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Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets.

Aulicino A, Rue-Albrecht KC, Preciado-Llanes L, Napolitani G, Ashley N, Cribbs A, Koth J, Lagerholm BC, Ambrose T, Gordon MA, Sims D, Simmons A.

Nat Commun. 2018 Nov 19;9(1):4883. doi: 10.1038/s41467-018-07329-0.


Five-year single-centre experience of carcinoma of the oesophagus from Blantyre, Malawi.

Chetwood JD, Finch PJ, Kankwatira A, Mallewa J, Gordon MA, Masamba L.

BMJ Open Gastroenterol. 2018 Oct 15;5(1):e000232. doi: 10.1136/bmjgast-2018-000232. eCollection 2018.


Epidemiology of hepatitis B, C and D in Malawi: systematic review.

Stockdale AJ, Mitambo C, Everett D, Geretti AM, Gordon MA.

BMC Infect Dis. 2018 Oct 12;18(1):516. doi: 10.1186/s12879-018-3428-7.


The long non-coding RNA MALAT1 promotes ovarian cancer progression by regulating RBFOX2-mediated alternative splicing.

Gordon MA, Babbs B, Cochrane DR, Bitler BG, Richer JK.

Mol Carcinog. 2018 Oct 8. doi: 10.1002/mc.22919. [Epub ahead of print]


Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial.

Paris M, Silva M, Añez-Nava L, Jaramillo Y, Kiluk BD, Gordon MA, Nich C, Frankforter T, Devore K, Ball SA, Carroll KM.

Am J Public Health. 2018 Nov;108(11):1535-1542. doi: 10.2105/AJPH.2018.304571. Epub 2018 Sep 25.


The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies.

Gibani MM, Voysey M, Jin C, Jones C, Thomaides-Brears H, Jones E, Baker P, Morgan M, Simmons A, Gordon MA, Cerundolo V, Pitzer VE, Angus B, Levine MM, Darton TC, Pollard AJ.

Clin Infect Dis. 2018 Sep 25. doi: 10.1093/cid/ciy670. [Epub ahead of print]


Reversal of Triple-Negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immunosuppression.

Rogers TJ, Christenson JL, Greene LI, O'Neill KI, Williams MM, Gordon MA, Nemkov T, D'Alessandro A, Degala GD, Shin J, Tan AC, Cittelly DM, Lambert JR, Richer JK.

Mol Cancer Res. 2018 Sep 13. doi: 10.1158/1541-7786.MCR-18-0246. [Epub ahead of print]


Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial.

Nachipo P, Hermann D, Quinnan G, Gordon MA, Van Voorhis WC, Iroh Tam PY.

Trials. 2018 Aug 23;19(1):456. doi: 10.1186/s13063-018-2846-6.


Typhoid conjugate vaccines: making vaccine history in Africa.

Meiring JE, Patel P, Patel P, Gordon MA.

Expert Rev Vaccines. 2018 Aug;17(8):673-676. doi: 10.1080/14760584.2018.1496825. Epub 2018 Jul 23. No abstract available.


Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a.

Pennington SH, Ferreira DM, Reiné J, Nyirenda TS, Thompson AL, Hancock CA, Wright AD, Gordon SB, Gordon MA.

Vaccine. 2018 Jul 25;36(31):4725-4733. doi: 10.1016/j.vaccine.2018.05.114. Epub 2018 Jun 27.


Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Napolitani G, Kurupati P, Teng KWW, Gibani MM, Rei M, Aulicino A, Preciado-Llanes L, Wong MT, Becht E, Howson L, de Haas P, Salio M, Blohmke CJ, Olsen LR, Pinto DMS, Scifo L, Jones C, Dobinson H, Campbell D, Juel HB, Thomaides-Brears H, Pickard D, Bumann D, Baker S, Dougan G, Simmons A, Gordon MA, Newell EW, Pollard AJ, Cerundolo V.

Nat Immunol. 2018 Jul;19(7):742-754. doi: 10.1038/s41590-018-0133-z. Epub 2018 Jun 20.


Using Concentration Curves to Assess Organization-Specific Relationships between Surgeon Volumes and Outcomes.

