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Items: 17


Neoplastic plasma cells generate an inflammatory environment within bone marrow and markedly alter the distribution of T cells between lymphoid compartments.

Goodyear OC, Essex S, Seetharam A, Basu S, Moss P, Pratt G.

Oncotarget. 2017 May 2;8(18):30383-30394. doi: 10.18632/oncotarget.16628.


Tolerability and Clinical Activity of Post-Transplantation Azacitidine in Patients Allografted for Acute Myeloid Leukemia Treated on the RICAZA Trial.

Craddock C, Jilani N, Siddique S, Yap C, Khan J, Nagra S, Ward J, Ferguson P, Hazlewood P, Buka R, Vyas P, Goodyear O, Tholouli E, Crawley C, Russell N, Byrne J, Malladi R, Snowden J, Dennis M.

Biol Blood Marrow Transplant. 2016 Feb;22(2):385-390. doi: 10.1016/j.bbmt.2015.09.004. Epub 2015 Sep 9.


Targeting ß2 adrenergic receptors regulate human T cell function directly and indirectly.

Zalli A, Bosch JA, Goodyear O, Riddell N, McGettrick HM, Moss P, Wallace GR.

Brain Behav Immun. 2015 Mar;45:211-8. doi: 10.1016/j.bbi.2014.12.001. Epub 2014 Dec 16.


MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

Cobbold M, De La Peña H, Norris A, Polefrone JM, Qian J, English AM, Cummings KL, Penny S, Turner JE, Cottine J, Abelin JG, Malaker SA, Zarling AL, Huang HW, Goodyear O, Freeman SD, Shabanowitz J, Pratt G, Craddock C, Williams ME, Hunt DF, Engelhard VH.

Sci Transl Med. 2013 Sep 18;5(203):203ra125. doi: 10.1126/scitranslmed.3006061.


Profile of maternal CD4 T-cell effector function during normal pregnancy and in women with a history of recurrent miscarriage.

Lissauer D, Goodyear O, Khanum R, Moss PA, Kilby MD.

Clin Sci (Lond). 2014 Mar;126(5):347-54. doi: 10.1042/CS20130247.


Fetal-specific CD8+ cytotoxic T cell responses develop during normal human pregnancy and exhibit broad functional capacity.

Lissauer D, Piper K, Goodyear O, Kilby MD, Moss PA.

J Immunol. 2012 Jul 15;189(2):1072-80. doi: 10.4049/jimmunol.1200544. Epub 2012 Jun 8.


Suppression of antigen-specific T cell responses by the Kaposi's sarcoma-associated herpesvirus viral OX2 protein and its cellular orthologue, CD200.

Misstear K, Chanas SA, Rezaee SA, Colman R, Quinn LL, Long HM, Goodyear O, Lord JM, Hislop AD, Blackbourn DJ.

J Virol. 2012 Jun;86(11):6246-57. doi: 10.1128/JVI.07168-11. Epub 2012 Apr 4.


Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML).

Goodyear OC, Dennis M, Jilani NY, Loke J, Siddique S, Ryan G, Nunnick J, Khanum R, Raghavan M, Cook M, Snowden JA, Griffiths M, Russell N, Yin J, Crawley C, Cook G, Vyas P, Moss P, Malladi R, Craddock CF.

Blood. 2012 Apr 5;119(14):3361-9. doi: 10.1182/blood-2011-09-377044. Epub 2012 Jan 10.


Cytomegalovirus sero positivity dramatically alters the maternal CD8+ T cell repertoire and leads to the accumulation of highly differentiated memory cells during human pregnancy.

Lissauer D, Choudhary M, Pachnio A, Goodyear O, Moss PA, Kilby MD.

Hum Reprod. 2011 Dec;26(12):3355-65. doi: 10.1093/humrep/der327. Epub 2011 Oct 5.


Dominant responses with conservation of T-cell receptor usage in the CD8+ T-cell recognition of a cancer testis antigen peptide presented through HLA-Cw7 in patients with multiple myeloma.

Goodyear OC, Pearce H, Pratt G, Moss P.

Cancer Immunol Immunother. 2011 Dec;60(12):1751-61. doi: 10.1007/s00262-011-1070-y. Epub 2011 Jul 23.


Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia.

Goodyear O, Agathanggelou A, Novitzky-Basso I, Siddique S, McSkeane T, Ryan G, Vyas P, Cavenagh J, Stankovic T, Moss P, Craddock C.

Blood. 2010 Sep 16;116(11):1908-18. doi: 10.1182/blood-2009-11-249474. Epub 2010 Jun 8.


CD8(+) T-cell immunity against cancer-testis antigens develops following allogeneic stem cell transplantation and reveals a potential mechanism for the graft-versus-leukemia effect.

McLarnon A, Piper KP, Goodyear OC, Arrazi JM, Mahendra P, Cook M, Clark F, Pratt G, Craddock C, Moss PA.

Haematologica. 2010 Sep;95(9):1572-8. doi: 10.3324/haematol.2009.019539. Epub 2010 May 11.


Differential pattern of CD4+ and CD8+ T-cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma.

Goodyear OC, Pratt G, McLarnon A, Cook M, Piper K, Moss P.

Blood. 2008 Oct 15;112(8):3362-72. doi: 10.1182/blood-2008-04-149393. Epub 2008 Jul 24.


Immunodeficiency and immunotherapy in multiple myeloma.

Pratt G, Goodyear O, Moss P.

Br J Haematol. 2007 Sep;138(5):563-79. Review.


CD8+ T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden.

Goodyear O, Piper K, Khan N, Starczynski J, Mahendra P, Pratt G, Moss P.

Blood. 2005 Dec 15;106(13):4217-24. Epub 2005 Sep 6.


Contract minimum dataset includes confidential data.

Goodyear OM.

BMJ. 1996 Jan 20;312(7024):185. No abstract available.


Integrating a medical database and advisory system.

Goodyear OM, Hobsley M, Jameson DG, Scurr J, Shamsolmaali A.

Med Inform (Lond). 1991 Jul-Sep;16(3):315-21.


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