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Items: 1 to 50 of 106

1.

Stability indicating liquid chromatographic method for simultaneous quantification of betamethasone valerate and tazarotene in in-vitro and ex-vivo studies of complex nanoformulation.

Rapalli VK, Singhvi G, Gorantla S, Waghule T, Dubey SK, Saha RN, Hasnain MS, Nayak AK.

J Sep Sci. 2019 Sep 17. doi: 10.1002/jssc.201900538. [Epub ahead of print]

PMID:
31529758
2.

Phosphorylation of Beclin-1 by BCR-ABL suppresses autophagy in chronic myeloid leukemia.

Yu C, Gorantla SP, Müller-Rudorf A, Müller TA, Kreutmair S, Albers C, Jakob L, Lippert LJ, Yue Z, Engelhardt M, Follo M, Zeiser R, Huber TB, Duyster J, Illert AL.

Haematologica. 2019 Aug 8. pii: haematol.2018.212027. doi: 10.3324/haematol.2018.212027. [Epub ahead of print]

3.

Eluted 25-hydroxyvitamin D3 from radially aligned nanofiber scaffolds enhances cathelicidin production while reducing inflammatory response in human immune system-engrafted mice.

Chen S, Ge L, Wang H, Cheng Y, Gorantla S, Poluektova LY, Gombart AF, Xie J.

Acta Biomater. 2019 Aug 3. pii: S1742-7061(19)30552-5. doi: 10.1016/j.actbio.2019.08.005. [Epub ahead of print]

PMID:
31386930
4.

UV Spectrophotometric method for characterization of curcumin loaded nanostructured lipid nanocarriers in simulated conditions: Method development, in-vitro and ex-vivo applications in topical delivery.

Rapalli VK, Kaul V, Gorantla S, Waghule T, Dubey SK, Pandey MM, Singhvi G.

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jul 15;224:117392. doi: 10.1016/j.saa.2019.117392. [Epub ahead of print]

PMID:
31330421
5.

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.

Dash PK, Kaminski R, Bella R, Su H, Mathews S, Ahooyi TM, Chen C, Mancuso P, Sariyer R, Ferrante P, Donadoni M, Robinson JA, Sillman B, Lin Z, Hilaire JR, Banoub M, Elango M, Gautam N, Mosley RL, Poluektova LY, McMillan J, Bade AN, Gorantla S, Sariyer IK, Burdo TH, Young WB, Amini S, Gordon J, Jacobson JM, Edagwa B, Khalili K, Gendelman HE.

Nat Commun. 2019 Jul 2;10(1):2753. doi: 10.1038/s41467-019-10366-y.

6.

Current Epidemiology of Vocal Cord Dysfunction After Congenital Heart Surgery in Young Infants.

Gorantla SC, Chan T, Shen I, Wilkes J, Bratton SL.

Pediatr Crit Care Med. 2019 Sep;20(9):817-825. doi: 10.1097/PCC.0000000000002010.

PMID:
31246739
7.

Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells.

Vengoji R, Macha MA, Nimmakayala RK, Rachagani S, Siddiqui JA, Mallya K, Gorantla S, Jain M, Ponnusamy MP, Batra SK, Shonka N.

J Exp Clin Cancer Res. 2019 Jun 18;38(1):266. doi: 10.1186/s13046-019-1264-2.

8.

NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia.

Rudorf A, Müller TA, Klingeberg C, Kreutmair S, Poggio T, Gorantla SP, Rückert T, Schmitt-Graeff A, Gengenbacher A, Paschka P, Baldus C, Zeiser R, Vassiliou GS, Bradley A, Duyster J, Illert AL.

Blood. 2019 Jul 25;134(4):383-388. doi: 10.1182/blood.2018883140. Epub 2019 Jun 11.

9.

Small molecule ONC201 inhibits HIV-1 replication in macrophages via FOXO3a and TRAIL.

