Sort by
Items per page

Send to

Choose Destination

Search results

Items: 28


Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade.

Shekarian T, Sivado E, Jallas AC, Depil S, Kielbassa J, Janoueix-Lerosey I, Hutter G, Goutagny N, Bergeron C, Viari A, Valsesia-Wittmann S, Caux C, Marabelle A.

Sci Transl Med. 2019 Oct 23;11(515). pii: eaat5025. doi: 10.1126/scitranslmed.aat5025.


Performance characteristics of the VIDAS® ANTI-HEV IgM and IgG assays.

Abravanel F, Goutagny N, Joffray R, Eichenlaub E, Baron S, Aversenq A, Bourg S, Mercier L, Larue Triolet A, Poirault D, Loubet M, Daniel S, Luciani F, Pothion C, Tourneur C, Dugua JM, Lhomme S, Izopet J.

J Clin Virol. 2019 Mar;112:10-14. doi: 10.1016/j.jcv.2019.01.005. Epub 2019 Jan 11.


Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.

Ainouze M, Rochefort P, Parroche P, Roblot G, Tout I, Briat F, Zannetti C, Marotel M, Goutagny N, Auron P, Traverse-Glehen A, Lunel-Potencier A, Golfier F, Masson M, Robitaille A, Tommasino M, Carreira C, Walzer T, Henry T, Zanier K, Trave G, Hasan UA.

PLoS Pathog. 2018 Aug 8;14(8):e1007158. doi: 10.1371/journal.ppat.1007158. eCollection 2018 Aug.


Evaluation of two VIDAS ®prototypes for detecting anti-HEV IgG.

Abravanel F, Goutagny N, Perret C, Lhomme S, Vischi F, Aversenq A, Chapel A, Dehainault N, Piga N, Dupret-Carruel J, Izopet J.

J Clin Virol. 2017 Apr;89:46-50. doi: 10.1016/j.jcv.2017.02.009. Epub 2017 Feb 24.


TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expression.

Parroche P, Roblot G, Le Calvez-Kelm F, Tout I, Marotel M, Malfroy M, Durand G, McKay J, Ainouze M, Carreira C, Allatif O, Traverse-Glehen A, Mendiola M, Pozo-Kreilinger JJ, Caux C, Tommasino M, Goutagny N, Hasan UA.

Oncogenesis. 2016 Jul 25;5(7):e244. doi: 10.1038/oncsis.2016.49.


Human natural killer cells promote cross-presentation of tumor cell-derived antigens by dendritic cells.

Deauvieau F, Ollion V, Doffin AC, Achard C, Fonteneau JF, Verronese E, Durand I, Ghittoni R, Marvel J, Dezutter-Dambuyant C, Walzer T, Vie H, Perrot I, Goutagny N, Caux C, Valladeau-Guilemond J.

Int J Cancer. 2015 Mar 1;136(5):1085-94. doi: 10.1002/ijc.29087. Epub 2014 Aug 6.


The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter.

Hasan UA, Zannetti C, Parroche P, Goutagny N, Malfroy M, Roblot G, Carreira C, Hussain I, Müller M, Taylor-Papadimitriou J, Picard D, Sylla BS, Trinchieri G, Medzhitov R, Tommasino M.

J Exp Med. 2013 Jul 1;210(7):1369-87. doi: 10.1084/jem.20122394. Epub 2013 Jun 10.


Tumor promotion by intratumoral plasmacytoid dendritic cells is reversed by TLR7 ligand treatment.

Le Mercier I, Poujol D, Sanlaville A, Sisirak V, Gobert M, Durand I, Dubois B, Treilleux I, Marvel J, Vlach J, Blay JY, Bendriss-Vermare N, Caux C, Puisieux I, Goutagny N.

Cancer Res. 2013 Aug 1;73(15):4629-40. doi: 10.1158/0008-5472.CAN-12-3058. Epub 2013 May 30.


Breast cancer-derived transforming growth factor-β and tumor necrosis factor-α compromise interferon-α production by tumor-associated plasmacytoid dendritic cells.

Sisirak V, Vey N, Goutagny N, Renaudineau S, Malfroy M, Thys S, Treilleux I, Labidi-Galy SI, Bachelot T, Dezutter-Dambuyant C, Ménétrier-Caux C, Blay JY, Caux C, Bendriss-Vermare N.

Int J Cancer. 2013 Aug 1;133(3):771-8. doi: 10.1002/ijc.28072. Epub 2013 Mar 8.


Impaired IFN-α production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression.

Sisirak V, Faget J, Gobert M, Goutagny N, Vey N, Treilleux I, Renaudineau S, Poyet G, Labidi-Galy SI, Goddard-Leon S, Durand I, Le Mercier I, Bajard A, Bachelot T, Puisieux A, Puisieux I, Blay JY, Ménétrier-Caux C, Caux C, Bendriss-Vermare N.

Cancer Res. 2012 Oct 15;72(20):5188-97. doi: 10.1158/0008-5472.CAN-11-3468. Epub 2012 Jul 25.


Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling.

Paquette N, Conlon J, Sweet C, Rus F, Wilson L, Pereira A, Rosadini CV, Goutagny N, Weber AN, Lane WS, Shaffer SA, Maniatis S, Fitzgerald KA, Stuart L, Silverman N.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12710-5. doi: 10.1073/pnas.1008203109. Epub 2012 Jul 16.