Kanter MH, Huang YC, Kally Z, Gordon MA, Meltzer C.

Jt Comm J Qual Patient Saf. 2018 Jun;44(6):321-327. doi: 10.1016/j.jcjq.2017.12.002. Epub 2018 Apr 16.


Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis.

Abdelgadir IS, Gordon MA, Akobeng AK.

Arch Dis Child. 2018 May 2. pii: archdischild-2017-314181. doi: 10.1136/archdischild-2017-314181. [Epub ahead of print]


Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella.

Hammarlöf DL, Kröger C, Owen SV, Canals R, Lacharme-Lora L, Wenner N, Schager AE, Wells TJ, Henderson IR, Wigley P, Hokamp K, Feasey NA, Gordon MA, Hinton JCD.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2614-E2623. doi: 10.1073/pnas.1714718115. Epub 2018 Feb 27.


Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia.

Nyirenda TS, Mandala WL, Gordon MA, Mastroeni P.

Microbes Infect. 2017 Dec 15. pii: S1286-4579(17)30221-6. doi: 10.1016/j.micinf.2017.11.014. [Epub ahead of print]


Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study.

Musicha P, Cornick JE, Bar-Zeev N, French N, Masesa C, Denis B, Kennedy N, Mallewa J, Gordon MA, Msefula CL, Heyderman RS, Everett DB, Feasey NA.

Lancet Infect Dis. 2017 Oct;17(10):1042-1052. doi: 10.1016/S1473-3099(17)30394-8. Epub 2017 Aug 14.


The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys.

Darton TC, Meiring JE, Tonks S, Khan MA, Khanam F, Shakya M, Thindwa D, Baker S, Basnyat B, Clemens JD, Dougan G, Dolecek C, Dunstan SJ, Gordon MA, Heyderman RS, Holt KE, Pitzer VE, Qadri F, Zaman K, Pollard AJ; STRATAA Study Consortium.

BMJ Open. 2017 Jul 2;7(6):e016283. doi: 10.1136/bmjopen-2017-016283.


Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children.

Nyirenda TS, Nyirenda JT, Tembo DL, Storm J, Dube Q, Msefula CL, Jambo KC, Mwandumba HC, Heyderman RS, Gordon MA, Mandala WL.

Clin Vaccine Immunol. 2017 Jul 5;24(7). pii: e00057-17. doi: 10.1128/CVI.00057-17. Print 2017 Jul.


Androgen Receptor Supports an Anchorage-Independent, Cancer Stem Cell-like Population in Triple-Negative Breast Cancer.

Barton VN, Christenson JL, Gordon MA, Greene LI, Rogers TJ, Butterfield K, Babbs B, Spoelstra NS, D'Amato NC, Elias A, Richer JK.

Cancer Res. 2017 Jul 1;77(13):3455-3466. doi: 10.1158/0008-5472.CAN-16-3240. Epub 2017 May 16.


Synergy between Androgen Receptor Antagonism and Inhibition of mTOR and HER2 in Breast Cancer.

Gordon MA, D'Amato NC, Gu H, Babbs B, Wulfkuhle J, Petricoin EF, Gallagher I, Dong T, Torkko K, Liu B, Elias A, Richer JK.

Mol Cancer Ther. 2017 Jul;16(7):1389-1400. doi: 10.1158/1535-7163.MCT-17-0111. Epub 2017 May 3.


Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings.

Feasey NA, Hadfield J, Keddy KH, Dallman TJ, Jacobs J, Deng X, Wigley P, Barquist L, Langridge GC, Feltwell T, Harris SR, Mather AE, Fookes M, Aslett M, Msefula C, Kariuki S, Maclennan CA, Onsare RS, Weill FX, Le Hello S, Smith AM, McClelland M, Desai P, Parry CM, Cheesbrough J, French N, Campos J, Chabalgoity JA, Betancor L, Hopkins KL, Nair S, Humphrey TJ, Lunguya O, Cogan TA, Tapia MD, Sow SO, Tennant SM, Bornstein K, Levine MM, Lacharme-Lora L, Everett DB, Kingsley RA, Parkhill J, Heyderman RS, Dougan G, Gordon MA, Thomson NR.

