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Items: 1 to 50 of 274

1.

Characterization of DNA Double-strand Break Repair Pathways in Diffuse Large B Cell Lymphoma.

Gopalakrishnan V, Dahal S, Radha G, Sharma S, Raghavan SC, Choudhary B.

Mol Carcinog. 2018 Oct 9. doi: 10.1002/mc.22921. [Epub ahead of print]

PMID:
30298948
2.

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.

Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA.

Nat Med. 2018 Oct 8. doi: 10.1038/s41591-018-0197-1. [Epub ahead of print]

PMID:
30297909
3.

Chest Computed Tomography at Radiation Dose of a Posteroanterior and Lateral Chest X-ray Series: a Proof of Principle in Lymphangioleiomyomatosis.

Hu-Wang E, Schuzer JL, Rollison S, Leifer ES, Steveson C, Gopalakrishnan V, Yao J, Machado T, Jones AM, Julien-Williams P, Moss J, Chen MY.

Chest. 2018 Oct 3. pii: S0012-3692(18)32487-5. doi: 10.1016/j.chest.2018.09.007. [Epub ahead of print]

PMID:
30291925
4.

Preclinical Models of Pediatric Brain Tumors-Forging Ahead.

Dobson THW, Gopalakrishnan V.

Bioengineering (Basel). 2018 Oct 2;5(4). pii: E81. doi: 10.3390/bioengineering5040081. Review.

5.

Tunable structure priors for Bayesian rule learning for knowledge integrated biomarker discovery.

Balasubramanian JB, Gopalakrishnan V.

World J Clin Oncol. 2018 Sep 14;9(5):98-109. doi: 10.5306/wjco.v9.i5.98.

6.

Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner.

Vartak SV, Swarup HA, Gopalakrishnan V, Gopinatha VK, Ropars V, Nambiar M, John F, Kothanahally SKS, Kumari R, Kumari N, Ray U, Radha G, Dinesh D, Pandey M, Ananda H, Karki SS, Srivastava M, Charbonnier JB, Choudhary B, Mantelingu K, Raghavan SC.

FEBS J. 2018 Sep 19. doi: 10.1111/febs.14661. [Epub ahead of print]

PMID:
30230716
7.

Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration.

Callegari K, Maegawa S, Bravo-Alegria J, Gopalakrishnan V.

Cell Commun Signal. 2018 Sep 18;16(1):60. doi: 10.1186/s12964-018-0275-5.

8.

The use of intra-articular analgesics to improve outcomes after temporomandibular joint arthrocentesis: a review.

Gopalakrishnan V, Nagori SA, Roy Chowdhury SK, Saxena V.

Oral Maxillofac Surg. 2018 Sep 8. doi: 10.1007/s10006-018-0720-z. [Epub ahead of print] Review.

PMID:
30196484
9.

The efficacy of dextrose prolotherapy over placebo for temporomandibular joint hypermobility: A systematic review and meta-analysis.

Nagori SA, Jose A, Gopalakrishnan V, Roy ID, Chattopadhyay PK, Roychoudhury A.

J Oral Rehabil. 2018 Jul 19. doi: 10.1111/joor.12698. [Epub ahead of print] Review.

PMID:
30024045
10.

"J" waves & Hypothermia".

Panginikkod S, Gupta N, Gopalakrishnan V, Songolo T, Parikh M, Friedman HJ.

QJM. 2018 Jun 23. doi: 10.1093/qjmed/hcy138. [Epub ahead of print] No abstract available.

PMID:
29939369
11.

MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes.

Dhar SS, Zhao D, Lin T, Gu B, Pal K, Wu SJ, Alam H, Lv J, Yun K, Gopalakrishnan V, Flores ER, Northcott PA, Rajaram V, Li W, Shilatifard A, Sillitoe RV, Chen K, Lee MG.

Mol Cell. 2018 Jun 7;70(5):825-841.e6. doi: 10.1016/j.molcel.2018.04.028. Epub 2018 May 31.

PMID:
29861161
12.

