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Behavioural responses of the hagfish Eptatretus stoutii to nutrient and noxious stimuli.

Glover CN, Newton D, Bajwa J, Goss GG, Hamilton TJ.

Sci Rep. 2019 Sep 16;9(1):13369. doi: 10.1038/s41598-019-49863-x.


The Effect of Major Ions and Dissolved Organic Matter on Complexation and Toxicity of Dissolved Thallium to Daphnia magna.

Nagel AH, Cuss CW, Goss GG, Shotyk W, Glover CN.

Environ Toxicol Chem. 2019 Aug 6. doi: 10.1002/etc.4557. [Epub ahead of print]


Ventilatory sensitivity to ammonia in the Pacific hagfish (Eptatretus stoutii), a representative of the oldest extant connection to the ancestral vertebrates.

Eom J, Giacomin M, Clifford AM, Goss GG, Wood CM.

J Exp Biol. 2019 Jul 19;222(Pt 14). pii: jeb199794. doi: 10.1242/jeb.199794.


Selumetinib in patients receiving standard pemetrexed and platinum-based chemotherapy for advanced or metastatic KRAS wildtype or unknown non-squamous non-small cell lung cancer: A randomized, multicenter, phase II study. Canadian Cancer Trials Group (CCTG) IND.219.

Melosky B, Bradbury P, Tu D, Florescu M, Reiman A, Nicholas G, Basappa N, Rothenstein J, Goffin JR, Laurie SA, Wheatley-Price P, Leighl N, Goss G, Reaume MN, Butts C, Murray N, Card C, Ko J, Blais N, Gray S, Lui H, Brown-Walker P, Kaurah P, Prentice LM, Seymour L.

Lung Cancer. 2019 Jul;133:48-55. doi: 10.1016/j.lungcan.2019.04.027. Epub 2019 May 1.


Cell-Based Therapy Restores Olfactory Function in an Inducible Model of Hyposmia.

Kurtenbach S, Goss GM, Goncalves S, Choi R, Hare JM, Chaudhari N, Goldstein BJ.

Stem Cell Reports. 2019 Jun 11;12(6):1354-1365. doi: 10.1016/j.stemcr.2019.05.001. Epub 2019 May 30.


Arthrographic Study of the Communication between the Tarsal Joints in Crioulo Horses.

Gehm MV, Duarte CA, Leite CT, Góss GC, Döwich G, Pereira EP, da Rosa LR, Romero BG.

Vet Comp Orthop Traumatol. 2019 Jul;32(4):269-273. doi: 10.1055/s-0039-1688770. Epub 2019 May 28.


Toxicity in aquatic model species exposed to a temporal series of three different flowback and produced water samples collected from a horizontal hydraulically fractured well.

Folkerts EJ, Blewett TA, Delompré P, Mehler WT, Flynn SL, Sun C, Zhang Y, Martin JW, Alessi DS, Goss GG.

Ecotoxicol Environ Saf. 2019 Sep 30;180:600-609. doi: 10.1016/j.ecoenv.2019.05.054. Epub 2019 May 24.


Safety, Efficacy, and Patient-Reported Health-Related Quality of Life and Symptom Burden with Nivolumab in Patients with Advanced Non-Small Cell Lung Cancer, Including Patients Aged 70 Years or Older or with Poor Performance Status (CheckMate 153).

Spigel DR, McCleod M, Jotte RM, Einhorn L, Horn L, Waterhouse DM, Creelan B, Babu S, Leighl NB, Chandler JC, Couture F, Keogh G, Goss G, Daniel DB, Garon EB, Schwartzberg LS, Sen R, Korytowsky B, Li A, Aanur N, Hussein MA.

J Thorac Oncol. 2019 Sep;14(9):1628-1639. doi: 10.1016/j.jtho.2019.05.010. Epub 2019 May 20.


Global implications of regional grain production through virtual water trade.

Masud MB, Wada Y, Goss G, Faramarzi M.

Sci Total Environ. 2019 Apr 1;659:807-820. doi: 10.1016/j.scitotenv.2018.12.392. Epub 2018 Dec 28.


Activity and post-prandial regulation of digestive enzyme activity along the Pacific hagfish (Eptatretus stoutii) alimentary canal.

Weinrauch AM, Schaefer CM, Goss GG.

PLoS One. 2019 Apr 5;14(4):e0215027. doi: 10.1371/journal.pone.0215027. eCollection 2019.


Inpatients versus outpatients with advanced non-small cell lung cancer: Characteristics and outcomes.