Nat Genet. 2017 Mar 30;49(4):651. doi: 10.1038/ng0417-651c. No abstract available.


Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1.

Owen SV, Wenner N, Canals R, Makumi A, Hammarlöf DL, Gordon MA, Aertsen A, Feasey NA, Hinton JC.

Front Microbiol. 2017 Feb 23;8:235. doi: 10.3389/fmicb.2017.00235. eCollection 2017.


Constitutive expression of microRNA-150 in mammary epithelium suppresses secretory activation and impairs de novo lipogenesis.

Heinz RE, Rudolph MC, Ramanathan P, Spoelstra NS, Butterfield KT, Webb PG, Babbs BL, Gao H, Chen S, Gordon MA, Anderson SM, Neville MC, Gu H, Richer JK.

Development. 2016 Nov 15;143(22):4236-4248. Epub 2016 Oct 11.


An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid.

Wong VK, Baker S, Connor TR, Pickard D, Page AJ, Dave J, Murphy N, Holliman R, Sefton A, Millar M, Dyson ZA, Dougan G, Holt KE; International Typhoid Consortium.

Nat Commun. 2016 Oct 5;7:12827. doi: 10.1038/ncomms12827.


Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa.

International Typhoid Consortium, Wong VK, Holt KE, Okoro C, Baker S, Pickard DJ, Marks F, Page AJ, Olanipekun G, Munir H, Alter R, Fey PD, Feasey NA, Weill FX, Le Hello S, Hart PJ, Kariuki S, Breiman RF, Gordon MA, Heyderman RS, Jacobs J, Lunguya O, Msefula C, MacLennan CA, Keddy KH, Smith AM, Onsare RS, De Pinna E, Nair S, Amos B, Dougan G, Obaro S.

PLoS Negl Trop Dis. 2016 Sep 22;10(9):e0004781. doi: 10.1371/journal.pntd.0004781. eCollection 2016 Sep.


Cooperative Dynamics of AR and ER Activity in Breast Cancer.

D'Amato NC, Gordon MA, Babbs B, Spoelstra NS, Carson Butterfield KT, Torkko KC, Phan VT, Barton VN, Rogers TJ, Sartorius CA, Elias A, Gertz J, Jacobsen BM, Richer JK.

Mol Cancer Res. 2016 Nov;14(11):1054-1067. Epub 2016 Aug 26.


Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings.

Feasey NA, Hadfield J, Keddy KH, Dallman TJ, Jacobs J, Deng X, Wigley P, Barquist L, Langridge GC, Feltwell T, Harris SR, Mather AE, Fookes M, Aslett M, Msefula C, Kariuki S, Maclennan CA, Onsare RS, Weill FX, Le Hello S, Smith AM, McClelland M, Desai P, Parry CM, Cheesbrough J, French N, Campos J, Chabalgoity JA, Betancor L, Hopkins KL, Nair S, Humphrey TJ, Lunguya O, Cogan TA, Tapia MD, Sow SO, Tennant SM, Bornstein K, Levine MM, Lacharme-Lora L, Everett DB, Kingsley RA, Parkhill J, Heyderman RS, Dougan G, Gordon MA, Thomson NR.

Nat Genet. 2016 Oct;48(10):1211-1217. doi: 10.1038/ng.3644. Epub 2016 Aug 22. Erratum in: Nat Genet. 2017 Mar 30;49(4):651.


Randomized Trial of Computerized Cognitive Behavioral Therapy for Alcohol Use Disorders: Efficacy as a Virtual Stand-Alone and Treatment Add-On Compared with Standard Outpatient Treatment.

Kiluk BD, Devore KA, Buck MB, Nich C, Frankforter TL, LaPaglia DM, Yates BT, Gordon MA, Carroll KM.

Alcohol Clin Exp Res. 2016 Sep;40(9):1991-2000. doi: 10.1111/acer.13162. Epub 2016 Aug 4.


Anti-androgen therapy in triple-negative breast cancer.

Barton VN, Gordon MA, Richer JK, Elias A.

Ther Adv Med Oncol. 2016 Jul;8(4):305-8. doi: 10.1177/1758834016646735. Epub 2016 May 31. No abstract available.


Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.

Pennington SH, Pojar S, Mitsi E, Gritzfeld JF, Nikolaou E, Solórzano C, Owugha JT, Masood Q, Gordon MA, Wright AD, Collins AM, Miyaji EN, Gordon SB, Ferreira DM.

Am J Respir Crit Care Med. 2016 Dec 15;194(12):1523-1531.


Prospective, Randomized Double-Blind Study: Does Decreasing Interscalene Nerve Block Volume for Surgical Anesthesia in Ambulatory Shoulder Surgery Offer Same-Day Patient Recovery Advantages?

Maalouf DB, Dorman SM, Sebeo J, Goytizolo EA, Gordon MA, Yadeau JT, Dehipawala SS, Fields K.

Reg Anesth Pain Med. 2016 Jul-Aug;41(4):438-44. doi: 10.1097/AAP.0000000000000418.


Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison.

Spoelstra NS, Cittelly DM, Christenson JL, Gordon MA, Elias A, Jedlicka P, Richer JK.

Hum Pathol. 2016 Oct;56:40-51. doi: 10.1016/j.humpath.2016.05.014. Epub 2016 May 31.


Perineural dexamethasone with subsartorial saphenous nerve blocks in ACL reconstruction.

Chisholm MF, Cheng J, Fields KG, Marx RG, Maalouf DB, Liguori GA, Gordon MA, Zayas VM, Yadeau JT.

Knee Surg Sports Traumatol Arthrosc. 2017 Apr;25(4):1298-1306. doi: 10.1007/s00167-016-4120-3. Epub 2016 Apr 13.


Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection.

Goh YS, Necchi F, O'Shaughnessy CM, Micoli F, Gavini M, Young SP, Msefula CL, Gondwe EN, Mandala WL, Gordon MA, Saul AJ, MacLennan CA.

PLoS Negl Trop Dis. 2016 Apr 8;10(4):e0004604. doi: 10.1371/journal.pntd.0004604. eCollection 2016 Apr.


Buprenorphine, Clonidine, Dexamethasone, and Ropivacaine for Interscalene Nerve Blockade: A Prospective, Randomized, Blinded, Ropivacaine Dose-Response Study.

YaDeau JT, Gordon MA, Goytizolo EA, Lin Y, Fields KG, Goon AK, Holck G, Miu TW, Gulotta LV, Dines DM, Craig EV.

Pain Med. 2016 May;17(5):940-60. doi: 10.1093/pm/pnv010. Epub 2015 Dec 14.


Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa.

Pennington SH, Thompson AL, Wright AK, Ferreira DM, Jambo KC, Wright AD, Faragher B, Gilmour JW, Gordon SB, Gordon MA.

J Infect Dis. 2016 Jun 1;213(11):1809-19. doi: 10.1093/infdis/jiw030. Epub 2016 Jan 24.


Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014.

Feasey NA, Masesa C, Jassi C, Faragher EB, Mallewa J, Mallewa M, MacLennan CA, Msefula C, Heyderman RS, Gordon MA.

Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S363-71. doi: 10.1093/cid/civ691.


Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi.

Pitzer VE, Feasey NA, Msefula C, Mallewa J, Kennedy N, Dube Q, Denis B, Gordon MA, Heyderman RS.

Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S251-8. doi: 10.1093/cid/civ710.


A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer.

D'Amato NC, Rogers TJ, Gordon MA, Greene LI, Cochrane DR, Spoelstra NS, Nemkov TG, D'Alessandro A, Hansen KC, Richer JK.

Cancer Res. 2015 Nov 1;75(21):4651-64. doi: 10.1158/0008-5472.CAN-15-2011. Epub 2015 Sep 11.


Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi.

Feasey NA, Everett D, Faragher EB, Roca-Feltrer A, Kang'ombe A, Denis B, Kerac M, Molyneux E, Molyneux M, Jahn A, Gordon MA, Heyderman RS.

PLoS Negl Trop Dis. 2015 Jul 31;9(7):e0003979. doi: 10.1371/journal.pntd.0003979. eCollection 2015.