A computational framework for the detection of subcortical brain dysmaturation in neonatal MRI using 3D Convolutional Neural Networks.

Ceschin R, Zahner A, Reynolds W, Gaesser J, Zuccoli G, Lo CW, Gopalakrishnan V, Panigrahy A.

Neuroimage. 2018 Sep;178:183-197. doi: 10.1016/j.neuroimage.2018.05.049. Epub 2018 May 21.

PMID:
29793060
13.

Optimization of a secondary VOI protocol for lung imaging in a clinical CT scanner.

Larsen TC, Gopalakrishnan V, Yao J, Nguyen CP, Chen MY, Moss J, Wen H.

J Appl Clin Med Phys. 2018 Jul;19(4):271-280. doi: 10.1002/acm2.12354. Epub 2018 May 21.

14.

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy.

Andrews MC, Reuben A, Gopalakrishnan V, Wargo JA.

Front Immunol. 2018 May 4;9:946. doi: 10.3389/fimmu.2018.00946. eCollection 2018. Review.

15.

The gut microbiota influences anticancer immunosurveillance and general health.

Routy B, Gopalakrishnan V, Daillère R, Zitvogel L, Wargo JA, Kroemer G.

Nat Rev Clin Oncol. 2018 Jun;15(6):382-396. doi: 10.1038/s41571-018-0006-2. Review.

PMID:
29636538
16.

The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy.

Gopalakrishnan V, Helmink BA, Spencer CN, Reuben A, Wargo JA.

Cancer Cell. 2018 Apr 9;33(4):570-580. doi: 10.1016/j.ccell.2018.03.015. Review.

PMID:
29634945
17.

Pseudoneutropenia in lymphangioleiomyomatosis (LAM) patients receiving sirolimus: evaluation in a 100 patient cohort.

Gopalakrishnan V, Jones AM, Julien-Williams P, Machado T, Danner RL, Swigris JJ, Paine R 3rd, Lozier JN, Moss J.

ERJ Open Res. 2018 Mar 20;4(1). pii: 00121-2017. doi: 10.1183/23120541.00121-2017. eCollection 2018 Jan.

18.

Linking Associations of Rare Low-Abundance Species to Their Environments by Association Networks.

Karpinets TV, Gopalakrishnan V, Wargo J, Futreal AP, Schadt CW, Zhang J.

Front Microbiol. 2018 Mar 7;9:297. doi: 10.3389/fmicb.2018.00297. eCollection 2018.

19.

REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.

Shaik S, Kennis B, Maegawa S, Schadler K, Yanwen Y, Callegari K, Lulla RR, Goldman S, Nazarian J, Rajaram V, Fangusaro J, Gopalakrishnan V.

Oncotarget. 2017 Dec 28;9(4):5233-5250. doi: 10.18632/oncotarget.23750. eCollection 2018 Jan 12.

20.

Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial.

Amaria RN, Prieto PA, Tetzlaff MT, Reuben A, Andrews MC, Ross MI, Glitza IC, Cormier J, Hwu WJ, Tawbi HA, Patel SP, Lee JE, Gershenwald JE, Spencer CN, Gopalakrishnan V, Bassett R, Simpson L, Mouton R, Hudgens CW, Zhao L, Zhu H, Cooper ZA, Wani K, Lazar A, Hwu P, Diab A, Wong MK, McQuade JL, Royal R, Lucci A, Burton EM, Reddy S, Sharma P, Allison J, Futreal PA, Woodman SE, Davies MA, Wargo JA.

Lancet Oncol. 2018 Feb;19(2):181-193. doi: 10.1016/S1470-2045(18)30015-9. Epub 2018 Jan 18.

PMID:
29361468
21.

Towards self-learning based hypotheses generation in biomedical text domain.

Gopalakrishnan V, Jha K, Xun G, Ngo HQ, Zhang A.

Bioinformatics. 2018 Jun 15;34(12):2103-2115. doi: 10.1093/bioinformatics/btx837.

PMID:
29293920
22.

