Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 117

1.

Non-professional phagocytosis: a general feature of normal tissue cells.

Seeberg JC, Loibl M, Moser F, Schwegler M, Büttner-Herold M, Daniel C, Engel FB, Hartmann A, Schlötzer-Schrehardt U, Goppelt-Struebe M, Schellerer V, Naschberger E, Ganzleben I, Heinzerling L, Fietkau R, Distel LV.

Sci Rep. 2019 Aug 15;9(1):11875. doi: 10.1038/s41598-019-48370-3.

2.

Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis.

Schley G, Klanke B, Kalucka J, Schatz V, Daniel C, Mayer M, Goppelt-Struebe M, Herrmann M, Thorsteinsdottir M, Palsson R, Beneke A, Katschinski DM, Burzlaff N, Eckardt KU, Weidemann A, Jantsch J, Willam C.

Kidney Int. 2019 Aug;96(2):378-396. doi: 10.1016/j.kint.2019.02.016. Epub 2019 Mar 5.

PMID:
31146971
3.

Receptor-independent modulation of TGF-β-induced pro-fibrotic pathways by relaxin-2 in human primary tubular epithelial cells.

Grampp S, Goppelt-Struebe M.

Cell Tissue Res. 2018 Dec;374(3):619-627. doi: 10.1007/s00441-018-2904-0. Epub 2018 Aug 4.

PMID:
30078103
4.

HIF stabilization inhibits renal epithelial cell migration and is associated with cytoskeletal alterations.

Müller S, Djudjaj S, Lange J, Iacovescu M, Goppelt-Struebe M, Boor P.

Sci Rep. 2018 Jun 22;8(1):9497. doi: 10.1038/s41598-018-27918-9.

5.

CTGF Is Expressed During Cystic Remodeling in the PKD/Mhm (cy/+) Rat Model for Autosomal-Dominant Polycystic Kidney Disease (ADPKD).

Gauer S, Holzmann Y, Kränzlin B, Hoffmann SC, Gretz N, Hauser IA, Goppelt-Struebe M, Geiger H, Obermüller N.

J Histochem Cytochem. 2017 Dec;65(12):743-755. doi: 10.1369/0022155417735513. Epub 2017 Oct 23.

6.

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway.

Grampp S, Schmid V, Salama R, Lauer V, Kranz F, Platt JL, Smythies J, Choudhry H, Goppelt-Struebe M, Ratcliffe PJ, Mole DR, Schödel J.

PLoS Genet. 2017 Jul 17;13(7):e1006872. doi: 10.1371/journal.pgen.1006872. eCollection 2017 Jul.

7.

The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.

Hermanns C, Hampl V, Holzer K, Aigner A, Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S.

Oncogene. 2017 Jun 15;36(24):3464-3476. doi: 10.1038/onc.2016.496. Epub 2017 Jan 23.

PMID:
28114277
8.

Synergistic induction of CTGF by cytochalasin D and TGFβ-1 in primary human renal epithelial cells: Role of transcriptional regulators MKL1, YAP/TAZ and Smad2/3.

Muehlich S, Rehm M, Ebenau A, Goppelt-Struebe M.

Cell Signal. 2017 Jan;29:31-40. doi: 10.1016/j.cellsig.2016.10.002. Epub 2016 Oct 7.

PMID:
27721022
9.

P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells.

Kraus A, Grampp S, Goppelt-Struebe M, Schreiber R, Kunzelmann K, Peters DJ, Leipziger J, Schley G, Schödel J, Eckardt KU, Buchholz B.

Purinergic Signal. 2016 Dec;12(4):687-695. Epub 2016 Aug 26.

10.

Inhibitors of oxygen sensing prolyl hydroxylases regulate nuclear localization of the transcription factors Smad2 and YAP/TAZ involved in CTGF synthesis.

Preisser F, Giehl K, Rehm M, Goppelt-Struebe M.

Biochim Biophys Acta. 2016 Aug;1863(8):2027-36. doi: 10.1016/j.bbamcr.2016.05.001. Epub 2016 May 5.

11.

Mitoxantrone-loaded superparamagnetic iron oxide nanoparticles as drug carriers for cancer therapy: Uptake and toxicity in primary human tubular epithelial cells.

