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Items: 5


Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2.

Stauft CB, Song Y, Gorbatsevych O, Pantoja P, Rodriguez IV, Futcher B, Sariol CA, Wimmer E.

Virology. 2019 Sep 5;537:237-245. doi: 10.1016/j.virol.2019.09.003. [Epub ahead of print]


Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes.

Stauft CB, Shen SH, Song Y, Gorbatsevych O, Asare E, Futcher B, Mueller S, Payne A, Brecher M, Kramer L, Wimmer E.

PLoS One. 2018 Sep 7;13(9):e0198303. doi: 10.1371/journal.pone.0198303. eCollection 2018.


Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes.

Song Y, Gorbatsevych O, Liu Y, Mugavero J, Shen SH, Ward CB, Asare E, Jiang P, Paul AV, Mueller S, Wimmer E.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8731-E8740. doi: 10.1073/pnas.1714385114. Epub 2017 Sep 25.


Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished.

Futcher B, Gorbatsevych O, Shen SH, Stauft CB, Song Y, Wang B, Leatherwood J, Gardin J, Yurovsky A, Mueller S, Wimmer E.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3635-6. doi: 10.1073/pnas.1507710112. Epub 2015 Jun 12. No abstract available.


Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference.

Shen SH, Stauft CB, Gorbatsevych O, Song Y, Ward CB, Yurovsky A, Mueller S, Futcher B, Wimmer E.

Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4749-54. doi: 10.1073/pnas.1502864112. Epub 2015 Mar 30.

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