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Items: 1 to 50 of 117

1.

Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3.

Ronkina N, Schuster-Gossler K, Hansmann F, Kunze-Schumacher H, Sandrock I, Yakovleva T, Lafera J, Baumgärtner W, Krueger A, Prinz I, Gossler A, Kotlyarov A, Gaestel M.

Mol Cell Biol. 2019 Mar 1;39(6). pii: e00516-18. doi: 10.1128/MCB.00516-18. Print 2019 Mar 15.

PMID:
30642948
2.

The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.

Tveriakhina L, Schuster-Gossler K, Jarrett SM, Andrawes MB, Rohrbach M, Blacklow SC, Gossler A.

Elife. 2018 Oct 5;7. pii: e40045. doi: 10.7554/eLife.40045.

3.

The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice.

Beckers A, Ott T, Schuster-Gossler K, Boldt K, Alten L, Ueffing M, Blum M, Gossler A.

Sci Rep. 2018 Oct 2;8(1):14678. doi: 10.1038/s41598-018-33045-2.

4.

A novel Cre-inducible knock-in ARL13B-tRFP fusion cilium reporter.

Schmitz F, Burtscher I, Stauber M, Gossler A, Lickert H.

Genesis. 2017 Nov;55(11). doi: 10.1002/dvg.23073. Epub 2017 Oct 13.

PMID:
28948682
5.

1700012B09Rik, a FOXJ1 effector gene active in ciliated tissues of the mouse but not essential for motile ciliogenesis.

Stauber M, Boldt K, Wrede C, Weidemann M, Kellner M, Schuster-Gossler K, Kühnel MP, Hegermann J, Ueffing M, Gossler A.

Dev Biol. 2017 Sep 1;429(1):186-199. doi: 10.1016/j.ydbio.2017.06.027. Epub 2017 Jun 28.

6.

CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.

Weidemann M, Schuster-Gossler K, Stauber M, Wrede C, Hegermann J, Ott T, Boldt K, Beyer T, Serth K, Kremmer E, Blum M, Ueffing M, Gossler A.

Development. 2016 Dec 15;143(24):4736-4748.

7.

Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.

Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A.

Dev Biol. 2017 Mar 15;423(2):170-188. doi: 10.1016/j.ydbio.2016.11.019. Epub 2016 Dec 1.

8.

Effects of varenicline on sympatho-vagal balance and cue reactivity during smoking withdrawal: a randomised placebo-controlled trial.

Haarmann H, Gossler A, Herrmann P, Bonev S, Nguyen XP, Hasenfuß G, Andreas S, Raupach T.

Tob Induc Dis. 2016 Aug 8;14:26. doi: 10.1186/s12971-016-0091-x. eCollection 2016.

9.

A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas.

Zender S, Nickeleit I, Wuestefeld T, Sörensen I, Dauch D, Bozko P, El-Khatib M, Geffers R, Bektas H, Manns MP, Gossler A, Wilkens L, Plentz R, Zender L, Malek NP.

Cancer Cell. 2016 Aug 8;30(2):353-356. doi: 10.1016/j.ccell.2016.07.005. Epub 2016 Aug 8. No abstract available.

10.

Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.

Schuster-Gossler K, Cordes R, Müller J, Geffers I, Delany-Heiken P, Taft M, Preller M, Gossler A.

Genetics. 2016 Mar;202(3):1119-33. doi: 10.1534/genetics.115.184515. Epub 2016 Jan 22.

11.

Generation of an 870 kb deletion encompassing the Skt/Etl4 locus by combination of inter- and intra-chromosomal recombination.

Serth K, Beckers A, Schuster-Gossler K, Pavlova MN, Müller J, Paul MC, Reinhardt R, Gossler A.

BMC Genet. 2015 Dec 18;16:143. doi: 10.1186/s12863-015-0302-0.

12.

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo.

Preuße K, Tveriakhina L, Schuster-Gossler K, Gaspar C, Rosa AI, Henrique D, Gossler A, Stauber M.

PLoS Genet. 2015 Jun 26;11(6):e1005328. doi: 10.1371/journal.pgen.1005328. eCollection 2015 Jun.

13.

O-fucosylation of DLL3 is required for its function during somitogenesis.

Serth K, Schuster-Gossler K, Kremmer E, Hansen B, Marohn-Köhn B, Gossler A.

PLoS One. 2015 Apr 9;10(4):e0123776. doi: 10.1371/journal.pone.0123776. eCollection 2015.

14.

Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis.

Menon MB, Sawada A, Chaturvedi A, Mishra P, Schuster-Gossler K, Galla M, Schambach A, Gossler A, Förster R, Heuser M, Kotlyarov A, Kinoshita M, Gaestel M.

PLoS Genet. 2014 Aug 14;10(8):e1004558. doi: 10.1371/journal.pgen.1004558. eCollection 2014 Aug.

15.

Physiological effects of cigarette smoking in the limbic system revealed by 3 tesla magnetic resonance spectroscopy.

Mennecke A, Gossler A, Hammen T, Dörfler A, Stadlbauer A, Rösch J, Kornhuber J, Bleich S, Dölken M, Thürauf N.

