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Items: 39

1.

Podoplanin neutralization improves cardiac remodeling and function after acute myocardial infarction.

Cimini M, Garikipati VNS, de Lucia C, Cheng Z, Wang C, Truongcao MM, Lucchese AM, Roy R, Benedict C, Goukassian DA, Koch WJ, Kishore R.

JCI Insight. 2019 Jul 9;5. pii: 126967. doi: 10.1172/jci.insight.126967.

2.

Short-Term Treatment with Esmolol Reverses Left Ventricular Hypertrophy in Adult Spontaneously Hypertensive Rats via Inhibition of Akt/NF-κB and NFATc4.

Quintana-Villamandos B, Goukassian DA, Sasi SP, Delgado-Baeza E.

Biomed Res Int. 2018 Feb 18;2018:2691014. doi: 10.1155/2018/2691014. eCollection 2018.

3.

Interleukin-10 Inhibits Bone Marrow Fibroblast Progenitor Cell-Mediated Cardiac Fibrosis in Pressure-Overloaded Myocardium.

Verma SK, Garikipati VNS, Krishnamurthy P, Schumacher SM, Grisanti LA, Cimini M, Cheng Z, Khan M, Yue Y, Benedict C, Truongcao MM, Rabinowitz JE, Goukassian DA, Tilley D, Koch WJ, Kishore R.

Circulation. 2017 Sep 5;136(10):940-953. doi: 10.1161/CIRCULATIONAHA.117.027889. Epub 2017 Jun 30.

4.

Different Sequences of Fractionated Low-Dose Proton and Single Iron-Radiation-Induced Divergent Biological Responses in the Heart.

Sasi SP, Yan X, Zuriaga-Herrero M, Gee H, Lee J, Mehrzad R, Song J, Onufrak J, Morgan J, Enderling H, Walsh K, Kishore R, Goukassian DA.

Radiat Res. 2017 Aug;188(2):191-203. doi: 10.1667/RR14667.1. Epub 2017 Jun 14.

5.

Interleukin-10 Deficiency Impairs Reparative Properties of Bone Marrow-Derived Endothelial Progenitor Cell Exosomes.

Yue Y, Garikipati VNS, Verma SK, Goukassian DA, Kishore R.

Tissue Eng Part A. 2017 Nov;23(21-22):1241-1250. doi: 10.1089/ten.TEA.2017.0084. Epub 2017 Jun 15.

6.

Therapeutic inhibition of miR-375 attenuates post-myocardial infarction inflammatory response and left ventricular dysfunction via PDK-1-AKT signalling axis.

Garikipati VNS, Verma SK, Jolardarashi D, Cheng Z, Ibetti J, Cimini M, Tang Y, Khan M, Yue Y, Benedict C, Nickoloff E, Truongcao MM, Gao E, Krishnamurthy P, Goukassian DA, Koch WJ, Kishore R.

Cardiovasc Res. 2017 Jul 1;113(8):938-949. doi: 10.1093/cvr/cvx052.

PMID:
28371849
7.

Coordinated Activation of VEGF/VEGFR-2 and PPARδ Pathways by a Multi-Component Chinese Medicine DHI Accelerated Recovery from Peripheral Arterial Disease in Type 2 Diabetic Mice.

He S, Zhao T, Guo H, Meng Y, Qin G, Goukassian DA, Han J, Gao X, Zhu Y.

PLoS One. 2016 Dec 8;11(12):e0167305. doi: 10.1371/journal.pone.0167305. eCollection 2016.

8.

Corrigendum to "Particle Radiation-Induced Nontargeted Effects in Bone-Marrow-Derived Endothelial Progenitor Cells".

Sasi SP, Park D, Muralidharan S, Wage J, Kiladjian A, Onufrak J, Enderling H, Yan X, Goukassian DA.

Stem Cells Int. 2016;2016:7958361. doi: 10.1155/2016/7958361. Epub 2016 Jan 6.

9.

Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.

Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA.

