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Probing the Virtual Proteome to Identify Novel Disease Biomarkers.

Mosley JD, Benson MD, Smith JG, Melander O, Ngo D, Shaffer CM, Ferguson JF, Herzig MS, McCarty CA, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Kitchner TE, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Kiryluk K, Mentch FD, Sleiman PM, Karlson EW, Verma SS, Zhu Y, Vasan RS, Yang Q, Denny JC, Roden DM, Gerszten RE, Wang TJ.

Circulation. 2018 Nov 27;138(22):2469-2481. doi: 10.1161/CIRCULATIONAHA.118.036063.


What Isn't a Case-Control Study?

Kicielinski KP, Dupépé EB, Gordon AS, Mayo NE, Walters BC.

Neurosurgery. 2018 Dec 13. doi: 10.1093/neuros/nyy591. [Epub ahead of print]


What is a Case-Control Study?

Dupépé EB, Kicielinski KP, Gordon AS, Walters BC.

Neurosurgery. 2018 Dec 10. doi: 10.1093/neuros/nyy590. [Epub ahead of print]


Absolute binding free energies for the SAMPL6 cucurbit[8]uril host-guest challenge via the AMOEBA polarizable force field.

Laury ML, Wang Z, Gordon AS, Ponder JW.

J Comput Aided Mol Des. 2018 Oct;32(10):1087-1095. doi: 10.1007/s10822-018-0147-5. Epub 2018 Oct 15.


The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype.

Stanaway IB, Hall TO, Rosenthal EA, Palmer M, Naranbhai V, Knevel R, Namjou-Khales B, Carroll RJ, Kiryluk K, Gordon AS, Linder J, Howell KM, Mapes BM, Lin FTJ, Joo YY, Hayes MG, Gharavi AG, Pendergrass SA, Ritchie MD, de Andrade M, Croteau-Chonka DC, Raychaudhuri S, Weiss ST, Lebo M, Amr SS, Carrell D, Larson EB, Chute CG, Rasmussen-Torvik LJ, Roy-Puckelwartz MJ, Sleiman P, Hakonarson H, Li R, Karlson EW, Peterson JF, Kullo IJ, Chisholm R, Denny JC, Jarvik GP; eMERGE Network, Crosslin DR.

Genet Epidemiol. 2019 Feb;43(1):63-81. doi: 10.1002/gepi.22167. Epub 2018 Oct 8.


A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.

Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM.

Nat Commun. 2018 Aug 30;9(1):3522. doi: 10.1038/s41467-018-05624-4.


Long-Term Outcomes in the Management of Central Neuropathic Pain Syndromes: A Prospective Observational Cohort Study.

Staudt MD, Clark AJ, Gordon AS, Lynch ME, Morley-Forster PK, Nathan H, Smyth C, Stitt LW, Toth C, Ware MA, Moulin DE.

Can J Neurol Sci. 2018 Sep;45(5):545-552. doi: 10.1017/cjn.2018.55. Epub 2018 Jul 12.


Voice and swallowing outcomes following reoperative anterior cervical discectomy and fusion with a 2-team surgical approach.

Erwood MS, Walters BC, Connolly TM, Gordon AS, Carroll WR, Agee BS, Carn BR, Hadley MN.

J Neurosurg Spine. 2018 Feb;28(2):140-148. doi: 10.3171/2017.5.SPINE161104. Epub 2017 Nov 24.


Decoding the neural representation of story meanings across languages.

Dehghani M, Boghrati R, Man K, Hoover J, Gimbel SI, Vaswani A, Zevin JD, Immordino-Yang MH, Gordon AS, Damasio A, Kaplan JT.

Hum Brain Mapp. 2017 Dec;38(12):6096-6106. doi: 10.1002/hbm.23814. Epub 2017 Sep 20.


Predicting elderly patient length of stay in hospital and community care using a series of conditional Coxian phase-type distributions, further conditioned on a survival tree.

Gordon AS, Marshall AH, Zenga M.

Health Care Manag Sci. 2018 Jun;21(2):269-280. doi: 10.1007/s10729-017-9411-9. Epub 2017 Jul 17.


