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Items: 1 to 50 of 53

1.

Supercritical carbon dioxide decellularised pericardium: Mechanical and structural characterisation for applications in cardio-thoracic surgery.

Halfwerk FR, Rouwkema J, Gossen JA, Grandjean JG.

J Mech Behav Biomed Mater. 2018 Jan;77:400-407. doi: 10.1016/j.jmbbm.2017.10.002. Epub 2017 Oct 3.

PMID:
29020662
2.

Ovary-specific depletion of the nuclear receptor Nr5a2 compromises expansion of the cumulus oophorus but not fertilization by intracytoplasmic sperm injection.

Bertolin K, Meinsohn MC, Suzuki J, Gossen J, Schoonjans K, Duggavathi R, Murphy BD.

Biol Reprod. 2017 Jun 1;96(6):1231-1243. doi: 10.1093/biolre/iox045.

PMID:
28520915
3.

Core Binding Factor-β Knockdown Alters Ovarian Gene Expression and Function in the Mouse.

Wilson K, Park J, Curry TE Jr, Mishra B, Gossen J, Taniuchi I, Jo M.

Mol Endocrinol. 2016 Jul;30(7):733-47. doi: 10.1210/me.2015-1312. Epub 2016 May 13.

4.

The orphan nuclear receptor Nr5a2 is essential for luteinization in the female mouse ovary.

Bertolin K, Gossen J, Schoonjans K, Murphy BD.

Endocrinology. 2014 May;155(5):1931-43. doi: 10.1210/en.2013-1765. Epub 2014 Feb 19.

PMID:
24552399
5.

Ovulation involves the luteinizing hormone-dependent activation of G(q/11) in granulosa cells.

Breen SM, Andric N, Ping T, Xie F, Offermans S, Gossen JA, Ascoli M.

Mol Endocrinol. 2013 Sep;27(9):1483-91. doi: 10.1210/me.2013-1130. Epub 2013 Jul 8.

6.

Reversible infertility in a liver receptor homologue-1 (LRH-1)-knockdown mouse model.

Gerrits H, Paradé MC, Koonen-Reemst AM, Bakker NE, Timmer-Hellings L, Sollewijn Gelpke MD, Gossen JA.

Reprod Fertil Dev. 2014 Jan;26(2):293-306. doi: 10.1071/RD12131.

PMID:
23425349
7.

FZD1 regulates cumulus expansion genes and is required for normal female fertility in mice.

Lapointe E, Boyer A, Rico C, Paquet M, Franco HL, Gossen J, DeMayo FJ, Richards JS, Boerboom D.

Biol Reprod. 2012 Nov 1;87(5):104. doi: 10.1095/biolreprod.112.102608. Print 2012 Nov.

8.

Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility.

Bennett J, Wu YG, Gossen J, Zhou P, Stocco C.

Endocrinology. 2012 May;153(5):2474-85. doi: 10.1210/en.2011-1969. Epub 2012 Mar 20.

9.

Inhibitors of cathepsin K: a patent review (2004 - 2010).

Wijkmans J, Gossen J.

Expert Opin Ther Pat. 2011 Oct;21(10):1611-29. doi: 10.1517/13543776.2011.616283. Review.

PMID:
21923554
10.

Gender-specific increase of bone mass by CART peptide treatment is ovary-dependent.

Gerrits H, Bakker NE, van de Ven-de Laat CJ, Bourgondien FG, Peddemors C, Litjens RH, Kok HJ, Vogel GM, Krajnc-Franken MA, Gossen JA.

J Bone Miner Res. 2011 Dec;26(12):2886-98. doi: 10.1002/jbmr.500.

11.

Lrp5 functions in bone to regulate bone mass.

Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, Robinson DR, Zhong Z, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Liu Q, Mseeh F, Powell DR, Yang QM, Zambrowicz B, Gerrits H, Gossen JA, He X, Bader M, Williams BO, Warman ML, Robling AG.

Nat Med. 2011 Jun;17(6):684-91. doi: 10.1038/nm.2388. Epub 2011 May 22.

12.

Functional transformation of the chromatoid body in mouse spermatids requires testis-specific serine/threonine kinases.

Shang P, Baarends WM, Hoogerbrugge J, Ooms MP, van Cappellen WA, de Jong AA, Dohle GR, van Eenennaam H, Gossen JA, Grootegoed JA.

J Cell Sci. 2010 Feb 1;123(Pt 3):331-9. doi: 10.1242/jcs.059949. Epub 2010 Jan 5.

13.

Relaxin family peptide receptor-1 protects against airway fibrosis during homeostasis but not against fibrosis associated with chronic allergic airways disease.

Samuel CS, Royce SG, Chen B, Cao H, Gossen JA, Tregear GW, Tang ML.

Endocrinology. 2009 Mar;150(3):1495-502. doi: 10.1210/en.2008-1062. Epub 2008 Oct 30.

PMID:
18974264
14.

