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Items: 24


Workshop on challenges, insights, and future directions for mouse and humanized models in cancer immunology and immunotherapy: a report from the associated programs of the 2016 annual meeting for the Society for Immunotherapy of cancer.

Zloza A, Karolina Palucka A, Coussens LM, Gotwals PJ, Headley MB, Jaffee EM, Lund AW, Sharpe AH, Sznol M, Wainwright DA, Wong KK, Bosenberg MW.

J Immunother Cancer. 2017 Sep 19;5(1):77. doi: 10.1186/s40425-017-0278-6.


Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis.

Murray HW, Flanders KC, Donaldson DD, Sypek JP, Gotwals PJ, Liu J, Ma X.

Infect Immun. 2005 Jul;73(7):3903-11.


A monoclonal antibody to alpha1beta1 blocks antigen-induced airway responses in sheep.

Abraham WM, Ahmed A, Serebriakov I, Carmillo AN, Ferrant J, de Fougerolles AR, Garber EA, Gotwals PJ, Koteliansky VE, Taylor F, Lobb RR.

Am J Respir Crit Care Med. 2004 Jan 1;169(1):97-104. Epub 2003 Oct 24.


Cell and molecular regulation of endothelin-1 production during hepatic wound healing.

Shao R, Shi Z, Gotwals PJ, Koteliansky VE, George J, Rockey DC.

Mol Biol Cell. 2003 Jun;14(6):2327-41. Epub 2003 Apr 17.


Transforming growth factor-beta-dependent events in vascular remodeling following arterial injury.

Ryan ST, Koteliansky VE, Gotwals PJ, Lindner V.

J Vasc Res. 2003 Jan-Feb;40(1):37-46.


Interference with TGF-beta1 and -beta3 in tumor stroma lowers tumor interstitial fluid pressure independently of growth in experimental carcinoma.

Lammerts E, Roswall P, Sundberg C, Gotwals PJ, Koteliansky VE, Reed RK, Heldin NE, Rubin K.

Int J Cancer. 2002 Dec 10;102(5):453-62.


Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

Muraoka RS, Dumont N, Ritter CA, Dugger TC, Brantley DM, Chen J, Easterly E, Roebuck LR, Ryan S, Gotwals PJ, Koteliansky V, Arteaga CL.

J Clin Invest. 2002 Jun;109(12):1551-9.


The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing.

Liao YF, Gotwals PJ, Koteliansky VE, Sheppard D, Van De Water L.

J Biol Chem. 2002 Apr 26;277(17):14467-74. Epub 2002 Feb 11.


TGF-beta is a critical mediator of acute lung injury.

Pittet JF, Griffiths MJ, Geiser T, Kaminski N, Dalton SL, Huang X, Brown LA, Gotwals PJ, Koteliansky VE, Matthay MA, Sheppard D.

J Clin Invest. 2001 Jun;107(12):1537-44.


Effect of antibody against integrin alpha4 on bleomycin-induced pulmonary fibrosis in mice.

Wang Q, Wang Y, Hyde DM, Gotwals PJ, Lobb RR, Ryan ST, Giri SN.

Biochem Pharmacol. 2000 Dec 15;60(12):1949-58.


Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice.

Zheng H, Wang J, Koteliansky VE, Gotwals PJ, Hauer-Jensen M.

Gastroenterology. 2000 Nov;119(5):1286-96.


Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis.

de Fougerolles AR, Sprague AG, Nickerson-Nutter CL, Chi-Rosso G, Rennert PD, Gardner H, Gotwals PJ, Lobb RR, Koteliansky VE.

J Clin Invest. 2000 Mar;105(6):721-9.


Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters.

Wang Q, Wang Y, Hyde DM, Gotwals PJ, Koteliansky VE, Ryan ST, Giri SN.

Thorax. 1999 Sep;54(9):805-12.


Divalent cations stabilize the alpha 1 beta 1 integrin I domain.

Gotwals PJ, Chi-Rosso G, Ryan ST, Sizing I, Zafari M, Benjamin C, Singh J, Venyaminov SY, Pepinsky RB, Koteliansky V.

Biochemistry. 1999 Jun 29;38(26):8280-8.


Crystal structure of the alpha1beta1 integrin I-domain: insights into integrin I-domain function.

Nolte M, Pepinsky RB, Venyaminov SYu, Koteliansky V, Gotwals PJ, Karpusas M.

FEBS Lett. 1999 Jun 11;452(3):379-85.


Soluble transforming growth factor-beta type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth.

Smith JD, Bryant SR, Couper LL, Vary CP, Gotwals PJ, Koteliansky VE, Lindner V.

Circ Res. 1999 May 28;84(10):1212-22.


Epitope mapping of a function-blocking beta 1 integrin antibody by phage display.

Ryan ST, Chi-Rosso G, Bonnycastle LL, Scott JK, Koteliansky V, Pollard S, Gotwals PJ.

Cell Adhes Commun. 1998 Jan;5(1):75-82.


Fibronectin type III repeats mediate RGD-independent adhesion and signaling through activated beta1 integrins.

Chi-Rosso G, Gotwals PJ, Yang J, Ling L, Jiang K, Chao B, Baker DP, Burkly LC, Fawell SE, Koteliansky VE.

J Biol Chem. 1997 Dec 12;272(50):31447-52.


A functional monoclonal antibody recognizing the human alpha 1-integrin I-domain.

Fabbri M, Castellani P, Gotwals PJ, Kotelianski V, Zardi L, Zocchi MR.

Tissue Antigens. 1996 Jul;48(1):47-51.


The alpha1beta1 integrin is expressed during neointima formation in rat arteries and mediates collagen matrix reorganization.

Gotwals PJ, Chi-Rosso G, Lindner V, Yang J, Ling L, Fawell SE, Koteliansky VE.

J Clin Invest. 1996 Jun 1;97(11):2469-77.


Drosophila PS1 integrin is a laminin receptor and differs in ligand specificity from PS2.

Gotwals PJ, Fessler LI, Wehrli M, Hynes RO.

Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11447-51.


Drosophila integrins and their ligands.

Gotwals PJ, Paine-Saunders SE, Stark KA, Hynes RO.

Curr Opin Cell Biol. 1994 Oct;6(5):734-9. Review.


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