Concordance between Research Sequencing and Clinical Pharmacogenetic Genotyping in the eMERGE-PGx Study.

Rasmussen-Torvik LJ, Almoguera B, Doheny KF, Freimuth RR, Gordon AS, Hakonarson H, Hawkins JB, Husami A, Ivacic LC, Kullo IJ, Linderman MD, Manolio TA, Obeng AO, Pellegrino R, Prows CA, Ritchie MD, Smith ME, Stallings SC, Wolf WA, Zhang K, Scott SA.

J Mol Diagn. 2017 Jul;19(4):561-566. doi: 10.1016/j.jmoldx.2017.04.002. Epub 2017 May 11.


Building a family network from genetic testing.

Leppig KA, Thiese HA, Carrel D, Crosslin DR, Dorschner MO, Gordon AS, Hartzler A, Ralston J, Scrol A, Larson EB, Jarvik GP.

Mol Genet Genomic Med. 2016 Dec 29;5(2):122-129. doi: 10.1002/mgg3.259. eCollection 2017 Mar.


Virtual Visits for Acute, Nonurgent Care: A Claims Analysis of Episode-Level Utilization.

Gordon AS, Adamson WC, DeVries AR.

J Med Internet Res. 2017 Feb 17;19(2):e35. doi: 10.2196/jmir.6783.


Long-Term Outcomes in the Management of Painful Diabetic Neuropathy.

Mai LM, Clark AJ, Gordon AS, Lynch ME, Morley-Forster PK, Nathan H, Smyth C, Stitt LW, Toth C, Ware MA, Moulin DE.

Can J Neurol Sci. 2017 Jul;44(4):337-342. doi: 10.1017/cjn.2016.429. Epub 2017 Jan 9.


The Effect of Educational Intervention Regarding the Knowledge of Mothers on Prevention of Accidents in Childhood.

Silva EC, Fernandes MN, Sá MC, Mota de Souza L, Gordon AS, Costa AC, Silva de Araújo T, Carvalho QG, Maia CC, Machado AL, Gubert Fdo A, Alexandrino da Silva L, Vieira NF.

Open Nurs J. 2016 Jul 29;10:113-21. doi: 10.2174/1874434601610010113. eCollection 2016.


A conditional approach for modelling patient readmissions to hospital using a mixture of Coxian phase-type distributions incorporating Bayes' theorem.

Gordon AS, Marshall AH, Cairns KJ.

Stat Med. 2016 Sep 20;35(21):3810-26. doi: 10.1002/sim.6953. Epub 2016 Apr 5.


Recurrent laryngeal nerve injury following reoperative anterior cervical discectomy and fusion: a meta-analysis.

Erwood MS, Hadley MN, Gordon AS, Carroll WR, Agee BS, Walters BC.

J Neurosurg Spine. 2016 Aug;25(2):198-204. doi: 10.3171/2015.9.SPINE15187. Epub 2016 Mar 25.


Using communication to manage uncertainty about cervical cancer screening guideline adherence among Appalachian women.

Cohen EL, Gordon AS, Record R, Shaunfield S, Jones GM, Collins T.

J Appl Commun Res. 2016;44(1):22-39. Epub 2016 Feb 18.


Researcher-library collaborations: Data repositories as a service for researchers.

Gordon AS, Millman DS, Steiger L, Adolph KE, Gilmore RO.

J Libr Sch Commun. 2015;3(2). pii: eP1238. Epub 2015 Sep 22.


Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network.

Bush WS, Crosslin DR, Owusu-Obeng A, Wallace J, Almoguera B, Basford MA, Bielinski SJ, Carrell DS, Connolly JJ, Crawford D, Doheny KF, Gallego CJ, Gordon AS, Keating B, Kirby J, Kitchner T, Manzi S, Mejia AR, Pan V, Perry CL, Peterson JF, Prows CA, Ralston J, Scott SA, Scrol A, Smith M, Stallings SC, Veldhuizen T, Wolf W, Volpi S, Wiley K, Li R, Manolio T, Bottinger E, Brilliant MH, Carey D, Chisholm RL, Chute CG, Haines JL, Hakonarson H, Harley JB, Holm IA, Kullo IJ, Jarvik GP, Larson EB, McCarty CA, Williams MS, Denny JC, Rasmussen-Torvik LJ, Roden DM, Ritchie MD.