Burkholderia Aortic Aneurysm: A Case Report and Review of the Literature.

Panginikkod S, Ramachandran A, Bollimunta P, Habibi R, Kumar Arjal R, Gopalakrishnan V.

Case Rep Infect Dis. 2017;2017:6206395. doi: 10.1155/2017/6206395. Epub 2017 Nov 7.

23.

Targeting P-selectin blocks neuroblastoma growth.

Nolo R, Herbrich S, Rao A, Zweidler-McKay P, Kannan S, Gopalakrishnan V.

Oncotarget. 2017 Sep 28;8(49):86657-86670. doi: 10.18632/oncotarget.21364. eCollection 2017 Oct 17.

24.

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA.

Science. 2018 Jan 5;359(6371):97-103. doi: 10.1126/science.aan4236. Epub 2017 Nov 2.

25.

The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.

Zaky W, Manton C, Miller CP, Khatua S, Gopalakrishnan V, Chandra J.

Cancer Metastasis Rev. 2017 Dec;36(4):617-633. doi: 10.1007/s10555-017-9700-2. Review.

PMID:
29071526
26.

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.

Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, Thaiss CA, Reuben A, Livny J, Avraham R, Frederick DT, Ligorio M, Chatman K, Johnston SE, Mosher CM, Brandis A, Fuks G, Gurbatri C, Gopalakrishnan V, Kim M, Hurd MW, Katz M, Fleming J, Maitra A, Smith DA, Skalak M, Bu J, Michaud M, Trauger SA, Barshack I, Golan T, Sandbank J, Flaherty KT, Mandinova A, Garrett WS, Thayer SP, Ferrone CR, Huttenhower C, Bhatia SN, Gevers D, Wargo JA, Golub TR, Straussman R.

Science. 2017 Sep 15;357(6356):1156-1160. doi: 10.1126/science.aah5043.

27.

BK polyomavirus infection after renal transplantation: Surveillance in a resource-challenged setting.

Bagchi S, Gopalakrishnan V, Srivastava SK, Upadhayay A, Singh G, Bhowmik D, Mahajan S, Dinda A, Agarwal SK.

Transpl Infect Dis. 2017 Dec;19(6). doi: 10.1111/tid.12770. Epub 2017 Oct 25.

PMID:
28834032
28.

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen PL, Beird HC, Garber HR, Roh W, Wani K, Chen E, Haymaker C, Forget MA, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS, Nezi L, Cogdill AP, Bernatchez C, Roszik J, Hwu P, Woodman SE, Chin L, Tawbi H, Davies MA, Gershenwald JE, Amaria RN, Glitza IC, Diab A, Patel SP, Hu J, Lee JE, Grimm EA, Tetzlaff MT, Lazar AJ, Wistuba II, Clise-Dwyer K, Carter BW, Zhang J, Futreal PA, Sharma P, Allison JP, Cooper ZA, Wargo JA.

NPJ Genom Med. 2017;2. pii: 10. doi: 10.1038/s41525-017-0013-8. Epub 2017 Apr 7.

29.

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.

Reuben A, Gittelman R, Gao J, Zhang J, Yusko EC, Wu CJ, Emerson R, Zhang J, Tipton C, Li J, Quek K, Gopalakrishnan V, Chen R, Vence LM, Cascone T, Vignali M, Fujimoto J, Rodriguez-Canales J, Parra ER, Little LD, Gumbs C, Forget MA, Federico L, Haymaker C, Behrens C, Benzeno S, Bernatchez C, Sepesi B, Gibbons DL, Wargo JA, William WN Jr, Swisher S, Heymach JV, Robins H, Lee JJ, Sharma P, Allison JP, Futreal PA, Wistuba II, Zhang J.

Cancer Discov. 2017 Oct;7(10):1088-1097. doi: 10.1158/2159-8290.CD-17-0256. Epub 2017 Jul 21.

30.

Elevated sterol regulatory elementary binding protein 1 and GluA2 levels in the hippocampal nuclear fraction of Genetic Absence Epilepsy Rats from Strasbourg.

