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Items: 7


LJ000328, a novel ALK2/3 kinase inhibitor, represses hepcidin and significantly improves the phenotype of IRIDA.

Belot A, Gourbeyre O, Fay A, Palin A, Besson C, Latour C, Hopkins CR, Tidmarsh GF, Coppin H, Roth MP, Ritter MR, Hong CC, Meynard D.

Haematologica. 2019 Dec 5. pii: haematol.2019.236133. doi: 10.3324/haematol.2019.236133. [Epub ahead of print]


Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge.

Latour C, Besson-Fournier C, Gourbeyre O, Meynard D, Roth MP, Coppin H.

Blood. 2017 Nov 23;130(21):2339-2343. doi: 10.1182/blood-2017-07-795658. Epub 2017 Oct 11.


Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B.

Besson-Fournier C, Gineste A, Latour C, Gourbeyre O, Meynard D, Martin P, Oswald E, Coppin H, Roth MP.

Blood. 2017 Jan 26;129(4):533-536. doi: 10.1182/blood-2016-10-748541. Epub 2016 Nov 30. No abstract available.


Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.

Nai A, Rubio A, Campanella A, Gourbeyre O, Artuso I, Bordini J, Gineste A, Latour C, Besson-Fournier C, Lin HY, Coppin H, Roth MP, Camaschella C, Silvestri L, Meynard D.

Blood. 2016 May 12;127(19):2327-36. doi: 10.1182/blood-2015-11-681494. Epub 2016 Jan 11.


Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.

Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.

Hepatology. 2016 Jan;63(1):126-37. doi: 10.1002/hep.28254. Epub 2015 Nov 12.


Proteomics of muscle chronological ageing in post-menopausal women.

Gueugneau M, Coudy-Gandilhon C, Gourbeyre O, Chambon C, Combaret L, Polge C, Taillandier D, Attaix D, Friguet B, Maier AB, Butler-Browne G, B├ęchet D.

BMC Genomics. 2014 Dec 23;15:1165. doi: 10.1186/1471-2164-15-1165.


Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids.

Averous J, Lambert-Langlais S, Carraro V, Gourbeyre O, Parry L, B'Chir W, Muranishi Y, Jousse C, Bruhat A, Maurin AC, Proud CG, Fafournoux P.

Cell Signal. 2014 Sep;26(9):1918-27. doi: 10.1016/j.cellsig.2014.04.019. Epub 2014 May 2.


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