J Neural Transm (Vienna). 2014 Oct;121(10):1211-9. doi: 10.1007/s00702-014-1190-6. Epub 2014 Mar 19.

PMID:
24643301
16.

O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function.

Müller J, Rana NA, Serth K, Kakuda S, Haltiwanger RS, Gossler A.

PLoS One. 2014 Feb 12;9(2):e88571. doi: 10.1371/journal.pone.0088571. eCollection 2014.

17.

S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development.

Braune EB, Schuster-Gossler K, Lyszkiewicz M, Serth K, Preusse K, Madlung J, Macek B, Krueger A, Gossler A.

Mol Cell Biol. 2014 Apr;34(7):1221-33. doi: 10.1128/MCB.00965-13. Epub 2014 Jan 21.

18.

Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo.

Redeker C, Schuster-Gossler K, Kremmer E, Gossler A.

PLoS One. 2013 Oct 22;8(10):e79050. doi: 10.1371/journal.pone.0079050. eCollection 2013.

19.

A critical role for notch signaling in the formation of cholangiocellular carcinomas.

Zender S, Nickeleit I, Wuestefeld T, Sörensen I, Dauch D, Bozko P, El-Khatib M, Geffers R, Bektas H, Manns MP, Gossler A, Wilkens L, Plentz R, Zender L, Malek NP.

Cancer Cell. 2013 Jun 10;23(6):784-95. doi: 10.1016/j.ccr.2013.04.019. Epub 2013 May 30. Erratum in: Cancer Cell. 2016 Aug 8;30(2):353-356.

20.

A novel mammal-specific three partite enhancer element regulates node and notochord-specific Noto expression.

Alten L, Schuster-Gossler K, Eichenlaub MP, Wittbrodt B, Wittbrodt J, Gossler A.

PLoS One. 2012;7(10):e47785. doi: 10.1371/journal.pone.0047785. Epub 2012 Oct 22.

21.

Olfactory perception in schizophrenia: the rating range for hedonic judgements is increased during acute episodes.

Clepce M, Reich K, Gossler A, Kornhuber J, Thuerauf N.

Psychiatry Res. 2013 Jun 30;208(1):81-3. doi: 10.1016/j.psychres.2012.09.052. Epub 2012 Oct 22.

PMID:
23089162
22.

Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.

Alten L, Schuster-Gossler K, Beckers A, Groos S, Ulmer B, Hegermann J, Ochs M, Gossler A.

Development. 2012 Apr;139(7):1276-84. doi: 10.1242/dev.072728. Epub 2012 Feb 22.

23.

Olfactory abnormalities in anxiety disorders.

Clepce M, Reich K, Gossler A, Kornhuber J, Thuerauf N.

Neurosci Lett. 2012 Mar 5;511(1):43-6. doi: 10.1016/j.neulet.2012.01.034. Epub 2012 Jan 24.

PMID:
22306090
24.

Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies.

Hoch M, Fischer P, Stapel B, Missol-Kolka E, Sekkali B, Scherr M, Favret F, Braun T, Eder M, Schuster-Gossler K, Gossler A, Hilfiker A, Balligand JL, Drexler H, Hilfiker-Kleiner D.

Cell Stem Cell. 2011 Aug 5;9(2):131-43. doi: 10.1016/j.stem.2011.07.001.

25.

α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice.

Girós A, Grgur K, Gossler A, Costell M.

PLoS One. 2011;6(7):e22002. doi: 10.1371/journal.pone.0022002. Epub 2011 Jul 22.

26.

ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior.

Lenz B, Klafki HW, Hillemacher T, Frieling H, Clepce M, Gossler A, Thuerauf N, Winterer G, Kornhuber J, Bleich S.

Addict Biol. 2012 Nov;17(6):1026-35. doi: 10.1111/j.1369-1600.2010.00264.x. Epub 2010 Nov 11.

PMID:
21070506
27.

The relation between depression, anhedonia and olfactory hedonic estimates--a pilot study in major depression.

Clepce M, Gossler A, Reich K, Kornhuber J, Thuerauf N.

Neurosci Lett. 2010 Mar 8;471(3):139-43. doi: 10.1016/j.neulet.2010.01.027. Epub 2010 Jan 25.

PMID:
20097263
28.

Smoking behaviour is associated with expression and phosphorylation of CREB in human buffy coat.

Lenz B, Klafki HW, Hillemacher T, Killisch N, Schaller G, Frieling H, Clepce M, Gossler A, Thuerauf N, Winterer G, Kornhuber J, Bleich S.

Int J Neuropsychopharmacol. 2010 Mar;13(2):207-15. doi: 10.1017/S1461145709991052. Epub 2010 Jan 5.

PMID:
20047710
29.

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE.

Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56. doi: 10.1152/ajplung.90550.2008. Epub 2009 Nov 6.

30.

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis.

Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M, Adams RH.

Cell. 2009 Jun 12;137(6):1124-35. doi: 10.1016/j.cell.2009.03.025.

31.

