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Items: 1 to 50 of 261

1.

Microtubule inhibitors containing immunostimulatory agents promote cancer immunochemotherapy by inhibiting tubulin polymerization and tryptophan-2,3-dioxygenase.

Hua S, Chen F, Gou S.

Eur J Med Chem. 2019 Dec 5;187:111949. doi: 10.1016/j.ejmech.2019.111949. [Epub ahead of print]

PMID:
31830637
2.

Platinum-Based Modification of Styrylbenzylsulfones as Multifunctional Antitumor Agents: Targeting RAS-RAF Pathway, Enhancing Antitumor Activity and Overcoming Multidrug Resistance.

Liu Z, Wang M, Wang HS, Fang L, Gou S.

J Med Chem. 2019 Dec 10. doi: 10.1021/acs.jmedchem.9b01223. [Epub ahead of print]

PMID:
31820986
3.

Kinin B1 Receptor Is Important in the Pathogenesis of Myeloperoxidase-Specific ANCA GN.

Hu P, Su H, Xiao H, Gou SJ, Herrera CA, Alba MA, Kakoki M, Falk RJ, Jennette JC.

J Am Soc Nephrol. 2019 Nov 26. pii: ASN.2019010032. doi: 10.1681/ASN.2019010032. [Epub ahead of print]

PMID:
31772138
4.

Study on the effects of different dimerization positions on biological activity of partial d-Amino acid substitution analogues of Anoplin.

Zhong C, Gou S, Liu T, Zhu Y, Zhu N, Liu H, Zhang Y, Xie J, Guo X, Ni J.

Microb Pathog. 2019 Nov 14;139:103871. doi: 10.1016/j.micpath.2019.103871. [Epub ahead of print]

PMID:
31733278
5.

Emerging JWA-targeted Pt(IV) prodrugs conjugated with CX-4945 to overcome chemo-immune-resistance.

Chen F, Pei S, Wang X, Zhu Q, Gou S.

Biochem Biophys Res Commun. 2019 Nov 5. pii: S0006-291X(19)32100-X. doi: 10.1016/j.bbrc.2019.10.184. [Epub ahead of print]

PMID:
31703842
6.

Self-Assembly Supramolecular Systems Based on Guanidinium Salts Modified Hyperbranched Polyamidoamine and Cationic Acrylamide Copolymers.

Wu Q, Gou S, Fei Y, Yang X, Liu M, Huang J.

Polymers (Basel). 2019 Oct 31;11(11). pii: E1781. doi: 10.3390/polym11111781.

7.

Antimicrobial peptides conjugated with fatty acids on the side chain of D-amino acid promises antimicrobial potency against multidrug-resistant bacteria.

Zhong C, Zhu N, Zhu Y, Liu T, Gou S, Xie J, Yao J, Ni J.

Eur J Pharm Sci. 2020 Jan 1;141:105123. doi: 10.1016/j.ejps.2019.105123. Epub 2019 Oct 30.

PMID:
31676352
8.

A lysosome specific theranostic NO donor inhibits cancer cells by stimuli responsive molecular self-decomposition with an on-demand fluorescence pattern.

Hua W, Zhao J, Wang X, Pei S, Gou S.

Analyst. 2019 Nov 21;144(22):6681-6688. doi: 10.1039/c9an01746a. Epub 2019 Oct 10.

PMID:
31599280
9.

Malignant development in patients with oral potentially malignant disorders detected through nationwide screening: Outcomes of 5-year follow-up at a single hospital.

Chiang WF, Liu SY, Lin JF, Chiu SF, Gou SB, Chiou CT, Chang CH.

Head Neck. 2019 Oct 7. doi: 10.1002/hed.25973. [Epub ahead of print]

PMID:
31589002
10.

[Changes of surgical interventions on necrotizing pancreatitis].

Gou SM, Wu HS, Zhang YS, Xiong JX, Zhou F, Zhao G, Yin T, Yang M, Peng T, Cui J, Zhou W, Guo Y, Wang B, Liu ZQ, Zhou XX, Wang CY.

Zhonghua Wai Ke Za Zhi. 2019 Oct 1;57(10):14-18. doi: 10.3760/cma.j.issn.0529-5815.2019.10.004. Chinese.

PMID:
31510727
11.

Dual-targeting antitumor conjugates derived from platinum(IV) prodrugs and microtubule inhibitor CA-4 significantly exhibited potent ability to overcome cisplatin resistance.

Huang X, Wang M, Wang C, Hu W, You Q, Yang Y, Yu C, Liao Z, Gou S, Wang H.

Bioorg Chem. 2019 Nov;92:103236. doi: 10.1016/j.bioorg.2019.103236. Epub 2019 Aug 30.