Cicha I, Scheffler L, Ebenau A, Lyer S, Alexiou C, Goppelt-Struebe M.

Nanotoxicology. 2016;10(5):557-66. doi: 10.3109/17435390.2015.1095364. Epub 2015 Oct 15.

PMID:
26468004
12.

Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation.

Forschbach V, Goppelt-Struebe M, Kunzelmann K, Schreiber R, Piedagnel R, Kraus A, Eckardt KU, Buchholz B.

Cell Death Dis. 2015 Oct 8;6:e1899. doi: 10.1038/cddis.2015.273.

13.

Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells.

Giehl K, Keller C, Muehlich S, Goppelt-Struebe M.

PLoS One. 2015 Mar 27;10(3):e0121589. doi: 10.1371/journal.pone.0121589. eCollection 2015.

14.

Dual inhibition of Src family kinases and Aurora kinases by SU6656 modulates CTGF (connective tissue growth factor) expression in an ERK-dependent manner.

Cicha I, Zitzmann R, Goppelt-Struebe M.

Int J Biochem Cell Biol. 2014 Jan;46:39-48. doi: 10.1016/j.biocel.2013.11.014. Epub 2013 Nov 22.

PMID:
24275091
15.

HIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells.

Weidemann A, Breyer J, Rehm M, Eckardt KU, Daniel C, Cicha I, Giehl K, Goppelt-Struebe M.

Cell Commun Signal. 2013 Oct 21;11:80. doi: 10.1186/1478-811X-11-80.

16.

Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule.

Jobst-Schwan T, Knaup KX, Nielsen R, Hackenbeck T, Buettner-Herold M, Lechler P, Kroening S, Goppelt-Struebe M, Schloetzer-Schrehardt U, Fürnrohr BG, Voll RE, Amann K, Eckardt KU, Christensen EI, Wiesener MS.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F734-44. doi: 10.1152/ajprenal.00546.2012. Epub 2013 Jul 3.

17.

Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells.

Zuehlke J, Ebenau A, Krueger B, Goppelt-Struebe M.

Cell Commun Signal. 2012 Sep 2;10(1):25. doi: 10.1186/1478-811X-10-25.

18.

Distinct mesenchymal alterations in N-cadherin and E-cadherin positive primary renal epithelial cells.

Keller C, Kroening S, Zuehlke J, Kunath F, Krueger B, Goppelt-Struebe M.

PLoS One. 2012;7(8):e43584. doi: 10.1371/journal.pone.0043584. Epub 2012 Aug 17.

19.

A complex microdeletion 17q12 phenotype in a patient with recurrent de novo membranous nephropathy.

Hinkes B, Hilgers KF, Bolz HJ, Goppelt-Struebe M, Amann K, Nagl S, Bergmann C, Rascher W, Eckardt KU, Jacobi J.

BMC Nephrol. 2012 May 14;13:27. doi: 10.1186/1471-2369-13-27.

20.

Inhibition of Rho kinases increases directional motility of microvascular endothelial cells.

Breyer J, Samarin J, Rehm M, Lautscham L, Fabry B, Goppelt-Struebe M.

Biochem Pharmacol. 2012 Mar 1;83(5):616-26. doi: 10.1016/j.bcp.2011.12.012. Epub 2011 Dec 16.

PMID:
22192821
21.

Carotid plaque vulnerability: a positive feedback between hemodynamic and biochemical mechanisms.

Cicha I, Wörner A, Urschel K, Beronov K, Goppelt-Struebe M, Verhoeven E, Daniel WG, Garlichs CD.

Stroke. 2011 Dec;42(12):3502-10. doi: 10.1161/STROKEAHA.111.627265. Epub 2011 Oct 13.

PMID:
21998063
22.

Resveratrol inhibits monocytic cell chemotaxis to MCP-1 and prevents spontaneous endothelial cell migration through Rho kinase-dependent mechanism.

Cicha I, Regler M, Urschel K, Goppelt-Struebe M, Daniel WG, Garlichs CD.

J Atheroscler Thromb. 2011;18(12):1031-42. Epub 2011 Aug 31.

23.