Gotfrit J, Jonker C, Zhang T, Goss G, Nicholas G, Laurie S, Wheatley-Price P.

Cancer Treat Res Commun. 2019;19:100130. doi: 10.1016/j.ctarc.2019.100130. Epub 2019 Mar 23.


The osmotic effect of hyper-saline hydraulic fracturing fluid on rainbow trout, Oncorhynchus mykiss.

Delompré PLM, Blewett TA, Snihur KN, Flynn SL, Alessi DS, Glover CN, Goss GG.

Aquat Toxicol. 2019 Jun;211:1-10. doi: 10.1016/j.aquatox.2019.03.009. Epub 2019 Mar 14.


Mutant Lef1 controls Gata6 in sebaceous gland development and cancer.

Oulès B, Rognoni E, Hoste E, Goss G, Fiehler R, Natsuga K, Quist S, Mentink R, Donati G, Watt FM.

EMBO J. 2019 May 2;38(9). pii: e100526. doi: 10.15252/embj.2018100526. Epub 2019 Mar 18.


Shedding light on the effects of hydraulic fracturing flowback and produced water on phototactic behavior in Daphnia magna.

Delompré PLM, Blewett TA, Goss GG, Glover CN.

Ecotoxicol Environ Saf. 2019 Jun 15;174:315-323. doi: 10.1016/j.ecoenv.2019.03.006. Epub 2019 Mar 5.



Wallmann HW, Bell DL, Evans BL, Hyman AA, Goss GK, Paicely AM.

Int J Sports Phys Ther. 2019 Feb;14(1):55-64.


Health-related quality of life and anxiety in the PAN-CAN lung cancer screening cohort.

Taghizadeh N, Tremblay A, Cressman S, Peacock S, McWilliams AM, MacEachern P, Johnston MR, Goffin J, Goss G, Nicholas G, Martel S, Laberge F, Bhatia R, Liu G, Schmidt H, Atkar-Khattra S, Tsao MS, Tammemagi MC, Lam SC; Pan-Canadian Early Lung Cancer Study Group.

BMJ Open. 2019 Jan 17;9(1):e024719. doi: 10.1136/bmjopen-2018-024719.


Assessment of impacts of diphenyl phosphate on groundwater and near-surface environments: Sorption and toxicity.

Funk SP, Duffin L, He Y, McMullen C, Sun C, Utting N, Martin JW, Goss GG, Alessi DS.

J Contam Hydrol. 2019 Feb;221:50-57. doi: 10.1016/j.jconhyd.2019.01.002. Epub 2019 Jan 7.


Characterization and implications of solids associated with hydraulic fracturing flowback and produced water from the Duvernay Formation, Alberta, Canada.

Flynn SL, von Gunten K, Warchola T, Snihur K, Forbes TZ, Goss GG, Gingras MK, Konhauser KO, Alessi DS.

Environ Sci Process Impacts. 2019 Feb 21;21(2):242-255. doi: 10.1039/c8em00404h.


Osimertinib in patients with T790M mutation-positive, advanced non-small cell lung cancer: Long-term follow-up from a pooled analysis of 2 phase 2 studies.

Ahn MJ, Tsai CM, Shepherd FA, Bazhenova L, Sequist LV, Hida T, Yang JCH, Ramalingam SS, Mitsudomi T, Jänne PA, Mann H, Cantarini M, Goss G.

Cancer. 2019 Mar 15;125(6):892-901. doi: 10.1002/cncr.31891. Epub 2018 Dec 4.


Apixaban to Prevent Venous Thromboembolism in Patients with Cancer.

Carrier M, Abou-Nassar K, Mallick R, Tagalakis V, Shivakumar S, Schattner A, Kuruvilla P, Hill D, Spadafora S, Marquis K, Trinkaus M, Tomiak A, Lee AYY, Gross PL, Lazo-Langner A, El-Maraghi R, Goss G, Le Gal G, Stewart D, Ramsay T, Rodger M, Witham D, Wells PS; AVERT Investigators.

N Engl J Med. 2019 Feb 21;380(8):711-719. doi: 10.1056/NEJMoa1814468. Epub 2018 Dec 4.


Lipid acquisition and tissue storage in hagfish: new insights from an ancient vertebrate.

Weinrauch AM, Glover CN, Goss GG.

J Comp Physiol B. 2019 Feb;189(1):37-45. doi: 10.1007/s00360-018-1196-8. Epub 2018 Nov 28.


Multiple polycomb epigenetic regulatory proteins are active in normal and regenerating adult olfactory epithelium.