PMID:
31494328
12.

Design and synthesis of new N-terminal fatty acid modified-antimicrobial peptide analogues with potent in vitro biological activity.

Zhong C, Liu T, Gou S, He Y, Zhu N, Zhu Y, Wang L, Liu H, Zhang Y, Yao J, Ni J.

Eur J Med Chem. 2019 Nov 15;182:111636. doi: 10.1016/j.ejmech.2019.111636. Epub 2019 Aug 20.

PMID:
31466017
13.

Spectrum-effect relationship between HPLC fingerprints and bioactive components of Radix Hedysari on increasing the peak bone mass of rat.

Chen XY, Gou SH, Shi ZQ, Xue ZY, Feng SL.

J Pharm Anal. 2019 Aug;9(4):266-273. doi: 10.1016/j.jpha.2018.10.004. Epub 2018 Nov 1.

14.

Novel conjugates with dual suppression of glutathione S-transferases and tryptophan-2,3-dioxygenase activities for improving hepatocellular carcinoma therapy.

Hua S, Wang X, Chen F, Gou S.

Bioorg Chem. 2019 Nov;92:103191. doi: 10.1016/j.bioorg.2019.103191. Epub 2019 Aug 10.

PMID:
31445192
15.

Gradient regularized convolutional neural networks for low-dose CT image enhancement.

Gou S, Liu W, Jiao C, Liu H, Gu Y, Zhang X, Lee J, Jiao L.

Phys Med Biol. 2019 Aug 21;64(16):165017. doi: 10.1088/1361-6560/ab325e.

PMID:
31433791
16.

End-to-End Ensemble Learning by Exploiting the Correlation Between Individuals and Weights.

Mao S, Lin W, Jiao L, Gou S, Chen JW.

IEEE Trans Cybern. 2019 Aug 14. doi: 10.1109/TCYB.2019.2931071. [Epub ahead of print]

PMID:
31425063
17.

Promoting antitumor efficacy by suppressing hypoxia via nano self-assembly of two irinotecan-based dual drug conjugates having a HIF-1α inhibitor.

Zhang B, Huang X, Wang H, Gou S.

J Mater Chem B. 2019 Sep 11;7(35):5352-5362. doi: 10.1039/c9tb00541b.

PMID:
31402355
18.

A Population-Based Study of the Incidence and Survival of Anorectal Gastrointestinal Stromal Tumor.

Liu Z, Wu S, Gou S, Li Y, Wu H, Li Y.

Med Sci Monit. 2019 Jul 21;25:5408-5417. doi: 10.12659/MSM.915967.

19.

Silk fibroin-based nanotherapeutics: application in the treatment of colonic diseases.

Gou S, Huang Y, Sung J, Xiao B, Merlin D.

Nanomedicine (Lond). 2019 Sep;14(17):2373-2378. doi: 10.2217/nnm-2019-0058. Epub 2019 Jul 10.

PMID:
31290366
20.

Beclin1 affected by DN604 upregulates chemo-sensitivity of cervix SiHa cancer cells via inhibiting CK2-MRN-DSBs repair.

Chen F, Sun S, Liu N, Pei S, Zhu Q, Wang X, Gou S.

Anticancer Drugs. 2019 Sep;30(8):774-783. doi: 10.1097/CAD.0000000000000804.

PMID:
31274516
21.

Efficient base editing for multiple genes and loci in pigs using base editors.

Xie J, Ge W, Li N, Liu Q, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L.

Nat Commun. 2019 Jun 28;10(1):2852. doi: 10.1038/s41467-019-10421-8.

22.

Toll-like receptors as potential therapeutic targets in kidney diseases.

Ren Q, Cheng L, Yi J, Ma L, Pan J, Gou SJ, Fu P.

Curr Med Chem. 2019 Jun 3. doi: 10.2174/0929867325666190603110907. [Epub ahead of print]

PMID:
31161985
23.

Multi-bioresponsive silk fibroin-based nanoparticles with on-demand cytoplasmic drug release capacity for CD44-targeted alleviation of ulcerative colitis.

Gou S, Huang Y, Wan Y, Ma Y, Zhou X, Tong X, Huang J, Kang Y, Pan G, Dai F, Xiao B.

Biomaterials. 2019 Aug;212:39-54. doi: 10.1016/j.biomaterials.2019.05.012. Epub 2019 May 9.

PMID:
31103945
24.

Er:YAG fractional laser ablation for cutaneous co-delivery of pentoxifylline and d-α-tocopherol succinate: A new approach for topical treatment of radiation-induced skin fibrosis.

Gou S, Del Rio-Sancho S, Singhal M, Laubach HJ, Kalia YN.