Clin Pharmacol Ther. 2016 Aug;100(2):160-9. doi: 10.1002/cpt.350. Epub 2016 Jun 1.


Processing Narratives Concerning Protected Values: A Cross-Cultural Investigation of Neural Correlates.

Kaplan JT, Gimbel SI, Dehghani M, Immordino-Yang MH, Sagae K, Wong JD, Tipper CM, Damasio H, Gordon AS, Damasio A.

Cereb Cortex. 2017 Feb 1;27(2):1428-1438. doi: 10.1093/cercor/bhv325.


PGRNseq: a targeted capture sequencing panel for pharmacogenetic research and implementation.

Gordon AS, Fulton RS, Qin X, Mardis ER, Nickerson DA, Scherer S.

Pharmacogenet Genomics. 2016 Jan 5. [Epub ahead of print]


Prospective participant selection and ranking to maximize actionable pharmacogenetic variants and discovery in the eMERGE Network.

Crosslin DR, Robertson PD, Carrell DS, Gordon AS, Hanna DS, Burt A, Fullerton SM, Scrol A, Ralston J, Leppig K, Hartzler A, Baldwin E, Andrade Md, Kullo IJ, Tromp G, Doheny KF, Ritchie MD, Crane PK, Nickerson DA, Larson EB, Jarvik GP.

Genome Med. 2015 Jul 3;7(1):67. doi: 10.1186/s13073-015-0181-z. eCollection 2015.


Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.

Tabor HK, Auer PL, Jamal SM, Chong JX, Yu JH, Gordon AS, Graubert TA, O'Donnell CJ, Rich SS, Nickerson DA; NHLBI Exome Sequencing Project, Bamshad MJ.

Am J Hum Genet. 2014 Aug 7;95(2):183-93. doi: 10.1016/j.ajhg.2014.07.006. Epub 2014 Jul 31.


Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems.

Rasmussen-Torvik LJ, Stallings SC, Gordon AS, Almoguera B, Basford MA, Bielinski SJ, Brautbar A, Brilliant MH, Carrell DS, Connolly JJ, Crosslin DR, Doheny KF, Gallego CJ, Gottesman O, Kim DS, Leppig KA, Li R, Lin S, Manzi S, Mejia AR, Pacheco JA, Pan V, Pathak J, Perry CL, Peterson JF, Prows CA, Ralston J, Rasmussen LV, Ritchie MD, Sadhasivam S, Scott SA, Smith M, Vega A, Vinks AA, Volpi S, Wolf WA, Bottinger E, Chisholm RL, Chute CG, Haines JL, Harley JB, Keating B, Holm IA, Kullo IJ, Jarvik GP, Larson EB, Manolio T, McCarty CA, Nickerson DA, Scherer SE, Williams MS, Roden DM, Denny JC.

Clin Pharmacol Ther. 2014 Oct;96(4):482-9. doi: 10.1038/clpt.2014.137. Epub 2014 Jun 24.


Development, implementation and evaluation of a pain management and palliative care educational seminar for medical students.

Paneduro D, Pink LR, Smith AJ, Chakraborty A, Kirshen AJ, Backstein D, Woods NN, Gordon AS.

Pain Res Manag. 2014 Sep-Oct;19(5):230-4. Epub 2014 May 21.


Bihemispheric gunshot wounds: survival and long-term neuropsychological follow-up of three siblings.

Gordon AS, Tofil N, Marullo D, Blount JP.

Childs Nerv Syst. 2014 Sep;30(9):1589-94. doi: 10.1007/s00381-014-2429-0. Epub 2014 May 6.


Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project.

Kim DS, Crosslin DR, Auer PL, Suzuki SM, Marsillach J, Burt AA, Gordon AS, Meschia JF, Nalls MA, Worrall BB, Longstreth WT Jr, Gottesman RF, Furlong CE, Peters U, Rich SS, Nickerson DA, Jarvik GP; NHLBI Exome Sequencing Project.

