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Items: 1 to 50 of 375

1.

Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.

Howie HL, Hay AM, de Wolski K, Waterman H, Lebedev J, Fu X, Culp-Hill R, D'Alessandro A, Gorham JD, Ranson MS, Roback JD, Thomson PC, Zimring JC.

Blood Adv. 2019 Aug 13;3(15):2272-2285. doi: 10.1182/bloodadvances.2019000605.

2.

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma.

Ning JF, Stanciu M, Humphrey MR, Gorham J, Wakimoto H, Nishihara R, Lees J, Zou L, Martuza RL, Wakimoto H, Rabkin SD.

Nat Commun. 2019 Jul 2;10(1):2910. doi: 10.1038/s41467-019-10993-5.

3.

The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload.

Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T.

Sci Rep. 2019 Jun 24;9(1):9206. doi: 10.1038/s41598-019-45651-9.

4.

Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.

Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, Lunde IG, Wakimoto H, Smith AM, Toepfer CN, Getz K, Gorham J, Patel P, Ito K, Willcox JA, Arany Z, Li J, Owens AT, Govind R, Nuñez B, Mazaika E, Bayes-Genis A, Walsh R, Finkelman B, Lupon J, Whiffin N, Serrano I, Midwinter W, Wilk A, Bardaji A, Ingold N, Buchan R, Tayal U, Pascual-Figal DA, de Marvao A, Ahmad M, Garcia-Pinilla JM, Pantazis A, Dominguez F, John Baksi A, O'Regan DP, Rosen SD, Prasad SK, Lara-Pezzi E, Provencio M, Lyon AR, Alonso-Pulpon L, Cook SA, DePalma SR, Barton PJR, Aplenc R, Seidman JG, Ky B, Ware JS, Seidman CE.

Circulation. 2019 Jul 2;140(1):31-41. doi: 10.1161/CIRCULATIONAHA.118.037934. Epub 2019 Apr 16.

5.

ORE Identifies Extreme Expression Effects Enriched for Rare Variants.

Richter F, Hoffman GE, Manheimer KB, Patel N, Sharp AJ, McKean D, Morton SU, DePalma S, Gorham J, Kitaygorodksy A, Porter GA, Giardini A, Shen Y, Chung WK, Seidman JG, Seidman CE, Schadt EE, Gelb BD.

Bioinformatics. 2019 Mar 23. pii: btz202. doi: 10.1093/bioinformatics/btz202. [Epub ahead of print]

PMID:
30903145
6.

[Lung cancer: Prognosis in intensive care depends mainly on the acute complication].

Gorham J, Ameye L, Paesmans M, Berghmans T, Sculier JP, Meert AP.

Rev Mal Respir. 2019 Mar;36(3):333-341. doi: 10.1016/j.rmr.2018.05.014. Epub 2019 Mar 18. French.

PMID:
30898468
7.

International assessment of massive transfusion protocol contents and indications for activation.

Thomasson RR, Yazer MH, Gorham JD, Dunbar NM; MTP Use Study Investigators, on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

Transfusion. 2019 May;59(5):1637-1643. doi: 10.1111/trf.15149. Epub 2019 Feb 5.

PMID:
30720872
8.

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.

Toepfer CN, Wakimoto H, Garfinkel AC, McDonough B, Liao D, Jiang J, Tai AC, Gorham JM, Lunde IG, Lun M, Lynch TL 4th, McNamara JW, Sadayappan S, Redwood CS, Watkins HC, Seidman JG, Seidman CE.

Sci Transl Med. 2019 Jan 23;11(476). pii: eaat1199. doi: 10.1126/scitranslmed.aat1199.

PMID:
30674652
9.

Sex differences in gene expression in response to ischemia in the human left ventricular myocardium.

Stone G, Choi A, Meritxell O, Gorham J, Heydarpour M, Seidman CE, Seidman JG, Aranki SF, Body SC, Carey VJ, Raby BA, Stranger BE, Muehlschlegel JD.

Hum Mol Genet. 2019 May 15;28(10):1682-1693. doi: 10.1093/hmg/ddz014.

PMID:
30649309
10.