Front Oncol. 2015 Nov 25;5:255. doi: 10.3389/fonc.2015.00255. eCollection 2015.

10.

Correction: Therapeutic Non-Toxic Doses of TNF Induce Significant Regression in TNFR2-p75 Knockdown Lewis Lung Carcinoma Tumor Implants.

Sasi SP, Bae S, Song J, Perepletchikov A, Schneider D, Carrozza J, Yan X, Kishore R, Enderling H, Goukassian DA.

PLoS One. 2015 Nov 30;10(11):e0144213. doi: 10.1371/journal.pone.0144213. eCollection 2015. No abstract available.

11.

TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells.

Sasi SP, Song J, Park D, Enderling H, McDonald JT, Gee H, Garrity B, Shtifman A, Yan X, Walsh K, Natarajan M, Kishore R, Goukassian DA.

J Biol Chem. 2015 Nov 6;290(45):27014. doi: 10.1074/jbc.A114.567743. No abstract available.

12.

Correction: Cardiovascular Risks Associated with Low Dose Ionizing Particle Radiation.

Yan X, Sasi SP, Gee H, Lee J, Yang Y, Mehrzad R, Onufrak J, Song J, Enderling H, Agarwal A, Rahimi L, Morgan J, Wilson PF, Carrozza J, Walsh K, Kishore R, Goukassian DA.

PLoS One. 2015 Nov 6;10(11):e0142764. doi: 10.1371/journal.pone.0142764. eCollection 2015. No abstract available.

13.

Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.

Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA.

Front Oncol. 2015 Oct 14;5:231. doi: 10.3389/fonc.2015.00231. eCollection 2015. Review. Erratum in: Front Oncol. 2015;5:255.

14.

Low-dose radiation affects cardiac physiology: gene networks and molecular signaling in cardiomyocytes.

Coleman MA, Sasi SP, Onufrak J, Natarajan M, Manickam K, Schwab J, Muralidharan S, Peterson LE, Alekseyev YO, Yan X, Goukassian DA.

Am J Physiol Heart Circ Physiol. 2015 Dec 1;309(11):H1947-63. doi: 10.1152/ajpheart.00050.2015. Epub 2015 Sep 25.

15.

Particle Radiation-Induced Nontargeted Effects in Bone-Marrow-Derived Endothelial Progenitor Cells.

Sasi SP, Park D, Muralidharan S, Wage J, Kiladjian A, Onufrak J, Enderling H, Yan X, Goukassian DA.

Stem Cells Int. 2015;2015:496512. doi: 10.1155/2015/496512. Epub 2015 May 5. Erratum in: Stem Cells Int. 2016;2016:7958361.

16.

Inhibition of Sam68 triggers adipose tissue browning.

Zhou J, Cheng M, Boriboun C, Ardehali MM, Jiang C, Liu Q, Han S, Goukassian DA, Tang YL, Zhao TC, Zhao M, Cai L, Richard S, Kishore R, Qin G.

J Endocrinol. 2015 Jun;225(3):181-9. doi: 10.1530/JOE-14-0727. Epub 2015 May 1.

17.

Genetic deletion of TNFR2 augments inflammatory response and blunts satellite-cell-mediated recovery response in a hind limb ischemia model.

Sasi SP, Rahimi L, Yan X, Silver M, Qin G, Losordo DW, Kishore R, Goukassian DA.

FASEB J. 2015 Apr;29(4):1208-19. doi: 10.1096/fj.14-249813. Epub 2014 Dec 2.

18.

Cardiovascular risks associated with low dose ionizing particle radiation.

Yan X, Sasi SP, Gee H, Lee J, Yang Y, Mehrzad R, Onufrak J, Song J, Enderling H, Agarwal A, Rahimi L, Morgan J, Wilson PF, Carrozza J, Walsh K, Kishore R, Goukassian DA.

PLoS One. 2014 Oct 22;9(10):e110269. doi: 10.1371/journal.pone.0110269. eCollection 2014. Erratum in: PLoS One. 2015;10(11):e0142764.