Zhao R, Li Y, Gorantla S, Poluektova LY, Lin H, Gao F, Wang H, Zhao J, Zheng JC, Huang Y.

Antiviral Res. 2019 Aug;168:134-145. doi: 10.1016/j.antiviral.2019.05.015. Epub 2019 May 31.

10.

Introduction of an undergraduate interprofessional simulation based skills training program in obstetrics and gynaecology in India.

Gorantla S, Bansal U, Singh JV, Dwivedi AD, Malhotra A, Kumar A.

Adv Simul (Lond). 2019 Apr 18;4:6. doi: 10.1186/s41077-019-0096-7. eCollection 2019.

11.

Immune Activations and Viral Tissue Compartmentalization During Progressive HIV-1 Infection of Humanized Mice.

Su H, Cheng Y, Sravanam S, Mathews S, Gorantla S, Poluektova LY, Dash PK, Gendelman HE.

Front Immunol. 2019 Feb 28;10:340. doi: 10.3389/fimmu.2019.00340. eCollection 2019.

12.

Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice.

Mathews S, Branch Woods A, Katano I, Makarov E, Thomas MB, Gendelman HE, Poluektova LY, Ito M, Gorantla S.

Mol Neurodegener. 2019 Mar 5;14(1):12. doi: 10.1186/s13024-019-0311-y.

13.

Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages.

Saminathan P, Kevadiya BD, Marker DF, Gendelman HE, Gorantla S, Gelbard HA.

J Neuroimmune Pharmacol. 2019 Mar;14(1):44-51. doi: 10.1007/s11481-018-09829-8. Epub 2019 Jan 7. Review.

PMID:
30617749
14.

Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection.

Dagur RS, Branch-Woods A, Mathews S, Joshi PS, Quadros RM, Harms DW, Cheng Y, Miles SM, Pirruccello SJ, Gurumurthy CB, Gorantla S, Poluektova LY.

BMC Immunol. 2019 Jan 7;20(1):2. doi: 10.1186/s12865-018-0279-3.

15.

Neurotheranostics as personalized medicines.

Kevadiya BD, Ottemann BM, Thomas MB, Mukadam I, Nigam S, McMillan J, Gorantla S, Bronich TK, Edagwa B, Gendelman HE.

Adv Drug Deliv Rev. 2018 Oct 26. pii: S0169-409X(18)30261-8. doi: 10.1016/j.addr.2018.10.011. [Epub ahead of print] Review.

16.

Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine.

López OV, Gorantla S, Segarra AC, Andino Norat MC, Álvarez M, Skolasky RL, Meléndez LM.

J Neuroimmune Pharmacol. 2019 Jun;14(2):226-240. doi: 10.1007/s11481-018-9807-4. Epub 2018 Oct 10.

17.

Modulating cellular autophagy for controlled antiretroviral drug release.

Thomas MB, Gnanadhas DP, Dash PK, Machhi J, Lin Z, McMillan J, Edagwa B, Gelbard H, Gendelman HE, Gorantla S.

Nanomedicine (Lond). 2018 Sep;13(17):2139-2154. doi: 10.2217/nnm-2018-0224. Epub 2018 Aug 21.

18.

Preliminary Studies on Immune Response and Viral Pathogenesis of Zika Virus in Rhesus Macaques.

Woollard SM, Olwenyi OA, Dutta D, Dave RS, Mathews S, Gorantla S, Johnson N, Giavedoni L, Norgren RB Jr, Byrareddy SN.

Pathogens. 2018 Aug 20;7(3). pii: E70. doi: 10.3390/pathogens7030070.

19.

The Metabolism of Separase Inhibitor Sepin-1 in Human, Mouse, and Rat Liver Microsomes.

Li F, Zhang N, Gorantla S, Gilbertson SR, Pati D.

Front Pharmacol. 2018 May 7;9:313. doi: 10.3389/fphar.2018.00313. eCollection 2018.

20.

Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice.

