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Items: 1 to 50 of 151

1.

Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000-2019: protocol for systematic review.

Kalata NL, Nyazika TK, Swarthout TD, Everett D, French N, Heyderman RS, Gordon SB, Jambo KC.

BMJ Open. 2019 Nov 13;9(11):e030981. doi: 10.1136/bmjopen-2019-030981.

2.

Nasal Pneumococcal Density is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.

Mitsi E, Carniel B, Reiné J, Rylance J, Zaidi S, Soares-Schanoski A, Connor V, Collins AM, Schlitzer A, Nikolaou E, Solórzano C, Pojar S, Hill H, Hyder-Wright AD, Jambo KC, Oggioni MR, De Ste Croix M, Gordon SB, Jochems SP, Ferreira DM.

Am J Respir Crit Care Med. 2019 Oct 18. doi: 10.1164/rccm.201903-0607OC. [Epub ahead of print]

PMID:
31626559
3.

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.

Jochems SP, de Ruiter K, Solórzano C, Voskamp A, Mitsi E, Nikolaou E, Carniel BF, Pojar S, German EL, Reiné J, Soares-Schanoski A, Hill H, Robinson R, Hyder-Wright AD, Weight CM, Durrenberger PF, Heyderman RS, Gordon SB, Smits HH, Urban BC, Rylance J, Collins AM, Wilkie MD, Lazarova L, Leong SC, Yazdanbakhsh M, Ferreira DM.

J Clin Invest. 2019 Jul 30;130:4523-4538. doi: 10.1172/JCI128865.

4.

The Malawi NCD BRITE Consortium: Building Research Capacity, Implementation, and Translation Expertise for Noncommunicable Diseases.

van Oosterhout JJ, Hosseinipour M, Muula AS, Amberbir A, Wroe E, Berman J, Maliwichi-Nyirenda C, Mwapasa V, Crampin A, Makwero M, Singogo E, Gopal S, Baker U, Phiri S, Gordon SB, Tobe S, Chiwanda J, Masiye J, Parks J, Mitambo C, Gondwe A, Dullie L, Newsome B, Nyirenda M.

Glob Heart. 2019 Jun;14(2):149-154. doi: 10.1016/j.gheart.2019.05.004. Review.

PMID:
31324369
5.

Protective effect of PCV vaccine against experimental pneumococcal challenge in adults is primarily mediated by controlling colonisation density.

German EL, Solórzano C, Sunny S, Dunne F, Gritzfeld JF, Mitsi E, Nikolaou E, Hyder-Wright AD, Collins AM, Gordon SB, Ferreira DM.

Vaccine. 2019 Jul 9;37(30):3953-3956. doi: 10.1016/j.vaccine.2019.05.080. Epub 2019 Jun 5.

6.

Strengthening ethical community engagement in contemporary Malawi.

Nyirenda D, Gooding K, Sambakunsi R, Seyama L, Mfutso-Bengo J, Manda Taylor L, Gordon SB, Parker M.

Version 2. Wellcome Open Res. 2019 Mar 18 [revised 2019 Jan 1];3:115. doi: 10.12688/wellcomeopenres.14793.2. eCollection 2018.

7.

Nonspecific effects of oral vaccination with live-attenuated Salmonella Typhi strain Ty21a.

Pennington SH, Ferreira DM, Caamaño-Gutiérrez E, Reiné J, Hewitt C, Hyder-Wright AD, Gordon SB, Gordon MA.

Sci Adv. 2019 Feb 27;5(2):eaau6849. doi: 10.1126/sciadv.aau6849. eCollection 2019 Feb.

8.

A Haemophilus sp. dominates the microbiota of sputum from UK adults with non-severe community acquired pneumonia and chronic lung disease.

Wootton DG, Cox MJ, Gloor GB, Litt D, Hoschler K, German E, Court J, Eneje O, Keogan L, Macfarlane L, Wilks S, Diggle PJ, Woodhead M, Moffatt MF, Cookson WOC, Gordon SB.

Sci Rep. 2019 Feb 20;9(1):2388. doi: 10.1038/s41598-018-38090-5.

9.

Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.

Adler H, Nikolaou E, Gould K, Hinds J, Collins AM, Connor V, Hales C, Hill H, Hyder-Wright AD, Zaidi SR, German EL, Gritzfeld JF, Mitsi E, Pojar S, Gordon SB, Roberts AP, Rylance J, Ferreira DM.

