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Items: 36

1.

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS.

McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D.

Elife. 2019 Sep 3;8. pii: e48847. doi: 10.7554/eLife.48847.

2.

Nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh class B cirrhosis: Safety and clinical outcomes in a retrospective case series.

Kambhampati S, Bauer KE, Bracci PM, Keenan BP, Behr SC, Gordan JD, Kelley RK.

Cancer. 2019 Sep 15;125(18):3234-3241. doi: 10.1002/cncr.32206. Epub 2019 Jun 2.

PMID:
31154669
3.

KRASG12C inhibition produces a driver-limited state revealing collateral dependencies.

Lou K, Steri V, Ge AY, Hwang YC, Yogodzinski CH, Shkedi AR, Choi ALM, Mitchell DC, Swaney DL, Hann B, Gordan JD, Shokat KM, Gilbert LA.

Sci Signal. 2019 May 28;12(583). pii: eaaw9450. doi: 10.1126/scisignal.aaw9450.

4.

Road map for fibrolamellar carcinoma: progress and goals of a diversified approach.

Kastenhuber ER, Craig J, Ramsey J, Sullivan KM, Sage J, de Oliveira S, Riehle KJ, Scott JD, Gordan JD, Bardeesy N, Abou-Alfa GK.

J Hepatocell Carcinoma. 2019 Jan 31;6:41-48. doi: 10.2147/JHC.S194764. eCollection 2019.

5.

Translation control of the immune checkpoint in cancer and its therapeutic targeting.

Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, Worland ST, Asthana S, Barna M, Webster KR, Cunningham JT, Ruggero D.

Nat Med. 2019 Feb;25(2):301-311. doi: 10.1038/s41591-018-0321-2. Epub 2019 Jan 14.

6.

Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation.

Frazier NM, Brand T, Gordan JD, Grandis J, Jura N.

Oncogene. 2019 Mar;38(11):1936-1950. doi: 10.1038/s41388-018-0537-0. Epub 2018 Nov 2.

7.

Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma.

Song X, Liu X, Wang H, Wang J, Qiao Y, Cigliano A, Utpatel K, Ribback S, Pilo MG, Serra M, Gordan JD, Che L, Zhang S, Cossu A, Porcu A, Pascale RM, Dombrowski F, Hu H, Calvisi DF, Evert M, Chen X.

Clin Cancer Res. 2019 Jan 1;25(1):403-413. doi: 10.1158/1078-0432.CCR-18-0284. Epub 2018 Jul 3.

PMID:
30084835
8.

Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer.

Donnella HJ, Webber JT, Levin RS, Camarda R, Momcilovic O, Bayani N, Shah KN, Korkola JE, Shokat KM, Goga A, Gordan JD, Bandyopadhyay S.

Nat Chem Biol. 2018 Aug;14(8):768-777. doi: 10.1038/s41589-018-0081-9. Epub 2018 Jun 25.

9.

Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion.

Lim HC, Montesion M, Botton T, Collisson EA, Umetsu SE, Behr SC, Gordan JD, Stephens PJ, Kelley RK.

Oncologist. 2018 Sep;23(9):998-1003. doi: 10.1634/theoncologist.2017-0645. Epub 2018 Apr 5.

10.

Sampling strategies to capture single-cell heterogeneity.

Rajaram S, Heinrich LE, Gordan JD, Avva J, Bonness KM, Witkiewicz AK, Malter JS, Atreya CE, Warren RS, Wu LF, Altschuler SJ.

Nat Methods. 2017 Oct;14(10):967-970. doi: 10.1038/nmeth.4427. Epub 2017 Sep 4.

11.

An Optimized Chromatographic Strategy for Multiplexing In Parallel Reaction Monitoring Mass Spectrometry: Insights from Quantitation of Activated Kinases.

Urisman A, Levin RS, Gordan JD, Webber JT, Hernandez H, Ishihama Y, Shokat KM, Burlingame AL.

Mol Cell Proteomics. 2017 Feb;16(2):265-277. doi: 10.1074/mcp.M116.058172. Epub 2016 Dec 11.

12.

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib.

Miller RE, Brough R, Bajrami I, Williamson CT, McDade S, Campbell J, Kigozi A, Rafiq R, Pemberton H, Natrajan R, Joel J, Astley H, Mahoney C, Moore JD, Torrance C, Gordan JD, Webber JT, Levin RS, Shokat KM, Bandyopadhyay S, Lord CJ, Ashworth A.

Mol Cancer Ther. 2016 Jul;15(7):1472-84. doi: 10.1158/1535-7163.MCT-15-0554. Epub 2016 Jun 30.

13.

Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma.

Saha SK, Gordan JD, Kleinstiver BP, Vu P, Najem MS, Yeo JC, Shi L, Kato Y, Levin RS, Webber JT, Damon LJ, Egan RK, Greninger P, McDermott U, Garnett MJ, Jenkins RL, Rieger-Christ KM, Sullivan TB, Hezel AF, Liss AS, Mizukami Y, Goyal L, Ferrone CR, Zhu AX, Joung JK, Shokat KM, Benes CH, Bardeesy N.

Cancer Discov. 2016 Jul;6(7):727-39. doi: 10.1158/2159-8290.CD-15-1442. Epub 2016 May 26.

14.

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.

Evason KJ, Francisco MT, Juric V, Balakrishnan S, Lopez Pazmino Mdel P, Gordan JD, Kakar S, Spitsbergen J, Goga A, Stainier DY.

