JL, Wagih O, Van Wyk M, Govender NP, Mitchell TG, Litvintseva AP, Cuomo CA, Perfect JR.

MBio. 2017 Mar 7;8(2). pii: e00166-17. doi: 10.1128/mBio.00166-17.

25.

Novel taxa of thermally dimorphic systemic pathogens in the Ajellomycetaceae (Onygenales).

Dukik K, Muñoz JF, Jiang Y, Feng P, Sigler L, Stielow JB, Freeke J, Jamalian A, Gerrits van den Ende B, McEwen JG, Clay OK, Schwartz IS, Govender NP, Maphanga TG, Cuomo CA, Moreno LF, Kenyon C, Borman AM, de Hoog S.

Mycoses. 2017 May;60(5):296-309. doi: 10.1111/myc.12601. Epub 2017 Feb 7.

26.

Looking for fungi in all the right places: screening for cryptococcal disease and other AIDS-related mycoses among patients with advanced HIV disease.

Greene G, Sriruttan C, Le T, Chiller T, Govender NP.

Curr Opin HIV AIDS. 2017 Mar;12(2):139-147. doi: 10.1097/COH.0000000000000347. Review.

PMID:
28134711
27.

Detection of neonatal unit clusters of Candida parapsilosis fungaemia by microsatellite genotyping: Results from laboratory-based sentinel surveillance, South Africa, 2009-2010.

Magobo RE, Naicker SD, Wadula J, Nchabeleng M, Coovadia Y, Hoosen A, Lockhart SR, Govender NP; TRAC-South Africa group.

Mycoses. 2017 May;60(5):320-327. doi: 10.1111/myc.12596. Epub 2017 Jan 19.

PMID:
28101934
28.

Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses.

Lockhart SR, Etienne KA, Vallabhaneni S, Farooqi J, Chowdhary A, Govender NP, Colombo AL, Calvo B, Cuomo CA, Desjardins CA, Berkow EL, Castanheira M, Magobo RE, Jabeen K, Asghar RJ, Meis JF, Jackson B, Chiller T, Litvintseva AP.

Clin Infect Dis. 2017 Jan 15;64(2):134-140. doi: 10.1093/cid/ciw691. Epub 2016 Oct 20.

29.

Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method.

Espinel-Ingroff A, Arendrup M, Cantón E, Cordoba S, Dannaoui E, García-Rodríguez J, Gonzalez GM, Govender NP, Martin-Mazuelos E, Lackner M, Lass-Flörl C, Linares Sicilia MJ, Rodriguez-Iglesias MA, Pelaez T, Shields RK, Garcia-Effron G, Guinea J, Sanguinetti M, Turnidge J.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e01792-16. doi: 10.1128/AAC.01792-16. Print 2017 Jan.

30.

The Epidemiology of Meningitis among Adults in a South African Province with a High HIV Prevalence, 2009-2012.

Britz E, Perovic O, von Mollendorf C, von Gottberg A, Iyaloo S, Quan V, Chetty V, Sriruttan C, Ismail NA, Nanoo A, Musekiwa A, Reddy C, Viljoen K, Cohen C, Govender NP.

PLoS One. 2016 Sep 26;11(9):e0163036. doi: 10.1371/journal.pone.0163036. eCollection 2016.

31.

Prevalence and Hospital Management of Amphotericin B Deoxycholate-Related Toxicities during Treatment of HIV-Associated Cryptococcal Meningitis in South Africa.

Meiring S, Fortuin-de Smidt M, Kularatne R, Dawood H, Govender NP; GERMS-SA.

PLoS Negl Trop Dis. 2016 Jul 28;10(7):e0004865. doi: 10.1371/journal.pntd.0004865. eCollection 2016 Jul.

32.

Screening HIV-Infected Patients with Low CD4 Counts for Cryptococcal Antigenemia prior to Initiation of Antiretroviral Therapy: Cost Effectiveness of Alternative Screening Strategies in South Africa.

Larson BA, Rockers PC, Bonawitz R, Sriruttan C, Glencross DK, Cassim N, Coetzee LM, Greene GS, Chiller TM, Vallabhaneni S, Long L, van Rensburg C, Govender NP.