Lack of α8 integrin leads to morphological changes in renal mesangial cells, but not in vascular smooth muscle cells.

Marek I, Volkert G, Jahn A, Fahlbusch F, Zürn C, Ozcan Z, Goppelt-Struebe M, Hilgers KF, Rascher W, Hartner A.

BMC Cell Biol. 2010 Dec 31;11:102. doi: 10.1186/1471-2121-11-102.

24.

Analysis of matrix-dependent cell migration with a barrier migration assay.

Kroening S, Goppelt-Struebe M.

Sci Signal. 2010 Jun 15;3(126):pl1. doi: 10.1126/scisignal.3126pl1.

PMID:
20551431
25.

Linking cell structure to gene regulation: signaling events and expression controls on the model genes PAI-1 and CTGF.

Samarakoon R, Goppelt-Struebe M, Higgins PJ.

Cell Signal. 2010 Oct;22(10):1413-9. doi: 10.1016/j.cellsig.2010.03.020. Epub 2010 Apr 2. Review.

26.

Hic-5 as a regulator of endothelial cell morphology and connective tissue growth factor gene expression.

Komorowsky C, Samarin J, Rehm M, Guidolin D, Goppelt-Struebe M.

J Mol Med (Berl). 2010 Jun;88(6):623-31. doi: 10.1007/s00109-010-0608-3. Epub 2010 Mar 24.

PMID:
20333347
27.

Matrix-independent stimulation of human tubular epithelial cell migration by Rho kinase inhibitors.

Kroening S, Stix J, Keller C, Streiff C, Goppelt-Struebe M.

J Cell Physiol. 2010 Jun;223(3):703-12. doi: 10.1002/jcp.22079.

PMID:
20175114
28.

Differential regulation of connective tissue growth factor in renal cells by histone deacetylase inhibitors.

Komorowsky C, Ocker M, Goppelt-Struebe M.

J Cell Mol Med. 2009 Aug;13(8B):2353-64. doi: 10.1111/j.1582-4934.2009.00674.x.

29.

Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia.

Kroening S, Neubauer E, Wullich B, Aten J, Goppelt-Struebe M.

Am J Physiol Renal Physiol. 2010 Mar;298(3):F796-806. doi: 10.1152/ajprenal.00528.2009. Epub 2009 Dec 23.

30.

The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1.

Schietke R, Warnecke C, Wacker I, Schödel J, Mole DR, Campean V, Amann K, Goppelt-Struebe M, Behrens J, Eckardt KU, Wiesener MS.

J Biol Chem. 2010 Feb 26;285(9):6658-69. doi: 10.1074/jbc.M109.042424. Epub 2009 Dec 21.

31.

FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells.

Samarin J, Wessel J, Cicha I, Kroening S, Warnecke C, Goppelt-Struebe M.

J Biol Chem. 2010 Feb 12;285(7):4328-36. doi: 10.1074/jbc.M109.049650. Epub 2009 Dec 16.

32.

Hypoxia interferes with connective tissue growth factor (CTGF) gene expression in human proximal tubular cell lines.

Kroening S, Neubauer E, Wessel J, Wiesener M, Goppelt-Struebe M.

Nephrol Dial Transplant. 2009 Nov;24(11):3319-25. doi: 10.1093/ndt/gfp305. Epub 2009 Jun 23.

PMID:
19549692
33.

Shear stress preconditioning modulates endothelial susceptibility to circulating TNF-alpha and monocytic cell recruitment in a simplified model of arterial bifurcations.

Cicha I, Beronov K, Ramirez EL, Osterode K, Goppelt-Struebe M, Raaz D, Yilmaz A, Daniel WG, Garlichs CD.

Atherosclerosis. 2009 Nov;207(1):93-102. doi: 10.1016/j.atherosclerosis.2009.04.034. Epub 2009 May 4.

PMID:
19481207
34.

Connective tissue growth factor: context-dependent functions and mechanisms of regulation.

Cicha I, Goppelt-Struebe M.

Biofactors. 2009 Mar-Apr;35(2):200-8. doi: 10.1002/biof.30. Review.

PMID:
19449449
35.

Cell type-specific regulation of CCN2 protein expression by PI3K-AKT-FoxO signaling.