J Infect Dis. 2019 May 24;219(12):1989-1993. doi: 10.1093/infdis/jiz034.

10.

A Malawi guideline for research study participant remuneration.

Gordon SB, Chinula L, Chilima B, Mwapasa V, Dadabhai S, Mlombe Y; Malawi Research Ethics Workshop 2018 Participants.

Version 2. Wellcome Open Res. 2018 Dec 19 [revised 2018 Jan 1];3:141. doi: 10.12688/wellcomeopenres.14668.2. eCollection 2018.

11.

Etiology and Risk Factors for Mortality in an Adult Community-acquired Pneumonia Cohort in Malawi.

Aston SJ, Ho A, Jary H, Huwa J, Mitchell T, Ibitoye S, Greenwood S, Joekes E, Daire A, Mallewa J, Everett D, Nyirenda M, Faragher B, Mwandumba HC, Heyderman RS, Gordon SB.

Am J Respir Crit Care Med. 2019 Aug 1;200(3):359-369. doi: 10.1164/rccm.201807-1333OC.

12.

Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.

Jochems SP, Marcon F, Carniel BF, Holloway M, Mitsi E, Smith E, Gritzfeld JF, Solórzano C, Reiné J, Pojar S, Nikolaou E, German EL, Hyder-Wright A, Hill H, Hales C, de Steenhuijsen Piters WAA, Bogaert D, Adler H, Zaidi S, Connor V, Gordon SB, Rylance J, Nakaya HI, Ferreira DM.

Nat Immunol. 2018 Dec;19(12):1299-1308. doi: 10.1038/s41590-018-0231-y. Epub 2018 Oct 29.

13.

The Cooking and Pneumonia Study (CAPS) in Malawi: A Cross-Sectional Assessment of Carbon Monoxide Exposure and Carboxyhemoglobin Levels in Children under 5 Years Old.

Havens D, Wang D, Grigg J, Gordon SB, Balmes J, Mortimer K.

Int J Environ Res Public Health. 2018 Sep 5;15(9). pii: E1936. doi: 10.3390/ijerph15091936.

14.

Anti-protein immunoglobulin M responses to pneumococcus are not associated with aging.

German EL, Al-Hakim B, Mitsi E, Pennington SH, Gritzfeld JF, Hyder-Wright AD, Banyard A, Gordon SB, Collins AM, Ferreira DM.

Pneumonia (Nathan). 2018 Jun 5;10:5. doi: 10.1186/s41479-018-0048-3. eCollection 2018.

15.

Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a.

Pennington SH, Ferreira DM, Reiné J, Nyirenda TS, Thompson AL, Hancock CA, Wright AD, Gordon SB, Gordon MA.

Vaccine. 2018 Jul 25;36(31):4725-4733. doi: 10.1016/j.vaccine.2018.05.114. Epub 2018 Jun 27.

16.

Use of cleaner-burning biomass stoves and airway macrophage black carbon in Malawian women.

Whitehouse AL, Miyashita L, Liu NM, Lesosky M, Flitz G, Ndamala C, Balmes JR, Gordon SB, Mortimer K, Grigg J.

Sci Total Environ. 2018 Sep 1;635:405-411. doi: 10.1016/j.scitotenv.2018.04.125. Epub 2018 Apr 24.

17.

Household air pollution, chronic respiratory disease and pneumonia in Malawian adults: A case-control study.

Jary HR, Aston S, Ho A, Giorgi E, Kalata N, Nyirenda M, Mallewa J, Peterson I, Gordon SB, Mortimer K.

Wellcome Open Res. 2017 Oct 24;2:103. doi: 10.12688/wellcomeopenres.12621.1. eCollection 2017.

18.

ERS/ATS workshop report on respiratory health effects of household air pollution.

Sood A, Assad NA, Barnes PJ, Churg A, Gordon SB, Harrod KS, Irshad H, Kurmi OP, Martin WJ 2nd, Meek P, Mortimer K, Noonan CW, Perez-Padilla R, Smith KR, Tesfaigzi Y, Ward T, Balmes J.

Eur Respir J. 2018 Jan 4;51(1). pii: 1700698. doi: 10.1183/13993003.00698-2017. Print 2018 Jan.

19.

How Do We "Help the World Breathe"?