PLoS Genet. 2015 Jul 2;11(7):e1005305. doi: 10.1371/journal.pgen.1005305. eCollection 2015 Jul.

15.

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakhshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S.

Cancer Discov. 2015 Feb;5(2):154-67. doi: 10.1158/2159-8290.CD-14-0552. Epub 2014 Dec 12. Erratum in: Cancer Discov. 2018 Aug;8(8):1045. Rakshandehroo, Taha [corrected to Rakhshandehroo, Taha].

16.

Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors.

Sos ML, Levin RS, Gordan JD, Oses-Prieto JA, Webber JT, Salt M, Hann B, Burlingame AL, McCormick F, Bandyopadhyay S, Shokat KM.

Cell Rep. 2014 Aug 21;8(4):1037-48. doi: 10.1016/j.celrep.2014.07.010. Epub 2014 Aug 7.

17.

Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets.

Dondeti VR, Wubbenhorst B, Lal P, Gordan JD, D'Andrea K, Attiyeh EF, Simon MC, Nathanson KL.

Cancer Res. 2012 Jan 1;72(1):112-21. doi: 10.1158/0008-5472.CAN-11-1698. Epub 2011 Nov 17.

18.

"And what other medications are you taking?".

Gordan JD, Chay WY, Kelley RK, Ko AH, Choo SP, Venook AP.

J Clin Oncol. 2011 Apr 10;29(11):e288-91. doi: 10.1200/JCO.2010.32.8054. Epub 2011 Jan 18. No abstract available.

PMID:
21245436
19.

HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses.

Bertout JA, Majmundar AJ, Gordan JD, Lam JC, Ditsworth D, Keith B, Brown EJ, Nathanson KL, Simon MC.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14391-6. doi: 10.1073/pnas.0907357106. Epub 2009 Aug 12.

20.

Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma.

Wright TM, Brannon AR, Gordan JD, Mikels AJ, Mitchell C, Chen S, Espinosa I, van de Rijn M, Pruthi R, Wallen E, Edwards L, Nusse R, Rathmell WK.

Oncogene. 2009 Jul 9;28(27):2513-23. doi: 10.1038/onc.2009.116. Epub 2009 May 18.

21.

HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma.

Gordan JD, Lal P, Dondeti VR, Letrero R, Parekh KN, Oquendo CE, Greenberg RA, Flaherty KT, Rathmell WK, Keith B, Simon MC, Nathanson KL.

Cancer Cell. 2008 Dec 9;14(6):435-46. doi: 10.1016/j.ccr.2008.10.016.

22.

Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism.

Young RM, Wang SJ, Gordan JD, Ji X, Liebhaber SA, Simon MC.

J Biol Chem. 2008 Jun 13;283(24):16309-19. doi: 10.1074/jbc.M710079200. Epub 2008 Apr 22.

23.

HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation.

Gordan JD, Thompson CB, Simon MC.

Cancer Cell. 2007 Aug;12(2):108-13. Review.

24.

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.

Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB.

Genes Dev. 2007 May 1;21(9):1037-49. Epub 2007 Apr 16.

25.

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC.

Cancer Cell. 2007 Apr;11(4):335-47.

26.

Hypoxia-inducible factors: central regulators of the tumor phenotype.

Gordan JD, Simon MC.

Curr Opin Genet Dev. 2007 Feb;17(1):71-7. Epub 2007 Jan 8. Review.

27.

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest.

Zhang F, Hamanaka RB, Bobrovnikova-Marjon E, Gordan JD, Dai MS, Lu H, Simon MC, Diehl JA.

J Biol Chem. 2006 Oct 6;281(40):30036-45. Epub 2006 Aug 7.

28.

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B.

Genes Dev. 2006 Mar 1;20(5):557-70.

29.

ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation.

Wang H, McCann FE, Gordan JD, Wu X, Raab M, Malik TH, Davis DM, Rudd CE.

J Exp Med. 2004 Oct 18;200(8):1063-74. Epub 2004 Oct 11.

30.
31.

Universal tumor antigens as targets for immunotherapy.

Gordan JD, Vonderheide RH.

Cytotherapy. 2002;4(4):317-27. Review.

PMID:
12396831
32.

Antigens recognized by autologous antibody in patients with renal-cell carcinoma.

Scanlan MJ, Gordan JD, Williamson B, Stockert E, Bander NH, Jongeneel V, Gure AO, Jäger D, Jäger E, Knuth A, Chen YT, Old LJ.

Int J Cancer. 1999 Nov 12;83(4):456-64.

33.

Isoforms of the human PDZ-73 protein exhibit differential tissue expression.

Scanlan MJ, Williamson B, Jungbluth A, Stockert E, Arden KC, Viars CS, Gure AO, Gordan JD, Chen YT, Old LJ.

Biochim Biophys Acta. 1999 Apr 14;1445(1):39-52.

PMID:
10209257
34.

Characterization of human colon cancer antigens recognized by autologous antibodies.

Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, Türeci O, Sahin U, Pfreundschuh M, Old LJ.

Int J Cancer. 1998 May 29;76(5):652-8.

35.

Mathematical exploration of pulsatility in cultured gonadotropin-releasing hormone neurons.

Gordan JD, Attardi BJ, Pfaff DW.

Neuroendocrinology. 1998 Jan;67(1):2-17.

PMID:
9485164
36.

Reproductive functions illustrating direct and indirect effects of genes on behavior.

Ogawa S, Gordan JD, Taylor J, Lubahn D, Korach K, Pfaff DW.

Horm Behav. 1996 Dec;30(4):487-94.

PMID:
9047273

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