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Items: 34


The Drosophila odorant-binding protein 28a is involved in the detection of the floral odour ß-ionone.

Gonzalez D, Rihani K, Neiers F, Poirier N, Fraichard S, Gotthard G, Chertemps T, Maïbèche M, Ferveur JF, Briand L.

Cell Mol Life Sci. 2019 Sep 28. doi: 10.1007/s00018-019-03300-4. [Epub ahead of print]


Specific radiation damage is a lesser concern at room temperature.

Gotthard G, Aumonier S, De Sanctis D, Leonard G, von Stetten D, Royant A.

IUCrJ. 2019 Jun 12;6(Pt 4):665-680. doi: 10.1107/S205225251900616X. eCollection 2019 Jul 1.


Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.

Gozzi GJ, Gonzalez D, Boudesco C, Dias AMM, Gotthard G, Uyanik B, Dondaine L, Marcion G, Hermetet F, Denis C, Hardy L, Suzanne P, Douhard R, Jego G, Dubrez L, Demidov ON, Neiers F, Briand L, Sopková-de Oliveira Santos J, Voisin-Chiret AS, Garrido C.

Cell Death Differ. 2019 May 8. doi: 10.1038/s41418-019-0343-4. [Epub ahead of print]


Structure Solution of the Fluorescent Protein Cerulean Using MeshAndCollect.

Hutin S, Santoni G, Zander U, Foos N, Aumonier S, Gotthard G, Royant A, Mueller-Dieckmann C, Leonard G.

J Vis Exp. 2019 Mar 19;(145). doi: 10.3791/58594.


Dynamics of a family of cyan fluorescent proteins probed by incoherent neutron scattering.

Golub M, Guillon V, Gotthard G, Zeller D, Martinez N, Seydel T, Koza MM, Lafaye C, Clavel D, von Stetten D, Royant A, Peters J.

J R Soc Interface. 2019 Mar 29;16(152):20180848. doi: 10.1098/rsif.2018.0848.


Tailing miniSOG: structural bases of the complex photophysics of a flavin-binding singlet oxygen photosensitizing protein.

Torra J, Lafaye C, Signor L, Aumonier S, Flors C, Shu X, Nonell S, Gotthard G, Royant A.

Sci Rep. 2019 Feb 20;9(1):2428. doi: 10.1038/s41598-019-38955-3.


Visuospatial word search task only effective at disrupting declarative memory when prediction error is present during retrieval.

Gotthard GH, Gura H.

Neurobiol Learn Mem. 2018 Dec;156:80-85. doi: 10.1016/j.nlm.2018.11.003. Epub 2018 Nov 8.


Reconsolidation of appetitive odor discrimination requires protein synthesis only when reactivation includes prediction error.

Gotthard GH, Kenney L, Zucker A.

Behav Neurosci. 2018 Jun;132(3):131-137. doi: 10.1037/bne0000242.


Tracking the route of molecular oxygen in O2-tolerant membrane-bound [NiFe] hydrogenase.

Kalms J, Schmidt A, Frielingsdorf S, Utesch T, Gotthard G, von Stetten D, van der Linden P, Royant A, Mroginski MA, Carpentier P, Lenz O, Scheerer P.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2229-E2237. doi: 10.1073/pnas.1712267115. Epub 2018 Feb 20.


Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.

Jacquet P, Hiblot J, Daudé D, Bergonzi C, Gotthard G, Armstrong N, Chabrière E, Elias M.

Sci Rep. 2017 Dec 1;7(1):16745. doi: 10.1038/s41598-017-16841-0.


Chromophore Isomer Stabilization Is Critical to the Efficient Fluorescence of Cyan Fluorescent Proteins.

Gotthard G, von Stetten D, Clavel D, Noirclerc-Savoye M, Royant A.

Biochemistry. 2017 Dec 12;56(49):6418-6422. doi: 10.1021/acs.biochem.7b01088. Epub 2017 Nov 27.