19.

TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells.

Sasi SP, Song J, Park D, Enderling H, McDonald JT, Gee H, Garrity B, Shtifman A, Yan X, Walsh K, Natarajan M, Kishore R, Goukassian DA.

J Biol Chem. 2014 May 16;289(20):14178-93. doi: 10.1074/jbc.M114.567743. Epub 2014 Apr 7. Erratum in: J Biol Chem. 2015 Nov 6;290(45):27014.

20.

Therapeutic non-toxic doses of TNF induce significant regression in TNFR2-p75 knockdown Lewis lung carcinoma tumor implants.

Sasi SP, Bae S, Song J, Perepletchikov A, Schneider D, Carrozza J, Yan X, Kishore R, Enderling H, Goukassian DA.

PLoS One. 2014 Mar 24;9(3):e92373. doi: 10.1371/journal.pone.0092373. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e101647. PLoS One. 2015;10(11):e0144213.

21.

Divergent modification of low-dose ⁵⁶Fe-particle and proton radiation on skeletal muscle.

Shtifman A, Pezone MJ, Sasi SP, Agarwal A, Gee H, Song J, Perepletchikov A, Yan X, Kishore R, Goukassian DA.

Radiat Res. 2013 Nov;180(5):455-64. doi: 10.1667/RR3329.1. Epub 2013 Oct 17.

22.

Topical application of thymidine dinucleotide to newborn mice reduces and delays development of UV-induced melanomas.

Goukassian DA, Sharov A, Rhodes J, Coleman C, Eller MS, Sharova T, Bhawan J, Gilchrest BA.

J Invest Dermatol. 2012 Nov;132(11):2664-6. doi: 10.1038/jid.2012.176. Epub 2012 Jun 14. No abstract available.

23.

Breaking the 'harmony' of TNF-α signaling for cancer treatment.

Sasi SP, Yan X, Enderling H, Park D, Gilbert HY, Curry C, Coleman C, Hlatky L, Qin G, Kishore R, Goukassian DA.

Oncogene. 2012 Sep 13;31(37):4117-27. doi: 10.1038/onc.2011.567. Epub 2011 Dec 12.

24.

Tumor necrosis factor-α signaling via TNFR1/p55 is deleterious whereas TNFR2/p75 signaling is protective in adult infarct myocardium.

Kishore R, Tkebuchava T, Sasi SP, Silver M, Gilbert HY, Yoon YS, Park HY, Thorne T, Losordo DW, Goukassian DA.

Adv Exp Med Biol. 2011;691:433-48. doi: 10.1007/978-1-4419-6612-4_45. No abstract available.

25.

Inhibition of melanoma angiogenesis by telomere homolog oligonucleotides.

Coleman C, Levine D, Kishore R, Qin G, Thorne T, Lambers E, Sasi SP, Yaar M, Gilchrest BA, Goukassian DA.

J Oncol. 2010;2010:928628. doi: 10.1155/2010/928628. Epub 2010 Jun 28.

26.

Polypodium leucotomos extract decreases UV-induced Cox-2 expression and inflammation, enhances DNA repair, and decreases mutagenesis in hairless mice.

Zattra E, Coleman C, Arad S, Helms E, Levine D, Bord E, Guillaume A, El-Hajahmad M, Zwart E, van Steeg H, Gonzalez S, Kishore R, Goukassian DA.

Am J Pathol. 2009 Nov;175(5):1952-61. doi: 10.2353/ajpath.2009.090351. Epub 2009 Oct 1.

27.

Topical thymidine dinucleotide treatment reduces development of ultraviolet-induced basal cell carcinoma in Ptch-1+/- mice.

Arad S, Zattra E, Hebert J, Epstein EH Jr, Goukassian DA, Gilchrest BA.

Am J Pathol. 2008 May;172(5):1248-55. doi: 10.2353/ajpath.2008.071117. Epub 2008 Apr 10.

28.

