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Items: 9

1.

In vitro and in vivo studies on the metabolism of tirofiban.

Vickers S, Theoharides AD, Arison B, Balani SK, Cui D, Duncan CA, Ellis JD, Gorham LM, Polsky SL, Prueksaritanont T, Ramjit HG, Slaughter DE, Vyas KP.

Drug Metab Dispos. 1999 Nov;27(11):1360-6.

PMID:
10534322
2.

In vitro and in vivo evaluations of intestinal barriers for the zwitterion L-767,679 and its carboxyl ester prodrug L-775,318. Roles of efflux and metabolism.

Prueksaritanont T, DeLuna P, Gorham LM, Ma B, Cohn D, Pang J, Xu X, Leung K, Lin JH.

Drug Metab Dispos. 1998 Jun;26(6):520-7.

PMID:
9616186
4.

In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s.

Prueksaritanont T, Gorham LM, Ma B, Liu L, Yu X, Zhao JJ, Slaughter DE, Arison BH, Vyas KP.

Drug Metab Dispos. 1997 Oct;25(10):1191-9.

PMID:
9321523
5.
6.

Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists.

Askew BC, Bednar RA, Bednar B, Claremon DA, Cook JJ, McIntyre CJ, Hunt CA, Gould RJ, Lynch RJ, Lynch JJ Jr, Gaul SL, Stranieri MT, Sitko GR, Holahan MA, Glass JD, Hamill T, Gorham LM, Prueksaritanont T, Baldwin JJ, Hartman GD.

J Med Chem. 1997 Jun 6;40(12):1779-88.

PMID:
9191954
7.

Disposition of L-738,167, a potent and long-acting fibrinogen receptor antagonist, in dogs. Dose-dependent pharmacokinetics.

Prueksaritanont T, Gorham LM, Naue JA, Hamill TG, Askew BC, Vyas KP.

Drug Metab Dispos. 1997 Mar;25(3):355-61.

PMID:
9172954
8.

Species and organ differences in first-pass metabolism of the ester prodrug L-751,164 in dogs and monkeys. In vivo and in vitro studies.

Prueksaritanont T, Gorham LM, Ellis JD, Fernandez-Metzler C, Deluna P, Gehret JR, Strong KL, Hochman JH, Askew BC, Duggan ME, Gilbert JD, Lin JH, Vyas KP.

Drug Metab Dispos. 1996 Nov;24(11):1263-71.

PMID:
8937862
9.

Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells.

Prueksaritanont T, Gorham LM, Hochman JH, Tran LO, Vyas KP.

Drug Metab Dispos. 1996 Jun;24(6):634-42.

PMID:
8781778

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