McMillan JM, Cobb DA, Lin Z, Banoub MG, Dagur RS, Branch Woods AA, Wang W, Makarov E, Kocher T, Joshi PS, Quadros RM, Harms DW, Cohen SM, Gendelman HE, Gurumurthy CB, Gorantla S, Poluektova LY.

J Pharmacol Exp Ther. 2018 May;365(2):272-280. doi: 10.1124/jpet.117.247288. Epub 2018 Feb 23.

21.

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

Prestipino A, Emhardt AJ, Aumann K, O'Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M, Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R.

Sci Transl Med. 2018 Feb 21;10(429). pii: eaam7729. doi: 10.1126/scitranslmed.aam7729.

22.

Creation of a long-acting nanoformulated dolutegravir.

Sillman B, Bade AN, Dash PK, Bhargavan B, Kocher T, Mathews S, Su H, Kanmogne GD, Poluektova LY, Gorantla S, McMillan J, Gautam N, Alnouti Y, Edagwa B, Gendelman HE.

Nat Commun. 2018 Feb 6;9(1):443. doi: 10.1038/s41467-018-02885-x.

23.

Improving carrier transport in Cu2O thin films by rapid thermal annealing.

Bergum K, Riise HN, Gorantla S, Lindberg PF, Jensen IJT, Gunnæs AE, Galeckas A, Diplas S, Svensson BG, Monakhov E.

J Phys Condens Matter. 2018 Jan 24;30(7):075702. doi: 10.1088/1361-648X/aaa5f4. [Epub ahead of print]

PMID:
29363624
24.

Human hepatocyte depletion in the presence of HIV-1 infection in dual reconstituted humanized mice.

Dagur RS, Wang W, Cheng Y, Makarov E, Ganesan M, Suemizu H, Gebhart CL, Gorantla S, Osna N, Poluektova LY.

Biol Open. 2018 Feb 13;7(2). pii: bio029785. doi: 10.1242/bio.029785.

25.

Improving carrier transport in Cu<sub>2</sub>O thin films by rapid thermal annealing.

Bergum K, Riise HN, Gorantla S, Lindberg P, Jensen IJT, Gunnaes A, Galeckas A, Diplas S, Svensson B, Monakhov E.

J Phys Condens Matter. 2018 Jan 8. doi: 10.1088/1361-648X/aaa5f4. [Epub ahead of print]

PMID:
29309278
26.

PD-L1, inflammation, non-coding RNAs, and neuroblastoma: Immuno-oncology perspective.

Nallasamy P, Chava S, Verma SS, Mishra S, Gorantla S, Coulter DW, Byrareddy SN, Batra SK, Gupta SC, Challagundla KB.

Semin Cancer Biol. 2018 Oct;52(Pt 2):53-65. doi: 10.1016/j.semcancer.2017.11.009. Epub 2017 Nov 28. Review.

PMID:
29196189
27.

Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains.

Li W, Gorantla S, Gendelman HE, Poluektova LY.

Dis Model Mech. 2017 Dec 19;10(12):1489-1502. doi: 10.1242/dmm.031773.

28.

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles.

Zhou T, Su H, Dash P, Lin Z, Dyavar Shetty BL, Kocher T, Szlachetka A, Lamberty B, Fox HS, Poluektova L, Gorantla S, McMillan J, Gautam N, Mosley RL, Alnouti Y, Edagwa B, Gendelman HE.

Biomaterials. 2018 Jan;151:53-65. doi: 10.1016/j.biomaterials.2017.10.023. Epub 2017 Oct 15.

29.

Sonic Hedgehog mimetic prevents leukocyte infiltration into the CNS during acute HIV infection.

Singh VB, Singh MV, Piekna-Przybylska D, Gorantla S, Poluektova LY, Maggirwar SB.

Sci Rep. 2017 Aug 29;7(1):9578. doi: 10.1038/s41598-017-10241-0.

30.

Interface phenomena in magnetron sputtered Cu2O/ZnO heterostructures.

