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Sexual dimorphism and heightened conditional expression in a sexually selected weapon in the Asian rhinoceros beetle.

Zinna R, Emlen D, Lavine LC, Johns A, Gotoh H, Niimi T, Dworkin I.

Mol Ecol. 2018 Oct 24. doi: 10.1111/mec.14907. [Epub ahead of print]


Optically transparent, high-toughness elastomer using a polyrotaxane cross-linker as a molecular pulley.

Gotoh H, Liu C, Imran AB, Hara M, Seki T, Mayumi K, Ito K, Takeoka Y.

Sci Adv. 2018 Oct 12;4(10):eaat7629. doi: 10.1126/sciadv.aat7629. eCollection 2018 Oct.


NG2 expression in NG2 glia is regulated by binding of SoxE and bHLH transcription factors to a Cspg4 intronic enhancer.

Gotoh H, Wood WM, Patel KD, Factor DC, Boshans LL, Nomura T, Tesar PJ, Ono K, Nishiyama A.

Glia. 2018 Oct 10. doi: 10.1002/glia.23521. [Epub ahead of print]


Rhinoceros beetle horn development reveals deep parallels with dung beetles.

Ohde T, Morita S, Shigenobu S, Morita J, Mizutani T, Gotoh H, Zinna RA, Nakata M, Ito Y, Wada K, Kitano Y, Yuzaki K, Toga K, Mase M, Kadota K, Rushe J, Lavine LC, Emlen DJ, Niimi T.

PLoS Genet. 2018 Oct 4;14(10):e1007651. doi: 10.1371/journal.pgen.1007651. eCollection 2018 Oct.


The hepcidin-25/erythroferrone ratio predicts improvement of anemia in hemodialysis patients treated with ferric citrate hydrate.

Hara M, Nakamura Y, Suzuki H, Asao R, Nakamura M, Nishida K, Kenmotsu S, Inagaki M, Tsuji M, Kiuchi Y, Ohsawa I, Goto Y, Gotoh H.

Nephrology (Carlton). 2018 Sep 21. doi: 10.1111/nep.13495. [Epub ahead of print]


Identification of liver fibrosis using the hepatic vein waveform in patients with Fontan circulation.

Nakatsuka T, Soroida Y, Nakagawa H, Shindo T, Sato M, Soma K, Nakagomi R, Kobayashi T, Endo M, Hikita H, Sato M, Gotoh H, Iwai T, Yasui M, Shinozaki-Ushiku A, Shiraga K, Asakai H, Hirata Y, Fukayama M, Ikeda H, Yatomi Y, Tateishi R, Inuzuka R, Koike K.

Hepatol Res. 2018 Sep 4. doi: 10.1111/hepr.13248. [Epub ahead of print]


Genetic mapping of a male factor subfertility locus on mouse chromosome 4.

Gotoh H, Miura I, Wakana S.

Mamm Genome. 2018 Oct;29(9-10):663-669. doi: 10.1007/s00335-018-9773-4. Epub 2018 Aug 31.


Linagliptin inhibits lipopolysaccharide-induced inflammation in human U937 monocytes.

Yamadera S, Nakamura Y, Inagaki M, Kenmotsu S, Nohara T, Sato N, Oguchi T, Tsuji M, Ohsawa I, Gotoh H, Goto Y, Yura A, Kiuchi Y, Iwai S.

Inflamm Regen. 2018 Aug 20;38:13. doi: 10.1186/s41232-018-0071-z. eCollection 2018.


Birthdate-dependent heterogeneity of oculomotor neurons is involved in transmedian migration in the developing mouse midbrain.

Kawano K, Gotoh H, Nomura T, Ono K.

J Chem Neuroanat. 2018 Dec;94:32-38. doi: 10.1016/j.jchemneu.2018.08.003. Epub 2018 Aug 16.


Dynamic Control of the Coupling between Dark and Bright Excitons with Vibrational Strain.

Ohta R, Okamoto H, Tawara T, Gotoh H, Yamaguchi H.

Phys Rev Lett. 2018 Jun 29;120(26):267401. doi: 10.1103/PhysRevLett.120.267401.


Anisotropy of cell division and epithelial sheet bending via apical constriction shape the complex folding pattern of beetle horn primordia.

Adachi H, Matsuda K, Niimi T, Inoue Y, Kondo S, Gotoh H.

Mech Dev. 2018 Aug;152:32-37. doi: 10.1016/j.mod.2018.06.003. Epub 2018 Jun 18.


Molecular Characterization of Eye Pigmentation-Related ABC Transporter Genes in the Ladybird Beetle Harmonia axyridis Reveals Striking Gene Duplication of the white Gene.

