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Items: 1 to 50 of 345

1.

Rolling Circle cDNA Synthesis Uncovers Circular RNA Splice Variants.

Das A, Rout PK, Gorospe M, Panda AC.

Int J Mol Sci. 2019 Aug 16;20(16). pii: E3988. doi: 10.3390/ijms20163988.

2.

HuR regulates phospholamban expression in isoproterenol-induced cardiac remodeling.

Hu H, Jiang M, Cao Y, Zhang Z, Jiang B, Tian F, Feng J, Dou Y, Gorospe M, Zheng M, Zheng L, Yang Z, Wang W.

Cardiovasc Res. 2019 Aug 2. pii: cvz205. doi: 10.1093/cvr/cvz205. [Epub ahead of print]

PMID:
31373621
3.

Transcriptome signature of cellular senescence.

Casella G, Munk R, Kim KM, Piao Y, De S, Abdelmohsen K, Gorospe M.

Nucleic Acids Res. 2019 Aug 22;47(14):7294-7305. doi: 10.1093/nar/gkz555.

4.

Correction: Polysome Fractionation to Analyze mRNA Distribution Profiles.

Panda AC, Martindale JL, Gorospe M.

Bio Protoc. 2019 Feb 5;9(3). pii: e3176. doi: 10.21769/BioProtoc.3176.

5.

mRNA methylation in cell senescence.

Casella G, Tsitsipatis D, Abdelmohsen K, Gorospe M.

Wiley Interdiscip Rev RNA. 2019 May 29:e1547. doi: 10.1002/wrna.1547. [Epub ahead of print] Review.

PMID:
31144457
6.

RNA-Binding Protein HuR Regulates Paneth Cell Function by Altering Membrane Localization of TLR2 via Post-transcriptional Control of CNPY3.

Xiao L, Li XX, Chung HK, Kalakonda S, Cai JZ, Cao S, Chen N, Liu Y, Rao JN, Wang HY, Gorospe M, Wang JY.

Gastroenterology. 2019 Sep;157(3):731-743. doi: 10.1053/j.gastro.2019.05.010. Epub 2019 May 17.

PMID:
31103627
7.

Long noncoding RNAs in intestinal epithelium homeostasis.

Xiao L, Gorospe M, Wang JY.

Am J Physiol Cell Physiol. 2019 Jul 1;317(1):C93-C100. doi: 10.1152/ajpcell.00092.2019. Epub 2019 May 1.

PMID:
31042423
8.

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model.

Zhang P, Kishimoto Y, Grammatikakis I, Gottimukkala K, Cutler RG, Zhang S, Abdelmohsen K, Bohr VA, Misra Sen J, Gorospe M, Mattson MP.

Nat Neurosci. 2019 May;22(5):719-728. doi: 10.1038/s41593-019-0372-9. Epub 2019 Apr 1.

9.

Loss of miR-451a enhances SPARC production during myogenesis.

Munk R, Martindale JL, Yang X, Yang JH, Grammatikakis I, Di Germanio C, Mitchell SJ, de Cabo R, Lehrmann E, Zhang Y, Becker KG, Raz V, Gorospe M, Abdelmohsen K, Panda AC.

PLoS One. 2019 Mar 29;14(3):e0214301. doi: 10.1371/journal.pone.0214301. eCollection 2019.

10.

NF90 regulation of immune factor expression in response to malaria antigens.

Idda ML, Lodde V, Galleri G, Martindale JL, Munk R, Abdelmohsen K, Cucca F, Gorospe M.

Cell Cycle. 2019 Mar - Apr;18(6-7):708-722. doi: 10.1080/15384101.2019.1580496. Epub 2019 Mar 8.

PMID:
30784348
11.

Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program.

Noh JH, Kim KM, Pandey PR, Noren Hooten N, Munk R, Kundu G, De S, Martindale JL, Yang X, Evans MK, Abdelmohsen K, Gorospe M.

Nucleic Acids Res. 2019 Mar 18;47(5):2472-2486. doi: 10.1093/nar/gkz082.

12.

RPAD (RNase R treatment, polyadenylation, and poly(A)+ RNA depletion) method to isolate highly pure circular RNA.

Pandey PR, Rout PK, Das A, Gorospe M, Panda AC.

Methods. 2019 Feb 15;155:41-48. doi: 10.1016/j.ymeth.2018.10.022. Epub 2018 Nov 2.

PMID:
30391514
13.

Intracellular RNA-tracking methods.

George L, Indig FE, Abdelmohsen K, Gorospe M.

Open Biol. 2018 Oct 3;8(10). pii: 180104. doi: 10.1098/rsob.180104. Review.

14.

Cooperative translational control of polymorphic BAFF by NF90 and miR-15a.

