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Items: 1 to 50 of 188

1.

The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.

Fulcher LJ, Bozatzi P, Tachie-Menson T, Wu KZL, Cummins TD, Bufton JC, Pinkas DM, Dunbar K, Shrestha S, Wood NT, Weidlich S, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Dingwell KS, Smith JC, Bullock AN, Sapkota GP.

Sci Signal. 2018 May 22;11(531). pii: eaao2341. doi: 10.1126/scisignal.aao2341.

PMID:
29789297
2.

PAWS1 controls Wnt signalling through association with casein kinase 1α.

Bozatzi P, Dingwell KS, Wu KZ, Cooper F, Cummins TD, Hutchinson LD, Vogt J, Wood NT, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Smith JC, Sapkota GP.

EMBO Rep. 2018 Apr;19(4). pii: e44807. doi: 10.15252/embr.201744807. Epub 2018 Mar 7.

3.

Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report.

McGuire HM, Shklovskaya E, Edwards J, Trevillian PR, McCaughan GW, Bertolino P, McKenzie C, Gourlay R, Gallagher SJ, Fazekas de St Groth B, Hersey P.

Cancer Immunol Immunother. 2018 Apr;67(4):563-573. doi: 10.1007/s00262-017-2107-7. Epub 2017 Dec 30.

4.

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3).

Logie L, Van Aalten L, Knebel A, Force T, Hastie CJ, MacLauchlan H, Campbell DG, Gourlay R, Prescott A, Davidson J, Fuller W, Sutherland C.

Sci Rep. 2017 Dec 15;7(1):17682. doi: 10.1038/s41598-017-17087-6.

5.

PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.

Cummins TD, Wu KZL, Bozatzi P, Dingwell KS, Macartney TJ, Wood NT, Varghese J, Gourlay R, Campbell DG, Prescott A, Griffis E, Smith JC, Sapkota GP.

J Cell Sci. 2018 Jan 10;131(1). pii: jcs202390. doi: 10.1242/jcs.202390.

6.

A mutant O-GlcNAcase enriches Drosophila developmental regulators.

Selvan N, Williamson R, Mariappa D, Campbell DG, Gourlay R, Ferenbach AT, Aristotelous T, Hopkins-Navratilova I, Trost M, van Aalten DMF.

Nat Chem Biol. 2017 Aug;13(8):882-887. doi: 10.1038/nchembio.2404. Epub 2017 Jun 12.

PMID:
28604694
7.

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.

Lai YC, Kondapalli C, Lehneck R, Procter JB, Dill BD, Woodroof HI, Gourlay R, Peggie M, Macartney TJ, Corti O, Corvol JC, Campbell DG, Itzen A, Trost M, Muqit MM.

EMBO J. 2015 Nov 12;34(22):2840-61. doi: 10.15252/embj.201591593. Epub 2015 Oct 15.

8.

Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization.

Herhaus L, Perez-Oliva AB, Cozza G, Gourlay R, Weidlich S, Campbell DG, Pinna LA, Sapkota GP.

Sci Signal. 2015 Apr 14;8(372):ra35. doi: 10.1126/scisignal.aaa0441.

9.

Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1.

Zhang N, Gordon SL, Fritsch MJ, Esoof N, Campbell DG, Gourlay R, Velupillai S, Macartney T, Peggie M, van Aalten DM, Cousin MA, Alessi DR.

J Neurosci. 2015 Feb 11;35(6):2492-507. doi: 10.1523/JNEUROSCI.4248-14.2015.

10.

Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC.

Tape CJ, Worboys JD, Sinclair J, Gourlay R, Vogt J, McMahon KM, Trost M, Lauffenburger DA, Lamont DJ, Jørgensen C.

Anal Chem. 2014 Oct 21;86(20):10296-302. doi: 10.1021/ac5025842. Epub 2014 Oct 2.

11.

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

Patel K, Foretz M, Marion A, Campbell DG, Gourlay R, Boudaba N, Tournier E, Titchenell P, Peggie M, Deak M, Wan M, Kaestner KH, Göransson O, Viollet B, Gray NS, Birnbaum MJ, Sutherland C, Sakamoto K.