Tsuji T, Gotoh H, Morita S, Hirata J, Minakuchi Y, Yaginuma T, Toyoda A, Niimi T.

Zoolog Sci. 2018 Jun;35(3):260-267. doi: 10.2108/zs170166.


Eradication of hepatitis C virus is associated with the attenuation of steatosis as evaluated using a controlled attenuation parameter.

Shimizu K, Soroida Y, Sato M, Hikita H, Kobayashi T, Endo M, Sato M, Gotoh H, Iwai T, Tateishi R, Koike K, Yatomi Y, Ikeda H.

Sci Rep. 2018 May 18;8(1):7845. doi: 10.1038/s41598-018-26293-9.


Multi-petahertz electron interference in Cr:Al2O3 solid-state material.

Mashiko H, Chisuga Y, Katayama I, Oguri K, Masuda H, Takeda J, Gotoh H.

Nat Commun. 2018 Apr 18;9(1):1468. doi: 10.1038/s41467-018-03885-7.


Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain.

Yamashita W, Takahashi M, Kikkawa T, Gotoh H, Osumi N, Ono K, Nomura T.

Development. 2018 Apr 16;145(8). pii: dev159764. doi: 10.1242/dev.159764.


Recent advances in understanding the mechanisms of sexually dimorphic plasticity: insights from beetle weapons and future directions.

Zinna RA, Gotoh H, Kojima T, Niimi T.

Curr Opin Insect Sci. 2018 Feb;25:35-41. doi: 10.1016/j.cois.2017.11.009. Epub 2017 Nov 24. Review.


Opn5L1 is a retinal receptor that behaves as a reverse and self-regenerating photoreceptor.

Sato K, Yamashita T, Ohuchi H, Takeuchi A, Gotoh H, Ono K, Mizuno M, Mizutani Y, Tomonari S, Sakai K, Imamoto Y, Wada A, Shichida Y.

Nat Commun. 2018 Mar 28;9(1):1255. doi: 10.1038/s41467-018-03603-3.


Species-Specific Mechanisms of Neuron Subtype Specification Reveal Evolutionary Plasticity of Amniote Brain Development.

Nomura T, Yamashita W, Gotoh H, Ono K.

Cell Rep. 2018 Mar 20;22(12):3142-3151. doi: 10.1016/j.celrep.2018.02.086.


Gastrorenal shunt: a cause of hyperammonemia.

Nakamura Y, Ohsawa I, Goto Y, Gotoh H.

Clin Case Rep. 2017 Dec 15;6(1):240-241. doi: 10.1002/ccr3.1323. eCollection 2018 Jan.


The Fat-Dachsous signaling pathway regulates growth of horns in Trypoxylus dichotomus, but does not affect horn allometry.

Hust J, Lavine MD, Worthington AM, Zinna R, Gotoh H, Niimi T, Lavine L.

J Insect Physiol. 2018 Feb - Mar;105:85-94. doi: 10.1016/j.jinsphys.2018.01.006. Epub 2018 Jan 31.


Drift-Induced Enhancement of Cubic Dresselhaus Spin-Orbit Interaction in a Two-Dimensional Electron Gas.

Kunihashi Y, Sanada H, Tanaka Y, Gotoh H, Onomitsu K, Nakagawara K, Kohda M, Nitta J, Sogawa T.

Phys Rev Lett. 2017 Nov 3;119(18):187703. doi: 10.1103/PhysRevLett.119.187703. Epub 2017 Oct 31.


[Evaluation of Radiochromic Gel Dosimeter and Optical CT].

Yonehara M, Wakana R, Sakakibara K, Kotoku J, Kobayashi T, Gotoh H.

Igaku Butsuri. 2017;37(2):117-121. doi: 10.11323/jjmp.37.2_117. Japanese.


The Impact of Human Parvovirus B19 Infection on Heart Failure and Anemia with Reference to Iron Metabolism Markers in an Adult Woman.

Nakamura Y, Ohsawa I, Goto Y, Namba H, Dodo Y, Tsuji M, Kiuchi Y, Inagaki M, Gotoh H.

Intern Med. 2018 Feb 1;57(3):403-407. doi: 10.2169/internalmedicine.8809-17. Epub 2017 Nov 1.


Clinical Features of Hereditary and Mast Cell-mediated Angioedema Focusing on the Differential Diagnosis in Japanese Patients.

Ohsawa I, Honda D, Hisada A, Inoshita H, Onda-Tsueshita K, Mano S, Sato N, Nakamura Y, Shimizu T, Gotoh H, Goto Y, Suzuki Y, Tomino Y.

Intern Med. 2018 Feb 1;57(3):319-324. doi: 10.2169/internalmedicine.8624-16. Epub 2017 Nov 1.


