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Items: 1 to 50 of 82

1.

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.

Korkut A, Zaidi S, Kanchi RS, Rao S, Gough NR, Schultz A, Li X, Lorenzi PL, Berger AC, Robertson G, Kwong LN, Datto M, Roszik J, Ling S, Ravikumar V, Manyam G, Rao A, Shelley S, Liu Y, Ju Z, Hansel D, de Velasco G, Pennathur A, Andersen JB, O'Rourke CJ, Ohshiro K, Jogunoori W, Nguyen BN, Li S, Osmanbeyoglu HU, Ajani JA, Mani SA, Houseman A, Wiznerowicz M, Chen J, Gu S, Ma W, Zhang J, Tong P, Cherniack AD, Deng C, Resar L; Cancer Genome Atlas Research Network, Weinstein JN, Mishra L, Akbani R.

Cell Syst. 2018 Oct 24;7(4):422-437.e7. doi: 10.1016/j.cels.2018.08.010. Epub 2018 Sep 26.

2.

Focus Issue: Cancer-Beyond tumor genetics to protein landscapes.

Ferrarelli LK, Gough NR.

Sci Signal. 2017 Mar 14;10(470). pii: eaan0430. doi: 10.1126/scisignal.aan0430.

PMID:
28292948
3.

Pseudophosphatase as E3 ubiquitin ligase inhibitor.

Gough NR.

Sci Signal. 2017 Feb 14;10(466). pii: eaam9607. doi: 10.1126/scisignal.aam9607.

PMID:
28196911
4.

Daily oxygen rhythms.

Gough NR.

Sci Signal. 2017 Jan 31;10(464). pii: eaam8695. doi: 10.1126/scisignal.aam8695.

PMID:
28143912
5.

Lysosomes get into the action.

Gough NR.

Sci Signal. 2017 Jan 24;10(463). pii: eaam8020. doi: 10.1126/scisignal.aam8020.

PMID:
28119458
6.

Translational complex for differentiation.

Gough NR.

Sci Signal. 2017 Jan 17;10(462). pii: eaam7563. doi: 10.1126/scisignal.aam7563.

PMID:
28096509
7.

Channeling pain through GPCRs.

Gough NR.

Science. 2017 Jan 13;355(6321):143-144. doi: 10.1126/science.355.6321.143-h. No abstract available.

PMID:
28082564
8.

New connections: NHERF gates activity.

Gough NR.

Sci Signal. 2017 Jan 10;10(461). pii: eaam7242. doi: 10.1126/scisignal.aam7242.

PMID:
28074011
9.

Tumors block pain with CXCL12.

Gough NR.

Sci Signal. 2017 Jan 10;10(461). pii: eaam7233. doi: 10.1126/scisignal.aam7233.

PMID:
28074010
10.

Placing the nuclear pore in the metformin mechanism of action.

Gough NR.

Sci Signal. 2017 Jan 3;10(460). pii: eaam6836. doi: 10.1126/scisignal.aam6836. No abstract available.

PMID:
28049772
11.

Emerging roles for organelles in cellular regulation.

Gough NR.

Sci Signal. 2016 Dec 6;9(457):eg11.

PMID:
27923911
12.

A kinase makes its own inhibitor.

Gough NR.

Science. 2016 Nov 18;354(6314):843-845. No abstract available.

PMID:
27856891
13.

Unveiling the molecular details of plant signaling.

Gough NR.

Sci Signal. 2016 Sep 20;9(446):eg9. doi: 10.1126/scisignal.aai9302.

PMID:
27649738
14.

Signaling proteins in the spotlight.

Gough NR.

Sci Signal. 2016 Jul 12;9(436):eg8. doi: 10.1126/scisignal.aah4114.

PMID:
27405977
15.

Focus Issue: New insights in GPCR to G protein signaling.

Gough NR.

Sci Signal. 2016 Apr 12;9(423):eg6. doi: 10.1126/scisignal.aaf7642.

PMID:
27072653
16.

Beyond canonical: The Wnt and β-catenin story.

Moon RT, Gough NR.

Sci Signal. 2016 Apr 5;9(422):eg5. doi: 10.1126/scisignal.aaf6192.

PMID:
27048563
17.

Leveraging signaling research to understand and treat disease.

Yaffe MB, Gough NR.

Sci Signal. 2016 Mar 29;9(421):eg4. doi: 10.1126/scisignal.aaf6275.

PMID:
27025875
18.

Focus Issue: The ins and outs of ORAI in immune cells.

Gough NR.

Sci Signal. 2016 Mar 8;9(418):eg3. doi: 10.1126/scisignal.aaf4957.

PMID:
26956481
19.

Focus Issue: Cell biology meets cancer therapy.

Gough NR.

Sci Signal. 2016 Feb 16;9(415):eg2. doi: 10.1126/scisignal.aaf3386.

PMID:
26884597
20.

The computable cell: A step toward personalized medicine.

Gough NR.

Sci Signal. 2015 Dec 22;8(408):eg6. doi: 10.1126/scisignal.aae0544.

PMID:
26696628
21.

Criteria for biological reproducibility: what does "n" mean?

Naegle K, Gough NR, Yaffe MB.

Sci Signal. 2015 Apr 7;8(371):fs7. doi: 10.1126/scisignal.aab1125. Review.

PMID:
25852186
22.

Focus issue: Tackling reproducibility and accuracy in cell signaling experiments.

Gough NR.

Sci Signal. 2015 Apr 7;8(371):eg4. doi: 10.1126/scisignal.aab1831.

