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Items: 21


Intra-Patient Heterogeneity of Circulating Tumor Cells and Circulating Tumor DNA in Blood of Melanoma Patients.

Gorges K, Wiltfang L, Gorges TM, Sartori A, Hildebrandt L, Keller L, Volkmer B, Peine S, Babayan A, Moll I, Schneider SW, Twarock S, Mohr P, Fischer JW, Pantel K.

Cancers (Basel). 2019 Oct 29;11(11). pii: E1685. doi: 10.3390/cancers11111685.


Tumor-Associated Release of Prostatic Cells into the Blood after Transrectal Ultrasound-Guided Biopsy in Patients with Histologically Confirmed Prostate Cancer.

Joosse SA, Beyer B, Gasch C, Nastały P, Kuske A, Isbarn H, Horst LJ, Hille C, Gorges TM, Cayrefourcq L, Alix-Panabières C, Tennstedt P, Riethdorf S, Schlomm T, Pantel K.

Clin Chem. 2019 Oct 10. pii: clinchem.2019.310912. doi: 10.1373/clinchem.2019.310912. [Epub ahead of print]


Detection of Androgen Receptor Variant 7 (ARV7) mRNA Levels in EpCAM-Enriched CTC Fractions for Monitoring Response to Androgen Targeting Therapies in Prostate Cancer.

Hille C, Gorges TM, Riethdorf S, Mazel M, Steuber T, Amsberg GV, König F, Peine S, Alix-Panabières C, Pantel K.

Cells. 2019 Sep 11;8(9). pii: E1067. doi: 10.3390/cells8091067.


Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors.

Janning M, Kobus F, Babayan A, Wikman H, Velthaus JL, Bergmann S, Schatz S, Falk M, Berger LA, Böttcher LM, Päsler S, Gorges TM, O'Flaherty L, Hille C, Joosse SA, Simon R, Tiemann M, Bokemeyer C, Reck M, Riethdorf S, Pantel K, Loges S.

Cancers (Basel). 2019 Jun 17;11(6). pii: E835. doi: 10.3390/cancers11060835.


In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells.

El-Heliebi A, Hille C, Laxman N, Svedlund J, Haudum C, Ercan E, Kroneis T, Chen S, Smolle M, Rossmann C, Krzywkowski T, Ahlford A, Darai E, von Amsberg G, Alsdorf W, König F, Löhr M, de Kruijff I, Riethdorf S, Gorges TM, Pantel K, Bauernhofer T, Nilsson M, Sedlmayr P.

Clin Chem. 2018 Mar;64(3):536-546. doi: 10.1373/clinchem.2017.281295. Epub 2018 Jan 4.


Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients.

Markou A, Lazaridou M, Paraskevopoulos P, Chen S, Świerczewska M, Budna J, Kuske A, Gorges TM, Joosse SA, Kroneis T, Zabel M, Sedlmayr P, Alix-Panabières C, Pantel K, Lianidou ES.

Clin Chem. 2018 Feb;64(2):297-306. doi: 10.1373/clinchem.2017.275503. Epub 2017 Nov 9.


Improved detection of circulating tumor cells in non-metastatic high-risk prostate cancer patients.

Kuske A, Gorges TM, Tennstedt P, Tiebel AK, Pompe R, Preißer F, Prues S, Mazel M, Markou A, Lianidou E, Peine S, Alix-Panabières C, Riethdorf S, Beyer B, Schlomm T, Pantel K.

Sci Rep. 2016 Dec 21;6:39736. doi: 10.1038/srep39736.


Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells.

Gorges TM, Kuske A, Röck K, Mauermann O, Müller V, Peine S, Verpoort K, Novosadova V, Kubista M, Riethdorf S, Pantel K.

Clin Chem. 2016 Nov;62(11):1504-1515. Epub 2016 Sep 14.


Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer.

Gasch C, Oldopp T, Mauermann O, Gorges TM, Andreas A, Coith C, Müller V, Fehm T, Janni W, Pantel K, Riethdorf S.

Mol Oncol. 2016 Oct;10(8):1330-43. doi: 10.1016/j.molonc.2016.07.005. Epub 2016 Jul 22.


Characterization of different CTC subpopulations in non-small cell lung cancer.

