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Items: 28

1.

Human adipose glycerol flux is regulated by a pH gate in AQP10.

Gotfryd K, Mósca AF, Missel JW, Truelsen SF, Wang K, Spulber M, Krabbe S, Hélix-Nielsen C, Laforenza U, Soveral G, Pedersen PA, Gourdon P.

Nat Commun. 2018 Nov 12;9(1):4749. doi: 10.1038/s41467-018-07176-z.

2.

Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT.

Merkle PS, Gotfryd K, Cuendet MA, Leth-Espensen KZ, Gether U, Loland CJ, Rand KD.

Sci Adv. 2018 May 11;4(5):eaar6179. doi: 10.1126/sciadv.aar6179. eCollection 2018 May.

3.

Purification and functional comparison of nine human Aquaporins produced in Saccharomyces cerevisiae for the purpose of biophysical characterization.

Bjørkskov FB, Krabbe SL, Nurup CN, Missel JW, Spulber M, Bomholt J, Molbaek K, Helix-Nielsen C, Gotfryd K, Gourdon P, Pedersen PA.

Sci Rep. 2017 Dec 4;7(1):16899. doi: 10.1038/s41598-017-17095-6.

4.

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR.

Erlendsson S, Gotfryd K, Larsen FH, Mortensen JS, Geiger MA, van Rossum BJ, Oschkinat H, Gether U, Teilum K, Loland CJ.

Elife. 2017 Jan 24;6. pii: e19314. doi: 10.7554/eLife.19314.

5.

The Environment Shapes the Inner Vestibule of LeuT.

Sohail A, Jayaraman K, Venkatesan S, Gotfryd K, Daerr M, Gether U, Loland CJ, Wanner KT, Freissmuth M, Sitte HH, Sandtner W, Stockner T.

PLoS Comput Biol. 2016 Nov 11;12(11):e1005197. doi: 10.1371/journal.pcbi.1005197. eCollection 2016 Nov.

6.

Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter:sodium symporter.

Billesbølle CB, Krüger MB, Shi L, Quick M, Li Z, Stolzenberg S, Kniazeff J, Gotfryd K, Mortensen JS, Javitch JA, Weinstein H, Loland CJ, Gether U.

J Biol Chem. 2015 Oct 30;290(44):26725-38. doi: 10.1074/jbc.M115.677658. Epub 2015 Sep 11.

7.

Grafted biomembranes containing membrane proteins--the case of the leucine transporter.

Jagalski V, Barker RD, Thygesen MB, Gotfryd K, Krüger MB, Shi L, Maric S, Bovet N, Moulin M, Haertlein M, Pomorski TG, Loland CJ, Cárdenas M.

Soft Matter. 2015 Oct 21;11(39):7707-11. doi: 10.1039/c5sm01490e. Epub 2015 Sep 1.

PMID:
26325086
8.

Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser.

Bublitz M, Nass K, Drachmann ND, Markvardsen AJ, Gutmann MJ, Barends TR, Mattle D, Shoeman RL, Doak RB, Boutet S, Messerschmidt M, Seibert MM, Williams GJ, Foucar L, Reinhard L, Sitsel O, Gregersen JL, Clausen JD, Boesen T, Gotfryd K, Wang KT, Olesen C, Møller JV, Nissen P, Schlichting I.

IUCrJ. 2015 Jun 11;2(Pt 4):409-20. doi: 10.1107/S2052252515008969. eCollection 2015 Jul 1.

9.

Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation.

Cho KH, Du Y, Scull NJ, Hariharan P, Gotfryd K, Loland CJ, Guan L, Byrne B, Kobilka BK, Chae PS.

Chemistry. 2015 Jul 6;21(28):10008-13. doi: 10.1002/chem.201501083. Epub 2015 May 26.

10.

Deoxycholate-Based Glycosides (DCGs) for Membrane Protein Stabilisation.

Bae HE, Gotfryd K, Thomas J, Hussain H, Ehsan M, Go J, Loland CJ, Byrne B, Chae PS.

Chembiochem. 2015 Jul 6;16(10):1454-9. doi: 10.1002/cbic.201500151. Epub 2015 May 7.

PMID:
25953685
11.

Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters.

Stolzenberg S, Quick M, Zhao C, Gotfryd K, Khelashvili G, Gether U, Loland CJ, Javitch JA, Noskov S, Weinstein H, Shi L.

J Biol Chem. 2015 May 29;290(22):13992-4003. doi: 10.1074/jbc.M114.625343. Epub 2015 Apr 13.

12.

Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study.

Cho KH, Husri M, Amin A, Gotfryd K, Lee HJ, Go J, Kim JW, Loland CJ, Guan L, Byrne B, Chae PS.

Analyst. 2015 May 7;140(9):3157-63. doi: 10.1039/c5an00240k. Epub 2015 Mar 27.

13.

Novel tripod amphiphiles for membrane protein analysis.

Chae PS, Kruse AC, Gotfryd K, Rana RR, Cho KH, Rasmussen SG, Bae HE, Chandra R, Gether U, Guan L, Kobilka BK, Loland CJ, Byrne B, Gellman SH.

Chemistry. 2013 Nov 11;19(46):15645-51. doi: 10.1002/chem.201301423. Epub 2013 Oct 2.

14.

A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter.

Rickhag M, Hansen FH, Sørensen G, Strandfelt KN, Andresen B, Gotfryd K, Madsen KL, Vestergaard-Klewe I, Ammendrup-Johnsen I, Eriksen J, Newman AH, Füchtbauer EM, Gomeza J, Woldbye DP, Wörtwein G, Gether U.