Role for PADI6 and the cytoplasmic lattices in ribosomal storage in oocytes and translational control in the early mouse embryo.

Yurttas P, Vitale AM, Fitzhenry RJ, Cohen-Gould L, Wu W, Gossen JA, Coonrod SA.

Development. 2008 Aug;135(15):2627-36. doi: 10.1242/dev.016329. Epub 2008 Jul 3.

15.

Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation.

Fan HY, Shimada M, Liu Z, Cahill N, Noma N, Wu Y, Gossen J, Richards JS.

Development. 2008 Jun;135(12):2127-37. doi: 10.1242/dev.020560.

16.

Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice.

Gerrits H, van Ingen Schenau DS, Bakker NE, van Disseldorp AJ, Strik A, Hermens LS, Koenen TB, Krajnc-Franken MA, Gossen JA.

Genesis. 2008 May;46(5):235-45. doi: 10.1002/dvg.20387.

PMID:
18442043
17.

Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility.

Esposito G, Vitale AM, Leijten FP, Strik AM, Koonen-Reemst AM, Yurttas P, Robben TJ, Coonrod S, Gossen JA.

Mol Cell Endocrinol. 2007 Jul 15;273(1-2):25-31. Epub 2007 May 17.

PMID:
17587491
18.

The testis anion transporter 1 (Slc26a8) is required for sperm terminal differentiation and male fertility in the mouse.

Touré A, Lhuillier P, Gossen JA, Kuil CW, Lhôte D, Jégou B, Escalier D, Gacon G.

Hum Mol Genet. 2007 Aug 1;16(15):1783-93. Epub 2007 May 20.

PMID:
17517695
19.

Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis.

Kimmins S, Crosio C, Kotaja N, Hirayama J, Monaco L, Höög C, van Duin M, Gossen JA, Sassone-Corsi P.

Mol Endocrinol. 2007 Mar;21(3):726-39. Epub 2006 Dec 27.

PMID:
17192404
20.

Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.

Xie F, Garcia MA, Carlson AE, Schuh SM, Babcock DF, Jaiswal BS, Gossen JA, Esposito G, van Duin M, Conti M.

Dev Biol. 2006 Aug 15;296(2):353-62. Epub 2006 Jun 7.

21.

Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.

Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W.

Eur J Immunol. 2005 Sep;35(9):2573-82.

22.

Localization of LGR7 gene expression in adult mouse brain using LGR7 knock-out/LacZ knock-in mice: correlation with LGR7 mRNA distribution.

Piccenna L, Shen PJ, Ma S, Burazin TC, Gossen JA, Mosselman S, Bathgate RA, Gundlach AL.

Ann N Y Acad Sci. 2005 May;1041:197-204.

PMID:
15956708
23.

Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development.

Gu P, Goodwin B, Chung AC, Xu X, Wheeler DA, Price RR, Galardi C, Peng L, Latour AM, Koller BH, Gossen J, Kliewer SA, Cooney AJ.

Mol Cell Biol. 2005 May;25(9):3492-505.

24.

Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect.

Esposito G, Jaiswal BS, Xie F, Krajnc-Franken MA, Robben TJ, Strik AM, Kuil C, Philipsen RL, van Duin M, Conti M, Gossen JA.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2993-8. Epub 2004 Feb 19. Erratum in: Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5180. Jaiswal Byjay S [corrected to Jaiswal Bijay S].

25.

Impaired nipple development and parturition in LGR7 knockout mice.

Krajnc-Franken MA, van Disseldorp AJ, Koenders JE, Mosselman S, van Duin M, Gossen JA.

Mol Cell Biol. 2004 Jan;24(2):687-96.

26.

Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine.

Dollé ME, Snyder WK, Gossen JA, Lohman PH, Vijg J.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8403-8.

27.

Quantitative correlation between radiation-induced mutagenesis in endogenous genes and transgenes of mouse spermatogonial stem cells.

Martus HJ, Novak M, Blecher D, van Duyn-Goedhart A, Suter W, Gossen JA, van Buul PP.

Environ Mol Mutagen. 1999;34(2-3):216-20.

PMID:
10529747
28.

Temporal and molecular characteristics of lacZ mutations in somatic tissues of transgenic mice.

Douglas GR, Jiao J, Gingerich JD, Soper LM, Gossen JA.

Environ Mol Mutagen. 1996;28(4):317-24.

PMID:
8991059
29.

Evaluation of a plasmid-based transgenic mouse model for detecting in vivo mutations.

Dollé ME, Martus HJ, Gossen JA, Boerrigter ME, Vijg J.

Mutagenesis. 1996 Jan;11(1):111-8.

PMID:
8671725
30.

Plasmid-based transgenic mouse model for studying in vivo mutations.

Boerrigter ME, Dollé ME, Martus HJ, Gossen JA, Vijg J.

Nature. 1995 Oct 19;377(6550):657-9. Review.

PMID:
7566182
31.

Use of transgenic mouse models for studying somatic mutations in aging.

Martus HJ, Dollé ME, Gossen JA, Boerrigter ME, Vijg J.