Approaches for the quantitative analysis of oxidation state in cerium oxide nanomaterials.

Sims CM, Maier RA, Johnston-Peck AC, Gorham JM, Hackley VA, Nelson BC.

Nanotechnology. 2019 Feb 22;30(8):085703. doi: 10.1088/1361-6528/aae364. Epub 2018 Sep 21.

PMID:
30240366
11.

Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers.

Anderson RL, Trivedi DV, Sarkar SS, Henze M, Ma W, Gong H, Rogers CS, Gorham JM, Wong FL, Morck MM, Seidman JG, Ruppel KM, Irving TC, Cooke R, Green EM, Spudich JA.

Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8143-E8152. doi: 10.1073/pnas.1809540115. Epub 2018 Aug 13.

12.

The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.

Gottlieb Sen D, Halu A, Razzaque A, Gorham JM, Hartnett J, Seidman JG, Aikawa E, Seidman CE.

Ann Thorac Surg. 2018 Dec;106(6):1834-1840. doi: 10.1016/j.athoracsur.2018.06.034. Epub 2018 Jul 30.

PMID:
30071238
13.

Droplet Digital PCR with EvaGreen Assay: Confirmational Analysis of Structural Variants.

Tai AC, Parfenov M, Gorham JM.

Curr Protoc Hum Genet. 2018 Apr;97(1):e58. doi: 10.1002/cphg.58.

PMID:
30040209
14.

In vivo and In vitro methods to identify DNA sequence variants that alter RNA Splicing.

Patel PN, Gorham JM, Ito K, Seidman CE.

Curr Protoc Hum Genet. 2018 Apr;97(1). pii: e60. doi: 10.1002/cphg.60. Epub 2018 Apr 26.

15.

Molecular Genetics of Lidocaine-Containing Cardioplegia in the Human Heart During Cardiac Surgery.

Heydarpour M, Ejiofor J, Gilfeather M, Stone G, Gorham J, Seidman CE, Seidman JG, Yammine M, Body SC, Aranki SF, Muehlschlegel JD.

Ann Thorac Surg. 2018 Nov;106(5):1379-1387. doi: 10.1016/j.athoracsur.2018.06.016. Epub 2018 Jul 17.

PMID:
30028983
16.

Surface Properties of Laser-Treated Molybdenum Disulfide Nanosheets for Optoelectronic Applications.

Alrasheed A, Gorham JM, Tran Khac BC, Alsaffar F, DelRio FW, Chung KH, Amer MR.

ACS Appl Mater Interfaces. 2018 May 30;10(21):18104-18112. doi: 10.1021/acsami.8b04717. Epub 2018 May 17.

17.

Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors.

Manheimer KB, Patel N, Richter F, Gorham J, Tai AC, Homsy J, Boskovski MT, Parfenov M, Goldmuntz E, Chung WK, Brueckner M, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE, Gelb BD, Sharp AJ.

Hum Mutat. 2018 Jun;39(6):870-881. doi: 10.1002/humu.23419. Epub 2018 Mar 22.

18.

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3.

Gonzalez Herrera KN, Zaganjor E, Ishikawa Y, Spinelli JB, Yoon H, Lin JR, Satterstrom FK, Ringel A, Mulei S, Souza A, Gorham JM, Benson CC, Seidman JG, Sorger PK, Clish CB, Haigis MC.

Cell Rep. 2018 Feb 20;22(8):1945-1955. doi: 10.1016/j.celrep.2018.01.076.

19.

Robust identification of mosaic variants in congenital heart disease.

Manheimer KB, Richter F, Edelmann LJ, D'Souza SL, Shi L, Shen Y, Homsy J, Boskovski MT, Tai AC, Gorham J, Yasso C, Goldmuntz E, Brueckner M, Lifton RP, Chung WK, Seidman CE, Seidman JG, Gelb BD.

Hum Genet. 2018 Feb;137(2):183-193. doi: 10.1007/s00439-018-1871-6. Epub 2018 Feb 7.

20.

ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients.

Chalkias S, Gorham JM, Mazaika E, Parfenov M, Dang X, DePalma S, McKean D, Seidman CE, Seidman JG, Koralnik IJ.