Idda ML, Lodde V, McClusky WG, Martindale JL, Yang X, Munk R, Steri M, Orrù V, Mulas A, Cucca F, Abdelmohsen K, Gorospe M.

Nucleic Acids Res. 2018 Dec 14;46(22):12040-12051. doi: 10.1093/nar/gky866.

15.

The coding potential of circRNAs.

Das A, Gorospe M, Panda AC.

Aging (Albany NY). 2018 Sep 13;10(9):2228-2229. doi: 10.18632/aging.101554. No abstract available.

16.

Multi-leveled suppression of p53 function by HuR IncRNPs.

Yang JH, Gorospe M.

Noncoding RNA Investig. 2018 Jan;2. pii: 2. doi: 10.21037/ncri.2018.01.01. Epub 2018 Jan 17. No abstract available.

17.

Identifying intronic circRNAs: progress and challenges.

Panda AC, Gorospe M.

Noncoding RNA Investig. 2018 Jun;2. pii: 34. doi: 10.21037/ncri.2018.05.06. Epub 2018 Jun 14. No abstract available.

18.

MIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs.

Sun Q, Tripathi V, Yoon JH, Singh DK, Hao Q, Min KW, Davila S, Zealy RW, Li XL, Polycarpou-Schwarz M, Lehrmann E, Zhang Y, Becker KG, Freier SM, Zhu Y, Diederichs S, Prasanth SG, Lal A, Gorospe M, Prasanth KV.

Nucleic Acids Res. 2018 Nov 2;46(19):10405-10416. doi: 10.1093/nar/gky696.

19.

GRSF1 suppresses cell senescence.

Noh JH, Kim KM, Idda ML, Martindale JL, Yang X, Abdelmohsen K, Gorospe M.

Aging (Albany NY). 2018 Aug 7;10(8):1856-1866. doi: 10.18632/aging.101516.

20.

The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4+ Th2 Differentiation.

Techasintana P, Ellis JS, Glascock J, Gubin MM, Ridenhour SE, Magee JD, Hart ML, Yao P, Zhou H, Whitney MS, Franklin CL, Martindale JL, Gorospe M, Davis WJ, Fox PL, Li X, Atasoy U.

Immunohorizons. 2017 Aug 1;1(6):109-123. doi: 10.4049/immunohorizons.1700017.

21.

AKTions by Cytoplasmic lncRNA CASC9 Promote Hepatocellular Carcinoma Survival.

Noh JH, Gorospe M.

Hepatology. 2018 Nov;68(5):1675-1677. doi: 10.1002/hep.30165. Epub 2018 Oct 11. No abstract available.

22.

Author Correction: HuR regulates telomerase activity through TERC methylation.

Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Gorospe M, Ju Z, Wang W.

Nat Commun. 2018 Jul 10;9(1):2721. doi: 10.1038/s41467-018-05213-5.

23.

SCAMP4 enhances the senescent cell secretome.

Kim KM, Noh JH, Bodogai M, Martindale JL, Pandey PR, Yang X, Biragyn A, Abdelmohsen K, Gorospe M.

Genes Dev. 2018 Jul 1;32(13-14):909-914. doi: 10.1101/gad.313270.118.

24.

HuR regulates telomerase activity through TERC methylation.

Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Gorospe M, Ju Z, Wang W.

Nat Commun. 2018 Jun 7;9(1):2213. doi: 10.1038/s41467-018-04617-7. Erratum in: Nat Commun. 2018 Jul 10;9(1):2721.

25.

Detection and Analysis of Circular RNAs by RT-PCR.

Panda AC, Gorospe M.

Bio Protoc. 2018 Mar 20;8(6). pii: e2775. doi: 10.21769/BioProtoc.2775.

26.

Regulation of Intestinal Epithelial Barrier Function by Long Noncoding RNA uc.173 through Interaction with MicroRNA 29b.

Wang JY, Cui YH, Xiao L, Chung HK, Zhang Y, Rao JN, Gorospe M, Wang JY.

Mol Cell Biol. 2018 Jun 14;38(13). pii: e00010-18. doi: 10.1128/MCB.00010-18. Print 2018 Jul 1.

27.

Stress granules counteract senescence by sequestration of PAI-1.

Omer A, Patel D, Lian XJ, Sadek J, Di Marco S, Pause A, Gorospe M, Gallouzi IE.

EMBO Rep. 2018 May;19(5). pii: e44722. doi: 10.15252/embr.201744722. Epub 2018 Mar 28.

28.

A RAS-CaMKKβ-AMPKα2 pathway promotes senescence by licensing post-translational activation of C/EBPβ through a novel 3'UTR mechanism.

