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Comparative effectiveness of teriflunomide vs dimethyl fumarate in multiple sclerosis.

Laplaud DA, Casey R, Barbin L, Debouverie M, De Sèze J, Brassat D, Wiertlewski S, Brochet B, Pelletier J, Vermersch P, Edan G, Lebrun-Frenay C, Clavelou P, Thouvenot E, Camdessanché JP, Tourbah A, Stankoff B, Al Khedr A, Cabre P, Lubetzki C, Papeix C, Berger E, Heinzlef O, Debroucker T, Moreau T, Gout O, Bourre B, Wahab A, Labauge P, Magy L, Defer G, Guennoc AM, Maubeuge N, Labeyrie C, Patry I, Nifle C, Casez O, Michel L, Rollot F, Leray E, Vukusic S, Foucher Y; SFSEP and OFSEP groups.

Neurology. 2019 Jul 12. pii: 10.1212/WNL.0000000000007938. doi: 10.1212/WNL.0000000000007938. [Epub ahead of print]


Diagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal Enhancement.

Coulette S, Lecler A, Saragoussi E, Zuber K, Savatovsky J, Deschamps R, Gout O, Sabben C, Aboab J, Affortit A, Charbonneau F, Obadia M.

AJNR Am J Neuroradiol. 2019 Jul;40(7):1184-1190. doi: 10.3174/ajnr.A6103. Epub 2019 Jun 27.


Improving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3T.

Lecler A, El Sanharawi I, El Methni J, Gout O, Koskas P, Savatovsky J.

AJNR Am J Neuroradiol. 2019 Jul;40(7):1170-1176. doi: 10.3174/ajnr.A6107. Epub 2019 Jun 27.


MRI features of demyelinating disease associated with anti-MOG antibodies in adults.

Denève M, Biotti D, Patsoura S, Ferrier M, Meluchova Z, Mahieu L, Heran F, Vignal C, Deschamps R, Gout O, Champfleur NM, Ayrignac X, Dallière CC, Labauge P, Dulau C, Tourdias T, Dumas H, Cognard C, Brassat D, Bonneville F.

J Neuroradiol. 2019 Jun 20. pii: S0150-9861(19)30304-9. doi: 10.1016/j.neurad.2019.06.001. [Epub ahead of print] Review.


Tonic spinal cord stimulation as therapeutic option in Parkinson disease with axial symptoms: Effects on walking and quality of life.

Hubsch C, D'Hardemare V, Ben Maacha M, Ziegler M, Patte-Karsenti N, Thiebaut JB, Gout O, Brandel JP.

Parkinsonism Relat Disord. 2019 Mar 2. pii: S1353-8020(19)30090-2. doi: 10.1016/j.parkreldis.2019.02.044. [Epub ahead of print]


A new association: acute macular neuroretinopathy in acute optic neuritis.

Deschamps R, Vasseur V, Shor N, Vignal C, Salomon L, Gout O, Mauget-Faÿsse M.

Acta Ophthalmol. 2019 Aug;97(5):e753-e756. doi: 10.1111/aos.14054. Epub 2019 Feb 13.


A 3T Phase-Sensitive Inversion Recovery MRI Sequence Improves Detection of Cervical Spinal Cord Lesions and Shows Active Lesions in Patients with Multiple Sclerosis.

Fechner A, Savatovsky J, El Methni J, Sadik JC, Gout O, Deschamps R, Gueguen A, Lecler A.

AJNR Am J Neuroradiol. 2019 Feb;40(2):370-375. doi: 10.3174/ajnr.A5941. Epub 2019 Jan 24.


Should we treat patients with radiologically isolated syndrome (RIS)? No.

Gout O.

Rev Neurol (Paris). 2018 Dec;174(10):693-695. doi: 10.1016/j.neurol.2018.05.002. Epub 2018 Nov 16. No abstract available.


Anxiety and depression in patients with multiple sclerosis: The mediating effects of perceived social support.

Henry A, Tourbah A, Camus G, Deschamps R, Mailhan L, Castex C, Gout O, Montreuil M.

Mult Scler Relat Disord. 2019 Jan;27:46-51. doi: 10.1016/j.msard.2018.09.039. Epub 2018 Oct 2.


Inaugural tumor-like multiple sclerosis: clinical presentation and medium-term outcome in 87 patients.