Mutat Res. 1995 Oct;338(1-6):203-13. Review.

PMID:
7565876
32.

Spontaneous and X-ray-induced deletion mutations in a LacZ plasmid-based transgenic mouse model.

Gossen JA, Martus HJ, Wei JY, Vijg J.

Mutat Res. 1995 Sep;331(1):89-97.

PMID:
7666872
33.
34.

Sequence spectra of spontaneous lacZ gene mutations in transgenic mouse somatic and germline tissues.

Douglas GR, Gingerich JD, Gossen JA, Bartlett SA.

Mutagenesis. 1994 Sep;9(5):451-8.

PMID:
7837979
35.

LacZ transgenic mouse models: their application in genetic toxicology.

Gossen JA, de Leeuw WJ, Vijg J.

Mutat Res. 1994 Jun 1;307(2):451-9. Review.

PMID:
7514719
36.

DNA sequence analysis of spontaneous mutations at a LacZ transgene integrated on the mouse X chromosome.

Gossen JA, de Leeuw WJ, Bakker AQ, Vijg J.

Mutagenesis. 1993 May;8(3):243-7.

PMID:
8332087
37.

Plasmid rescue from transgenic mouse DNA using LacI repressor protein conjugated to magnetic beads.

Gossen JA, de Leeuw WJ, Molijn AC, Vijg J.

Biotechniques. 1993 Apr;14(4):624-9.

PMID:
8476606
38.

Somatic mutations and cellular aging.

Vijg J, Gossen JA.

Comp Biochem Physiol B. 1993 Mar;104(3):429-37. Review. No abstract available.

PMID:
8482073
39.

A selective system for lacZ- phage using a galactose-sensitive E. coli host.

Gossen JA, Vijg J.

Biotechniques. 1993 Mar;14(3):326, 330. No abstract available.

PMID:
8457332
40.

Detection of chemical mutagens using Muta Mouse: a transgenic mouse model.

Hoorn AJ, Custer LL, Myhr BC, Brusick D, Gossen J, Vijg J.

Mutagenesis. 1993 Jan;8(1):7-10.

PMID:
8450770
41.

Transgenic mice as model systems for studying gene mutations in vivo.

Gossen J, Vijg J.

Trends Genet. 1993 Jan;9(1):27-31. Review.

PMID:
8434414
42.

Transgenic mice and age-related mutations.

Vijg J, de Leeuw WJ, Douglas GR, Gossen JA.

Ann N Y Acad Sci. 1992 Nov 21;663:26-35. No abstract available.

PMID:
1482058
43.

Contributions from molecular/biochemical approaches in epidemiology to cancer risk assessment and prevention.

Lohman PH, Morolli B, Darroudi F, Natarajan AT, Gossen JA, Venema J, Mullenders LH, Vogel EW, Vrieling H, van Zeeland AA.

Environ Health Perspect. 1992 Nov;98:155-65. No abstract available.

44.

Application of galactose-sensitive E. coli strains as selective hosts for LacZ- plasmids.

Gossen JA, Molijn AC, Douglas GR, Vijg J.

Nucleic Acids Res. 1992 Jun 25;20(12):3254. No abstract available.

45.

Detection of migrated allogeneic oligodendrocytes throughout the central nervous system of the galactocerebrosidase-deficient twitcher mouse.

Huppes W, De Groot CJ, Ostendorf RH, Bauman JG, Gossen JA, Smit V, Vijg J, Dijkstra CD.

J Neurocytol. 1992 Feb;21(2):129-36.

PMID:
1348528
46.

High somatic mutation frequencies in a LacZ transgene integrated on the mouse X-chromosome.

Gossen JA, de Leeuw WJ, Verwest A, Lohman PH, Vijg J.

Mutat Res. 1991 Sep-Oct;250(1-2):423-9.

PMID:
1944355
47.

DNA processing, aging, and cancer. The impact of new technology.

Vijg J, Gossen JA, De Leeuw WJ, Mullaart E, Slagboom PE, Uitterlinden AG.

Ann N Y Acad Sci. 1991;621:53-65. Review. No abstract available.

PMID:
1859102
48.

Analysis of spontaneous and induced mutation frequencies in transgenic mice using a lambda shuttle vector system.

Gossen JA, de Leeuw WJ, Verwest M, Vijg J.

Prog Clin Biol Res. 1991;372:313-8. No abstract available.

PMID:
1835538
49.

Transgenic mouse--an in vivo system for detection of aneugens.

Natarajan AT, Vlasblom SE, Manca A, Lohman PH, Gossen JA, Vijg J, Beermann F, Hummler E, Hansmann I.

Prog Clin Biol Res. 1990;340B:295-9. No abstract available.

PMID:
2392447
50.

Transgenic mice as a model to study gene mutations: application as a short-term mutagenicity assay.

Gossen JA, Vijg J.

Prog Clin Biol Res. 1990;340A:347-54. No abstract available.

PMID:
2388919

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