Recombinant expression of Mimivirus L725 ORFan gene product.

Sobhy H, Gotthard G, Chabrière E, Raoult D, Colson P.

Acta Virol. 2017;61(1):123-126. doi: 10.4149/av_2017_01_116.


Structural analysis of the bright monomeric yellow-green fluorescent protein mNeonGreen obtained by directed evolution.

Clavel D, Gotthard G, von Stetten D, De Sanctis D, Pasquier H, Lambert GG, Shaner NC, Royant A.

Acta Crystallogr D Struct Biol. 2016 Dec 1;72(Pt 12):1298-1307. Epub 2016 Nov 30.


mScarlet: a bright monomeric red fluorescent protein for cellular imaging.

Bindels DS, Haarbosch L, van Weeren L, Postma M, Wiese KE, Mastop M, Aumonier S, Gotthard G, Royant A, Hink MA, Gadella TW Jr.

Nat Methods. 2017 Jan;14(1):53-56. doi: 10.1038/nmeth.4074. Epub 2016 Nov 21.


Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP.

Colletier JP, Sliwa M, Gallat FX, Sugahara M, Guillon V, Schirò G, Coquelle N, Woodhouse J, Roux L, Gotthard G, Royant A, Uriarte LM, Ruckebusch C, Joti Y, Byrdin M, Mizohata E, Nango E, Tanaka T, Tono K, Yabashi M, Adam V, Cammarata M, Schlichting I, Bourgeois D, Weik M.

J Phys Chem Lett. 2016 Mar 3;7(5):882-7. doi: 10.1021/acs.jpclett.5b02789. Epub 2016 Feb 25.


Surface plasmon resonance imaging of pathogens: the Yersinia pestis paradigm.

Huynh HT, Gotthard G, Terras J, Aboudharam G, Drancourt M, Chabrière E.

BMC Res Notes. 2015 Jun 24;8:259. doi: 10.1186/s13104-015-1236-3.


SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase.

Bzdrenga J, Hiblot J, Gotthard G, Champion C, Elias M, Chabriere E.

BMC Res Notes. 2014 Jun 3;7:333. doi: 10.1186/1756-0500-7-333.


Ancestral mutations as a tool for solubilizing proteins: The case of a hydrophobic phosphate-binding protein.

Gonzalez D, Hiblot J, Darbinian N, Miller JC, Gotthard G, Amini S, Chabriere E, Elias M.

FEBS Open Bio. 2014 Jan 3;4:121-7. doi: 10.1016/j.fob.2013.12.006. eCollection 2014.


Long-range DHPS mutations unexpectedly increase Mycobacterium chimaera susceptibility to sulfonamides.

Gotthard G, Muhammed Ameen S, Drancourt M, Chabriere E.

J Glob Antimicrob Resist. 2013 Dec;1(4):181-188. doi: 10.1016/j.jgar.2013.05.003. Epub 2013 Aug 1.


Structural and enzymatic characterization of the phosphotriesterase OPHC2 from Pseudomonas pseudoalcaligenes.

Gotthard G, Hiblot J, Gonzalez D, Elias M, Chabriere E.

PLoS One. 2013 Nov 4;8(11):e77995. doi: 10.1371/journal.pone.0077995. eCollection 2013.


Crystallization and preliminary X-ray diffraction analysis of the lactonase VmoLac from Vulcanisaeta moutnovskia.

Hiblot J, Gotthard G, Champion C, Chabriere E, Elias M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1235-8. doi: 10.1107/S1744309113024846. Epub 2013 Oct 17.


Crystallization and preliminary X-ray diffraction analysis of a high-affinity phosphate-binding protein endowed with phosphatase activity from Pseudomonas aeruginosa PAO1.

Djeghader A, Gotthard G, Suh A, Gonzalez D, Scott K, Chabriere E, Elias M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Oct;69(Pt 10):1143-6. doi: 10.1107/S1744309113024172. Epub 2013 Sep 28.


Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPox.

Hiblot J, Gotthard G, Elias M, Chabriere E.

PLoS One. 2013 Sep 23;8(9):e75272. doi: 10.1371/journal.pone.0075272. eCollection 2013.


Crystallization and preliminary X-ray diffraction analysis of a DING protein from Pseudomonas aeruginosa PA14.

Djeghader A, Gotthard G, Suh A, Gonzalez D, Scott K, Elias M, Chabriere E.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):425-9. doi: 10.1107/S1744309113005356. Epub 2013 Mar 28.


Crystallization and preliminary X-ray diffraction analysis of the organophosphorus hydrolase OPHC2 from Pseudomonas pseudoalcaligenes.

Gotthard G, Hiblot J, Gonzalez D, Chabrière E, Elias M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jan 1;69(Pt 1):73-6. doi: 10.1107/S174430911205049X. Epub 2012 Dec 25.


Characterisation of the organophosphate hydrolase catalytic activity of SsoPox.

Hiblot J, Gotthard G, Chabriere E, Elias M.

Sci Rep. 2012;2:779. doi: 10.1038/srep00779. Epub 2012 Nov 8.


Structural and enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus.

Hiblot J, Gotthard G, Chabriere E, Elias M.

PLoS One. 2012;7(10):e47028. doi: 10.1371/journal.pone.0047028. Epub 2012 Oct 10.


The level of DING proteins is increased in HIV-infected patients: in vitro and in vivo studies.

Djeghader A, Aragonès G, Darbinian N, Elias M, Gonzalez D, García-Heredia A, Beltrán-Debón R, Kaminski R, Gotthard G, Hiblot J, Rull A, Rohr O, Schwartz C, Alonso-Villaverde C, Joven J, Camps J, Chabriere E.

PLoS One. 2012;7(3):e33062. doi: 10.1371/journal.pone.0033062. Epub 2012 Mar 9.


Human-Phosphate-Binding-Protein inhibits HIV-1 gene transcription and replication.

Cherrier T, Elias M, Jeudy A, Gotthard G, Le Douce V, Hallay H, Masson P, Janossy A, Candolfi E, Rohr O, Chabrière E, Schwartz C.

Virol J. 2011 Jul 15;8:352. doi: 10.1186/1743-422X-8-352.


Crystallization and preliminary X-ray diffraction analysis of the hyperthermophilic Sulfolobus islandicus lactonase.

Gotthard G, Hiblot J, Elias M, Chabrière E.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Mar 1;67(Pt 3):354-7. doi: 10.1107/S1744309110053819. Epub 2011 Feb 25.


Extinction of appetitive learning is disrupted by cycloheximide and propranolol in the sand maze in rats.

Cohen J, Gotthard GH.

Neurobiol Learn Mem. 2011 May;95(4):484-90. doi: 10.1016/j.nlm.2011.02.011. Epub 2011 Mar 1.


Structural insights and ab initio sequencing within the DING proteins family.

Elias M, Liebschner D, Gotthard G, Chabriere E.

J Synchrotron Radiat. 2011 Jan;18(1):45-9. doi: 10.1107/S0909049510036009. Epub 2010 Nov 5.


Eukaryotic DING proteins are endogenous: an immunohistological study in mouse tissues.

Collombet JM, Elias M, Gotthard G, Four E, Renault F, Joffre A, Baubichon D, Rochu D, Chabrière E.

PLoS One. 2010 Feb 8;5(2):e9099. doi: 10.1371/journal.pone.0009099.


Cycloheximide produces amnesia for extinction and reconsolidation in an appetitive odor discrimination task in rats.

Gotthard GH, Knoppel AB.

Neurobiol Learn Mem. 2010 Jan;93(1):127-31. doi: 10.1016/j.nlm.2009.09.002. Epub 2009 Sep 15.


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