Balloy G, Pelletier J, Suchet L, Lebrun C, Cohen M, Vermersch P, Zephir H, Duhin E, Gout O, Deschamps R, Le Page E, Edan G, Labauge P, Carra-Dallieres C, Rumbach L, Berger E, Lejeune P, Devos P, N'Kendjuo JB, Coustans M, Auffray-Calvier E, Daumas-Duport B, Michel L, Lefrere F, Laplaud DA, Brosset C, Derkinderen P, de Seze J, Wiertlewski S; Société Francophone de la Sclérose en Plaques.

J Neurol. 2018 Oct;265(10):2251-2259. doi: 10.1007/s00415-018-8984-7. Epub 2018 Jul 27.


Acute idiopathic optic neuritis: not always benign.

Deschamps R, Gueguen A, Lecler A, Lecouturier K, Lamirel C, Bensa C, Marignier R, Vignal C, Gout O.

Eur J Neurol. 2018 Nov;25(11):1378-1383. doi: 10.1111/ene.13753. Epub 2018 Aug 16.


Improved Detection of New MS Lesions during Follow-Up Using an Automated MR Coregistration-Fusion Method.

Galletto Pregliasco A, Collin A, Guéguen A, Metten MA, Aboab J, Deschamps R, Gout O, Duron L, Sadik JC, Savatovsky J, Lecler A.

AJNR Am J Neuroradiol. 2018 Jul;39(7):1226-1232. doi: 10.3174/ajnr.A5690. Epub 2018 Jun 7.


MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study.

Tourbah A, Gout O, Vighetto A, Deburghgraeve V, Pelletier J, Papeix C, Lebrun-Frenay C, Labauge P, Brassat D, Toosy A, Laplaud DA, Outteryck O, Moreau T, Debouverie M, Clavelou P, Heinzlef O, De Sèze J, Defer G, Sedel F, Arndt C.

CNS Drugs. 2018 Jul;32(7):661-672. doi: 10.1007/s40263-018-0528-2.


Are we missing patients with biotinidase deficiency in France?

Deschamps R, Stankoff B, Vignal C, Benoist JF, Wolf B, Gout O.

Rev Neurol (Paris). 2018 May;174(5):273-274. doi: 10.1016/j.neurol.2017.11.007. No abstract available.


Efficacy of rituximab in refractory RRMS.

Durozard P, Maarouf A, Boutiere C, Ruet A, Brochet B, Vukusic S, Carra-Dalliere C, Labauge P, Mathey G, Debouverie M, Papeix C, Maillart E, Lubetzki C, Bensa C, Gout O, Giannesini C, Stankoff B, Ciron J, Brassat D, Pelletier J, Rico Lamy A, Audoin B.

Mult Scler. 2019 May;25(6):828-836. doi: 10.1177/1352458518772748. Epub 2018 May 3.


Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection.

Jeannin P, Chaze T, Giai Gianetto Q, Matondo M, Gout O, Gessain A, Afonso PV.

Sci Rep. 2018 Mar 26;8(1):5170. doi: 10.1038/s41598-018-23505-0.


Orolingual and abdominal angioedema post thrombolysis and thrombectomy.

Benoit C, Cantier M, Rodriguez-Régent C, Gout O, Obadia M.

Neurology. 2018 Jan 16;90(3):140-141. doi: 10.1212/WNL.0000000000004834. No abstract available.


Rituximab for corticosteroid-resistant relapsing IgG4-related intracranial pachymeningitis: report of two cases.

Mageau A, Shor N, Fisselier M, Aboab J, Lecler A, Rebours C, Adle-Biassette H, Gout O, Deschamps R.

Pract Neurol. 2018 Apr;18(2):159-161. doi: 10.1136/practneurol-2017-001826. Epub 2017 Dec 5.


Treating asymptomatic bacteriuria before immunosuppressive therapy during multiple sclerosis: Should we do it?

