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Items: 1 to 50 of 202

1.

Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models.

Homer-Bouthiette C, Zhao Y, Shunkwiler LB, Van Peel B, Garrett-Mayer E, Baird RC, Rissman AI, Guest ST, Ethier SP, John MC, Powers PA, Haag JD, Gould MN, Smits BMG.

BMC Cancer. 2018 Dec 10;18(1):1233. doi: 10.1186/s12885-018-5109-8.

2.

Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells.

Zumwalde NA, Haag JD, Gould MN, Gumperz JE.

Breast Cancer Res. 2018 Sep 12;20(1):111. doi: 10.1186/s13058-018-1036-5.

3.

The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation.

Henning AN, Haag JD, Smits BM, Gould MN.

PLoS Genet. 2016 Aug 18;12(8):e1006261. doi: 10.1371/journal.pgen.1006261. eCollection 2016 Aug.

4.

Analysis of Immune Cells from Human Mammary Ductal Epithelial Organoids Reveals Vδ2+ T Cells That Efficiently Target Breast Carcinoma Cells in the Presence of Bisphosphonate.

Zumwalde NA, Haag JD, Sharma D, Mirrielees JA, Wilke LG, Gould MN, Gumperz JE.

Cancer Prev Res (Phila). 2016 Apr;9(4):305-16. doi: 10.1158/1940-6207.CAPR-15-0370-T. Epub 2016 Jan 25.

5.

The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation.

Smits BM, Haag JD, Rissman AI, Sharma D, Tran A, Schoenborn AA, Baird RC, Peiffer DS, Leinweber DQ, Muelbl MJ, Meilahn AL, Eichelberg MR, Leng N, Kendziorski C, John MC, Powers PA, Alexander CM, Gould MN.

PLoS Genet. 2013 Jun;9(6):e1003549. doi: 10.1371/journal.pgen.1003549. Epub 2013 Jun 13.

6.

EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments.

Leng N, Dawson JA, Thomson JA, Ruotti V, Rissman AI, Smits BM, Haag JD, Gould MN, Stewart RM, Kendziorski C.

Bioinformatics. 2013 Apr 15;29(8):1035-43. doi: 10.1093/bioinformatics/btt087. Epub 2013 Feb 21. Erratum in: Bioinformatics. 2013 Aug 15;29(16):2073.

7.

The long path from QTL to gene.

Drinkwater NR, Gould MN.

PLoS Genet. 2012 Sep;8(9):e1002975. doi: 10.1371/journal.pgen.1002975. Epub 2012 Sep 20. No abstract available.

8.

Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer.

Pirone JR, D'Arcy M, Stewart DA, Hines WC, Johnson M, Gould MN, Yaswen P, Jerry DJ, Smith Schneider S, Troester MA.

Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1735-44. doi: 10.1158/1055-9965.EPI-12-0451. Epub 2012 Aug 2.

9.

Effective flow cytometric phenotyping of cells using minimal amounts of antibody.

Sharma D, Eichelberg MR, Haag JD, Meilahn AL, Muelbl MJ, Schell K, Smits BM, Gould MN.

Biotechniques. 2012 Jul;53(1):57-60. doi: 10.2144/0000113854.

10.

Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats.

Sharma D, Smits BM, Eichelberg MR, Meilahn AL, Muelbl MJ, Haag JD, Gould MN.

PLoS One. 2011;6(10):e26145. doi: 10.1371/journal.pone.0026145. Epub 2011 Oct 12.

11.

The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions.

Smits BM, Sharma D, Samuelson DJ, Woditschka S, Mau B, Haag JD, Gould MN.

Breast Cancer Res. 2011 Aug 16;13(4):R81. doi: 10.1186/bcr2933.

12.

Mcs5c: a mammary carcinoma susceptibility locus located in a gene desert that associates with tenascin C expression.

Veillet AL, Haag JD, Remfert JL, Meilahn AL, Samuelson DJ, Gould MN.

Cancer Prev Res (Phila). 2011 Jan;4(1):97-106. doi: 10.1158/1940-6207.CAPR-10-0187.

13.

ENU mutagenesis to generate genetically modified rat models.

van Boxtel R, Gould MN, Cuppen E, Smits BM.

Methods Mol Biol. 2010;597:151-67. doi: 10.1007/978-1-60327-389-3_11.

PMID:
20013232
14.

The utility of comparative genetics to inform breast cancer prevention strategies.