Emotional reactivity to odors: olfactory sensitivity and the span of emotional evaluation separate the genders.

Thuerauf N, Reulbach U, Lunkenheimer J, Lunkenheimer B, Spannenberger R, Gossler A, Maihöfner C, Bleich S, Kornhuber J, Markovic K.

Neurosci Lett. 2009 Jun 5;456(2):74-9. doi: 10.1016/j.neulet.2009.03.096. Epub 2009 Apr 2.

PMID:
19429137
32.

Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity.

Rocha SF, Lopes SS, Gossler A, Henrique D.

Dev Biol. 2009 Apr 1;328(1):54-65. doi: 10.1016/j.ydbio.2009.01.011. Epub 2009 Jan 14.

33.

Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development.

Schuster-Gossler K, Harris B, Johnson KR, Serth J, Gossler A.

BMC Dev Biol. 2009 Jan 22;9:6. doi: 10.1186/1471-213X-9-6.

34.

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries.

Sörensen I, Adams RH, Gossler A.

Blood. 2009 May 28;113(22):5680-8. doi: 10.1182/blood-2008-08-174508. Epub 2009 Jan 14.

35.

Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms.

Feyerabend TB, Terszowski G, Tietz A, Blum C, Luche H, Gossler A, Gale NW, Radtke F, Fehling HJ, Rodewald HR.

Immunity. 2009 Jan 16;30(1):67-79. doi: 10.1016/j.immuni.2008.10.016. Epub 2008 Dec 24.

36.

Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.

Feller J, Schneider A, Schuster-Gossler K, Gossler A.

Genes Dev. 2008 Aug 15;22(16):2166-71. doi: 10.1101/gad.480408.

37.

Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition.

Nickeleit I, Zender S, Sasse F, Geffers R, Brandes G, Sörensen I, Steinmetz H, Kubicka S, Carlomagno T, Menche D, Gütgemann I, Buer J, Gossler A, Manns MP, Kalesse M, Frank R, Malek NP.

Cancer Cell. 2008 Jul 8;14(1):23-35. doi: 10.1016/j.ccr.2008.05.016.

38.

Olfactory lateralization: odor intensity but not the hedonic estimation is lateralized.

Thuerauf N, Gossler A, Lunkenheimer J, Lunkenheimer B, Maihöfner C, Bleich S, Kornhuber J, Markovic K, Reulbach U.

Neurosci Lett. 2008 Jun 20;438(2):228-32. doi: 10.1016/j.neulet.2008.04.038. Epub 2008 May 9.

PMID:
18472214
39.

Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms.

Yamanaka Y, Tamplin OJ, Beckers A, Gossler A, Rossant J.

Dev Cell. 2007 Dec;13(6):884-96.

40.

Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis.

Estrach S, Cordes R, Hozumi K, Gossler A, Watt FM.

J Invest Dermatol. 2008 Apr;128(4):825-32. Epub 2007 Oct 25.

41.

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.

Beckers A, Alten L, Viebahn C, Andre P, Gossler A.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15765-70. Epub 2007 Sep 20. Erratum in: Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17554.

42.

Gastroesophageal reflux and behavior in neurologically impaired children.

Gössler A, Schalamon J, Huber-Zeyringer A, Höllwarth ME.

J Pediatr Surg. 2007 Sep;42(9):1486-90.

PMID:
17848235
43.

Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6.

Wittler L, Shin EH, Grote P, Kispert A, Beckers A, Gossler A, Werber M, Herrmann BG.

EMBO Rep. 2007 Aug;8(8):784-9. Epub 2007 Jul 13.

44.

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.

Geffers I, Serth K, Chapman G, Jaekel R, Schuster-Gossler K, Cordes R, Sparrow DB, Kremmer E, Dunwoodie SL, Klein T, Gossler A.

J Cell Biol. 2007 Jul 30;178(3):465-76.

45.

Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints.

Teppner I, Becker S, de Angelis MH, Gossler A, Beckers J.

BMC Dev Biol. 2007 Jun 17;7:68.

46.

Notch ligand Delta-like 1 is essential for postnatal arteriogenesis.

Limbourg A, Ploom M, Elligsen D, Sörensen I, Ziegelhoeffer T, Gossler A, Drexler H, Limbourg FP.

Circ Res. 2007 Feb 16;100(3):363-71. Epub 2007 Jan 18.

PMID:
17234965
47.

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R.

Development. 2007 Feb;134(4):801-11. Epub 2007 Jan 17.

48.

Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

Schuster-Gossler K, Cordes R, Gossler A.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):537-42. Epub 2006 Dec 28.

49.

Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.

Castro DS, Skowronska-Krawczyk D, Armant O, Donaldson IJ, Parras C, Hunt C, Critchley JA, Nguyen L, Gossler A, Göttgens B, Matter JM, Guillemot F.

Dev Cell. 2006 Dec;11(6):831-44.

50.

Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons.

Ji SJ, Zhuang B, Falco C, Schneider A, Schuster-Gossler K, Gossler A, Sockanathan S.

Dev Biol. 2006 Sep 1;297(1):249-61. Epub 2006 May 19.

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