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Items: 22


Evaluation of proteomic biomarkers associated with circulating microparticles as an effective means to stratify the risk of spontaneous preterm birth.

Cantonwine DE, Zhang Z, Rosenblatt K, Goudy KS, Doss RC, Ezrin AM, Page G, Brohman B, McElrath TF.

Am J Obstet Gynecol. 2016 May;214(5):631.e1-631.e11. doi: 10.1016/j.ajog.2016.02.005. Epub 2016 Feb 11.


Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs.

Akbarpour M, Goudy KS, Cantore A, Russo F, Sanvito F, Naldini L, Annoni A, Roncarolo MG.

Sci Transl Med. 2015 May 27;7(289):289ra81. doi: 10.1126/scitranslmed.aaa3032.


Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice.

Annoni A, Cantore A, Della Valle P, Goudy K, Akbarpour M, Russo F, Bartolaccini S, D'Angelo A, Roncarolo MG, Naldini L.

EMBO Mol Med. 2013 Nov;5(11):1684-97. doi: 10.1002/emmm.201302857. Epub 2013 Sep 16.


Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity.

Goudy K, Aydin D, Barzaghi F, Gambineri E, Vignoli M, Ciullini Mannurita S, Doglioni C, Ponzoni M, Cicalese MP, Assanelli A, Tommasini A, Brigida I, Dellepiane RM, Martino S, Olek S, Aiuti A, Ciceri F, Roncarolo MG, Bacchetta R.

Clin Immunol. 2013 Mar;146(3):248-61. doi: 10.1016/j.clim.2013.01.004. Epub 2013 Jan 24.


Immune responses in liver-directed lentiviral gene therapy.

Annoni A, Goudy K, Akbarpour M, Naldini L, Roncarolo MG.

Transl Res. 2013 Apr;161(4):230-40. doi: 10.1016/j.trsl.2012.12.018. Epub 2013 Jan 26. Review.


The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells.

Gregori S, Goudy KS, Roncarolo MG.

Front Immunol. 2012 Feb 29;3:30. doi: 10.3389/fimmu.2012.00030. eCollection 2012.


Manipulating Immune Tolerance with Micro-RNA Regulated Gene Therapy.

Goudy KS, Annoni A, Naldini L, Roncarolo MG.

Front Microbiol. 2011 Nov 14;2:221. doi: 10.3389/fmicb.2011.00221. eCollection 2011.


Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk.

Mátrai J, Cantore A, Bartholomae CC, Annoni A, Wang W, Acosta-Sanchez A, Samara-Kuko E, De Waele L, Ma L, Genovese P, Damo M, Arens A, Goudy K, Nichols TC, von Kalle C, L Chuah MK, Roncarolo MG, Schmidt M, Vandendriessche T, Naldini L.

Hepatology. 2011 May;53(5):1696-707. doi: 10.1002/hep.24230.


Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity.

Goudy KS, Johnson MC, Garland A, Li C, Samulski RJ, Wang B, Tisch R.

Eur J Immunol. 2011 May;41(5):1480-1490. doi: 10.1002/eji.201040890. Epub 2011 Apr 20.


Inducible adeno-associated virus-mediated IL-2 gene therapy prevents autoimmune diabetes.

Goudy KS, Johnson MC, Garland A, Li C, Samulski RJ, Wang B, Tisch R.

J Immunol. 2011 Mar 15;186(6):3779-86. doi: 10.4049/jimmunol.1001422. Epub 2011 Feb 11.


Leadership in these challenging times. Reflections on leadership during challenging times.

Robinson C, Goudy K.

Front Health Serv Manage. 2009 Winter;26(2):21-6. No abstract available.


Cellular immune response to cryptic epitopes during therapeutic gene transfer.

Li C, Goudy K, Hirsch M, Asokan A, Fan Y, Alexander J, Sun J, Monahan P, Seiber D, Sidney J, Sette A, Tisch R, Frelinger J, Samulski RJ.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10770-4. doi: 10.1073/pnas.0902269106. Epub 2009 Jun 16.


Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo.

Li C, Hirsch M, DiPrimio N, Asokan A, Goudy K, Tisch R, Samulski RJ.

J Virol. 2009 Jul;83(13):6817-24. doi: 10.1128/JVI.00278-09. Epub 2009 Apr 15.


The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice.

Pop SM, Wong CP, He Q, Wang Y, Wallet MA, Goudy KS, Tisch R.

Diabetes. 2007 May;56(5):1395-402. Epub 2007 Feb 22.


Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets.

Wong CP, Stevens R, Long B, Li L, Wang Y, Wallet MA, Goudy KS, Frelinger JA, Tisch R.

J Immunol. 2007 Feb 1;178(3):1388-95.


Immunotherapy for the prevention and treatment of type 1 diabetes.

Goudy KS, Tisch R.

Int Rev Immunol. 2005 Sep-Dec;24(5-6):307-26. Review.


Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice.

Song S, Goudy K, Campbell-Thompson M, Wasserfall C, Scott-Jorgensen M, Wang J, Tang Q, Crawford JM, Ellis TM, Atkinson MA, Flotte TR.

Gene Ther. 2004 Jan;11(2):181-6.


Glucose-responsive expression of the human insulin promoter in HepG2 human hepatoma cells.

Burkhardt BR, Loiler SA, Anderson JA, Kilberg MS, Crawford JM, Flotte TR, Goudy KS, Ellis TM, Atkinson M.

Ann N Y Acad Sci. 2003 Nov;1005:237-41.


Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.

Goudy KS, Burkhardt BR, Wasserfall C, Song S, Campbell-Thompson ML, Brusko T, Powers MA, Clare-Salzler MJ, Sobel ES, Ellis TM, Flotte TR, Atkinson MA.

J Immunol. 2003 Sep 1;171(5):2270-8.


Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

Zhang YC, Pileggi A, Agarwal A, Molano RD, Powers M, Brusko T, Wasserfall C, Goudy K, Zahr E, Poggioli R, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick H, Flotte T, Ellis TM, Ricordi C, Inverardi L, Atkinson MA.

Diabetes. 2003 Mar;52(3):708-16.


Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice.

Goudy K, Song S, Wasserfall C, Zhang YC, Kapturczak M, Muir A, Powers M, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Ellis TM, Flotte TR, Atkinson MA.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13913-8.

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