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Items: 17


Localization of Outer Membrane Proteins in Treponema denticola by Quantitative Proteome Analyses of Outer Membrane Vesicles and Cellular Fractions.

Veith PD, Glew MD, Gorasia DG, Chen D, O'Brien-Simpson NM, Reynolds EC.

J Proteome Res. 2019 Apr 5;18(4):1567-1581. doi: 10.1021/acs.jproteome.8b00860. Epub 2019 Feb 26.


Porphyromonas gingivalis Gingipains Display Transpeptidation Activity.

Zhang L, Veith PD, Huq NL, Chen YY, Seers CA, Cross KJ, Gorasia DG, Reynolds EC.

J Proteome Res. 2018 Aug 3;17(8):2803-2818. doi: 10.1021/acs.jproteome.8b00286. Epub 2018 Jul 20.


PorV is an Outer Membrane Shuttle Protein for the Type IX Secretion System.

Glew MD, Veith PD, Chen D, Gorasia DG, Peng B, Reynolds EC.

Sci Rep. 2017 Aug 18;7(1):8790. doi: 10.1038/s41598-017-09412-w.


Type IX secretion: the generation of bacterial cell surface coatings involved in virulence, gliding motility and the degradation of complex biopolymers.

Veith PD, Glew MD, Gorasia DG, Reynolds EC.

Mol Microbiol. 2017 Oct;106(1):35-53. doi: 10.1111/mmi.13752. Epub 2017 Aug 9. Review.


Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System.

Gorasia DG, Veith PD, Hanssen EG, Glew MD, Sato K, Yukitake H, Nakayama K, Reynolds EC.

PLoS Pathog. 2016 Aug 10;12(8):e1005820. doi: 10.1371/journal.ppat.1005820. eCollection 2016 Aug.


A prominent role of PDIA6 in processing of misfolded proinsulin.

Gorasia DG, Dudek NL, Safavi-Hemami H, Perez RA, Schittenhelm RB, Saunders PM, Wee S, Mangum JE, Hubbard MJ, Purcell AW.

Biochim Biophys Acta. 2016 Jun;1864(6):715-723. doi: 10.1016/j.bbapap.2016.03.002. Epub 2016 Mar 3.


Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like Mechanism.

Gorasia DG, Veith PD, Chen D, Seers CA, Mitchell HA, Chen YY, Glew MD, Dashper SG, Reynolds EC.

PLoS Pathog. 2015 Sep 4;11(9):e1005152. doi: 10.1371/journal.ppat.1005152. eCollection 2015 Sep.


Pancreatic beta cells are highly susceptible to oxidative and ER stresses during the development of diabetes.

Gorasia DG, Dudek NL, Veith PD, Shankar R, Safavi-Hemami H, Williamson NA, Reynolds EC, Hubbard MJ, Purcell AW.

J Proteome Res. 2015 Feb 6;14(2):688-99. doi: 10.1021/pr500643h. Epub 2014 Dec 8.


Porphyromonas gingivalis outer membrane vesicles exclusively contain outer membrane and periplasmic proteins and carry a cargo enriched with virulence factors.

Veith PD, Chen YY, Gorasia DG, Chen D, Glew MD, O'Brien-Simpson NM, Cecil JD, Holden JA, Reynolds EC.

J Proteome Res. 2014 May 2;13(5):2420-32. doi: 10.1021/pr401227e. Epub 2014 Apr 3.


Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization.

Safavi-Hemami H, Hu H, Gorasia DG, Bandyopadhyay PK, Veith PD, Young ND, Reynolds EC, Yandell M, Olivera BM, Purcell AW.

Mol Cell Proteomics. 2014 Apr;13(4):938-53. doi: 10.1074/mcp.M113.031351. Epub 2014 Jan 29.


Protein substrates of a novel secretion system are numerous in the Bacteroidetes phylum and have in common a cleavable C-terminal secretion signal, extensive post-translational modification, and cell-surface attachment.

Veith PD, Nor Muhammad NA, Dashper SG, Likić VA, Gorasia DG, Chen D, Byrne SJ, Catmull DV, Reynolds EC.

J Proteome Res. 2013 Oct 4;12(10):4449-61. doi: 10.1021/pr400487b. Epub 2013 Sep 23.


Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails.

Safavi-Hemami H, Gorasia DG, Steiner AM, Williamson NA, Karas JA, Gajewiak J, Olivera BM, Bulaj G, Purcell AW.

J Biol Chem. 2012 Oct 5;287(41):34288-303. doi: 10.1074/jbc.M112.366781. Epub 2012 Aug 13.


Constitutive and inflammatory immunopeptidome of pancreatic β-cells.

Dudek NL, Tan CT, Gorasia DG, Croft NP, Illing PT, Purcell AW.

Diabetes. 2012 Nov;61(11):3018-25. doi: 10.2337/db11-1333. Epub 2012 Aug 7.


PG0026 is the C-terminal signal peptidase of a novel secretion system of Porphyromonas gingivalis.

Glew MD, Veith PD, Peng B, Chen YY, Gorasia DG, Yang Q, Slakeski N, Chen D, Moore C, Crawford S, Reynolds EC.

J Biol Chem. 2012 Jul 13;287(29):24605-17. doi: 10.1074/jbc.M112.369223. Epub 2012 May 16.


Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands.

Scull KE, Dudek NL, Corbett AJ, Ramarathinam SH, Gorasia DG, Williamson NA, Purcell AW.

Mol Immunol. 2012 Jun;51(2):136-42. doi: 10.1016/j.molimm.2012.02.117. Epub 2012 Mar 17.


Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway.

Safavi-Hemami H, Siero WA, Gorasia DG, Young ND, Macmillan D, Williamson NA, Purcell AW.

J Proteome Res. 2011 Sep 2;10(9):3904-19. doi: 10.1021/pr1012976. Epub 2011 Aug 11.


Experimental autoimmune encephalomyelitis (EAE) IN C57Bl/6 mice is not associated with astrogliosis.

Pham H, Doerrbecker J, Ramp AA, D'Souza CS, Gorasia DG, Purcell AW, Ayers MM, Orian JM.

J Neuroimmunol. 2011 Mar;232(1-2):51-62. doi: 10.1016/j.jneuroim.2010.10.006. Epub 2010 Nov 6.


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