Eur J Pharm Sci. 2019 Jul 1;135:22-31. doi: 10.1016/j.ejps.2019.05.007. Epub 2019 May 10.

PMID:
31078643
25.

Light-activated ruthenium (II)-bicalutamide prodrugs for prostate cancer.

Zhao J, Liu N, Sun S, Gou S, Wang X, Wang Z, Li X, Zhang W.

J Inorg Biochem. 2019 Jul;196:110684. doi: 10.1016/j.jinorgbio.2019.03.024. Epub 2019 Mar 30.

PMID:
31054419
26.

Prognostic accuracy of the serum lactate level, the SOFA score and the qSOFA score for mortality among adults with Sepsis.

Liu Z, Meng Z, Li Y, Zhao J, Wu S, Gou S, Wu H.

Scand J Trauma Resusc Emerg Med. 2019 Apr 30;27(1):51. doi: 10.1186/s13049-019-0609-3.

27.

The relationship between thyroid dysfunction and nephrotic syndrome: a clinicopathological study.

Li LZ, Hu Y, Ai SL, Cheng L, Liu J, Morris E, Li Y, Gou SJ, Fu P.

Sci Rep. 2019 Apr 23;9(1):6421. doi: 10.1038/s41598-019-42905-4.

28.

Shape constrained fully convolutional DenseNet with adversarial training for multiorgan segmentation on head and neck CT and low-field MR images.

Tong N, Gou S, Yang S, Cao M, Sheng K.

Med Phys. 2019 Jun;46(6):2669-2682. doi: 10.1002/mp.13553. Epub 2019 May 6.

PMID:
31002188
29.

Novel 7-formyl-naphthyridyl-ureas derivatives as potential selective FGFR4 inhibitors: Design, synthesis, and biological activity studies.

Sun C, Fang L, Zhang X, Gao P, Gou S.

Bioorg Med Chem. 2019 May 15;27(10):1932-1941. doi: 10.1016/j.bmc.2019.04.018. Epub 2019 Apr 10.

PMID:
30987781
30.

[Clinicopathological significance of poorly differentiated clusters in colorectal adenocarcinoma].

Yang LL, Gou SQ, Wang JS, Qi Q, Huang WB.

Zhonghua Bing Li Xue Za Zhi. 2019 Apr 8;48(4):276-281. doi: 10.3760/cma.j.issn.0529-5807.2019.04.003. Chinese.

PMID:
30955262
31.

Pt(IV) hybrids containing a TDO inhibitor serve as potential anticancer immunomodulators.

Hua S, Chen F, Wang X, Wang Y, Gou S.

J Inorg Biochem. 2019 Jun;195:130-140. doi: 10.1016/j.jinorgbio.2019.02.004. Epub 2019 Feb 12.

PMID:
30952082
32.

Pomalidomide hybrids act as proteolysis targeting chimeras: Synthesis, anticancer activity and B-Raf degradation.

Chen H, Chen F, Pei S, Gou S.

Bioorg Chem. 2019 Jun;87:191-199. doi: 10.1016/j.bioorg.2019.03.035. Epub 2019 Mar 19.

PMID:
30901674
33.

Modulation of drug release by decoration with Pluronic F127 to improve anti-colon cancer activity of electrospun fibrous meshes.

Ma P, Gou S, Ma Y, Chen Q, Zhu S, Chen J, Kang Y, Xiao B.

Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:591-598. doi: 10.1016/j.msec.2019.01.130. Epub 2019 Jan 30.

PMID:
30889734
34.

Multifunctional platinum(IV) complexes as immunostimulatory agents to promote cancer immunochemotherapy by inhibiting tryptophan-2,3-dioxygenase.

Hua S, Chen F, Xu G, Gou S.

Eur J Med Chem. 2019 May 1;169:29-41. doi: 10.1016/j.ejmech.2019.02.063. Epub 2019 Mar 3.

PMID:
30852385
35.

Porous Polymeric Microparticles as an Oral Drug Platform for Effective Ulcerative Colitis Treatment.

Zhou X, Chen Q, Ma Y, Huang Y, Gou S, Xiao B.

J Pharm Sci. 2019 Jul;108(7):2238-2242. doi: 10.1016/j.xphs.2019.02.001. Epub 2019 Feb 16.

PMID:
30779888
36.

A cisplatin-based platinum(IV) prodrug containing a glutathione s-transferase inhibitor to reverse cisplatin-resistance in non-small cell lung cancer.

Chen H, Wang X, Gou S.

J Inorg Biochem. 2019 Apr;193:133-142. doi: 10.1016/j.jinorgbio.2019.01.014. Epub 2019 Jan 29.

PMID:
30731264
37.