J Lipid Res. 2014 Jun;55(6):1173-8. doi: 10.1194/jlr.P049247. Epub 2014 Apr 7.


Stroke experiences in weblogs: a feasibility study of sex differences.

Koh S, Gordon AS, Wienberg C, Sood SO, Morley S, Burke DM.

J Med Internet Res. 2014 Mar 19;16(3):e84. doi: 10.2196/jmir.2838.


Refining the structure and content of clinical genomic reports.

Dorschner MO, Amendola LM, Shirts BH, Kiedrowski L, Salama J, Gordon AS, Fullerton SM, Tarczy-Hornoch P, Byers PH, Jarvik GP.

Am J Med Genet C Semin Med Genet. 2014 Mar;166C(1):85-92. doi: 10.1002/ajmg.c.31395. Epub 2014 Mar 10.


Twins discordant for myositis and systemic lupus erythematosus show markedly enriched autoantibodies in the affected twin supporting environmental influences in pathogenesis.

Gan L, O'Hanlon TP, Gordon AS, Rider LG, Miller FW, Burbelo PD.

BMC Musculoskelet Disord. 2014 Mar 6;15:67. doi: 10.1186/1471-2474-15-67.


Music as a sleep aid in fibromyalgia.

Picard LM, Bartel LR, Gordon AS, Cepo D, Wu Q, Pink LR.

Pain Res Manag. 2014 Mar-Apr;19(2):97-101. Epub 2014 Feb 19.


Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset.

Gordon AS, Tabor HK, Johnson AD, Snively BM, Assimes TL, Auer PL, Ioannidis JP, Peters U, Robinson JG, Sucheston LE, Wang D, Sotoodehnia N, Rotter JI, Psaty BM, Jackson RD, Herrington DM, O'Donnell CJ, Reiner AP, Rich SS, Rieder MJ, Bamshad MJ, Nickerson DA; NHLBI GO Exome Sequencing Project.

Hum Mol Genet. 2014 Apr 15;23(8):1957-63. doi: 10.1093/hmg/ddt588. Epub 2013 Nov 26.


Exome sequencing reveals novel rare variants in the ryanodine receptor and calcium channel genes in malignant hyperthermia families.

Kim JH, Jarvik GP, Browning BL, Rajagopalan R, Gordon AS, Rieder MJ, Robertson PD, Nickerson DA, Fisher NA, Hopkins PM.

Anesthesiology. 2013 Nov;119(5):1054-65. doi: 10.1097/ALN.0b013e3182a8a998.


Prognostic relevance of cytochrome C oxidase in primary glioblastoma multiforme.

Griguer CE, Cantor AB, Fathallah-Shaykh HM, Gillespie GY, Gordon AS, Markert JM, Radovanovic I, Clement-Schatlo V, Shannon CN, Oliva CR.

PLoS One. 2013 Apr 10;8(4):e61035. doi: 10.1371/journal.pone.0061035. Print 2013.


Multidisciplinary staged surgical management of bifrontal meningoencephalocele with long-term follow-up.

Blount JP, Gordon AS, Foreman PM, Grant JH.

J Neurosurg Pediatr. 2013 Apr;11(4):478-84. doi: 10.3171/2012.11.PEDS12330. Epub 2013 Jan 25.


Reliability of postoperative photographs in assessment of facial nerve function after vestibular schwannoma resection.

Gordon AS, Westrick AC, Falola MI, Shannon CN, Walters BC, Fisher WS.

J Neurosurg. 2012 Nov;117(5):860-3. doi: 10.3171/2012.8.JNS12158. Epub 2012 Sep 7.


Intake assessment of problematic use of medications in a chronic noncancer pain clinic.

Pink LR, Smith AJ, Peng PW, Galonski MJ, Tumber PS, Evans D, Gourlay D, Gordon L, Bellingham G, Nijjar SS, Picard LM, Gordon AS.

Pain Res Manag. 2012 Jul-Aug;17(4):276-80.