Disappearance of perihepatic lymph node enlargement after hepatitis C viral eradication with direct-acting antivirals.

Hikita H, Sato M, Endo M, Sato M, Soroida Y, Kobayashi T, Gotoh H, Iwai T, Nakagomi R, Tateishi R, Komuro T, Sone S, Koike K, Yatomi Y, Ikeda H.

J Viral Hepat. 2018 Apr;25(4):329-334. doi: 10.1111/jvh.12819. Epub 2017 Dec 8.


Complex furrows in a 2D epithelial sheet code the 3D structure of a beetle horn.

Matsuda K, Gotoh H, Tajika Y, Sushida T, Aonuma H, Niimi T, Akiyama M, Inoue Y, Kondo S.

Sci Rep. 2017 Oct 24;7(1):13939. doi: 10.1038/s41598-017-14170-w.


Vitamin E-Coated Dialyzer Inhibits Oxidative Stress.

Yamadera S, Nakamura Y, Inagaki M, Ohsawa I, Gotoh H, Goto Y, Sato N, Oguchi T, Gomi Y, Tsuji M, Kiuchi Y, Iwai S.

Blood Purif. 2017;44(4):288-293. doi: 10.1159/000478971. Epub 2017 Oct 25.


Computational wave dynamics for innovative design of coastal structures.

Gotoh H, Okayasu A.

Proc Jpn Acad Ser B Phys Biol Sci. 2017;93(8):525-546. doi: 10.2183/pjab.93.034.


Origin of Oligodendrocytes in the Vertebrate Optic Nerve: A Review.

Ono K, Hirahara Y, Gotoh H, Nomura T, Takebayashi H, Yamada H, Ikenaka K.

Neurochem Res. 2018 Jan;43(1):186-194. doi: 10.1007/s11064-017-2404-8. Epub 2017 Oct 4. Review.


Ultrasound evaluation of liver stiffness: accuracy of ultrasound imaging for the prediction of liver cirrhosis as evaluated using a liver stiffness measurement.

Endo M, Soroida Y, Sato M, Kobayashi T, Hikita H, Sato M, Gotoh H, Iwai T, Sone S, Sasano T, Sumi Y, Koike K, Yatomi Y, Ikeda H.

J Med Dent Sci. 2017;64(2-3):27-34. doi: 10.11480/jmds.640301.


Denosumab for Male Hemodialysis Patients with Low Bone Mineral Density: A Case-Control Study.

Takami H, Washio K, Gotoh H.

Int J Nephrol. 2017;2017:6218129. doi: 10.1155/2017/6218129. Epub 2017 Aug 22.


Soy isoflavones inducing overt hypothyroidism in a patient with chronic lymphocytic thyroiditis: a case report.

Nakamura Y, Ohsawa I, Goto Y, Tsuji M, Oguchi T, Sato N, Kiuchi Y, Fukumura M, Inagaki M, Gotoh H.

J Med Case Rep. 2017 Sep 5;11(1):253. doi: 10.1186/s13256-017-1418-9.


The Future Vocation of Neural Stem Cells: Lineage Commitment in Brain Development and Evolution.

Nomura T, Gotoh H, Ono K.

Neurochem Res. 2018 Jan;43(1):153-156. doi: 10.1007/s11064-017-2380-z. Epub 2017 Aug 24. Review.


A novel imaging method for correlating 2D light microscopic data and 3D volume data based on block-face imaging.

Tajika Y, Murakami T, Iijima K, Gotoh H, Takahashi-Ikezawa M, Ueno H, Yoshimoto Y, Yorifuji H.

Sci Rep. 2017 Jun 16;7(1):3645. doi: 10.1038/s41598-017-03900-9.


Luteolin attenuates interleukin-6-mediated astrogliosis in human iPSC-derived neural aggregates: A candidate preventive substance for maternal immune activation-induced abnormalities.

Zuiki M, Chiyonobu T, Yoshida M, Maeda H, Yamashita S, Kidowaki S, Hasegawa T, Gotoh H, Nomura T, Ono K, Hosoi H, Morimoto M.

Neurosci Lett. 2017 Jul 13;653:296-301. doi: 10.1016/j.neulet.2017.06.004. Epub 2017 Jun 6.


Optical nonlinearity enhancement with graphene-decorated silicon waveguides.

Ishizawa A, Kou R, Goto T, Tsuchizawa T, Matsuda N, Hitachi K, Nishikawa T, Yamada K, Sogawa T, Gotoh H.

Sci Rep. 2017 Apr 12;7:45520. doi: 10.1038/srep45520.


Divergent Synthesis of Heteroatom-Centered 4,8,12-Triazatriangulenes.