Gould MN.

Genetics. 2009 Oct;183(2):409-12. doi: 10.1534/genetics.109.108480.

15.

"Gene targeting in the rat? Cut it out!".

Smits BM, Gould MN.

Mol Interv. 2009 Oct;9(5):226-9. doi: 10.1124/mi.9.5.5. No abstract available.

PMID:
19828829
16.

A short-term rat mammary carcinogenesis model for the prevention of hormonally responsive and nonresponsive in situ carcinomas.

Woditschka S, Haag JD, Sullivan R, Gould MN.

Cancer Prev Res (Phila). 2009 Feb;2(2):153-60. doi: 10.1158/1940-6207.CAPR-08-0114.

17.

Freund's vaccine adjuvant promotes Her2/neu breast cancer.

Cotroneo MS, Haag JD, Stapel NR, Waller JL, Woditschka S, Gould MN.

BMC Cancer. 2009 Jan 14;9:19. doi: 10.1186/1471-2407-9-19.

18.

Chemopreventive effects of celecoxib are limited to hormonally responsive mammary carcinomas in the neu-induced retroviral rat model.

Woditschka S, Haag JD, Mau B, Lubet RA, Gould MN.

Breast Cancer Res. 2008;10(1):R18. doi: 10.1186/bcr1864. Epub 2008 Feb 15.

19.

Genetically engineered rat models for breast cancer.

Smits BM, Cotroneo MS, Haag JD, Gould MN.

Breast Dis. 2007;28:53-61. Review.

PMID:
18057543
20.

Neutrophil gelatinase-associated lipocalin (NGAL) is a predictor of poor prognosis in human primary breast cancer.

Bauer M, Eickhoff JC, Gould MN, Mundhenke C, Maass N, Friedl A.

Breast Cancer Res Treat. 2008 Apr;108(3):389-97. Epub 2007 Jun 7.

PMID:
17554627
21.

Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk.

Samuelson DJ, Hesselson SE, Aperavich BA, Zan Y, Haag JD, Trentham-Dietz A, Hampton JM, Mau B, Chen KS, Baynes C, Khaw KT, Luben R, Perkins B, Shah M, Pharoah PD, Dunning AM, Easton DF, Ponder BA, Gould MN.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6299-304. Epub 2007 Apr 2.

22.

A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer.

Amos-Landgraf JM, Kwong LN, Kendziorski CM, Reichelderfer M, Torrealba J, Weichert J, Haag JD, Chen KS, Waller JL, Gould MN, Dove WF.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4036-41. Epub 2007 Feb 27.

23.

Estrogen receptor-positive mammary tumorigenesis in TGFalpha transgenic mice progresses with progesterone receptor loss.

Rose-Hellekant TA, Schroeder MD, Brockman JL, Zhdankin O, Bolstad R, Chen KS, Gould MN, Schuler LA, Sandgren EP.

Oncogene. 2007 Aug 9;26(36):5238-46. Epub 2007 Mar 5.

24.

Characterizing a rat Brca2 knockout model.

Cotroneo MS, Haag JD, Zan Y, Lopez CC, Thuwajit P, Petukhova GV, Camerini-Otero RD, Gendron-Fitzpatrick A, Griep AE, Murphy CJ, Dubielzig RR, Gould MN.

Oncogene. 2007 Mar 8;26(11):1626-35. Epub 2006 Sep 11.

PMID:
16964288
25.

Neu-induced retroviral rat mammary carcinogenesis: a novel chemoprevention model for both hormonally responsive and nonresponsive mammary carcinomas.

Woditschka S, Haag JD, Waller JL, Monson DM, Hitt AA, Brose HL, Hu R, Zheng Y, Watson PA, Kim K, Lindstrom MJ, Mau B, Steele VE, Lubet RA, Gould MN.

Cancer Res. 2006 Jul 1;66(13):6884-91.

26.

The Mcs7 quantitative trait locus is associated with an increased susceptibility to mammary cancer in congenic rats and an allele-specific imbalance.

Cotroneo MS, Merry GM, Haag JD, Lan H, Shepel LA, Gould MN.

Oncogene. 2006 Aug 17;25(36):5011-7. Epub 2006 Mar 27.

PMID:
16568087
27.
28.

Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway.

Berchtold CM, Chen KS, Miyamoto S, Gould MN.

Cancer Res. 2005 Sep 15;65(18):8558-66.

29.
30.