PLoS One. 2018 Jan 23;13(1):e0186945. doi: 10.1371/journal.pone.0186945. eCollection 2018.

21.

Retinoinvasive Uveal Melanoma: Report of 2 Cases and Review of the Literature.

Gorham JP, Szalai E, Wells JR, Grossniklaus HE.

Ocul Oncol Pathol. 2017 Nov;3(4):292-295. doi: 10.1159/000468940. Epub 2017 Apr 14.

22.

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.

Bick AG, Wakimoto H, Kamer KJ, Sancak Y, Goldberger O, Axelsson A, DeLaughter DM, Gorham JM, Mootha VK, Seidman JG, Seidman CE.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9096-E9104. doi: 10.1073/pnas.1711303114. Epub 2017 Oct 9.

23.

Autoimmune paraneoplastic syndromes associated to lung cancer: A systematic review of the literature: Part 5: Neurological auto-antibodies, discussion, flow chart, conclusions.

Sculier C, Bentea G, Ruelle L, Grigoriu B, Coureau M, Gorham J, Sideris S, Holbrechts S, Lafitte JJ, Meert AP, Durieux V, Berghmans T, Sculier JP.

Lung Cancer. 2017 Sep;111:164-175. doi: 10.1016/j.lungcan.2017.07.026. Epub 2017 Jul 24. Review.

PMID:
28838389
24.

Formation of a Crack-Free, Hybrid Skin Layer with Tunable Surface Topography and Improved Gas Permeation Selectivity on Elastomers Using Gel-Liquid Infiltration Polymerization.

Wang M, Gorham JM, Killgore JP, Omidvar M, Lin H, DelRio FW, Cox LM, Zhang Z, Ding Y.

ACS Appl Mater Interfaces. 2017 Aug 23;9(33):28100-28106. doi: 10.1021/acsami.7b09274. Epub 2017 Aug 10.

PMID:
28758394
25.

Potential effects of brevetoxins and toxic elements on various health variables in Kemp's ridley (Lepidochelys kempii) and green (Chelonia mydas) sea turtles after a red tide bloom event.

Perrault JR, Stacy NI, Lehner AF, Mott CR, Hirsch S, Gorham JC, Buchweitz JP, Bresette MJ, Walsh CJ.

Sci Total Environ. 2017 Dec 15;605-606:967-979. doi: 10.1016/j.scitotenv.2017.06.149. Epub 2017 Jul 6.

PMID:
28693110
26.

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia.

Saddic LA, Nicoloro SM, Gupta OT, Czech MP, Gorham J, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Fitzgibbons TP, Muehlschlegel JD.

Cardiovasc Diabetol. 2017 Jul 7;16(1):87. doi: 10.1186/s12933-017-0567-x.

27.

Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing.

Ito K, Patel PN, Gorham JM, McDonough B, DePalma SR, Adler EE, Lam L, MacRae CA, Mohiuddin SM, Fatkin D, Seidman CE, Seidman JG.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7689-7694. doi: 10.1073/pnas.1707741114. Epub 2017 Jul 5.

28.

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE.

Cell Rep. 2017 Jun 13;19(11):2410. doi: 10.1016/j.celrep.2017.05.038. No abstract available.

29.

Impact of UV irradiation on multiwall carbon nanotubes in nanocomposites: formation of entangled surface layer and mechanisms of release resistance.

Nguyen T, Petersen EJ, Pellegrin B, Gorham JM, Lam T, Zhao M, Sung L.

Carbon N Y. 2017 May;116:191-200. doi: 10.1016/j.carbon.2017.01.097. Epub 2017 Jan 31.

30.

Ecological regime shift drives declining growth rates of sea turtles throughout the West Atlantic.