Gordon SB, Buist AS, Hopewell P, Pinkerton K, Sly P, West TE, Moschovis P, Accinelli RA, Cruz ÁA, Adhikari NKJ; International Health Committee of the American Thoracic Society.

Am J Respir Crit Care Med. 2017 Nov 1;196(9):1100-1102. doi: 10.1164/rccm.201706-1174ED. No abstract available.

PMID:
29090965
20.

A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi.

Gordon SB, Rylance J, Luck A, Jambo K, Ferreira DM, Manda-Taylor L, Bejon P, Ngwira B, Littler K, Seager Z, Gibani M, Gmeiner M, Roestenberg M, Mlombe Y; Wellcome Trust CHIM workshop participants.

Wellcome Open Res. 2017 Aug 24;2:70. doi: 10.12688/wellcomeopenres.12256.1. eCollection 2017.

21.

A longitudinal modelling study estimates acute symptoms of community acquired pneumonia recover to baseline by 10 days.

Wootton DG, Dickinson L, Pertinez H, Court J, Eneje O, Keogan L, Macfarlane L, Wilks S, Gallagher J, Woodhead M, Gordon SB, Diggle PJ.

Eur Respir J. 2017 Jun 15;49(6). pii: 1602170. doi: 10.1183/13993003.02170-2016. Print 2017 Jun.

22.

Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591).

Zaidi SR, Collins AM, Mitsi E, Reiné J, Davies K, Wright AD, Owugha J, Fitzgerald R, Ganguli A, Gordon SB, Ferreira DM, Rylance J.

BMC Pulm Med. 2017 May 5;17(1):83. doi: 10.1186/s12890-017-0421-7.

23.

Pneumococcal Capsular Polysaccharide Immunity in the Elderly.

Adler H, Ferreira DM, Gordon SB, Rylance J.

Clin Vaccine Immunol. 2017 Jun 5;24(6). pii: e00004-17. doi: 10.1128/CVI.00004-17. Print 2017 Jun. Review.

24.

Exhaled carbon monoxide: a non-invasive biomarker of short-term exposure to outdoor air pollution.

Lawin H, Ayi Fanou L, Hinson V, Wanjiku J, Ukwaja NK, Gordon SB, Fayomi B, Balmes JR, Houngbegnon P, Avokpaho E, Sanni A.

BMC Public Health. 2017 Apr 17;17(1):320. doi: 10.1186/s12889-017-4243-6.

25.

Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash.

Jochems SP, Piddock K, Rylance J, Adler H, Carniel BF, Collins A, Gritzfeld JF, Hancock C, Hill H, Reiné J, Seddon A, Solórzano C, Sunny S, Trimble A, Wright AD, Zaidi S, Gordon SB, Ferreira DM.

PLoS One. 2017 Jan 20;12(1):e0169805. doi: 10.1371/journal.pone.0169805. eCollection 2017.

26.

A cleaner burning biomass-fuelled cookstove intervention to prevent pneumonia in children under 5 years old in rural Malawi (the Cooking and Pneumonia Study): a cluster randomised controlled trial.

Mortimer K, Ndamala CB, Naunje AW, Malava J, Katundu C, Weston W, Havens D, Pope D, Bruce NG, Nyirenda M, Wang D, Crampin A, Grigg J, Balmes J, Gordon SB.

Lancet. 2017 Jan 14;389(10065):167-175. doi: 10.1016/S0140-6736(16)32507-7. Epub 2016 Dec 7.

27.

A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults.

French N, Gordon SB, Mwalukomo T, White SA, Mwafulirwa G, Longwe H, Mwaiponya M, Zijlstra EE, Molyneux ME, Gilks CF.

Malawi Med J. 2016 Sep;28(3):115-122.

28.

Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage.

Mitsi E, Roche AM, Reiné J, Zangari T, Owugha JT, Pennington SH, Gritzfeld JF, Wright AD, Collins AM, van Selm S, de Jonge MI, Gordon SB, Weiser JN, Ferreira DM.

Mucosal Immunol. 2017 Mar;10(2):385-394. doi: 10.1038/mi.2016.71. Epub 2016 Aug 31.

29.

Household air pollution and the lung microbiome of healthy adults in Malawi: a cross-sectional study.