Jensen IJT, Gorantla S, Løvvik OM, Gan J, Nguyen PD, Monakhov E, Svensson BG, Gunnæs AE, Diplas S.

J Phys Condens Matter. 2017 Nov 1;29(43):435002. doi: 10.1088/1361-648X/aa8799.

PMID:
28829336
31.

Electronic properties and morphology of copper oxide/n-type silicon heterostructures.

Lindberg PF, Gorantla SM, Gunnæs AE, Svensson BG, Monakhov EV.

J Phys Condens Matter. 2017 Aug 9;29(31):315701. doi: 10.1088/1361-648X/aa77bc. Epub 2017 Jun 7.

PMID:
28589923
32.

A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy.

Araínga M, Edagwa B, Mosley RL, Poluektova LY, Gorantla S, Gendelman HE.

Retrovirology. 2017 Mar 9;14(1):17. doi: 10.1186/s12977-017-0344-7.

33.

Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs.

Gnanadhas DP, Dash PK, Sillman B, Bade AN, Lin Z, Palandri DL, Gautam N, Alnouti Y, Gelbard HA, McMillan J, Mosley RL, Edagwa B, Gendelman HE, Gorantla S.

J Clin Invest. 2017 Mar 1;127(3):857-873. doi: 10.1172/JCI90025. Epub 2017 Jan 30.

34.

Stranski-Krastanov and Volmer-Weber CVD Growth Regimes To Control the Stacking Order in Bilayer Graphene.

Ta HQ, Perello DJ, Duong DL, Han GH, Gorantla S, Nguyen VL, Bachmatiuk A, Rotkin SV, Lee YH, Rümmeli MH.

Nano Lett. 2016 Oct 12;16(10):6403-6410. doi: 10.1021/acs.nanolett.6b02826. Epub 2016 Oct 3.

PMID:
27683947
35.

Neuropharmacologic Approaches to Restore the Brain's Microenvironment.

Li W, Tong HI, Gorantla S, Poluektova LY, Gendelman HE, Lu Y.

J Neuroimmune Pharmacol. 2016 Sep;11(3):484-94. doi: 10.1007/s11481-016-9686-5. Epub 2016 Jun 28. Review.

36.

Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice.

Singh VB, Singh MV, Gorantla S, Poluektova LY, Maggirwar SB.

Sci Rep. 2016 May 31;6:26876. doi: 10.1038/srep26876.

37.

Metabolic drift in the aging brain.

Ivanisevic J, Stauch KL, Petrascheck M, Benton HP, Epstein AA, Fang M, Gorantla S, Tran M, Hoang L, Kurczy ME, Boska MD, Gendelman HE, Fox HS, Siuzdak G.

Aging (Albany NY). 2016 May;8(5):1000-20. doi: 10.18632/aging.100961.

38.

Novel PKC-ζ to p47 phox interaction is necessary for transformation from blebbishields.

Jinesh GG, Taoka R, Zhang Q, Gorantla S, Kamat AM.

Sci Rep. 2016 Apr 4;6:23965. doi: 10.1038/srep23965.

39.

HIV-1 cellular and tissue replication patterns in infected humanized mice.

Araínga M, Su H, Poluektova LY, Gorantla S, Gendelman HE.

Sci Rep. 2016 Mar 21;6:23513. doi: 10.1038/srep23513.

40.

Low Voltage Transmission Electron Microscopy of Graphene.

Bachmatiuk A, Zhao J, Gorantla SM, Martinez IG, Wiedermann J, Lee C, Eckert J, Rummeli MH.

Small. 2016 Mar 9;12(10):1251. doi: 10.1002/smll.201503609. Epub 2016 Jan 29. No abstract available.

PMID:
26948841
41.

Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV-1 Infection.

Senanayake TH, Gorantla S, Makarov E, Lu Y, Warren G, Vinogradov SV.

Mol Pharm. 2015 Dec 7;12(12):4226-36. doi: 10.1021/acs.molpharmaceut.5b00424. Epub 2015 Nov 13.