Bjorndal KA, Bolten AB, Chaloupka M, Saba VS, Bellini C, Marcovaldi MAG, Santos AJB, Bortolon LFW, Meylan AB, Meylan PA, Gray J, Hardy R, Brost B, Bresette M, Gorham JC, Connett S, Crouchley BVS, Dawson M, Hayes D, Diez CE, van Dam RP, Willis S, Nava M, Hart KM, Cherkiss MS, Crowder AG, Pollock C, Hillis-Starr Z, Muñoz Tenería FA, Herrera-Pavón R, Labrada-Martagón V, Lorences A, Negrete-Philippe A, Lamont MM, Foley AM, Bailey R, Carthy RR, Scarpino R, McMichael E, Provancha JA, Brooks A, Jardim A, López-Mendilaharsu M, González-Paredes D, Estrades A, Fallabrino A, Martínez-Souza G, Vélez-Rubio GM, Boulon RH Jr, Collazo JA, Wershoven R, Guzmán Hernández V, Stringell TB, Sanghera A, Richardson PB, Broderick AC, Phillips Q, Calosso M, Claydon JAB, Metz TL, Gordon AL, Landry AM Jr, Shaver DJ, Blumenthal J, Collyer L, Godley BJ, McGowan A, Witt MJ, Campbell CL, Lagueux CJ, Bethel TL, Kenyon L.

Glob Chang Biol. 2017 Nov;23(11):4556-4568. doi: 10.1111/gcb.13712. Epub 2017 Jun 1.

PMID:
28378354
31.

Autoimmune paraneoplastic syndromes associated to lung cancer: A systematic review of the literature: Part 2: Hematologic, cutaneous and vascular syndromes.

Holbrechts S, Gorham J, Sideris S, Meert AP, Durieux V, Berghmans T, Sculier JP.

Lung Cancer. 2017 Apr;106:93-101. doi: 10.1016/j.lungcan.2017.01.016. Epub 2017 Jan 30. Review.

PMID:
28285701
32.

Ultraviolet photo-oxidation of polyvinylpyrrolidone (PVP) coatings on gold nanoparticles.

Louie SM, Gorham JM, Tan J, Hackley VA.

Environ Sci Nano. 2017;4. doi: 10.1039/C7EN00411G.

33.

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE.

Cell Rep. 2016 Dec 20;17(12):3292-3304. doi: 10.1016/j.celrep.2016.11.066. Erratum in: Cell Rep. 2017 Jun 13;19(11):2410.

34.

Single-Cell Resolution of Temporal Gene Expression during Heart Development.

DeLaughter DM, Bick AG, Wakimoto H, McKean D, Gorham JM, Kathiriya IS, Hinson JT, Homsy J, Gray J, Pu W, Bruneau BG, Seidman JG, Seidman CE.

Dev Cell. 2016 Nov 21;39(4):480-490. doi: 10.1016/j.devcel.2016.10.001. Epub 2016 Nov 10.

35.

Comparing distance visual acuity measurement with a novel eye chart and the Landolt C chart in a population of children aged 6-18 years.

Gorham JP, Bruce BB, Hutchinson AK.

Int Ophthalmol. 2017 Dec;37(6):1345-1348. doi: 10.1007/s10792-016-0384-3. Epub 2016 Nov 8.

PMID:
27826937
36.

Surface Degradation and Nanoparticle Release of a Commercial Nanosilica/Polyurethane Coating Under UV Exposure.

Jacobs DS, Huang SR, Cheng YL, Rabb SA, Gorham JM, Krommenhoek PJ, Yu LL, Nguyen T, Sung L.

J Coat Technol Res. 2016 Sep;13(5):735-751. Epub 2016 Jul 13.

37.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA Jr, Anders RA, Sosman JA, Moslehi JJ.

N Engl J Med. 2016 Nov 3;375(18):1749-1755.

38.
39.

Loss of RNA expression and allele-specific expression associated with congenital heart disease.

McKean DM, Homsy J, Wakimoto H, Patel N, Gorham J, DePalma SR, Ware JS, Zaidi S, Ma W, Patel N, Lifton RP, Chung WK, Kim R, Shen Y, Brueckner M, Goldmuntz E, Sharp AJ, Seidman CE, Gelb BD, Seidman JG.

Nat Commun. 2016 Sep 27;7:12824. doi: 10.1038/ncomms12824.

40.

[A 38 years old female with inflammatory myofibroblastic tumor and lactic acidosis].