Nat Commun. 2014 Aug 4;5:4535. doi: 10.1038/ncomms5535.

12.

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.

Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, Hofmann K, Alessi DR, Knebel A, Trost M, Muqit MM.

Biochem J. 2014 May 15;460(1):127-39. doi: 10.1042/BJ20140334.

13.

Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction.

van der Wijst J, Blanchard MG, Woodroof HI, Macartney TJ, Gourlay R, Hoenderop JG, Bindels RJ, Alessi DR.

Biochem J. 2014 Jun 1;460(2):165-75. doi: 10.1042/BJ20131639.

14.

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling.

Vogt J, Dingwell KS, Herhaus L, Gourlay R, Macartney T, Campbell D, Smith JC, Sapkota GP.

Open Biol. 2014 Feb 19;4:130210. doi: 10.1098/rsob.130210.

15.

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

de Los Heros P, Alessi DR, Gourlay R, Campbell DG, Deak M, Macartney TJ, Kahle KT, Zhang J.

Biochem J. 2014 Mar 15;458(3):559-73. doi: 10.1042/BJ20131478.

16.

Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity.

Houde VP, Ritorto MS, Gourlay R, Varghese J, Davies P, Shpiro N, Sakamoto K, Alessi DR.

Biochem J. 2014 Feb 15;458(1):41-56. doi: 10.1042/BJ20131324.

17.

Long-term follow-up of ACL reconstruction with hamstring autograft.

Leiter JR, Gourlay R, McRae S, de Korompay N, MacDonald PB.

Knee Surg Sports Traumatol Arthrosc. 2014 May;22(5):1061-9. doi: 10.1007/s00167-013-2466-3. Epub 2013 Apr 18. Review.

PMID:
23595537
18.

Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21.

De Wever V, Lloyd DC, Nasa I, Nimick M, Trinkle-Mulcahy L, Gourlay R, Morrice N, Moorhead GB.

PLoS One. 2012;7(6):e39510. doi: 10.1371/journal.pone.0039510. Epub 2012 Jun 28.

19.

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.

Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, Muqit MM.

Open Biol. 2012 May;2(5):120080. doi: 10.1098/rsob.120080.

20.

Arabidopsis thaliana histone deacetylase 14 (HDA14) is an α-tubulin deacetylase that associates with PP2A and enriches in the microtubule fraction with the putative histone acetyltransferase ELP3.

Tran HT, Nimick M, Uhrig RG, Templeton G, Morrice N, Gourlay R, DeLong A, Moorhead GB.

Plant J. 2012 Jul;71(2):263-72. doi: 10.1111/j.1365-313X.2012.04984.x. Epub 2012 May 2.

21.

Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β.

Gleason CE, Ordureau A, Gourlay R, Arthur JS, Cohen P.

J Biol Chem. 2011 Oct 14;286(41):35663-74. doi: 10.1074/jbc.M111.267567. Epub 2011 Aug 23.

22.

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases.

Filippi BM, de los Heros P, Mehellou Y, Navratilova I, Gourlay R, Deak M, Plater L, Toth R, Zeqiraj E, Alessi DR.

EMBO J. 2011 May 4;30(9):1730-41. doi: 10.1038/emboj.2011.78. Epub 2011 Mar 18.

23.

A screen for novel phosphoinositide 3-kinase effector proteins.

Dixon MJ, Gray A, Boisvert FM, Agacan M, Morrice NA, Gourlay R, Leslie NR, Downes CP, Batty IH.

Mol Cell Proteomics. 2011 Apr;10(4):M110.003178. doi: 10.1074/mcp.M110.003178. Epub 2011 Jan 24.

24.

The role of TBK1 and IKKε in the expression and activation of Pellino 1.

Smith H, Liu XY, Dai L, Goh ET, Chan AT, Xi J, Seh CC, Qureshi IA, Lescar J, Ruedl C, Gourlay R, Morton S, Hough J, McIver EG, Cohen P, Cheung PC.