Dinuclear Organoruthenium Complexes Exhibiting Antiproliferative Activity through DNA Damage and a Reactive-Oxygen-Species-Mediated Endoplasmic Reticulum Stress Pathway.

Zhao J, Li S, Wang X, Xu G, Gou S.

Inorg Chem. 2019 Feb 4;58(3):2208-2217. doi: 10.1021/acs.inorgchem.8b03447. Epub 2019 Jan 24.

PMID:
30675781
38.

Construction of Dual Stimuli-Responsive Platinum(IV) Hybrids with NQO1 Targeting Ability and Overcoming Cisplatin Resistance.

Fang L, Qin X, Zhao J, Gou S.

Inorg Chem. 2019 Feb 4;58(3):2191-2200. doi: 10.1021/acs.inorgchem.8b03386. Epub 2019 Jan 18.

PMID:
30657321
39.

Stimuli-Responsive Luminescent Copper Nanoclusters in Alginate and Their Sensing Ability for Glucose.

Gou S, Shi YE, Li P, Wang H, Li T, Zhuang X, Li W, Wang Z.

ACS Appl Mater Interfaces. 2019 Feb 13;11(6):6561-6567. doi: 10.1021/acsami.8b20835. Epub 2019 Jan 31.

PMID:
30656937
40.
41.

SHR-A1403, a novel c-Met antibody-drug conjugate, exerts encouraging anti-tumor activity in c-Met-overexpressing models.

Yang CY, Wang L, Sun X, Tang M, Quan HT, Zhang LS, Lou LG, Gou SH.

Acta Pharmacol Sin. 2019 Jul;40(7):971-979. doi: 10.1038/s41401-018-0198-0. Epub 2019 Jan 14.

PMID:
30643210
42.

Oral administration of colitis tissue-accumulating porous nanoparticles for ulcerative colitis therapy.

Chen Q, Gou S, Ma P, Song H, Zhou X, Huang Y, Kwon Han M, Wan Y, Kang Y, Xiao B.

Int J Pharm. 2019 Feb 25;557:135-144. doi: 10.1016/j.ijpharm.2018.12.046. Epub 2018 Dec 27.

PMID:
30594685
43.
44.

Facile Fabrication of Oxidation-Responsive Polymeric Nanoparticles for Effective Anticancer Drug Delivery.

Huang Y, Chen Q, Ma P, Song H, Ma X, Ma Y, Zhou X, Gou S, Xu Z, Chen J, Xiao B.

Mol Pharm. 2019 Jan 7;16(1):49-59. doi: 10.1021/acs.molpharmaceut.8b00634. Epub 2018 Dec 5.

PMID:
30485109
45.

Preclinical pharmacokinetics of a novel anti-c-Met antibody-drug conjugate, SHR-A1403, in rodents and non-human primates.

Yang C, Zhao X, Sun X, Li J, Wang W, Zhang L, Gou S.

Xenobiotica. 2019 Sep;49(9):1097-1105. doi: 10.1080/00498254.2018.1534030. Epub 2019 Jan 4.

PMID:
30299189
46.

Chemically induced degradation of CK2 by proteolysis targeting chimeras based on a ubiquitin-proteasome pathway.

Chen H, Chen F, Liu N, Wang X, Gou S.

Bioorg Chem. 2018 Dec;81:536-544. doi: 10.1016/j.bioorg.2018.09.005. Epub 2018 Sep 12.

PMID:
30245235
47.

Large-Deformation Image Registration of CT-TEE for Surgical Navigation of Congenital Heart Disease.

Gou S, Chen L, Gu Y, Huang L, Huang M, Zhuang J.

Comput Math Methods Med. 2018 Jul 30;2018:4687376. doi: 10.1155/2018/4687376. eCollection 2018.

48.

Pairing of Luminescent Switch with Electrochromism for Quasi-Solid-State Dual-Function Smart Windows.

Wang Z, Zhu M, Gou S, Pang Z, Wang Y, Su Y, Huang Y, Weng Q, Schmidt OG, Xu J.

ACS Appl Mater Interfaces. 2018 Sep 19;10(37):31697-31703. doi: 10.1021/acsami.8b10790. Epub 2018 Sep 5.

PMID:
30136581
49.

Fully automatic multi-organ segmentation for head and neck cancer radiotherapy using shape representation model constrained fully convolutional neural networks.

Tong N, Gou S, Yang S, Ruan D, Sheng K.

Med Phys. 2018 Oct;45(10):4558-4567. doi: 10.1002/mp.13147. Epub 2018 Sep 19.

50.

Immunoglobulin G4-related Kidney Disease Associated With Autoimmune Hemolytic Anemia.

Gou SJ, Yu SB, Qiu HY, Hu ZX.

Iran J Kidney Dis. 2018 Jul;12(4):243-246.

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