Rylance J, Kankwatira A, Nelson DE, Toh E, Day RB, Lin H, Gao X, Dong Q, Sodergren E, Weinstock GM, Heyderman RS, Twigg HL 3rd, Gordon SB.

BMC Microbiol. 2016 Aug 11;16(1):182. doi: 10.1186/s12866-016-0803-7.

30.

Augmented Passive Immunotherapy with P4 Peptide Improves Phagocyte Activity in Severe Sepsis.

Morton B, Mitsi E, Pennington SH, Reiné J, Wright AD, Parker R, Welters ID, Blakey JD, Rajam G, Ades EW, Ferreira DM, Wang D, Kadioglu A, Gordon SB.

Shock. 2016 Dec;46(6):635-641.

PMID:
27488089
31.

Neuraminidase A-Exposed Galactose Promotes Streptococcus pneumoniae Biofilm Formation during Colonization.

Blanchette KA, Shenoy AT, Milner J 2nd, Gilley RP, McClure E, Hinojosa CA, Kumar N, Daugherty SC, Tallon LJ, Ott S, King SJ, Ferreira DM, Gordon SB, Tettelin H, Orihuela CJ.

Infect Immun. 2016 Sep 19;84(10):2922-32. doi: 10.1128/IAI.00277-16. Print 2016 Oct.

32.

Recovery from pneumonia requires efferocytosis which is impaired in smokers and those with low body mass index and enhanced by statins.

Wootton DG, Diggle PJ, Court J, Eneje O, Keogan L, Macfarlane L, Wilks S, Woodhead M, Gordon SB.

Thorax. 2016 Nov;71(11):1052-1054. doi: 10.1136/thoraxjnl-2016-208505. Epub 2016 Jul 28.

33.

Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.

Pennington SH, Pojar S, Mitsi E, Gritzfeld JF, Nikolaou E, Solórzano C, Owugha JT, Masood Q, Gordon MA, Wright AD, Collins AM, Miyaji EN, Gordon SB, Ferreira DM.

Am J Respir Crit Care Med. 2016 Dec 15;194(12):1523-1531.

34.

Oxygen saturations of medical inpatients in a Malawian hospital: cross-sectional study of oxygen supply and demand.

Evans HT, Mahmood N, Fullerton DG, Rylance J, Gonani A, Gordon SB, Mortimer K, Allain TJ.

Pneumonia (Nathan). 2016 Jul 2;1:3-6. doi: 10.15172/pneu.2012.1/208. eCollection 2012.

35.

A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA.

Aljurayyan AN, Sharma R, Upile N, Beer H, Vaughan C, Xie C, Achar P, Ahmed MS, McNamara PS, Gordon SB, Zhang Q.

Antiviral Res. 2016 Aug;132:122-30. doi: 10.1016/j.antiviral.2016.05.021. Epub 2016 May 28.

PMID:
27247060
36.

Clinical trials: The mathematics of falling vaccine efficacy with rising disease incidence.

Gomes MGM, Gordon SB, Lalloo DG.

Vaccine. 2016 Jun 8;34(27):3007-3009. doi: 10.1016/j.vaccine.2016.04.065. Epub 2016 May 10. No abstract available.

37.

Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa.

Pennington SH, Thompson AL, Wright AK, Ferreira DM, Jambo KC, Wright AD, Faragher B, Gilmour JW, Gordon SB, Gordon MA.

J Infect Dis. 2016 Jun 1;213(11):1809-19. doi: 10.1093/infdis/jiw030. Epub 2016 Jan 24.

38.

Pneumococcal Colonization Rates in Patients Admitted to a United Kingdom Hospital with Lower Respiratory Tract Infection: a Prospective Case-Control Study.

Collins AM, Johnstone CM, Gritzfeld JF, Banyard A, Hancock CA, Wright AD, Macfarlane L, Ferreira DM, Gordon SB.

J Clin Microbiol. 2016 Apr;54(4):944-9. doi: 10.1128/JCM.02008-15. Epub 2016 Jan 20.

39.

Noncommunicable Lung Disease in Sub-Saharan Africa. A Community-based Cross-Sectional Study of Adults in Urban Malawi.

Meghji J, Nadeau G, Davis KJ, Wang D, Nyirenda MJ, Gordon SB, Mortimer K.

Am J Respir Crit Care Med. 2016 Jul 1;194(1):67-76. doi: 10.1164/rccm.201509-1807OC.

40.