Meningioma interdigitated with primary central nervous system B-cell lymphoma: A case report and literature review.

Gordon AS, Fallon KE, Riley KO.

Surg Neurol Int. 2011;2:181. doi: 10.4103/2152-7806.90716. Epub 2011 Dec 13.


Management of pediatric patients with pseudotumor cerebri.

Chern JJ, Tubbs RS, Gordon AS, Donnithorne KJ, Oakes WJ.

Childs Nerv Syst. 2012 Apr;28(4):575-8. doi: 10.1007/s00381-011-1657-9. Epub 2012 Jan 19.


Examination of migraine management in emergency departments.

Nijjar SS, Pink L, Gordon AS.

Pain Res Manag. 2011 May-Jun;16(3):183-6.


Intradural spinal endoscopy in children.

Chern JJ, Gordon AS, Naftel RP, Tubbs RS, Oakes WJ, Wellons JC 3rd.

J Neurosurg Pediatr. 2011 Jul;8(1):107-11. doi: 10.3171/2011.4.PEDS10533.


Preventing cerebrospinal fluid leak following transection of a tight filum terminale.

Chern JJ, Tubbs RS, Patel AJ, Gordon AS, Bandt SK, Smyth MD, Jea A, Oakes WJ.

J Neurosurg Pediatr. 2011 Jul;8(1):35-8. doi: 10.3171/2011.4.PEDS10502.


The Canadian STOP-PAIN project - Part 2: What is the cost of pain for patients on waitlists of multidisciplinary pain treatment facilities?

Guerriere DN, Choinière M, Dion D, Peng P, Stafford-Coyte E, Zagorski B, Banner R, Barton PM, Boulanger A, Clark AJ, Gordon AS, Guertin MC, Intrater HM, Lefort SM, Lynch ME, Moulin DE, Ong-Lam M, Racine M, Rashiq S, Shir Y, Taenzer P, Ware M.

Can J Anaesth. 2010 Jun;57(6):549-58. doi: 10.1007/s12630-010-9306-4. Epub 2010 Apr 23.


The Canadian STOP-PAIN project - Part 1: Who are the patients on the waitlists of multidisciplinary pain treatment facilities?

Choinière M, Dion D, Peng P, Banner R, Barton PM, Boulanger A, Clark AJ, Gordon AS, Guerriere DN, Guertin MC, Intrater HM, Lefort SM, Lynch ME, Moulin DE, Ong-Lam M, Racine M, Rashiq S, Shir Y, Taenzer P, Ware M.

Can J Anaesth. 2010 Jun;57(6):539-48. doi: 10.1007/s12630-010-9305-5.


Entry demographics and pharmacological treatment of migraine patients referred to a tertiary care pain clinic.

Nijjar SS, Gordon AS, Clark MD.

Cephalalgia. 2010 Jan;30(1):87-91. doi: 10.1111/j.1468-2982.2009.01900.x.


Adaptations to climate in candidate genes for common metabolic disorders.

Hancock AM, Witonsky DB, Gordon AS, Eshel G, Pritchard JK, Coop G, Di Rienzo A.

PLoS Genet. 2008 Feb;4(2):e32. doi: 10.1371/journal.pgen.0040032.


Characterization of Pfiesteria ichthyocidal activity.

Gordon AS, Marshall HG, Shumway SE, Coyne KJ, Lewitus AJ, Mallin MA, Rublee PA.

Appl Environ Microbiol. 2005 Oct;71(10):6463; author reply 6464. No abstract available.


Demonstration of toxicity to fish and to mammalian cells by Pfiesteria species: comparison of assay methods and strains.

Burkholder JM, Gordon AS, Moeller PD, Law JM, Coyne KJ, Lewitus AJ, Ramsdell JS, Marshall HG, Deamer NJ, Cary SC, Kempton JW, Morton SL, Rublee PA.

Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3471-6. Epub 2005 Feb 22.


Ethanol operant self-administration in rats is regulated by adenosine A2 receptors.

Arolfo MP, Yao L, Gordon AS, Diamond I, Janak PH.

Alcohol Clin Exp Res. 2004 Sep;28(9):1308-16.


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