Basu SK, Gonit M, Salotti J, Chen J, Bhat A, Gorospe M, Viollet B, Claffey KP, Johnson PF.

Oncogene. 2018 Jun;37(26):3528-3548. doi: 10.1038/s41388-018-0190-7. Epub 2018 Mar 22.

29.

α4 Coordinates Small Intestinal Epithelium Homeostasis by Regulating Stability of HuR.

Chung HK, Wang SR, Xiao L, Rathor N, Turner DJ, Yang P, Gorospe M, Rao JN, Wang JY.

Mol Cell Biol. 2018 May 15;38(11). pii: e00631-17. doi: 10.1128/MCB.00631-17. Print 2018 Jun 1.

30.

Cytoplasmic functions of long noncoding RNAs.

Noh JH, Kim KM, McClusky WG, Abdelmohsen K, Gorospe M.

Wiley Interdiscip Rev RNA. 2018 May;9(3):e1471. doi: 10.1002/wrna.1471. Epub 2018 Mar 8. Review.

31.

Noncoding RNAs in Alzheimer's disease.

Idda ML, Munk R, Abdelmohsen K, Gorospe M.

Wiley Interdiscip Rev RNA. 2018 Mar;9(2). doi: 10.1002/wrna.1463. Epub 2018 Jan 12. Review.

32.

Analysis of Circular RNAs Using the Web Tool CircInteractome.

Panda AC, Dudekula DB, Abdelmohsen K, Gorospe M.

Methods Mol Biol. 2018;1724:43-56. doi: 10.1007/978-1-4939-7562-4_4.

33.

STIM1, but not STIM2, Is the Calcium Sensor Critical for Sweat Secretion.

Cui CY, Noh JH, Michel M, Gorospe M, Schlessinger D.

J Invest Dermatol. 2018 Mar;138(3):704-707. doi: 10.1016/j.jid.2017.09.038. Epub 2017 Oct 17. No abstract available.

34.

Long Noncoding RNA uc.173 Promotes Renewal of the Intestinal Mucosa by Inducing Degradation of MicroRNA 195.

Xiao L, Wu J, Wang JY, Chung HK, Kalakonda S, Rao JN, Gorospe M, Wang JY.

Gastroenterology. 2018 Feb;154(3):599-611. doi: 10.1053/j.gastro.2017.10.009. Epub 2017 Oct 16.

35.

Regulation of HuR structure and function by dihydrotanshinone-I.

Lal P, Cerofolini L, D'Agostino VG, Zucal C, Fuccio C, Bonomo I, Dassi E, Giuntini S, Di Maio D, Vishwakarma V, Preet R, Williams SN, Fairlamb MS, Munk R, Lehrmann E, Abdelmohsen K, Elezgarai SR, Luchinat C, Novellino E, Quattrone A, Biasini E, Manzoni L, Gorospe M, Dixon DA, Seneci P, Marinelli L, Fragai M, Provenzani A.

Nucleic Acids Res. 2017 Sep 19;45(16):9514-9527. doi: 10.1093/nar/gkx623.

36.

Identification of senescent cell surface targetable protein DPP4.

Kim KM, Noh JH, Bodogai M, Martindale JL, Yang X, Indig FE, Basu SK, Ohnuma K, Morimoto C, Johnson PF, Biragyn A, Abdelmohsen K, Gorospe M.

Genes Dev. 2017 Aug 1;31(15):1529-1534. doi: 10.1101/gad.302570.117. Epub 2017 Sep 6.

37.

Senescence-Associated MicroRNAs.

Munk R, Panda AC, Grammatikakis I, Gorospe M, Abdelmohsen K.

Int Rev Cell Mol Biol. 2017;334:177-205. doi: 10.1016/bs.ircmb.2017.03.008. Epub 2017 Apr 28. Review.

PMID:
28838538
38.

RNA-editing enzymes ADAR1 and ADAR2 coordinately regulate the editing and expression of Ctn RNA.

Anantharaman A, Gholamalamdari O, Khan A, Yoon JH, Jantsch MF, Hartner JC, Gorospe M, Prasanth SG, Prasanth KV.

FEBS Lett. 2017 Sep;591(18):2890-2904. doi: 10.1002/1873-3468.12795. Epub 2017 Aug 30.

39.

Cooperative Repression of Insulin-Like Growth Factor Type 2 Receptor Translation by MicroRNA 195 and RNA-Binding Protein CUGBP1.

Zhang Y, Zhang Y, Xiao L, Yu TX, Li JZ, Rao JN, Turner DJ, Gorospe M, Wang JY.

Mol Cell Biol. 2017 Sep 12;37(19). pii: e00225-17. doi: 10.1128/MCB.00225-17. Print 2017 Oct 1.

40.

The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells.