A case-control study of the HER2 Ile655Val polymorphism in relation to risk of invasive breast cancer.

Nelson SE, Gould MN, Hampton JM, Trentham-Dietz A.

Breast Cancer Res. 2005;7(3):R357-64. Epub 2005 Mar 11.

32.

On the utility of pooling biological samples in microarray experiments.

Kendziorski C, Irizarry RA, Chen KS, Haag JD, Gould MN.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4252-7. Epub 2005 Mar 8.

33.
34.

On parametric empirical Bayes methods for comparing multiple groups using replicated gene expression profiles.

Kendziorski CM, Newton MA, Lan H, Gould MN.

Stat Med. 2003 Dec 30;22(24):3899-914.

PMID:
14673946
35.

Congenic rats reveal three independent Copenhagen alleles within the Mcs1 quantitative trait locus that confer resistance to mammary cancer.

Haag JD, Shepel LA, Kolman BD, Monson DM, Benton ME, Watts KT, Waller JL, Lopez-Guajardo CC, Samuelson DJ, Gould MN.

Cancer Res. 2003 Sep 15;63(18):5808-12.

36.

Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats.

Samuelson DJ, Haag JD, Lan H, Monson DM, Shultz MA, Kolman BD, Gould MN.

Carcinogenesis. 2003 Sep;24(9):1455-60. Epub 2003 Jul 4.

PMID:
12844486
37.
38.

Production of knockout rats using ENU mutagenesis and a yeast-based screening assay.

Zan Y, Haag JD, Chen KS, Shepel LA, Wigington D, Wang YR, Hu R, Lopez-Guajardo CC, Brose HL, Porter KI, Leonard RA, Hitt AA, Schommer SL, Elegbede AF, Gould MN.

Nat Biotechnol. 2003 Jun;21(6):645-51. Epub 2003 May 18.

PMID:
12754522
39.

Affinity with Raf is sufficient for Ras to efficiently induce rat mammary carcinomas.

McFarlin DR, Lindstrom MJ, Gould MN.

Carcinogenesis. 2003 Jan;24(1):99-105.

PMID:
12538354
40.

Androgen-dependent mammary carcinogenesis in rats transgenic for the Neu proto-oncogene.

Watson PA, Kim K, Chen KS, Gould MN.

Cancer Cell. 2002 Jul;2(1):67-79.

41.
42.

Regions of H- and K-ras that provide organ specificity/potency in mammary cancer induction.

Kim K, Lindstrom MJ, Gould MN.

Cancer Res. 2002 Mar 1;62(5):1241-5.

43.
44.

Evidence for unique calmodulin-dependent nuclear factor-kappaB regulation in WEHI-231 B cells.

Shumway SD, Berchtold CM, Gould MN, Miyamoto S.

Mol Pharmacol. 2002 Jan;61(1):177-85.

PMID:
11752219
45.

Genetic loci controlling breast cancer susceptibility in the Wistar-Kyoto rat.

Lan H, Kendziorski CM, Haag JD, Shepel LA, Newton MA, Gould MN.

Genetics. 2001 Jan;157(1):331-9.

46.

ras gene mutations are absent in NMU-induced mammary carcinomas from aging rats.

Thompson TA, Haag JD, Gould MN.

Carcinogenesis. 2000 Oct;21(10):1917-22.

PMID:
11023551
47.

Kinetics of mammary clonogenic cells and rat mammary cancer induction by X-rays or fission neutrons.

Kamiya K, Higgins PD, Tanner MA, Gould MN, Clifton KH.

J Radiat Res. 1999 Dec;40 Suppl:128-37.

48.

Radiobiological studies using synchrotron-produced ultrasoft X-rays.

Gould MN, Nelms BE, Hill CK, Mackay JF, Lindstrom MJ, Mackie TR, Deluca PM Jr.

J Radiat Res. 1999 Dec;40 Suppl:66-73.

49.

Genetic mapping of the rat Lcn2 gene to chromosome 3.

Chen K, Shepel LA, Stoesz SP, Brasic GM, Gould MN.

Cytogenet Cell Genet. 1999;87(3-4):273-4.

PMID:
10702692
50.

Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day.

Ripple GH, Gould MN, Arzoomanian RZ, Alberti D, Feierabend C, Simon K, Binger K, Tutsch KD, Pomplun M, Wahamaki A, Marnocha R, Wilding G, Bailey HH.

Clin Cancer Res. 2000 Feb;6(2):390-6.

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