Rouzaud C, Hautecoeur P, Donze C, Heinzlef O, Dinh A; Club Francophone de la Sclérose en Plaque, Creange A, Abdullatif A, Audouin B, Tourbah A, Berger E, Bourre B, Brochet B, Mekies C, Cabre P, Papeix C, Casez O, Brassat D, Defer G, Derache N, De Seze J, Dive D, LePage E, Fromont A, Gouider R, Edan G, Pelletier J, Grimaud J, Guennoc AM, Camdessanché JP, Kwiatkowski A, Laplaud D, Lebrun C, Debouverie M, Coustans M, Gout O, La Rochelle OA, Heinzlef O, Ouallet JC, Cavelou P, Hautecoeur P, Labauge P, Vermersch P, Wiertlewski S, Vukusic S, Marignier R, Schluep M, Seeldrayers P, Slassi I, Stankoff B, Thaite F, Moreau T, Thouvenot E, Zephir H, Ciron J, Collongues N, Kerschen P, Cohen M, Gueguen A, Mathey G, Carra C, Bernady P, Faucheux JM, Planque E, Donze C, Ruet A, Mouzawakh C, Pittion S.

Mult Scler Relat Disord. 2017 Nov;18:161-163. doi: 10.1016/j.msard.2017.08.009. Epub 2017 Aug 24. No abstract available.


Central nervous system Aquaporin4 autoimmunity revealed by a single pseudotumoral encephalic lesion.

Fargeot G, Aboab J, Savatovsky J, Marignier R, Lecler A, Gout O.

Metab Brain Dis. 2018 Feb;33(1):353-355. doi: 10.1007/s11011-017-0141-y. Epub 2017 Oct 31.


Adult-onset biotinidase deficiency: two individuals with severe, but reversible optic neuropathy.

Deschamps R, Savatovsky J, Vignal C, Fisselier M, Imbard A, Wolf B, Procter M, Gout O.

J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):1009-1010. doi: 10.1136/jnnp-2017-316644. Epub 2017 Oct 12. No abstract available.


Optic neuritis in patients with anti-MOG antibodies spectrum disorder: MRI and clinical features from a large multicentric cohort in France.

Biotti D, Bonneville F, Tournaire E, Ayrignac X, Dallière CC, Mahieu L, Vignal C, Dulau C, Brochet B, Ruet A, Ouallet JC, Gout O, Heran F, Menjot de Champfleur N, Tourdias T, Deneve M, Labauge P, Deschamps R.

J Neurol. 2017 Oct;264(10):2173-2175. doi: 10.1007/s00415-017-8615-8. Epub 2017 Sep 15. No abstract available.


Reply to "Axonal hyperexcitability due to Schwann cell involvement in chronic progressive external ophthalmoplegia".

Guéguen A, Jardel C, Polivka M, Tan SV, Gray F, Vignal C, Lombès A, Gout O, Bostock H.

Clin Neurophysiol. 2017 Oct;128(10):2098. doi: 10.1016/j.clinph.2017.07.407. Epub 2017 Jul 31. No abstract available.


HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation.

Percher F, Curis C, Pérès E, Artesi M, Rosewick N, Jeannin P, Gessain A, Gout O, Mahieux R, Ceccaldi PE, Van den Broeke A, Duc Dodon M, Afonso PV.

Nat Commun. 2017 Jun 22;8:15890. doi: 10.1038/ncomms15890.


Erratum to: Plasma exchange response in 34 patients with severe optic neuritis.

Deschamps R, Gueguen A, Parquet N, Saheb S, Driss F, Mesnil M, Vignal C, Aboab J, Depaz R, Gout O.

J Neurol. 2017 Jul;264(7):1547. doi: 10.1007/s00415-017-8534-8. No abstract available.


Nerve excitability changes related to muscle weakness in chronic progressive external ophthalmoplegia.

Gueguen A, Jardel C, Polivka M, Tan SV, Gray F, Vignal C, Lombès A, Gout O, Bostock H.

Clin Neurophysiol. 2017 Jul;128(7):1258-1263. doi: 10.1016/j.clinph.2017.04.013. Epub 2017 Apr 26.


TIPIC Syndrome: Beyond the Myth of Carotidynia, a New Distinct Unclassified Entity.

Lecler A, Obadia M, Savatovsky J, Picard H, Charbonneau F, Menjot de Champfleur N, Naggara O, Carsin B, Amor-Sahli M, Cottier JP, Bensoussan J, Auffray-Calvier E, Varoquaux A, De Gaalon S, Calazel C, Nasr N, Volle G, Jianu DC, Gout O, Bonneville F, Sadik JC.