Dietary lutein/zeaxanthin partially reduces photoaging and photocarcinogenesis in chronically UVB-irradiated Skh-1 hairless mice.

Astner S, Wu A, Chen J, Philips N, Rius-Diaz F, Parrado C, Mihm MC, Goukassian DA, Pathak MA, González S.

Skin Pharmacol Physiol. 2007;20(6):283-91. Epub 2007 Aug 24.

PMID:
17717424
29.

Quantification of inducible SOS-like photoprotective responses in human skin.

Arad S, Konnikov N, Goukassian DA, Gilchrest BA.

J Invest Dermatol. 2007 Nov;127(11):2629-36. Epub 2007 May 24.

30.

Tumor necrosis factor-alpha receptor p75 is required in ischemia-induced neovascularization.

Goukassian DA, Qin G, Dolan C, Murayama T, Silver M, Curry C, Eaton E, Luedemann C, Ma H, Asahara T, Zak V, Mehta S, Burg A, Thorne T, Kishore R, Losordo DW.

Circulation. 2007 Feb 13;115(6):752-62. Epub 2007 Jan 29.

PMID:
17261656
31.

T-oligos augment UV-induced protective responses in human skin.

Arad S, Konnikov N, Goukassian DA, Gilchrest BA.

FASEB J. 2006 Sep;20(11):1895-7. Epub 2006 Jul 28.

PMID:
16877521
32.

Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF.

Qin G, Kishore R, Dolan CM, Silver M, Wecker A, Luedemann CN, Thorne T, Hanley A, Curry C, Heyd L, Dinesh D, Kearney M, Martelli F, Murayama T, Goukassian DA, Zhu Y, Losordo DW.

Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11015-20. Epub 2006 Jul 11.

33.

Functional disruption of alpha4 integrin mobilizes bone marrow-derived endothelial progenitors and augments ischemic neovascularization.

Qin G, Ii M, Silver M, Wecker A, Bord E, Ma H, Gavin M, Goukassian DA, Yoon YS, Papayannopoulou T, Asahara T, Kearney M, Thorne T, Curry C, Eaton L, Heyd L, Dinesh D, Kishore R, Zhu Y, Losordo DW.

J Exp Med. 2006 Jan 23;203(1):153-63. Epub 2006 Jan 9.

34.

T-oligo treatment decreases constitutive and UVB-induced COX-2 levels through p53- and NFkappaB-dependent repression of the COX-2 promoter.

Marwaha V, Chen YH, Helms E, Arad S, Inoue H, Bord E, Kishore R, Sarkissian RD, Gilchrest BA, Goukassian DA.

J Biol Chem. 2005 Sep 16;280(37):32379-88. Epub 2005 Jul 26.

35.
36.

Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice.

Goukassian DA, Helms E, van Steeg H, van Oostrom C, Bhawan J, Gilchrest BA.

Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3933-8. Epub 2004 Mar 3.

37.

Engineering the response to vascular injury: divergent effects of deregulated E2F1 expression on vascular smooth muscle cells and endothelial cells result in endothelial recovery and inhibition of neointimal growth.

Goukassian DA, Kishore R, Krasinski K, Dolan C, Luedemann C, Yoon YS, Kearney M, Hanley A, Ma H, Asahara T, Isner JM, Losordo DW.

Circ Res. 2003 Jul 25;93(2):162-9. Epub 2003 Jun 26.

PMID:
12829616
38.

DNA oligonucleotide treatment corrects the age-associated decline in DNA repair capacity.

Goukassian DA, Bagheri S, el-Keeb L, Eller MS, Gilchrest BA.

FASEB J. 2002 May;16(7):754-6. Epub 2002 Mar 26.

PMID:
11923222
39.

Thymidine dinucleotide mimics the effect of solar simulated irradiation on p53 and p53-regulated proteins.

Goukassian DA, Eller MS, Yaar M, Gilchrest BA.

J Invest Dermatol. 1999 Jan;112(1):25-31.

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