Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41


The potential of respiration inhibition as a new approach to combat human fungal pathogens.

Duvenage L, Munro CA, Gourlay CW.

Curr Genet. 2019 Dec;65(6):1347-1353. doi: 10.1007/s00294-019-01001-w. Epub 2019 Jun 6. Review.


Inhibition of Classical and Alternative Modes of Respiration in Candida albicans Leads to Cell Wall Remodeling and Increased Macrophage Recognition.

Duvenage L, Walker LA, Bojarczuk A, Johnston SA, MacCallum DM, Munro CA, Gourlay CW.

mBio. 2019 Jan 29;10(1). pii: e02535-18. doi: 10.1128/mBio.02535-18.


The Human Gut Colonizer Blastocystis Respires Using Complex II and Alternative Oxidase to Buffer Transient Oxygen Fluctuations in the Gut.

Tsaousis AD, Hamblin KA, Elliott CR, Young L, Rosell-Hidalgo A, Gourlay CW, Moore AL, van der Giezen M.

Front Cell Infect Microbiol. 2018 Oct 22;8:371. doi: 10.3389/fcimb.2018.00371. eCollection 2018.


Lipotoxicty in yeast: a focus on plasma membrane signalling and membrane contact sites.

Rockenfeller P, Gourlay CW.

FEMS Yeast Res. 2018 Jun 1;18(4). doi: 10.1093/femsyr/foy034. Review.


Ras signalling in pathogenic yeasts.

Pentland DR, Piper-Brown E, Mühlschlegel FA, Gourlay CW.

Microb Cell. 2017 Dec 18;5(2):63-73. doi: 10.15698/mic2018.02.612. Review.


Guidelines and recommendations on yeast cell death nomenclature.

Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F.

Microb Cell. 2018 Jan 1;5(1):4-31. doi: 10.15698/mic2018.01.607. Review.


Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity.

Rockenfeller P, Smolnig M, Diessl J, Bashir M, Schmiedhofer V, Knittelfelder O, Ring J, Franz J, Foessl I, Khan MJ, Rost R, Graier WF, Kroemer G, Zimmermann A, Carmona-Gutierrez D, Eisenberg T, Büttner S, Sigrist SJ, Kühnlein RP, Kohlwein SD, Gourlay CW, Madeo F.

Cell Death Differ. 2018 Mar;25(4):767-783. doi: 10.1038/s41418-017-0014-2. Epub 2017 Dec 11.


Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS.

Saintas E, Abrahams L, Ahmad GT, Ajakaiye AM, AlHumaidi AS, Ashmore-Harris C, Clark I, Dura UK, Fixmer CN, Ike-Morris C, Mato Prado M, Mccullough D, Mishra S, Schöler KM, Timur H, Williamson MD, Alatsatianos M, Bahsoun B, Blackburn E, Hogwood CE, Lithgow PE, Rowe M, Yiangou L, Rothweiler F, Cinatl J Jr, Zehner R, Baines AJ, Garrett MD, Gourlay CW, Griffin DK, Gullick WJ, Hargreaves E, Howard MJ, Lloyd DR, Rossman JS, Smales CM, Tsaousis AD, von der Haar T, Wass MN, Michaelis M.

PLoS One. 2017 Feb 13;12(2):e0172140. doi: 10.1371/journal.pone.0172140. eCollection 2017.


The control of translational accuracy is a determinant of healthy ageing in yeast.

von der Haar T, Leadsham JE, Sauvadet A, Tarrant D, Adam IS, Saromi K, Laun P, Rinnerthaler M, Breitenbach-Koller H, Breitenbach M, Tuite MF, Gourlay CW.

Open Biol. 2017 Jan;7(1). pii: 160291. doi: 10.1098/rsob.160291.


Inappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism.

Tarrant DJ, Stirpe M, Rowe M, Howard MJ, von der Haar T, Gourlay CW.

J Cell Sci. 2016 Dec 15;129(24):4455-4465. Epub 2016 Nov 2.


New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis.

Bastow EL, Peswani AR, Tarrant DS, Pentland DR, Chen X, Morgan A, Staniforth GL, Tullet JM, Rowe ML, Howard MJ, Tuite MF, Gourlay CW.