Sekar S, Omran E, Gopalakrishnan V, Howland JG, Snutch TP, Taghibiglou C.

Epilepsy Res. 2017 Oct;136:1-4. doi: 10.1016/j.eplepsyres.2017.07.004. Epub 2017 Jul 12.

PMID:
28719803
31.

Vincristine, Ifosfamide, and Doxorubicin for Initial Treatment of Ewing Sarcoma in Adults.

Wagner MJ, Gopalakrishnan V, Ravi V, Livingston JA, Conley AP, Araujo D, Somaiah N, Zarzour MA, Ratan R, Wang WL, Patel SR, Lazar A, Ludwig JA, Benjamin RS.

Oncologist. 2017 Oct;22(10):1271-1277. doi: 10.1634/theoncologist.2016-0464. Epub 2017 Jul 14.

32.

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study.

Qin Y, Petaccia de Macedo M, Reuben A, Forget MA, Haymaker C, Bernatchez C, Spencer CN, Gopalakrishnan V, Reddy S, Cooper ZA, Fulbright OJ, Ramachandran R, Wahl A, Flores E, Thorsen ST, Tavera RJ, Conrad C, Williams MD, Tetzlaff MT, Wang WL, Gombos DS, Esmaeli B, Amaria RN, Hwu P, Wargo JA, Lazar AJ, Patel SP.

Oncoimmunology. 2017 May 8;6(6):e1321187. doi: 10.1080/2162402X.2017.1321187. eCollection 2017.

33.

Synovial Sarcoma of the Head and Neck: A Single Institution Review.

Gopalakrishnan V, Amini B, Wagner MJ, Nowell EN, Lazar AJ, Lin PP, Benjamin RS, Araujo DM.

Sarcoma. 2017;2017:2016752. doi: 10.1155/2017/2016752. Epub 2017 Jun 5.

34.

Sequential phosphorylation of CST subunits by different cyclin-Cdk1 complexes orchestrate telomere replication.

Gopalakrishnan V, Tan CR, Li S.

Cell Cycle. 2017 Jul 3;16(13):1271-1287. doi: 10.1080/15384101.2017.1312235. Epub 2017 Jun 26.

35.

A Benzothiazole Derivative (5g) Induces DNA Damage And Potent G2/M Arrest In Cancer Cells.

Hegde M, Vartak SV, Kavitha CV, Ananda H, Prasanna DS, Gopalakrishnan V, Choudhary B, Rangappa KS, Raghavan SC.

Sci Rep. 2017 May 31;7(1):2533. doi: 10.1038/s41598-017-02489-3.

36.

Interaction of molecular alterations with immune response in melanoma.

Szczepaniak Sloane RA, Gopalakrishnan V, Reddy SM, Zhang X, Reuben A, Wargo JA.

Cancer. 2017 Jun 1;123(S11):2130-2142. doi: 10.1002/cncr.30681. Review.

37.

Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation.

Dobson THW, Hatcher RJ, Swaminathan J, Das CM, Shaik S, Tao RH, Milite C, Castellano S, Taylor PH, Sbardella G, Gopalakrishnan V.

Mol Cancer Res. 2017 Aug;15(8):1073-1084. doi: 10.1158/1541-7786.MCR-16-0424. Epub 2017 May 8.

38.

Sterol regulatory element-binding protein 1 inhibitors decrease pancreatic cancer cell viability and proliferation.

Siqingaowa, Sekar S, Gopalakrishnan V, Taghibiglou C.

Biochem Biophys Res Commun. 2017 Jun 17;488(1):136-140. doi: 10.1016/j.bbrc.2017.05.023. Epub 2017 May 5.

PMID:
28483521
39.

DNA double-strand break repair in Penaeus monodon is predominantly dependent on homologous recombination.

Srivastava S, Dahal S, Naidu SJ, Anand D, Gopalakrishnan V, Kooloth Valappil R, Raghavan SC.