Nat Commun. 2013;4:1580. doi: 10.1038/ncomms2568. Erratum in: Nat Commun. 2013;4:2589.

15.

Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.

Chae PS, Rana RR, Gotfryd K, Rasmussen SG, Kruse AC, Cho KH, Capaldi S, Carlsson E, Kobilka B, Loland CJ, Gether U, Banerjee S, Byrne B, Lee JK, Gellman SH.

Chem Commun (Camb). 2013 Mar 21;49(23):2287-9. doi: 10.1039/c2cc36844g. Erratum in: Chem Commun (Camb). 2013 Dec 28;49(100):11821-2.

16.

A virtual high-throughput screening approach to the discovery of novel inhibitors of the bacterial leucine transporter, LeuT.

Simmons KJ, Gotfryd K, Billesbølle CB, Loland CJ, Gether U, Fishwick CW, Johnson AP.

Mol Membr Biol. 2013 Mar;30(2):184-94. doi: 10.3109/09687688.2012.710341. Epub 2012 Aug 21.

PMID:
22908980
17.

A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.

Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH.

Chemistry. 2012 Jul 27;18(31):9485-90. doi: 10.1002/chem.201200069. Epub 2012 Jun 22. No abstract available. Erratum in: Chemistry. 2013 Apr 15;19(16):4964.

18.

Iron inhibits respiratory burst of peritoneal phagocytes in vitro.

Gotfryd K, Jurek A, Kubit P, Klein A, Turyna B.

ISRN Urol. 2011;2011:605436. doi: 10.5402/2011/605436. Epub 2011 Dec 8.

19.

A peptide derived from the CD loop-D helix region of ciliary neurotrophic factor (CNTF) induces neuronal differentiation and survival by binding to the leukemia inhibitory factor (LIF) receptor and common cytokine receptor chain gp130.

Rathje M, Pankratova S, Nielsen J, Gotfryd K, Bock E, Berezin V.

Eur J Cell Biol. 2011 Dec;90(12):990-9. doi: 10.1016/j.ejcb.2011.08.001. Epub 2011 Oct 14.

PMID:
22000729
20.

The teratogenic potencies of valproic acid derivatives and their effects on biological end-points are related to changes in histone deacetylase and Erk1/2 activities.

Gotfryd K, Hansen M, Kawa A, Ellerbeck U, Nau H, Berezin V, Bock E, Walmod PS.

Basic Clin Pharmacol Toxicol. 2011 Sep;109(3):164-74. doi: 10.1111/j.1742-7843.2011.00702.x. Epub 2011 Apr 18.

21.

Tandem facial amphiphiles for membrane protein stabilization.

Chae PS, Gotfryd K, Pacyna J, Miercke LJ, Rasmussen SG, Robbins RA, Rana RR, Loland CJ, Kobilka B, Stroud R, Byrne B, Gether U, Gellman SH.

J Am Chem Soc. 2010 Dec 1;132(47):16750-2. doi: 10.1021/ja1072959. Epub 2010 Nov 4. Erratum in: J Am Chem Soc. 2013 Aug 28;135(34):12922.

22.

Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins.

Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, Gether U, Byrne B, Kobilka B, Gellman SH.

Nat Methods. 2010 Dec;7(12):1003-8. doi: 10.1038/nmeth.1526. Epub 2010 Oct 31.

23.

Cell type-specific anti-cancer properties of valproic acid: independent effects on HDAC activity and Erk1/2 phosphorylation.

Gotfryd K, Skladchikova G, Lepekhin EA, Berezin V, Bock E, Walmod PS.

BMC Cancer. 2010 Jul 21;10:383. doi: 10.1186/1471-2407-10-383.

24.

Neuroprotective properties of a novel, non-haematopoietic agonist of the erythropoietin receptor.

Pankratova S, Kiryushko D, Sonn K, Soroka V, Køhler LB, Rathje M, Gu B, Gotfryd K, Clausen O, Zharkovsky A, Bock E, Berezin V.

Brain. 2010 Aug;133(Pt 8):2281-94. doi: 10.1093/brain/awq101. Epub 2010 Apr 30.

PMID:
20435631
25.

Role of glial cell line-derived neurotrophic factor (GDNF)-neural cell adhesion molecule (NCAM) interactions in induction of neurite outgrowth and identification of a binding site for NCAM in the heel region of GDNF.

Nielsen J, Gotfryd K, Li S, Kulahin N, Soroka V, Rasmussen KK, Bock E, Berezin V.

J Neurosci. 2009 Sep 9;29(36):11360-76. doi: 10.1523/JNEUROSCI.3239-09.2009.

26.

Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family.

Ambjørn M, Asmussen JW, Lindstam M, Gotfryd K, Jacobsen C, Kiselyov VV, Moestrup SK, Penkowa M, Bock E, Berezin V.

J Neurochem. 2008 Jan;104(1):21-37. Epub 2007 Nov 6.

27.

Multiple effects of pentyl-4-yn-VPA enantiomers: from toxicity to short-term memory enhancement.

Gotfryd K, Owczarek S, Hoffmann K, Klementiev B, Nau H, Berezin V, Bock E, Walmod PS.

Neuropharmacology. 2007 Mar;52(3):764-78. Epub 2006 Nov 7.

PMID:
17095022
28.

Peritonitis-induced antitumor activity of peritoneal macrophages from uremic patients.

Turyna B, Jurek A, Gotfryd K, Siaśkiewicz A, Kubit P, Klein A.

Folia Histochem Cytobiol. 2004;42(3):147-53.

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