J Cell Sci. 2016 Nov 1;129(21):4118-4129. Epub 2016 Sep 21.


Candida biofilm formation on voice prostheses.

Talpaert MJ, Balfour A, Stevens S, Baker M, Muhlschlegel FA, Gourlay CW.

J Med Microbiol. 2015 Mar;64(Pt 3):199-208. doi: 10.1099/jmm.0.078717-0. Epub 2014 Aug 8. Review.


Cellular redox homeostasis, reactive oxygen species and replicative ageing in Saccharomyces cerevisiae.

Ayer A, Gourlay CW, Dawes IW.

FEMS Yeast Res. 2014 Feb;14(1):60-72. doi: 10.1111/1567-1364.12114. Epub 2013 Nov 8. Review.


Actin - a biosensor that determines cell fate in yeasts.

Smethurst DG, Dawes IW, Gourlay CW.

FEMS Yeast Res. 2014 Feb;14(1):89-95. doi: 10.1111/1567-1364.12119. Epub 2013 Nov 26. Review.


Loss of cytochrome c oxidase promotes RAS-dependent ROS production from the ER resident NADPH oxidase, Yno1p, in yeast.

Leadsham JE, Sanders G, Giannaki S, Bastow EL, Hutton R, Naeimi WR, Breitenbach M, Gourlay CW.

Cell Metab. 2013 Aug 6;18(2):279-86. doi: 10.1016/j.cmet.2013.07.005.


Yeast between life and death: a summary of the Ninth International Meeting on Yeast Apoptosis in Rome, Italy, 17-20 September 2012.

Guaragnella N, Palermo V, Burhans WC, Gourlay CW, Ludovico P, Madeo F, Giannattasio S, Mazzoni C.

Cell Death Differ. 2013 Sep;20(9):1281-3. doi: 10.1038/cdd.2013.71. Epub 2013 Jun 28. No abstract available.


Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast.

Rinnerthaler M, Büttner S, Laun P, Heeren G, Felder TK, Klinger H, Weinberger M, Stolze K, Grousl T, Hasek J, Benada O, Frydlova I, Klocker A, Simon-Nobbe B, Jansko B, Breitenbach-Koller H, Eisenberg T, Gourlay CW, Madeo F, Burhans WC, Breitenbach M.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8658-63. doi: 10.1073/pnas.1201629109. Epub 2012 May 14.


Identification of new surfaces of cofilin that link mitochondrial function to the control of multi-drug resistance.

Kotiadis VN, Leadsham JE, Bastow EL, Gheeraert A, Whybrew JM, Bard M, Lappalainen P, Gourlay CW.

J Cell Sci. 2012 May 1;125(Pt 9):2288-99. doi: 10.1242/jcs.099390. Epub 2012 Feb 17.


H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphatase Ptc4.

Di Y, Holmes EJ, Butt A, Dawson K, Mironov A, Kotiadis VN, Gourlay CW, Jones N, Wilkinson CR.

EMBO J. 2012 Feb 1;31(3):563-75. doi: 10.1038/emboj.2011.438. Epub 2011 Dec 2.


Cellular ageing and the actin cytoskeleton.

Amberg D, Leadsham JE, Kotiadis V, Gourlay CW.

Subcell Biochem. 2012;57:331-52. doi: 10.1007/978-94-007-2561-4_15. Review.


Using yeast models to probe the molecular basis of amyotrophic lateral sclerosis.

Bastow EL, Gourlay CW, Tuite MF.

Biochem Soc Trans. 2011 Oct;39(5):1482-7. doi: 10.1042/BST0391482. Review.


A new Canterbury tale: the eighth International Meeting on Yeast Apoptosis in Canterbury, UK, 2-6 May 2011.

Carmona-Gutierrez D, Ruckenstuhl C, Bauer MA, Netzberger C, Eisenberg T, Braun RJ, Rockenfeller P, Khoury CM, Moitzi B, Sommer C, Ring J, Schroeder S, Habernig L, Mazzoni C, Winderickx J, Gourlay CW, Madeo F.

Cell Death Differ. 2011 Dec;18(12):1948-9. doi: 10.1038/cdd.2011.115. Epub 2011 Sep 2. No abstract available.