Comparison of methods for the analysis of airway macrophage particulate load from induced sputum, a potential biomarker of air pollution exposure.

Jary H, Rylance J, Patel L, Gordon SB, Mortimer K.

BMC Pulm Med. 2015 Nov 5;15:137. doi: 10.1186/s12890-015-0135-7.

41.

Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers.

Rylance J, Chimpini C, Semple S, Russell DG, Jackson MJ, Heyderman RS, Gordon SB.

PLoS One. 2015 Sep 25;10(9):e0138762. doi: 10.1371/journal.pone.0138762. eCollection 2015.

42.

A Feasibility Study to Determine Whether Clinical Contrast Enhanced Magnetic Resonance Imaging can Detect Increased Bladder Permeability in Patients with Interstitial Cystitis.

Towner RA, Wisniewski AB, Wu DH, Van Gordon SB, Smith N, North JC, McElhaney R, Aston CE, Shobeiri SA, Kropp BP, Greenwood-Van Meerveld B, Hurst RE.

J Urol. 2016 Mar;195(3):631-8. doi: 10.1016/j.juro.2015.08.077. Epub 2015 Aug 22.

43.

Assessment of colon and bladder crosstalk in an experimental colitis model using contrast-enhanced magnetic resonance imaging.

Towner RA, Smith N, Saunders D, Van Gordon SB, Tyler KR, Wisniewski AB, Greenwood-Van Meerveld B, Hurst RE.

Neurogastroenterol Motil. 2015 Nov;27(11):1571-9. doi: 10.1111/nmo.12654. Epub 2015 Aug 24.

44.

First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial.

Collins AM, Wright AD, Mitsi E, Gritzfeld JF, Hancock CA, Pennington SH, Wang D, Morton B, Ferreira DM, Gordon SB.

Am J Respir Crit Care Med. 2015 Oct 1;192(7):853-8. doi: 10.1164/rccm.201503-0542OC.

PMID:
26114410
45.

Minimum incidence of adult invasive pneumococcal disease in Blantyre, Malawi an urban african setting: a hospital based prospective cohort study.

Bar-Zeev N, Mtunthama N, Gordon SB, Mwafulirwa G, French N.

PLoS One. 2015 Jun 3;10(6):e0128738. doi: 10.1371/journal.pone.0128738. eCollection 2015.

46.

Genetic stability of pneumococcal isolates during 35 days of human experimental carriage.

Gladstone RA, Gritzfeld JF, Coupland P, Gordon SB, Bentley SD.

Vaccine. 2015 Jun 26;33(29):3342-5. doi: 10.1016/j.vaccine.2015.05.021. Epub 2015 May 23.

47.

Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriage.

Glennie S, Gritzfeld JF, Pennington SH, Garner-Jones M, Coombes N, Hopkins MJ, Vadesilho CF, Miyaji EN, Wang D, Wright AD, Collins AM, Gordon SB, Ferreira DM.

Mucosal Immunol. 2016 Jan;9(1):56-67. doi: 10.1038/mi.2015.35. Epub 2015 Apr 29.

48.

The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition.

Cremers AJ, Zomer AL, Gritzfeld JF, Ferwerda G, van Hijum SA, Ferreira DM, Shak JR, Klugman KP, Boekhorst J, Timmerman HM, de Jonge MI, Gordon SB, Hermans PW.

Microbiome. 2014 Dec 15;2:44. doi: 10.1186/2049-2618-2-44. eCollection 2014.

49.

Contrast enhanced magnetic resonance imaging as a diagnostic tool to assess bladder permeability and associated colon cross talk: preclinical studies in a rat model.

Towner RA, Smith N, Saunders D, Van Gordon SB, Wisniewski AB, Tyler KR, Greenwood-Van Meerveld B, Hurst RE.

J Urol. 2015 Apr;193(4):1394-400. doi: 10.1016/j.juro.2014.10.120. Epub 2014 Nov 14.

50.

Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages.

Rylance J, Fullerton DG, Scriven J, Aljurayyan AN, Mzinza D, Barrett S, Wright AK, Wootton DG, Glennie SJ, Baple K, Knott A, Mortimer K, Russell DG, Heyderman RS, Gordon SB.

Am J Respir Cell Mol Biol. 2015 May;52(5):584-93. doi: 10.1165/rcmb.2014-0188OC.

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