Hanssen A, Wagner J, Gorges TM, Taenzer A, Uzunoglu FG, Driemel C, Stoecklein NH, Knoefel WT, Angenendt S, Hauch S, Atanackovic D, Loges S, Riethdorf S, Pantel K, Wikman H.

Sci Rep. 2016 Jun 15;6:28010. doi: 10.1038/srep28010.


Improved Detection of Circulating Tumor Cells in Metastatic Colorectal Cancer by the Combination of the CellSearch® System and the AdnaTest®.

Gorges TM, Stein A, Quidde J, Hauch S, Röck K, Riethdorf S, Joosse SA, Pantel K.

PLoS One. 2016 May 16;11(5):e0155126. doi: 10.1371/journal.pone.0155126. eCollection 2016.


Heterogeneous PSMA expression on circulating tumor cells: a potential basis for stratification and monitoring of PSMA-directed therapies in prostate cancer.

Gorges TM, Riethdorf S, von Ahsen O, Nastał Y P, Röck K, Boede M, Peine S, Kuske A, Schmid E, Kneip C, König F, Rudolph M, Pantel K.

Oncotarget. 2016 Jun 7;7(23):34930-41. doi: 10.18632/oncotarget.9004.


A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells.

Hvichia GE, Parveen Z, Wagner C, Janning M, Quidde J, Stein A, Müller V, Loges S, Neves RP, Stoecklein NH, Wikman H, Riethdorf S, Pantel K, Gorges TM.

Int J Cancer. 2016 Jun 15;138(12):2894-904. doi: 10.1002/ijc.30007. Epub 2016 Feb 26.


Enumeration and Molecular Characterization of Tumor Cells in Lung Cancer Patients Using a Novel In Vivo Device for Capturing Circulating Tumor Cells.

Gorges TM, Penkalla N, Schalk T, Joosse SA, Riethdorf S, Tucholski J, Lücke K, Wikman H, Jackson S, Brychta N, von Ahsen O, Schumann C, Krahn T, Pantel K.

Clin Cancer Res. 2016 May 1;22(9):2197-206. doi: 10.1158/1078-0432.CCR-15-1416. Epub 2015 Dec 14.


Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response.

Bartkowiak K, Kwiatkowski M, Buck F, Gorges TM, Nilse L, Assmann V, Andreas A, Müller V, Wikman H, Riethdorf S, Schlüter H, Pantel K.

Cancer Res. 2015 Dec 15;75(24):5367-77. doi: 10.1158/0008-5472.CAN-14-3728. Epub 2015 Nov 16.


A Versatile Microarray Platform for Capturing Rare Cells.

Brinkmann F, Hirtz M, Haller A, Gorges TM, Vellekoop MJ, Riethdorf S, Müller V, Pantel K, Fuchs H.

Sci Rep. 2015 Oct 23;5:15342. doi: 10.1038/srep15342.


Circulating tumour cell-derived plastin3 is a novel marker for predicting long-term prognosis in patients with breast cancer.

Ueo H, Sugimachi K, Gorges TM, Bartkowiak K, Yokobori T, Müller V, Shinden Y, Ueda M, Ueo H, Mori M, Kuwano H, Maehara Y, Ohno S, Pantel K, Mimori K.

Br J Cancer. 2015 Apr 28;112(9):1519-26. doi: 10.1038/bjc.2015.132. Epub 2015 Apr 16.


Biology, detection, and clinical implications of circulating tumor cells.

Joosse SA, Gorges TM, Pantel K.

EMBO Mol Med. 2015 Jan;7(1):1-11. doi: 10.15252/emmm.201303698. Review.


Circulating tumor cells as therapy-related biomarkers in cancer patients.

Gorges TM, Pantel K.

Cancer Immunol Immunother. 2013 May;62(5):931-9. doi: 10.1007/s00262-012-1387-1. Epub 2013 Jan 12. Review.


Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA.

Gorges TM, Schiller J, Schmitz A, Schuetzmann D, Schatz C, Zollner TM, Krahn T, von Ahsen O.

Biomarkers. 2012 Sep;17(6):498-506. doi: 10.3109/1354750X.2012.689133. Epub 2012 May 23.


Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition.

Gorges TM, Tinhofer I, Drosch M, Röse L, Zollner TM, Krahn T, von Ahsen O.

BMC Cancer. 2012 May 16;12:178. doi: 10.1186/1471-2407-12-178.

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