Androgen Receptor Biology in Triple Negative Breast Cancer: a Case for Classification as AR+ or Quadruple Negative Disease.

Barton VN, D'Amato NC, Gordon MA, Christenson JL, Elias A, Richer JK.

Horm Cancer. 2015 Dec;6(5-6):206-13. doi: 10.1007/s12672-015-0232-3. Epub 2015 Jul 23. Review.


Epidemiology, Clinical Presentation, Laboratory Diagnosis, Antimicrobial Resistance, and Antimicrobial Management of Invasive Salmonella Infections.

Crump JA, Sjölund-Karlsson M, Gordon MA, Parry CM.

Clin Microbiol Rev. 2015 Oct;28(4):901-37. doi: 10.1128/CMR.00002-15. Review.


Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events.

Wong VK, Baker S, Pickard DJ, Parkhill J, Page AJ, Feasey NA, Kingsley RA, Thomson NR, Keane JA, Weill FX, Edwards DJ, Hawkey J, Harris SR, Mather AE, Cain AK, Hadfield J, Hart PJ, Thieu NT, Klemm EJ, Glinos DA, Breiman RF, Watson CH, Kariuki S, Gordon MA, Heyderman RS, Okoro C, Jacobs J, Lunguya O, Edmunds WJ, Msefula C, Chabalgoity JA, Kama M, Jenkins K, Dutta S, Marks F, Campos J, Thompson C, Obaro S, MacLennan CA, Dolecek C, Keddy KH, Smith AM, Parry CM, Karkey A, Mulholland EK, Campbell JI, Dongol S, Basnyat B, Dufour M, Bandaranayake D, Naseri TT, Singh SP, Hatta M, Newton P, Onsare RS, Isaia L, Dance D, Davong V, Thwaites G, Wijedoru L, Crump JA, De Pinna E, Nair S, Nilles EJ, Thanh DP, Turner P, Soeng S, Valcanis M, Powling J, Dimovski K, Hogg G, Farrar J, Holt KE, Dougan G.

Nat Genet. 2015 Jun;47(6):632-9. doi: 10.1038/ng.3281. Epub 2015 May 11.


Antimicrobial resistance and management of invasive Salmonella disease.

Kariuki S, Gordon MA, Feasey N, Parry CM.

Vaccine. 2015 Jun 19;33 Suppl 3:C21-9. doi: 10.1016/j.vaccine.2015.03.102. Epub 2015 Apr 23. Review.


Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

Feasey NA, Gaskell K, Wong V, Msefula C, Selemani G, Kumwenda S, Allain TJ, Mallewa J, Kennedy N, Bennett A, Nyirongo JO, Nyondo PA, Zulu MD, Parkhill J, Dougan G, Gordon MA, Heyderman RS.

PLoS Negl Trop Dis. 2015 Apr 24;9(4):e0003748. doi: 10.1371/journal.pntd.0003748. eCollection 2015 Apr.


Interprofessional Education: Finding a Place to Start.

Gordon MA, Lasater K, Brunett P, Dieckmann NF.

Nurse Educ. 2015 Sep-Oct;40(5):249-53. doi: 10.1097/NNE.0000000000000164.


Global burden of invasive nontyphoidal Salmonella disease, 2010(1).

Ao TT, Feasey NA, Gordon MA, Keddy KH, Angulo FJ, Crump JA.

Emerg Infect Dis. 2015 Jun;21(6). doi: 10.3201/eid2106.140999. Review.


Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo.

Barton VN, D'Amato NC, Gordon MA, Lind HT, Spoelstra NS, Babbs BL, Heinz RE, Elias A, Jedlicka P, Jacobsen BM, Richer JK.

Mol Cancer Ther. 2015 Mar;14(3):769-78. doi: 10.1158/1535-7163.MCT-14-0926. Epub 2015 Feb 23.


Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi.

Feasey NA, Cain AK, Msefula CL, Pickard D, Alaerts M, Aslett M, Everett DB, Allain TJ, Dougan G, Gordon MA, Heyderman RS, Kingsley RA.

Emerg Infect Dis. 2014 Nov;20(11):1957-9. doi: 10.3201/eid2011.141175. No abstract available.

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