Targeting pattern recognition receptors in cancer immunotherapy.

Goutagny N, Estornes Y, Hasan U, Lebecque S, Caux C.

Target Oncol. 2012 Mar;7(1):29-54. doi: 10.1007/s11523-012-0213-1. Epub 2012 Mar 8. Review.


Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner.

Perret M, Badiou C, Lina G, Burbaud S, Benito Y, Bes M, Cottin V, Couzon F, Juruj C, Dauwalder O, Goutagny N, Diep BA, Vandenesch F, Henry T.

Cell Microbiol. 2012 Jul;14(7):1019-36. doi: 10.1111/j.1462-5822.2012.01772.x. Epub 2012 Mar 5.


Early detection of tumor cells by innate immune cells leads to T(reg) recruitment through CCL22 production by tumor cells.

Faget J, Biota C, Bachelot T, Gobert M, Treilleux I, Goutagny N, Durand I, Léon-Goddard S, Blay JY, Caux C, Ménétrier-Caux C.

Cancer Res. 2011 Oct 1;71(19):6143-52. doi: 10.1158/0008-5472.CAN-11-0573. Epub 2011 Aug 18.


Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.

Sharma S, DeOliveira RB, Kalantari P, Parroche P, Goutagny N, Jiang Z, Chan J, Bartholomeu DC, Lauw F, Hall JP, Barber GN, Gazzinelli RT, Fitzgerald KA, Golenbock DT.

Immunity. 2011 Aug 26;35(2):194-207. doi: 10.1016/j.immuni.2011.05.016. Epub 2011 Aug 4.


Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.

Marchlik E, Thakker P, Carlson T, Jiang Z, Ryan M, Marusic S, Goutagny N, Kuang W, Askew GR, Roberts V, Benoit S, Zhou T, Ling V, Pfeifer R, Stedman N, Fitzgerald KA, Lin LL, Hall JP.

J Leukoc Biol. 2010 Dec;88(6):1171-80. doi: 10.1189/jlb.0210071. Epub 2010 Jul 22.


Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.

Goutagny N, Jiang Z, Tian J, Parroche P, Schickli J, Monks BG, Ulbrandt N, Ji H, Kiener PA, Coyle AJ, Fitzgerald KA.

J Immunol. 2010 Feb 1;184(3):1168-79. doi: 10.4049/jimmunol.0902750. Epub 2009 Dec 30.


Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.

Ablasser A, Poeck H, Anz D, Berger M, Schlee M, Kim S, Bourquin C, Goutagny N, Jiang Z, Fitzgerald KA, Rothenfusser S, Endres S, Hartmann G, Hornung V.

J Immunol. 2009 Jun 1;182(11):6824-33. doi: 10.4049/jimmunol.0803001.


Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling.

Geeraedts F, Goutagny N, Hornung V, Severa M, de Haan A, Pool J, Wilschut J, Fitzgerald KA, Huckriede A.

PLoS Pathog. 2008 Aug 29;4(8):e1000138. doi: 10.1371/journal.ppat.1000138.


The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.

Roberts ZJ, Goutagny N, Perera PY, Kato H, Kumar H, Kawai T, Akira S, Savan R, van Echo D, Fitzgerald KA, Young HA, Ching LM, Vogel SN.

J Exp Med. 2007 Jul 9;204(7):1559-69. Epub 2007 Jun 11.


Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

Parroche P, Lauw FN, Goutagny N, Latz E, Monks BG, Visintin A, Halmen KA, Lamphier M, Olivier M, Bartholomeu DC, Gazzinelli RT, Golenbock DT.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1919-24. Epub 2007 Jan 29.


Pattern recognition receptors: an update.

Goutagny N, Fitzgerald KA.

Expert Rev Clin Immunol. 2006 Jul;2(4):569-83. doi: 10.1586/1744666X.2.4.569.


Pin-ning down immune responses to RNA viruses.

Goutagny N, Severa M, Fitzgerald KA.

Nat Immunol. 2006 Jun;7(6):555-7. No abstract available.


The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA.

J Immunol. 2005 Oct 15;175(8):5260-8.


The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.

Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM, Fitzgerald KA, Golenbock DT.

J Biol Chem. 2005 Apr 29;280(17):17005-12. Epub 2005 Jan 28.


Stimulation of Fas agonistic antibody-mediated apoptosis by heparin-like agents suppresses Hsp27 but not Bcl-2 protective activity.

Manero F, Ljubic-Thibal V, Moulin M, Goutagny N, Yvin JC, Arrigo AP.

Cell Stress Chaperones. 2004 Summer;9(2):150-66.


Quantification and functional analysis of plasmacytoid dendritic cells in patients with chronic hepatitis C virus infection.

Goutagny N, Vieux C, Decullier E, Ligeoix B, Epstein A, Trepo C, Couzigou P, Inchauspe G, Bain C.

J Infect Dis. 2004 May 1;189(9):1646-55. Epub 2004 Apr 15.


Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection.

Goutagny N, Fatmi A, De Ledinghen V, Penin F, Couzigou P, Inchauspé G, Bain C.

J Infect Dis. 2003 Jun 15;187(12):1951-8. Epub 2003 May 29.


Supplemental Content

Loading ...
Support Center