Goldstein BJ, Choi R, Goss GM.

Laryngoscope Investig Otolaryngol. 2018 Sep 17;3(5):337-344. doi: 10.1002/lio2.180. eCollection 2018 Oct.


In vitro assessment of endocrine disrupting potential of organic fractions extracted from hydraulic fracturing flowback and produced water (HF-FPW).

He Y, Zhang Y, Martin JW, Alessi DS, Giesy JP, Goss GG.

Environ Int. 2018 Dec;121(Pt 1):824-831. doi: 10.1016/j.envint.2018.10.014. Epub 2018 Oct 17.


Canadian Cancer Trials Group (CCTG) IND215: A phase Ib study of Selumetinib in patients with untreated advanced or metastatic NSCLC who are receiving standard chemotherapy regimens.

Goffin JR, Nicholas G, Mates M, Tu D, Chen E, Laurie SA, Juergens R, Robinson A, Goss G, Reaume M, Sun S, Christink K, Maize C, MacFarlan S, Sun X, Ritter H, Seymour L, Bradbury PA.

Invest New Drugs. 2019 Jun;37(3):498-506. doi: 10.1007/s10637-018-0680-z. Epub 2018 Oct 13.


Are clinical trial eligibility criteria an accurate reflection of a real-world population of advanced non-small-cell lung cancer patients?

Al-Baimani K, Jonker H, Zhang T, Goss GD, Laurie SA, Nicholas G, Wheatley-Price P.

Curr Oncol. 2018 Aug;25(4):e291-e297. doi: 10.3747/co.25.3978. Epub 2018 Aug 14.


Assessing the role of the acid-sensing ion channel ASIC4b in sodium uptake by larval zebrafish.

Zimmer AM, Dymowska AK, Kumai Y, Goss GG, Perry SF, Kwong RWM.

Comp Biochem Physiol A Mol Integr Physiol. 2018 Dec;226:1-10. doi: 10.1016/j.cbpa.2018.06.012. Epub 2018 Jun 15.


Association of ERBB Mutations With Clinical Outcomes of Afatinib- or Erlotinib-Treated Patients With Lung Squamous Cell Carcinoma: Secondary Analysis of the LUX-Lung 8 Randomized Clinical Trial.

Goss GD, Felip E, Cobo M, Lu S, Syrigos K, Lee KH, Göker E, Georgoulias V, Li W, Guclu S, Isla D, Min YJ, Morabito A, Ardizzoni A, Gadgeel SM, Fülöp A, Bühnemann C, Gibson N, Krämer N, Solca F, Cseh A, Ehrnrooth E, Soria JC.

JAMA Oncol. 2018 Sep 1;4(9):1189-1197. doi: 10.1001/jamaoncol.2018.0775.


Environmental and Human Health Impacts of Spreading Oil and Gas Wastewater on Roads.

Tasker TL, Burgos WD, Piotrowski P, Castillo-Meza L, Blewett TA, Ganow KB, Stallworth A, Delompré PLM, Goss GG, Fowler LB, Vanden Heuvel JP, Dorman F, Warner NR.

Environ Sci Technol. 2018 Jun 19;52(12):7081-7091. doi: 10.1021/acs.est.8b00716. Epub 2018 May 30.


Canadian Cancer Trials Group (CCTG) IND211: A randomized trial of pelareorep (Reolysin) in patients with previously treated advanced or metastatic non-small cell lung cancer receiving standard salvage therapy.

Bradbury PA, Morris DG, Nicholas G, Tu D, Tehfe M, Goffin JR, Shepherd FA, Gregg RW, Rothenstein J, Lee C, Kuruvilla S, Keith BD, Torri V, Blais N, Hao D, Korpanty GJ, Goss G, Melosky BL, Mates M, Leighl N, Ayoub JP, Sederias J, Feilotter H, Seymour L, Laurie SA.

Lung Cancer. 2018 Jun;120:142-148. doi: 10.1016/j.lungcan.2018.03.005. Epub 2018 Mar 9.


Physical immobility as a sensitive indicator of hydraulic fracturing fluid toxicity towards Daphnia magna.

Blewett TA, Delompré PLM, Glover CN, Goss GG.

Sci Total Environ. 2018 Sep 1;635:639-643. doi: 10.1016/j.scitotenv.2018.04.165. Epub 2018 Apr 24.


Update on International Cooperative Groups Studies in Thoracic Malignancies: The Emergence of Immunotherapy.