Biochem J. 2011 Mar 15;434(3):537-48. doi: 10.1042/BJ20101421.

25.

Displacement affinity chromatography of protein phosphatase one (PP1) complexes.

Moorhead GB, Trinkle-Mulcahy L, Nimick M, De Wever V, Campbell DG, Gourlay R, Lam YW, Lamond AI.

BMC Biochem. 2008 Nov 10;9:28. doi: 10.1186/1471-2091-9-28.

26.

Novel procedure to investigate the effect of phosphorylation on protein complex formation in vitro and in cells.

Rembutsu M, Soutar MP, Van Aalten L, Gourlay R, Hastie CJ, McLauchlan H, Morrice NA, Cole AR, Sutherland C.

Biochemistry. 2008 Feb 19;47(7):2153-61. doi: 10.1021/bi702030w. Epub 2008 Jan 26.

PMID:
18220421
27.

Identification of Protor as a novel Rictor-binding component of mTOR complex-2.

Pearce LR, Huang X, Boudeau J, Pawłowski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR.

Biochem J. 2007 Aug 1;405(3):513-22.

28.

Four dimensions.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2005;18(4-5):331-2. No abstract available.

PMID:
16167647
29.

Quality assurance.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2005;18(2-3):168-9. No abstract available.

PMID:
15974512
30.

Patient safety.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2005;18(1):5-6. No abstract available.

PMID:
15819119
31.

Quality and more quality.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2004;17(7):366-7. No abstract available.

PMID:
15552391
32.

Rare complication of colonoscopy.

Al Alawi I, Gourlay R.

ANZ J Surg. 2004 Jul;74(7):605-6. No abstract available.

PMID:
15230804
33.

Staffing .

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2004;17(1):7-8. No abstract available.

PMID:
15046465
34.

Spontaneous improvement in late rectal mucosal changes after radiotherapy for prostate cancer.

O'Brien PC, Hamilton CS, Denham JW, Gourlay R, Franklin CI.

Int J Radiat Oncol Biol Phys. 2004 Jan 1;58(1):75-80.

PMID:
14697423
35.

Quality communication.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2003;16(2-3):114-5. No abstract available.

PMID:
12870250
36.

Seminars on management topics for doctors in training.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2001;14(6-7):280-1. No abstract available.

PMID:
11776234
37.

The customer chain.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2000;13(4-5):198-9. No abstract available.

PMID:
11486673
38.

Quality and the appraisal process.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2000;13(6-7):288-9. No abstract available.

PMID:
11484646
39.

The interface.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2001;14(2-3):102-3. No abstract available.

PMID:
11436744
40.

Objectives of a quality assurance programme.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 2000;13(1):7. No abstract available.

PMID:
11183227
41.

Managerial governance to parallel clinical governance.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1999;12(6-7):278. No abstract available.

PMID:
10724570
42.

Clinical governance.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1999;12(1):5. No abstract available.

PMID:
10351022
43.

Quality at the core.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1998;11(6-7):214. No abstract available.

PMID:
10339094
44.

Clinical and managerial quality.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1998;11(6-7):180. No abstract available.

PMID:
10339089
45.

Re-engineering.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1998;11(2-3):76. No abstract available.

PMID:
10185319
46.

Quality in a service function. Value added?

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1998;11(2-3):40. No abstract available.

PMID:
10185313
47.

Quality assurance.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1997;10(6-7):253. No abstract available.

PMID:
10175769
48.

The pressure for quality.

Gourlay R.

Int J Health Care Qual Assur Inc Leadersh Health Serv. 1997;10(4-5):178. No abstract available.

PMID:
10173358
49.

Sigmoidoscopic neurosurgery? Treatment of an unusual complication of ventriculoperitoneal shunting.

Brown SR, Gourlay R, Battersby RD.

Br J Neurosurg. 1996 Aug;10(4):419-20.

PMID:
8864513
50.

Handling complaints successfully.

Gourlay R.

Int J Health Care Qual Assur. 1996;9(3):3. No abstract available.

PMID:
10158423

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