Nakatsuka S, Gotoh H, Kinoshita K, Yasuda N, Hatakeyama T.

Angew Chem Int Ed Engl. 2017 Apr 24;56(18):5087-5090. doi: 10.1002/anie.201701246. Epub 2017 Mar 29.


Oligodendrocyte precursor cells in the mouse optic nerve originate in the preoptic area.

Ono K, Yoshii K, Tominaga H, Gotoh H, Nomura T, Takebayashi H, Ikenaka K.

Brain Struct Funct. 2017 Jul;222(5):2441-2448. doi: 10.1007/s00429-017-1394-2. Epub 2017 Mar 14.


Circulating TNF Receptors 1 and 2 Predict Mortality in Patients with End-stage Renal Disease Undergoing Dialysis.

Gohda T, Maruyama S, Kamei N, Yamaguchi S, Shibata T, Murakoshi M, Horikoshi S, Tomino Y, Ohsawa I, Gotoh H, Nojiri S, Suzuki Y.

Sci Rep. 2017 Mar 3;7:43520. doi: 10.1038/srep43520.


The function of appendage patterning genes in mandible development of the sexually dimorphic stag beetle.

Gotoh H, Zinna RA, Ishikawa Y, Miyakawa H, Ishikawa A, Sugime Y, Emlen DJ, Lavine LC, Miura T.

Dev Biol. 2017 Feb 1;422(1):24-32. doi: 10.1016/j.ydbio.2016.12.011. Epub 2016 Dec 16.


Linagliptin Has Wide-Ranging Anti-Inflammatory Points of Action in Human Umbilical Vein Endothelial Cells.

Nakamura Y, Inagaki M, Tsuji M, Gocho T, Handa K, Hasegawa H, Yura A, Kawakami T, Ohsawa I, Goto Y, Gotoh H, Kiuchi Y.

Jpn Clin Med. 2016 Dec 5;7:27-32. eCollection 2016.


Sulfatide species with various fatty acid chains in oligodendrocytes at different developmental stages determined by imaging mass spectrometry.

Hirahara Y, Wakabayashi T, Mori T, Koike T, Yao I, Tsuda M, Honke K, Gotoh H, Ono K, Yamada H.

J Neurochem. 2017 Feb;140(3):435-450. doi: 10.1111/jnc.13897. Epub 2016 Dec 15.


Glycogen serves as an energy source that maintains astrocyte cell proliferation in the neonatal telencephalon.

Gotoh H, Nomura T, Ono K.

J Cereb Blood Flow Metab. 2017 Jun;37(6):2294-2307. doi: 10.1177/0271678X16665380. Epub 2016 Jan 1.


Rapid and efficient gene delivery into the adult mouse brain via focal electroporation.

Nomura T, Nishimura Y, Gotoh H, Ono K.

Sci Rep. 2016 Jul 19;6:29817. doi: 10.1038/srep29817.


Molecular cloning and functional characterization of the sex-determination gene doublesex in the sexually dimorphic broad-horned beetle Gnatocerus cornutus (Coleoptera, Tenebrionidae).

Gotoh H, Ishiguro M, Nishikawa H, Morita S, Okada K, Miyatake T, Yaginuma T, Niimi T.

Sci Rep. 2016 Jul 11;6:29337. doi: 10.1038/srep29337.


Endocrine Control of Exaggerated Trait Growth in Rhinoceros Beetles.

Zinna R, Gotoh H, Brent CS, Dolezal A, Kraus A, Niimi T, Emlen D, Lavine LC.

Integr Comp Biol. 2016 Aug;56(2):247-59. doi: 10.1093/icb/icw042. Epub 2016 Jun 1. Review.


Ultralow-phase-noise millimetre-wave signal generator assisted with an electro-optics-modulator-based optical frequency comb.

Ishizawa A, Nishikawa T, Goto T, Hitachi K, Sogawa T, Gotoh H.

Sci Rep. 2016 May 17;6:24621. doi: 10.1038/srep24621.


Identification and functional analyses of sex determination genes in the sexually dimorphic stag beetle Cyclommatus metallifer.

Gotoh H, Zinna RA, Warren I, DeNieu M, Niimi T, Dworkin I, Emlen DJ, Miura T, Lavine LC.

BMC Genomics. 2016 Mar 22;17:250. doi: 10.1186/s12864-016-2522-8.


Pancreatic cysts in general population on ultrasonography: Prevalence and development of risk score.

Soroida Y, Sato M, Hikita H, Hagiwara S, Sato M, Gotoh H, Kato S, Iwai T, Yamazaki T, Yatomi Y, Sasano T, Ikeda H.

J Gastroenterol. 2016 Dec;51(12):1133-1140. Epub 2016 Mar 17.


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