Shukla ND, Salahudeen AA, Taylor GA, Ramalingam SS, Vokes EE, Goss GD, Decker RH, Kelly K, Scagliotti GV, Mok TS, Wakelee HA.

Clin Lung Cancer. 2018 Sep;19(5):377-386. doi: 10.1016/j.cllc.2018.03.004. Epub 2018 Mar 17. Review.


Efficacy and safety results of depatuxizumab mafodotin (ABT-414) in patients with advanced solid tumors likely to overexpress epidermal growth factor receptor.

Goss GD, Vokes EE, Gordon MS, Gandhi L, Papadopoulos KP, Rasco DW, Fischer JS, Chu KL, Ames WW, Mittapalli RK, Lee HJ, Zeng J, Roberts-Rapp LA, Loberg LI, Ansell PJ, Reilly EB, Ocampo CJ, Holen KD, Tolcher AW.

Cancer. 2018 May 15;124(10):2174-2183. doi: 10.1002/cncr.31304. Epub 2018 Mar 13.


Developmental Toxicity of the Organic Fraction from Hydraulic Fracturing Flowback and Produced Waters to Early Life Stages of Zebrafish ( Danio rerio).

He Y, Sun C, Zhang Y, Folkerts EJ, Martin JW, Goss GG.

Environ Sci Technol. 2018 Mar 20;52(6):3820-3830. doi: 10.1021/acs.est.7b06557. Epub 2018 Feb 8.


CNS response to osimertinib in patients with T790M-positive advanced NSCLC: pooled data from two phase II trials.

Goss G, Tsai CM, Shepherd FA, Ahn MJ, Bazhenova L, Crinò L, de Marinis F, Felip E, Morabito A, Hodge R, Cantarini M, Johnson M, Mitsudomi T, Jänne PA, Yang JC.

Ann Oncol. 2018 Mar 1;29(3):687-693. doi: 10.1093/annonc/mdx820.


Dropping the base: recovery from extreme hypercarbia in the CO2 tolerant Pacific hagfish (Eptatretus stoutii).

Clifford AM, Weinrauch AM, Goss GG.

J Comp Physiol B. 2018 May;188(3):421-435. doi: 10.1007/s00360-017-1141-2. Epub 2017 Dec 30.


A novel pathway of nutrient absorption in crustaceans: branchial amino acid uptake in the green shore crab (Carcinus maenas).

Blewett TA, Goss GG.

Proc Biol Sci. 2017 Dec 6;284(1868). pii: 20171298. doi: 10.1098/rspb.2017.1298.


Functional redundancy of glucose acquisition mechanisms in the hindgut of Pacific hagfish (Eptatretus stoutii).

Weinrauch AM, Clifford AM, Goss GG.

Comp Biochem Physiol A Mol Integr Physiol. 2018 Feb;216:8-13. doi: 10.1016/j.cbpa.2017.10.034. Epub 2017 Nov 7.


Differential expression of microRNAs among cell populations in the regenerating adult mouse olfactory epithelium.

Kurtenbach S, Ding W, Goss GM, Hare JM, Goldstein BJ, Shehadeh LA.

PLoS One. 2017 Nov 6;12(11):e0187576. doi: 10.1371/journal.pone.0187576. eCollection 2017.


Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study.

Tammemagi MC, Schmidt H, Martel S, McWilliams A, Goffin JR, Johnston MR, Nicholas G, Tremblay A, Bhatia R, Liu G, Soghrati K, Yasufuku K, Hwang DM, Laberge F, Gingras M, Pasian S, Couture C, Mayo JR, Nasute Fauerbach PV, Atkar-Khattra S, Peacock SJ, Cressman S, Ionescu D, English JC, Finley RJ, Yee J, Puksa S, Stewart L, Tsai S, Haider E, Boylan C, Cutz JC, Manos D, Xu Z, Goss GD, Seely JM, Amjadi K, Sekhon HS, Burrowes P, MacEachern P, Urbanski S, Sin DD, Tan WC, Leighl NB, Shepherd FA, Evans WK, Tsao MS, Lam S; PanCan Study Team.

Lancet Oncol. 2017 Nov;18(11):1523-1531. doi: 10.1016/S1470-2045(17)30597-1. Epub 2017 Oct 18.


A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196.

Leighl NB, Tsao MS, Liu G, Tu D, Ho C, Shepherd FA, Murray N, Goffin JR, Nicholas G, Sakashita S, Chen Z, Kim L, Powers J, Seymour L, Goss G, Bradbury PA.