42.

Generation and Disease Model Relevance of a Manganese Enhanced Magnetic Resonance Imaging-Based NOD/scid-IL-2Rγc(null) Mouse Brain Atlas.

Sajja BR, Bade AN, Zhou B, Uberti MG, Gorantla S, Gendelman HE, Boska MD, Liu Y.

J Neuroimmune Pharmacol. 2016 Mar;11(1):133-41. doi: 10.1007/s11481-015-9635-8. Epub 2015 Nov 10.

43.

The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy.

Zhang G, Guo D, Dash PK, Araínga M, Wiederin JL, Haverland NA, Knibbe-Hollinger J, Martinez-Skinner A, Ciborowski P, Goodfellow VS, Wysocki TA, Wysocki BJ, Poluektova LY, Liu XM, McMillan JM, Gorantla S, Gelbard HA, Gendelman HE.

Nanomedicine. 2016 Jan;12(1):109-22. doi: 10.1016/j.nano.2015.09.009. Epub 2015 Oct 22.

44.

Influence of age, irradiation and humanization on NSG mouse phenotypes.

Knibbe-Hollinger JS, Fields NR, Chaudoin TR, Epstein AA, Makarov E, Akhter SP, Gorantla S, Bonasera SJ, Gendelman HE, Poluektova LY.

Biol Open. 2015 Sep 9;4(10):1243-52. doi: 10.1242/bio.013201.

45.

Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice.

Bade AN, Gorantla S, Dash PK, Makarov E, Sajja BR, Poluektova LY, Luo J, Gendelman HE, Boska MD, Liu Y.

Mol Neurobiol. 2016 Jul;53(5):3286-3297. doi: 10.1007/s12035-015-9258-3. Epub 2015 Jun 11.

46.

Pharmacodynamics of folic acid receptor targeted antiretroviral nanotherapy in HIV-1-infected humanized mice.

Puligujja P, Araínga M, Dash P, Palandri D, Mosley RL, Gorantla S, Poluektova L, McMillan J, Gendelman HE.

Antiviral Res. 2015 Aug;120:85-8. doi: 10.1016/j.antiviral.2015.05.009. Epub 2015 May 27.

47.

F604S exchange in FIP1L1-PDGFRA enhances FIP1L1-PDGFRA protein stability via SHP-2 and SRC: a novel mode of kinase inhibitor resistance.

Gorantla SP, Zirlik K, Reiter A, Yu C, Illert AL, Von Bubnoff N, Duyster J.

Leukemia. 2015 Aug;29(8):1763-70. doi: 10.1038/leu.2015.70. Epub 2015 Mar 12.

PMID:
25761934
48.

Amphiphilic cationic nanogels as brain-targeted carriers for activated nucleoside reverse transcriptase inhibitors.

Warren G, Makarov E, Lu Y, Senanayake T, Rivera K, Gorantla S, Poluektova LY, Vinogradov SV.

J Neuroimmune Pharmacol. 2015 Mar;10(1):88-101. doi: 10.1007/s11481-014-9576-7. Epub 2015 Jan 6.

49.

Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice.

Boska MD, Dash PK, Knibbe J, Epstein AA, Akhter SP, Fields N, High R, Makarov E, Bonasera S, Gelbard HA, Poluektova LY, Gendelman HE, Gorantla S.

Mol Neurodegener. 2014 Dec 18;9:58. doi: 10.1186/1750-1326-9-58.

50.

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations.

Puligujja P, Balkundi SS, Kendrick LM, Baldridge HM, Hilaire JR, Bade AN, Dash PK, Zhang G, Poluektova LY, Gorantla S, Liu XM, Ying T, Feng Y, Wang Y, Dimitrov DS, McMillan JM, Gendelman HE.

Biomaterials. 2015 Feb;41:141-50. doi: 10.1016/j.biomaterials.2014.11.012. Epub 2014 Dec 9.

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