Transcriptomic and phenotypic analysis of the effects of T-2 toxin on Saccharomyces cerevisiae: evidence of mitochondrial involvement.

Jossé L, Li X, Coker RD, Gourlay CW, Evans IH.

FEMS Yeast Res. 2011 Feb;11(1):133-50. doi: 10.1111/j.1567-1364.2010.00699.x. Epub 2010 Nov 29.


cAMP/PKA signaling balances respiratory activity with mitochondria dependent apoptosis via transcriptional regulation.

Leadsham JE, Gourlay CW.

BMC Cell Biol. 2010 Nov 25;11:92. doi: 10.1186/1471-2121-11-92.


Apoptosis and the yeast actin cytoskeleton.

Leadsham JE, Kotiadis VN, Tarrant DJ, Gourlay CW.

Cell Death Differ. 2010 May;17(5):754-62. doi: 10.1038/cdd.2009.196. Epub 2009 Dec 18. Review.


Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.

Sudarshan S, Sourbier C, Kong HS, Block K, Valera Romero VA, Yang Y, Galindo C, Mollapour M, Scroggins B, Goode N, Lee MJ, Gourlay CW, Trepel J, Linehan WM, Neckers L.

Mol Cell Biol. 2009 Aug;29(15):4080-90. doi: 10.1128/MCB.00483-09. Epub 2009 May 26.


Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast.

Leadsham JE, Miller K, Ayscough KR, Colombo S, Martegani E, Sudbery P, Gourlay CW.

J Cell Sci. 2009 Mar 1;122(Pt 5):706-15. doi: 10.1242/jcs.042424. Epub 2009 Feb 10.


A role for actin in regulating apoptosis/programmed cell death: evidence spanning yeast, plants and animals.

Franklin-Tong VE, Gourlay CW.

Biochem J. 2008 Aug 1;413(3):389-404. doi: 10.1042/BJ20080320. Review.


Cytoskeletal induced apoptosis in yeast.

Leadsham JE, Gourlay CW.

Biochim Biophys Acta. 2008 Jul;1783(7):1406-12. doi: 10.1016/j.bbamcr.2008.01.019. Epub 2008 Feb 8. Review.


Apoptosis in yeast--mechanisms and benefits to a unicellular organism.

Gourlay CW, Du W, Ayscough KR.

Mol Microbiol. 2006 Dec;62(6):1515-21. Review.


A role for actin in aging and apoptosis.

Gourlay CW, Ayscough KR.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1260-4. Review.


The actin cytoskeleton in ageing and apoptosis.

Gourlay CW, Ayscough KR.

FEMS Yeast Res. 2005 Dec;5(12):1193-8. Epub 2005 Aug 29. Review.


The actin cytoskeleton: a key regulator of apoptosis and ageing?

Gourlay CW, Ayscough KR.

Nat Rev Mol Cell Biol. 2005 Jul;6(7):583-9. Review.


Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast.

Gourlay CW, Ayscough KR.

J Cell Sci. 2005 May 15;118(Pt 10):2119-32. Epub 2005 Apr 26.


A role for the actin cytoskeleton in cell death and aging in yeast.

Gourlay CW, Carpp LN, Timpson P, Winder SJ, Ayscough KR.

J Cell Biol. 2004 Mar 15;164(6):803-9.


An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast.

Gourlay CW, Dewar H, Warren DT, Costa R, Satish N, Ayscough KR.

J Cell Sci. 2003 Jun 15;116(Pt 12):2551-64. Epub 2003 May 6.


Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics.

Warren DT, Andrews PD, Gourlay CW, Ayscough KR.

J Cell Sci. 2002 Apr 15;115(Pt 8):1703-15.


Analytical performance of the Genzyme LipoPro Lp(a) kit for plasma lipoprotein(a)-cholesterol assay.

Gaw A, Brown EA, Gourlay CW, Bell MA.

Br J Biomed Sci. 2000;57(1):13-8.


Evaluation of a new automated latex agglutination assay for lipoprotein(a): comparison with a manual ELISA.

Gaw A, Gourlay CW, Brown EA, Bell MA.

Clin Chim Acta. 1997 May 28;261(2):175-83. No abstract available.


Supplemental Content

Loading ...
Support Center