Oncotarget. 2017 Jun 28;8(41):69651-69662. doi: 10.18632/oncotarget.18753. eCollection 2017 Sep 19.


Alterations to Juvenile Zebrafish (Danio rerio) Swim Performance after Acute Embryonic Exposure to Sub-lethal Exposures of Hydraulic Fracturing Flowback and Produced Water.

Folkerts EJ, Blewett TA, He Y, Goss GG.

Aquat Toxicol. 2017 Dec;193:50-59. doi: 10.1016/j.aquatox.2017.10.003. Epub 2017 Oct 7.


Cadmium bioaccumulates after acute exposure but has no effect on locomotion or shelter-seeking behaviour in the invasive green shore crab (Carcinus maenas).

Blewett TA, Newton D, Flynn SL, Alessi DS, Goss GG, Hamilton TJ.

Conserv Physiol. 2017 Sep 28;5(1):cox057. doi: 10.1093/conphys/cox057. eCollection 2017.


Cardio-respirometry disruption in zebrafish (Danio rerio) embryos exposed to hydraulic fracturing flowback and produced water.

Folkerts EJ, Blewett TA, He Y, Goss GG.

Environ Pollut. 2017 Dec;231(Pt 2):1477-1487. doi: 10.1016/j.envpol.2017.09.011. Epub 2017 Sep 18.


Cellular uptake and intracellular localization of poly (acrylic acid) nanoparticles in a rainbow trout (Oncorhynchus mykiss) gill epithelial cell line, RTgill-W1.

Felix LC, Ortega VA, Goss GG.

Aquat Toxicol. 2017 Nov;192:58-68. doi: 10.1016/j.aquatox.2017.09.008. Epub 2017 Sep 7.


Symptom and Quality of Life Improvement in LUX-Lung 8, an Open-Label Phase III Study of Second-Line Afatinib Versus Erlotinib in Patients With Advanced Squamous Cell Carcinoma of the Lung After First-Line Platinum-Based Chemotherapy.

Felip E, Hirsh V, Popat S, Cobo M, Fülöp A, Dayen C, Trigo JM, Gregg R, Waller CF, Soria JC, Goss GD, Gordon J, Wang B, Palmer M, Ehrnrooth E, Gadgeel SM.

Clin Lung Cancer. 2018 Jan;19(1):74-83.e11. doi: 10.1016/j.cllc.2017.06.002. Epub 2017 Jun 23.


Post-prandial physiology and intestinal morphology of the Pacific hagfish (Eptatretus stoutii).

Weinrauch AM, Clifford AM, Goss GG.

J Comp Physiol B. 2018 Jan;188(1):101-112. doi: 10.1007/s00360-017-1118-1. Epub 2017 Jul 18.


Ammonia-independent sodium uptake mediated by Na+ channels and NHEs in the freshwater ribbon leech Nephelopsis obscura.

Quijada-Rodriguez AR, Schultz AG, Wilson JM, He Y, Allen GJP, Goss GG, Weihrauch D.

J Exp Biol. 2017 Sep 15;220(Pt 18):3270-3279. doi: 10.1242/jeb.159459. Epub 2017 Jul 6.


Physiological and morphological investigation of Arctic grayling (Thymallus arcticus) gill filaments with high salinity exposure and recovery.

Blair SD, Matheson D, Goss GG.

Conserv Physiol. 2017 Jun 28;5(1):cox040. doi: 10.1093/conphys/cox040. eCollection 2017.


The Impact of Baseline Edmonton Symptom Assessment Scale Scores on Treatment and Survival in Patients With Advanced Non-small-cell Lung Cancer.

McGee SF, Zhang T, Jonker H, Laurie SA, Goss G, Nicholas G, Albaimani K, Wheatley-Price P.

Clin Lung Cancer. 2018 Jan;19(1):e91-e99. doi: 10.1016/j.cllc.2017.05.018. Epub 2017 Jun 8.


Evaluation of the VeriStrat® serum protein test in patients with advanced squamous cell carcinoma of the lung treated with second-line afatinib or erlotinib in the phase III LUX-Lung 8 study.

Gadgeel S, Goss G, Soria JC, Felip E, Georgoulias V, Lu S, Cobo M, Syrigos K, Lee KH, Göker E, Guclu SZ, Isla D, Morabito A, Dupuis N, Bühnemann C, Krämer N, Solca F, Ehrnrooth E, Ardizzoni A.

Lung Cancer. 2017 Jul;109:101-108. doi: 10.1016/j.lungcan.2017.05.010. Epub 2017 May 11.

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