AJNR Am J Neuroradiol. 2017 Jul;38(7):1391-1398. doi: 10.3174/ajnr.A5214. Epub 2017 May 11.


Etiologies of acute demyelinating optic neuritis: an observational study of 110 patients.

Deschamps R, Lecler A, Lamirel C, Aboab J, Gueguen A, Bensa C, Vignal C, Gout O.

Eur J Neurol. 2017 Jun;24(6):875-879. doi: 10.1111/ene.13315. Epub 2017 May 6.


Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).

Baratella M, Forlani G, Raval GU, Tedeschi A, Gout O, Gessain A, Tosi G, Accolla RS.

PLoS Negl Trop Dis. 2017 Jan 17;11(1):e0005285. doi: 10.1371/journal.pntd.0005285. eCollection 2017 Jan.


Combined brain and anterior visual pathways' MRIs assist in early identification of neuromyelitis optica spectrum disorder at onset of optic neuritis.

Buch D, Savatovsky J, Gout O, Vignal C, Deschamps R.

Acta Neurol Belg. 2017 Mar;117(1):67-74. doi: 10.1007/s13760-016-0714-2. Epub 2016 Nov 1.


Favorable outcome of a pregnancy after fampridine exposition during the first month.

Maillart E, Gout O, Lubetzki C, Carpentier B, Nizard J.

J Neurol Sci. 2016 Nov 15;370:158. doi: 10.1016/j.jns.2016.09.033. Epub 2016 Sep 24. No abstract available.


MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.

Tourbah A, Lebrun-Frenay C, Edan G, Clanet M, Papeix C, Vukusic S, De Sèze J, Debouverie M, Gout O, Clavelou P, Defer G, Laplaud DA, Moreau T, Labauge P, Brochet B, Sedel F, Pelletier J; MS-SPI study group.

Mult Scler. 2016 Nov;22(13):1719-1731. Epub 2016 Sep 1.


Could quantitative longitudinal peak systolic strain help in the detection of left ventricular wall motion abnormalities in our daily echocardiographic practice?

Benyounes N, Lang S, Gout O, Ancédy Y, Etienney A, Cohen A.

Arch Cardiovasc Dis. 2016 Oct;109(10):533-541. doi: 10.1016/j.acvd.2016.02.007. Epub 2016 Jun 22.


Human T-Lymphotropic Virus Type 1-Induced Overexpression of Activated Leukocyte Cell Adhesion Molecule (ALCAM) Facilitates Trafficking of Infected Lymphocytes through the Blood-Brain Barrier.

Curis C, Percher F, Jeannin P, Montange T, Chevalier SA, Seilhean D, Cartier L, Couraud PO, Gout O, Gessain A, Ceccaldi PE, Afonso PV.

J Virol. 2016 Jul 27;90(16):7303-7312. doi: 10.1128/JVI.00539-16. Print 2016 Aug 15.


Plasma exchange response in 34 patients with severe optic neuritis.

Deschamps R, Gueguen A, Parquet N, Saheb S, Driss F, Mesnil M, Vignal C, Aboab J, Depaz R, Gout O.

J Neurol. 2016 May;263(5):883-887. doi: 10.1007/s00415-016-8073-8. Epub 2016 Mar 10. Erratum in: J Neurol. 2017 Jun 8;:.


Comparative efficacy of fingolimod vs natalizumab: A French multicenter observational study.

Barbin L, Rousseau C, Jousset N, Casey R, Debouverie M, Vukusic S, De Sèze J, Brassat D, Wiertlewski S, Brochet B, Pelletier J, Vermersch P, Edan G, Lebrun-Frenay C, Clavelou P, Thouvenot E, Camdessanché JP, Tourbah A, Stankoff B, Al Khedr A, Cabre P, Papeix C, Berger E, Heinzlef O, Debroucker T, Moreau T, Gout O, Bourre B, Créange A, Labauge P, Magy L, Defer G, Foucher Y, Laplaud DA; CFSEP and OFSEP groups.

Neurology. 2016 Feb 23;86(8):771-8. doi: 10.1212/WNL.0000000000002395. Epub 2016 Jan 29.


[New treatments and strategy in multiple sclerosis]

Guéguen A, Gout O.

Rev Prat. 2016 Jan;66(1):44-50. French.


Vaccinations and multiple sclerosis: what risks?

Gout O.