PLoS One. 2016 Jul 8;11(7):e0158986. doi: 10.1371/journal.pone.0158986. eCollection 2016.

33.

Comparison of species-level identification and antifungal susceptibility results from diagnostic and reference laboratories for bloodstream Candida surveillance isolates, South Africa, 2009-2010.

Naicker SD, Govender N, Patel J, Zietsman IL, Wadula J, Coovadia Y, Kularatne R, Seetharam S, Govender NP; TRAC-SA group.

Med Mycol. 2016 Nov 1;54(8):816-24. doi: 10.1093/mmy/myw046. Epub 2016 Jun 22.

PMID:
27335055
34.

Emergence of azole-resistant Candida parapsilosis causing bloodstream infection: results from laboratory-based sentinel surveillance in South Africa.

Govender NP, Patel J, Magobo RE, Naicker S, Wadula J, Whitelaw A, Coovadia Y, Kularatne R, Govind C, Lockhart SR, Zietsman IL; TRAC-South Africa group.

J Antimicrob Chemother. 2016 Jul;71(7):1994-2004. doi: 10.1093/jac/dkw091. Epub 2016 Apr 28.

PMID:
27125552
35.

Two echinocandin-resistant Candida glabrata FKS mutants from South Africa.

Naicker SD, Magobo RE, Zulu TG, Maphanga TG, Luthuli N, Lowman W, Govender NP.

Med Mycol Case Rep. 2016 Mar 21;11:24-6. doi: 10.1016/j.mmcr.2016.03.004. eCollection 2016 Mar.

36.

Implementation and Operational Research: Evaluation of a Public-Sector, Provider-Initiated Cryptococcal Antigen Screening and Treatment Program, Western Cape, South Africa.

Vallabhaneni S, Longley N, Smith M, Smith R, Osler M, Kelly N, Cross A, Boulle A, Meintjes G, Govender NP.

J Acquir Immune Defic Syndr. 2016 Jun 1;72(2):e37-e42. doi: 10.1097/QAI.0000000000000976.

37.

50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens.

Schwartz IS, Kenyon C, Feng P, Govender NP, Dukik K, Sigler L, Jiang Y, Stielow JB, Muñoz JF, Cuomo CA, Botha A, Stchigel AM, de Hoog GS.

PLoS Pathog. 2015 Nov 19;11(11):e1005198. doi: 10.1371/journal.ppat.1005198. eCollection 2015. Review. No abstract available.

38.

Cryptococcal Antigen Screening in Patients Initiating ART in South Africa: A Prospective Cohort Study.

Longley N, Jarvis JN, Meintjes G, Boulle A, Cross A, Kelly N, Govender NP, Bekker LG, Wood R, Harrison TS.

Clin Infect Dis. 2016 Mar 1;62(5):581-587. doi: 10.1093/cid/civ936. Epub 2015 Nov 12.

39.

Cryptococcal antigen screening in HIV-infected adults: let's get straight to the point.

Wake RM, Glencross DK, Sriruttan C, Harrison TS, Govender NP.

AIDS. 2016 Jan 28;30(3):339-42. doi: 10.1097/QAD.0000000000000967. No abstract available.

PMID:
26558733
40.

Evidence of genotypic diversity among Candida auris isolates by multilocus sequence typing, matrix-assisted laser desorption ionization time-of-flight mass spectrometry and amplified fragment length polymorphism.

Prakash A, Sharma C, Singh A, Kumar Singh P, Kumar A, Hagen F, Govender NP, Colombo AL, Meis JF, Chowdhary A.

Clin Microbiol Infect. 2016 Mar;22(3):277.e1-9. doi: 10.1016/j.cmi.2015.10.022. Epub 2015 Nov 5.

41.

An Outbreak of Lymphocutaneous Sporotrichosis among Mine-Workers in South Africa.

Govender NP, Maphanga TG, Zulu TG, Patel J, Walaza S, Jacobs C, Ebonwu JI, Ntuli S, Naicker SD, Thomas J.

PLoS Negl Trop Dis. 2015 Sep 25;9(9):e0004096. doi: 10.1371/journal.pntd.0004096. eCollection 2015 Sep.

42.