Gorham J, Liberale G, Haydar HN, De Saint Aubain N, Meert AP.

Rev Med Brux. 2016 Mar-Apr;37(2):104-7. French.

PMID:
27487696
41.

Addition of arabinoxylan and mixed linkage glucans in porcine diets affects the large intestinal bacterial populations.

Gorham JB, Kang S, Williams BA, Grant LJ, McSweeney CS, Gidley MJ, Mikkelsen D.

Eur J Nutr. 2017 Sep;56(6):2193-2206. doi: 10.1007/s00394-016-1263-4. Epub 2016 Jul 11.

PMID:
27401929
42.

Molecular profiling of dilated cardiomyopathy that progresses to heart failure.

Burke MA, Chang S, Wakimoto H, Gorham JM, Conner DA, Christodoulou DC, Parfenov MG, DePalma SR, Eminaga S, Konno T, Seidman JG, Seidman CE.

JCI Insight. 2016 May 5;1(6). pii: e86898.

43.

Comparison of the Handy Eye Chart and the Lea Symbols Chart in a population of deaf children aged 7-18 years.

Gorham JP, Bruce BB, Hutchinson AK.

J AAPOS. 2016 Jun;20(3):243-6. doi: 10.1016/j.jaapos.2016.02.009. Epub 2016 May 6.

44.

[The Glasgow inflammatory score and lung cancer: A predictor of admissions to emergency units].

Gorham J, Ameye L, Paesmans M, Berghmans T, Sculier JP, Meert AP.

Rev Mal Respir. 2016 Nov;33(9):759-765. doi: 10.1016/j.rmr.2016.02.004. Epub 2016 Mar 24. French.

PMID:
27017064
45.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE.

Science. 2016 Feb 5;351(6273):617-21. doi: 10.1126/science.aad3456.

46.

Intactness of cell wall structure controls the in vitro digestion of starch in legumes.

Dhital S, Bhattarai RR, Gorham J, Gidley MJ.

Food Funct. 2016 Mar;7(3):1367-79. doi: 10.1039/c5fo01104c.

PMID:
26786854
47.

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.

Homsy J, Zaidi S, Shen Y, Ware JS, Samocha KE, Karczewski KJ, DePalma SR, McKean D, Wakimoto H, Gorham J, Jin SC, Deanfield J, Giardini A, Porter GA Jr, Kim R, Bilguvar K, López-Giráldez F, Tikhonova I, Mane S, Romano-Adesman A, Qi H, Vardarajan B, Ma L, Daly M, Roberts AE, Russell MW, Mital S, Newburger JW, Gaynor JW, Breitbart RE, Iossifov I, Ronemus M, Sanders SJ, Kaltman JR, Seidman JG, Brueckner M, Gelb BD, Goldmuntz E, Lifton RP, Seidman CE, Chung WK.

Science. 2015 Dec 4;350(6265):1262-6. doi: 10.1126/science.aac9396.

48.

"SHOUT" to improve the quality of care delivered to patients with acute kidney injury at Great Western Hospital.

Brady P, Gorham J, Kosti A, Seligman W, Courtney A, Mazan K, Paterson S, Ramcharitar S, Chandrasekaran B, Juniper M, Greamspet M, Daniel J, Chalstrey S, Ahmed I, Dasgupta T.

BMJ Qual Improv Rep. 2015 Nov 17;4(1). pii: u207938.w3198. doi: 10.1136/bmjquality.u207938.w3198. eCollection 2015.

49.

[Oncological intensive care: 2013 and 2014 years'review].

Sculier JP, Bucalau AM, Closset C, Compagnie M, Gorham J, Sideris S, De Roodebeek DT, Wang XX, Berghmans T, Meert AP.

Rev Med Brux. 2016;37(3):159-167. Review. French.

PMID:
28525189
50.

Circulating free DNA, new dynamic marker in nonsmall cell lung cancer patients?

Remon J, Gorham J, Besse B, Sculier JP.

Eur Respir J. 2015 Dec;46(6):1548-50. doi: 10.1183/13993003.01482-2015. No abstract available.

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