Samarin J, Cicha I, Goppelt-Struebe M.

J Cell Commun Signal. 2009 Mar;3(1):79-84. doi: 10.1007/s12079-009-0055-5. Epub 2009 Apr 24.

36.

Up-regulation of connective tissue growth factor in endothelial cells by the microtubule-destabilizing agent combretastatin A-4.

Samarin J, Rehm M, Krueger B, Waschke J, Goppelt-Struebe M.

Mol Cancer Res. 2009 Feb;7(2):180-8. doi: 10.1158/1541-7786.MCR-08-0292. Epub 2009 Feb 10.

37.

Regulation of connective tissue growth factor (CTGF) by hepatocyte growth factor in human tubular epithelial cells.

Kroening S, Solomovitch S, Sachs M, Wullich B, Goppelt-Struebe M.

Nephrol Dial Transplant. 2009 Mar;24(3):755-62. doi: 10.1093/ndt/gfn530. Epub 2008 Oct 1.

PMID:
18829614
38.

Endothelial dysfunction and monocyte recruitment in cells exposed to non-uniform shear stress.

Cicha I, Goppelt-Struebe M, Yilmaz A, Daniel WG, Garlichs CD.

Clin Hemorheol Microcirc. 2008;39(1-4):113-9.

PMID:
18503117
39.

The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.

Giehl K, Graness A, Goppelt-Struebe M.

Am J Physiol Renal Physiol. 2008 Feb;294(2):F407-13. Epub 2007 Nov 28.

40.

Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor.

Gauer S, Segitz V, Goppelt-Struebe M.

Nephrol Dial Transplant. 2007 Nov;22(11):3154-9. Epub 2007 Jun 30.

PMID:
17602195
41.

Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells.

Gauer S, Hauser IA, Obermüller N, Holzmann Y, Geiger H, Goppelt-Struebe M.

J Cell Biochem. 2008 Feb 1;103(2):615-23.

PMID:
17546625
42.

Pharmacological inhibition of RhoA signaling prevents connective tissue growth factor induction in endothelial cells exposed to non-uniform shear stress.

Cicha I, Goppelt-Struebe M, Muehlich S, Yilmaz A, Raaz D, Daniel WG, Garlichs CD.

Atherosclerosis. 2008 Jan;196(1):136-45. Epub 2007 Apr 23.

PMID:
17452038
43.

Actin-dependent regulation of connective tissue growth factor.

Muehlich S, Cicha I, Garlichs CD, Krueger B, Posern G, Goppelt-Struebe M.

Am J Physiol Cell Physiol. 2007 May;292(5):C1732-8. Epub 2007 Jan 10.

44.

Connective tissue growth factor is released from platelets under high shear stress and is differentially expressed in endothelium along atherosclerotic plaques.

Cicha I, Yilmaz A, Suzuki Y, Maeda N, Daniel WG, Goppelt-Struebe M, Garlichs CD.

Clin Hemorheol Microcirc. 2006;35(1-2):203-6.

PMID:
16899928
45.

Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins.

Chaqour B, Goppelt-Struebe M.

FEBS J. 2006 Aug;273(16):3639-49. Epub 2006 Jul 19. Review.

46.

STAT3-independent inhibition of lysophosphatidic acid-mediated upregulation of connective tissue growth factor (CTGF) by cucurbitacin I.

Graness A, Poli V, Goppelt-Struebe M.

Biochem Pharmacol. 2006 Jun 28;72(1):32-41. Epub 2006 Apr 25.

PMID:
16707113
47.
48.
49.

Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitro.

Cicha I, Yilmaz A, Klein M, Raithel D, Brigstock DR, Daniel WG, Goppelt-Struebe M, Garlichs CD.

Arterioscler Thromb Vasc Biol. 2005 May;25(5):1008-13. Epub 2005 Mar 10.

PMID:
15761189
50.

Monitoring the cellular effects of HMG-CoA reductase inhibitors in vitro and ex vivo.

Cicha I, Schneiderhan-Marra N, Yilmaz A, Garlichs CD, Goppelt-Struebe M.

Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2046-50. Epub 2004 Sep 23.

PMID:
15388523

Supplemental Content

Loading ...
Support Center