Access to flucytosine for HIV-infected patients with cryptococcal meningitis – an urgent need.

Govender NP, Meintjes G, Banoo S.

S Afr Med J. 2014 Sep;104(9):594-5. No abstract available.

PMID:
26307779
43.

Multicenter study of epidemiological cutoff values and detection of resistance in Candida spp. to anidulafungin, caspofungin, and micafungin using the Sensititre YeastOne colorimetric method.

Espinel-Ingroff A, Alvarez-Fernandez M, Cantón E, Carver PL, Chen SC, Eschenauer G, Getsinger DL, Gonzalez GM, Govender NP, Grancini A, Hanson KE, Kidd SE, Klinker K, Kubin CJ, Kus JV, Lockhart SR, Meletiadis J, Morris AJ, Pelaez T, Quindós G, Rodriguez-Iglesias M, Sánchez-Reus F, Shoham S, Wengenack NL, Borrell Solé N, Echeverria J, Esperalba J, Gómez-G de la Pedrosa E, García García I, Linares MJ, Marco F, Merino P, Pemán J, Pérez Del Molino L, Roselló Mayans E, Rubio Calvo C, Ruiz Pérez de Pipaon M, Yagüe G, Garcia-Effron G, Guinea J, Perlin DS, Sanguinetti M, Shields R, Turnidge J.

Antimicrob Agents Chemother. 2015 Nov;59(11):6725-32. doi: 10.1128/AAC.01250-15. Epub 2015 Aug 17.

44.

Clinical Characteristics, Diagnosis, Management, and Outcomes of Disseminated Emmonsiosis: A Retrospective Case Series.

Schwartz IS, Govender NP, Corcoran C, Dlamini S, Prozesky H, Burton R, Mendelson M, Taljaard J, Lehloenya R, Calligaro G, Colebunders R, Kenyon C.

Clin Infect Dis. 2015 Sep 15;61(6):1004-12. doi: 10.1093/cid/civ439. Epub 2015 Jun 9.

PMID:
26060283
45.

A case of emmonsiosis in an HIV-infected child.

Lochan H, Naicker P, Maphanga T, Ryan A, Pillay K, Govender NP, Eley B.

South Afr J HIV Med. 2015 Jun 11;16(1):352. doi: 10.4102/sajhivmed.v16i1.352. eCollection 2015.

46.

Evaluation of screening and treatment of cryptococcal antigenaemia among HIV-infected persons in Soweto, South Africa.

Govender NP, Roy M, Mendes JF, Zulu TG, Chiller TM, Karstaedt AS.

HIV Med. 2015 Sep;16(8):468-76. doi: 10.1111/hiv.12245. Epub 2015 Feb 17.

47.

Staphylococcus aureus bacteraemia in Gauteng academic hospitals, South Africa.

Fortuin-de Smidt MC, Singh-Moodley A, Badat R, Quan V, Kularatne R, Nana T, Lekalakala R, Govender NP, Perovic O; for GERMS-SA.

Int J Infect Dis. 2015 Jan;30:41-8. doi: 10.1016/j.ijid.2014.10.011. Epub 2014 Oct 30.

48.

HIV-associated disseminated emmonsiosis, Johannesburg, South Africa.

van Hougenhouck-Tulleken WG, Papavarnavas NS, Nel JS, Blackburn LY, Govender NP, Spencer DC, Lippincott CK.

Emerg Infect Dis. 2014 Dec;20(12):2164-6. doi: 10.3201/eid2012.140902. No abstract available.

49.

Candida auris-associated candidemia, South Africa.

Magobo RE, Corcoran C, Seetharam S, Govender NP.

Emerg Infect Dis. 2014 Jul;20(7):1250-1. doi: 10.3201/eid2007.131765. No abstract available.

50.

Very low levels of 25-hydroxyvitamin D are not associated with immunologic changes or clinical outcome in South African patients with HIV-associated cryptococcal meningitis.

Jarvis JN, Bicanic T, Loyse A, Meintjes G, Hogan L, Roberts CH, Shoham S, Perfect JR, Govender NP, Harrison TS.

Clin Infect Dis. 2014 Aug 15;59(4):493-500. doi: 10.1093/cid/ciu349. Epub 2014 May 13.

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