PMID:
25852184
23.

Focus issue: TGF-β and the mesenchymal transition in physiology and disease.

Ferrarelli LK, Gough NR.

Sci Signal. 2014 Sep 30;7(345):eg3. doi: 10.1126/scisignal.2005909.

PMID:
25270256
24.

2013: Signaling breakthroughs of the year.

Berndt JD, Gough NR.

Sci Signal. 2014 Jan 7;7(307):eg1. doi: 10.1126/scisignal.2005013.

PMID:
24399293
25.

Focus issue: uncovering the mechanisms of neurological disease.

Ferrarelli LK, Gough NR.

Sci Signal. 2013 Jul 9;6(283):eg4. doi: 10.1126/scisignal.2004456. Review.

26.

Focus issue: From genomic mutations to oncogenic pathways.

Gough NR.

Sci Signal. 2013 Mar 26;6(268):eg3. doi: 10.1126/scisignal.2004149.

27.

2012: Signaling breakthroughs of the year.

Yaffe MB, Gough NR.

Sci Signal. 2013 Jan 1;6(256):eg1. doi: 10.1126/scisignal.2003881. No abstract available.

28.

Focus issue: signaling architecture from domains to complexes.

Wong W, Gough NR.

Sci Signal. 2012 May 29;5(226):eg7. doi: 10.1126/scisignal.2003235.

29.

Focus issue: TOR signaling, a tale of two complexes.

Gough NR.

Sci Signal. 2012 Mar 27;5(217):eg4. doi: 10.1126/scisignal.2003044.

30.

Focus issue: Wnt and β-catenin signaling in development and disease.

Gough NR.

Sci Signal. 2012 Jan 10;5(206):eg2. doi: 10.1126/scisignal.2002806.

31.

Focus issue: recruiting players for a game of ERK.

Gough NR.

Sci Signal. 2011 Oct 25;4(196):eg9. doi: 10.1126/scisignal.2002601.

32.

Focus issue: series on computational and systems biology.

Gough NR.

Sci Signal. 2011 Sep 6;4(189):eg8. doi: 10.1126/scisignal.2002478.

33.

Focus issue: Cracking the G protein-coupled receptor code.

Gough NR.

Sci Signal. 2011 Aug 2;4(185):eg7. doi: 10.1126/scisignal.2002388. Review.

34.

Focus issue: choreographing the dance of the mitotic kinases.

Gough NR.

Sci Signal. 2011 Jun 28;4(179):eg5. doi: 10.1126/scisignal.2002280. Review.

35.

Focus issue: Rendering resistance futile.

Adler EM, Gough NR.

Sci Signal. 2011 Mar 29;4(166):eg3. doi: 10.1126/scisignal.2002014.

36.

Focus issue: conquering the data mountain.

Gough NR, Yaffe MB.

Sci Signal. 2011 Feb 15;4(160):eg2. doi: 10.1126/scisignal.2001871.

37.

Focus issue: endocrine signaling from clinic to cell.

Gough NR.

Sci Signal. 2010 Oct 12;3(143):eg9. doi: 10.1126/scisignal.3143eg9.

38.

Focus issue: Evolution III--domains for change.

Gough NR.

Sci Signal. 2010 Sep 14;3(139):eg8. doi: 10.1126/scisignal.3139eg8.

39.

Focus issue: systems analysis of protein phosphorylation.

Gough NR, Foley JF.

Sci Signal. 2010 Aug 31;3(137):eg6. doi: 10.1126/scisignal.3137eg6.

40.

Focus issue: the evolution of complexity.

Gough NR, Wong W.

Sci Signal. 2010 Jun 29;3(128):eg5. doi: 10.1126/scisignal.3128eg5.

41.

Focus issue: teaching tools and learning opportunities.

Gough NR.

Sci Signal. 2010 Apr 27;3(119):eg3. doi: 10.1126/scisignal.3119eg3.

42.

Focus issue: external and internal regulators of immune responses.

Foley JF, Gough NR.

Sci Signal. 2010 Jan 19;3(105):eg2. doi: 10.1126/scisignal.3105eg2.

43.

Focus issue: addressing complicated questions in neuroscience.

Gough NR.

Sci Signal. 2009 Oct 20;2(93):eg13. doi: 10.1126/scisignal.293eg13.

44.

Training for peer review.

Gough NR.

Sci Signal. 2009 Aug 25;2(85):tr2. doi: 10.1126/scisignal.285tr2.

45.

Focus issue: unraveling signaling complexity.

Gough NR, Foley JF.

Sci Signal. 2009 Jul 28;2(81):eg10. doi: 10.1126/scisignal.281eg10.

46.

Focus Issue: demystifying mTOR signaling.

Gough NR.

Sci Signal. 2009 Apr 21;2(67):eg5. doi: 10.1126/scisignal.267eg5.

47.

Focus issue: the protein dynamics of cell signaling.

Wong W, Gough NR.

Sci Signal. 2009 Apr 14;2(66):eg4. doi: 10.1126/scisignal.266eg4.

48.

Focus issue: an expanding world for TGF-beta signaling.

Gough NR.

Sci Signal. 2008 Nov 18;1(46):eg8. doi: 10.1126/scisignal.146eg8.

49.

Focus issue: from input to output--are all paths equal?

Gough NR.

Sci Signal. 2008 Oct 21;1(42):eg6. doi: 10.1126/scisignal.142eg6.

50.

Hear it, watch it, read it.

Gough NR.

Sci Signal. 2008 Mar 25;1(12):eg2. doi: 10.1126/stke.112eg2.

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