DNA Res. 2017 Apr 1;24(2):117-128. doi: 10.1093/dnares/dsw059.

40.

Learning Parsimonious Classification Rules from Gene Expression Data Using Bayesian Networks with Local Structure.

Lustgarten JL, Balasubramanian JB, Visweswaran S, Gopalakrishnan V.

Data (Basel). 2017 Mar;2(1). pii: 5. doi: 10.3390/data2010005. Epub 2017 Jan 18.

41.

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J, Tetzlaff MT, Davies MA, Gershenwald JE, Tawbi H, Lazar AJ, Hwu P, Hwu WJ, Diab A, Glitza IC, Patel SP, Woodman SE, Amaria RN, Prieto VG, Hu J, Sharma P, Allison JP, Chin L, Zhang J, Wargo JA, Futreal PA.

Sci Transl Med. 2017 Mar 1;9(379). pii: eaah3560. doi: 10.1126/scitranslmed.aah3560. Erratum in: Sci Transl Med. 2017 Apr 12;9(385):.

42.

An Overview and Evaluation of Recent Machine Learning Imputation Methods Using Cardiac Imaging Data.

Liu Y, Gopalakrishnan V.

Data (Basel). 2017 Mar;2(1). pii: 8. doi: 10.3390/data2010008. Epub 2017 Jan 25.

43.

Application of Taxonomic Modeling to Microbiota Data Mining for Detection of Helminth Infection in Global Populations.

Torbati ME, Mitreva M, Gopalakrishnan V.

Data (Basel). 2016 Dec;1(3). pii: 19. doi: 10.3390/data1030019. Epub 2016 Dec 13.

44.

The Case | Labile creatinine levels in a patient with breast cancer.

Kent R, Gopalakrishnan VP, Menon MC, Ross MJ.

Kidney Int. 2017 Mar;91(3):761-762. doi: 10.1016/j.kint.2016.08.004. No abstract available.

PMID:
28202178
45.

Pathogen-mediated manipulation of arthropod microbiota to promote infection.

Abraham NM, Liu L, Jutras BL, Yadav AK, Narasimhan S, Gopalakrishnan V, Ansari JM, Jefferson KK, Cava F, Jacobs-Wagner C, Fikrig E.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E781-E790. doi: 10.1073/pnas.1613422114. Epub 2017 Jan 17.

46.

Ramsay Hunt syndrome.

Gupta NM, Parikh MP, Panginikkod S, Gopalakrishnan V.

QJM. 2016 Oct;109(10):693. Epub 2016 Aug 6. No abstract available.

PMID:
27497069
47.

A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells.

Thomas E, Gopalakrishnan V, Hegde M, Kumar S, Karki SS, Raghavan SC, Choudhary B.

Sci Rep. 2016 Oct 17;6:34653. doi: 10.1038/srep34653.

48.

A novel inhibitor of BCL2, Disarib abrogates tumor growth while sparing platelets, by activating intrinsic pathway of apoptosis.

Vartak SV, Hegde M, Iyer D, Gaikwad S, Gopalakrishnan V, Srivastava M, Karki SS, Choudhary B, Ray P, Santhoshkumar TR, Raghavan SC.

Biochem Pharmacol. 2016 Dec 15;122:10-22. doi: 10.1016/j.bcp.2016.09.028. Epub 2016 Sep 29.

PMID:
27693384
49.

Remineralizing potential of a 60-s in vitro application of Tooth Mousse Plus.

Gopalakrishnan VL, Anthonappa RP, King NM, Itthagarun A.

Int J Paediatr Dent. 2017 Sep;27(5):356-363. doi: 10.1111/ipd.12268. Epub 2016 Sep 23.

PMID:
27659165
50.

Mandibular fracture in a neonate.

Gopalakrishnan V, Sahoo NK, Roy ID.

Int J Oral Maxillofac Surg. 2017 Jan;46(1):59-61. doi: 10.1016/j.ijom.2016.08.009. Epub 2016 Sep 1.

PMID:
27593357

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