Rev Prat. 2015 Nov;65(9):1127-1129. French. No abstract available.


Hemisphere-dependent ipsilesional deficits in hemianopia: Sightblindness in the 'intact' visual field.

Cavézian C, Perez C, Peyrin C, Gaudry I, Obadia M, Gout O, Chokron S.

Cortex. 2015 Aug;69:166-74. doi: 10.1016/j.cortex.2015.05.010. Epub 2015 May 18.


High doses of biotin in chronic progressive multiple sclerosis: a pilot study.

Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, Gout O, Lyon-Caen O, Tourbah A.

Mult Scler Relat Disord. 2015 Mar;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. Epub 2015 Jan 24.


Criteria improving multiple sclerosis diagnosis at the first MRI.

Caucheteux N, Maarouf A, Genevray M, Leray E, Deschamps R, Chaunu MP, Daelman L, Ferré JC, Gout O, Pelletier J, Pierot L, Edan G, Tourbah A.

J Neurol. 2015;262(4):979-87. doi: 10.1007/s00415-015-7668-9. Epub 2015 Feb 17.


Spinal cord tumour misdiagnosed as seropositive neuromyelitis optica spectrum disorder.

Buch D, Dehais C, Savatovsky J, Mokhtari K, Gout O, Marignier R, Deschamps R.

Pract Neurol. 2015 Jun;15(3):228-9. doi: 10.1136/practneurol-2014-001010. Epub 2015 Jan 20. No abstract available.


Spontaneous regression of neuro-ophthalmological sarcoidosis.

Ougier N, Roux P, Lamirel C, Tournaire-Marques E, Tandjaoui-Lambiotte Y, Gout O, Deschamps R.

Clin Neurol Neurosurg. 2015 Mar;130:6-7. doi: 10.1016/j.clineuro.2014.11.025. Epub 2014 Dec 19. No abstract available.


Can global longitudinal strain predict reduced left ventricular ejection fraction in daily echocardiographic practice?

Benyounes N, Lang S, Soulat-Dufour L, Obadia M, Gout O, Chevalier G, Cohen A.

Arch Cardiovasc Dis. 2015 Jan;108(1):50-6. doi: 10.1016/j.acvd.2014.08.003. Epub 2014 Dec 17.


HTLV-1 bZIP factor HBZ promotes cell proliferation and genetic instability by activating OncomiRs.

Vernin C, Thenoz M, Pinatel C, Gessain A, Gout O, Delfau-Larue MH, Nazaret N, Legras-Lachuer C, Wattel E, Mortreux F.

Cancer Res. 2014 Nov 1;74(21):6082-93. doi: 10.1158/0008-5472.CAN-13-3564. Epub 2014 Sep 9.


Forcing open doors using images: ruptured aortic arch atheroma visualized by TEE in a stroke patient.

Benyounes N, Welschbillig S, Gout O, Williams M, Chevalier G, Obadia M.

Int J Stroke. 2014 Aug;9(6):E29-30. doi: 10.1111/ijs.12310. No abstract available.


Northern African strains of human T-lymphotropic virus type 1 arose from a recombination event.

Desrames A, Cassar O, Gout O, Hermine O, Taylor GP, Afonso PV, Gessain A.

J Virol. 2014 Sep 1;88(17):9782-8. doi: 10.1128/JVI.01591-14. Epub 2014 Jun 18.


Abnormal inflammatory activity returns after natalizumab cessation in multiple sclerosis.

Gueguen A, Roux P, Deschamps R, Moulignier A, Bensa C, Savatovsky J, Heran F, Gout O.

J Neurol Neurosurg Psychiatry. 2014 Sep;85(9):1038-40. doi: 10.1136/jnnp-2014-307591. Epub 2014 May 29.


Optic neuritis revealing Kikuchi-Fujimoto disease.

Bouquet F, Maillart E, Vignal C, Battistella M, Meignin V, Galicier L, Gout O.

Mult Scler. 2014 Jul;20(8):1140-2. doi: 10.1177/1352458514525000. Epub 2014 Mar 4.


Treatment effect on brain atrophy correlates with treatment effect on disability in multiple sclerosis.

Gout O, Tourbah A.

Ann Neurol. 2014 Mar;75(3):463. doi: 10.1002/ana.24112. Epub 2014 Feb 24. No abstract available.


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