Chen J, Martindale JL, Cramer C, Gorospe M, Atasoy U, Drew PD, Yu S.

J Biol Chem. 2017 Sep 1;292(35):14532-14543. doi: 10.1074/jbc.M117.782771. Epub 2017 Jul 6.

41.

Polysome Fractionation to Analyze mRNA Distribution Profiles.

Panda AC, Martindale JL, Gorospe M.

Bio Protoc. 2017 Feb 5;7(3). pii: e2126. doi: 10.21769/BioProtoc.2126. Erratum in: Bio Protoc. 2019 Feb 5;9(3):.

42.

Affinity Pulldown of Biotinylated RNA for Detection of Protein-RNA Complexes.

Panda AC, Martindale JL, Gorospe M.

Bio Protoc. 2016 Dec 20;6(24). pii: e2062. doi: 10.21769/BioProtoc.2062.

43.

SASP regulation by noncoding RNA.

Panda AC, Abdelmohsen K, Gorospe M.

Mech Ageing Dev. 2017 Dec;168:37-43. doi: 10.1016/j.mad.2017.05.004. Epub 2017 May 11. Review.

44.

LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis.

Kim J, Noh JH, Lee SK, Munk R, Sharov A, Lehrmann E, Zhang Y, Wang W, Abdelmohsen K, Gorospe M.

Oncotarget. 2017 Jul 25;8(30):49409-49420. doi: 10.18632/oncotarget.17219.

45.

WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms.

Lee HC, Jung SH, Hwang HJ, Kang D, De S, Dudekula DB, Martindale JL, Park B, Park SK, Lee EK, Lee JH, Jeong S, Han K, Park HJ, Ko YG, Gorospe M, Lee JS.

Nucleic Acids Res. 2017 Jun 20;45(11):6894-6910. doi: 10.1093/nar/gkx307.

46.

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

Steri M, Orrù V, Idda ML, Pitzalis M, Pala M, Zara I, Sidore C, Faà V, Floris M, Deiana M, Asunis I, Porcu E, Mulas A, Piras MG, Lobina M, Lai S, Marongiu M, Serra V, Marongiu M, Sole G, Busonero F, Maschio A, Cusano R, Cuccuru G, Deidda F, Poddie F, Farina G, Dei M, Virdis F, Olla S, Satta MA, Pani M, Delitala A, Cocco E, Frau J, Coghe G, Lorefice L, Fenu G, Ferrigno P, Ban M, Barizzone N, Leone M, Guerini FR, Piga M, Firinu D, Kockum I, Lima Bomfim I, Olsson T, Alfredsson L, Suarez A, Carreira PE, Castillo-Palma MJ, Marcus JH, Congia M, Angius A, Melis M, Gonzalez A, Alarcón Riquelme ME, da Silva BM, Marchini M, Danieli MG, Del Giacco S, Mathieu A, Pani A, Montgomery SB, Rosati G, Hillert J, Sawcer S, D'Alfonso S, Todd JA, Novembre J, Abecasis GR, Whalen MB, Marrosu MG, Meloni A, Sanna S, Gorospe M, Schlessinger D, Fiorillo E, Zoledziewska M, Cucca F.

N Engl J Med. 2017 Apr 27;376(17):1615-1626. doi: 10.1056/NEJMoa1610528.

47.

High-purity circular RNA isolation method (RPAD) reveals vast collection of intronic circRNAs.

Panda AC, De S, Grammatikakis I, Munk R, Yang X, Piao Y, Dudekula DB, Abdelmohsen K, Gorospe M.

Nucleic Acids Res. 2017 Jul 7;45(12):e116. doi: 10.1093/nar/gkx297.

48.

NSUN2-Mediated m5C Methylation and METTL3/METTL14-Mediated m6A Methylation Cooperatively Enhance p21 Translation.

Li Q, Li X, Tang H, Jiang B, Dou Y, Gorospe M, Wang W.

J Cell Biochem. 2017 Sep;118(9):2587-2598. doi: 10.1002/jcb.25957. Epub 2017 May 3.

49.

TIA-1 RRM23 binding and recognition of target oligonucleotides.

Waris S, García-Mauriño SM, Sivakumaran A, Beckham SA, Loughlin FE, Gorospe M, Díaz-Moreno I, Wilce MCJ, Wilce JA.

Nucleic Acids Res. 2017 May 5;45(8):4944-4957. doi: 10.1093/nar/gkx102.

50.

RNA in extracellular vesicles.

Kim KM, Abdelmohsen K, Mustapic M, Kapogiannis D, Gorospe M.

Wiley Interdiscip Rev RNA. 2017 Jul;8(4). doi: 10.1002/wrna.1413. Epub 2017 Jan 28. Review.

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