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Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies.

Mullins SR, Vasilakos JP, Deschler K, Grigsby I, Gillis P, John J, Elder MJ, Swales J, Timosenko E, Cooper Z, Dovedi SJ, Leishman AJ, Luheshi N, Elvecrog J, Tilahun A, Goodwin R, Herbst R, Tomai MA, Wilkinson RW.

J Immunother Cancer. 2019 Sep 11;7(1):244. doi: 10.1186/s40425-019-0724-8.


A phase Ib study of a PI3Kinase inhibitor BKM120 in combination with panitumumab in patients with KRAS wild-type advanced colorectal cancer.

Goodwin R, Jonker D, Chen E, Kennecke H, Cabanero M, Tsao MS, Vickers M, Bohemier C, Lim H, Ritter H, Tu D, Seymour L.

Invest New Drugs. 2019 Sep 10. doi: 10.1007/s10637-019-00814-3. [Epub ahead of print]


Increasing Depression and Substance Use Among Former Smokers in the United States, 2002-2016.

Cheslack-Postava K, Wall MM, Weinberger AH, Goodwin RD.

Am J Prev Med. 2019 Oct;57(4):429-437. doi: 10.1016/j.amepre.2019.05.014. Epub 2019 Aug 20.


A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229).

Chia S, Bedard PL, Hilton J, Amir E, Gelmon K, Goodwin R, Villa D, Cabanero M, Tu D, Tsao M, Seymour L.

Oncologist. 2019 Aug 16. pii: theoncologist.2019-0321. doi: 10.1634/theoncologist.2019-0321. [Epub ahead of print]


Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging.

Hamm GR, Bäckström E, Brülls M, Nilsson A, Strittmatter N, Andrén PE, Grime K, Fridén M, Goodwin RJA.

J Aerosol Med Pulm Drug Deliv. 2019 Jul 31. doi: 10.1089/jamp.2019.1536. [Epub ahead of print]


Smoking relapse risk is increased among individuals in recovery.

Quisenberry AJ, Pittman J, Goodwin RD, Bickel WK, D'Urso G, Sheffer CE.

Drug Alcohol Depend. 2019 Sep 1;202:93-103. doi: 10.1016/j.drugalcdep.2019.07.001. Epub 2019 Jul 8.


An Open and Shut Case: A Lesson in Infective Endocarditis Complications With a Focus on the Mitral-Aortic Intervalvular Fibrosa.

Goodwin EM, Sinner GJ, Goodwin RP, Kotter J.

CASE (Phila). 2019 Mar 28;3(3):115-119. doi: 10.1016/ eCollection 2019 Jun. No abstract available.


Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as predictive and prognostic markers in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiation.

Dudani S, Marginean H, Tang PA, Monzon JG, Raissouni S, Asmis TR, Goodwin RA, Gotfrit J, Cheung WY, Vickers MM.

BMC Cancer. 2019 Jul 5;19(1):664. doi: 10.1186/s12885-019-5892-x.


Untargeted Metabolite Mapping in 3D Cell Culture Models Using High Spectral Resolution FT-ICR Mass Spectrometry Imaging.

Tucker LH, Hamm GR, Sargeant RJE, Goodwin RJA, Mackay CL, Campbell CJ, Clarke DJ.

Anal Chem. 2019 Aug 6;91(15):9522-9529. doi: 10.1021/acs.analchem.9b00661. Epub 2019 Jul 16.


Cannabis use is associated with increased risk of cigarette smoking initiation, persistence, and relapse among adults in the US.

Weinberger AH, Delnevo CD, Wyka K, Gbedemah M, Lee J, Copeland J, Goodwin RD.

Nicotine Tob Res. 2019 May 21. pii: ntz085. doi: 10.1093/ntr/ntz085. [Epub ahead of print]


Correction to: Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging.

Davison AS, Strittmatter N, Sutherland H, Hughes AT, Hughes J, Bou-Gharios G, Milan AM, Goodwin RJA, Ranganath LR, Gallagher JA.

Metabolomics. 2019 May 18;15(5):81. doi: 10.1007/s11306-019-1540-3.


Epidermal growth factor receptor inhibitor-induced hypomagnesemia: a survey of practice patterns among Canadian gastrointestinal medical oncologists.

Thangarasa T, Gotfrit J, Goodwin RA, Tang PA, Clemons M, Imbulgoda A, Vickers MM.

Curr Oncol. 2019 Apr;26(2):e162-e166. doi: 10.3747/co.26.4591. Epub 2019 Apr 1.


Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging.

Davison AS, Strittmatter N, Sutherland H, Hughes AT, Hughes J, Bou-Gharios G, Milan AM, Goodwin RJA, Ranganath LR, Gallagher JA.

Metabolomics. 2019 Apr 29;15(5):68. doi: 10.1007/s11306-019-1531-4. Erratum in: Metabolomics. 2019 May 18;15(5):81.


Trends in Cigar Use in the United States, 2002 to 2016: Diverging Trends by Race/Ethnicity.

Weinberger AH, Delnevo CD, Zhu J, Gbedemah M, Lee J, Cruz LN, Kashan RS, Goodwin RD.

Nicotine Tob Res. 2019 Apr 23. pii: ntz060. doi: 10.1093/ntr/ntz060. [Epub ahead of print]


Racial/ethnic differences in daily, nondaily, and menthol cigarette use and smoking quit ratios in the United States: 2002 to 2016.

Weinberger AH, Giovenco DP, Zhu J, Lee J, Kashan RS, Goodwin RD.

Prev Med. 2019 Aug;125:32-39. doi: 10.1016/j.ypmed.2019.04.009. Epub 2019 Apr 17.


Try to see it my way: exploring the co-design of visual presentations of wellbeing through a workshop process.

Craven MP, Goodwin R, Rawsthorne M, Butler D, Waddingham P, Brown S, Jamieson M.

Perspect Public Health. 2019 May;139(3):153-161. doi: 10.1177/1757913919835231. Epub 2019 Apr 8.


Cigarette smoking quit ratios among adults in the USA with cannabis use and cannabis use disorders, 2002-2016.

Weinberger AH, Pacek LR, Wall MM, Gbedemah M, Lee J, Goodwin RD.

Tob Control. 2019 Apr 5. pii: tobaccocontrol-2018-054590. doi: 10.1136/tobaccocontrol-2018-054590. [Epub ahead of print]


History of Depression and Increased Risk of Sternal Wound Infection After Cardiothoracic Surgery: A Novel and Potentially Modifiable Risk Factor.

Theodore DA, Goodwin RD, Zhang YV, Schneider N, Gordon RJ.

Open Forum Infect Dis. 2019 Feb 15;6(3):ofz083. doi: 10.1093/ofid/ofz083. eCollection 2019 Mar.


Serious psychological distress and daily cannabis use, 2008 to 2016: Potential implications for mental health?

Weinberger AH, Pacek LR, Sheffer CE, Budney AJ, Lee J, Goodwin RD.

Drug Alcohol Depend. 2019 Apr 1;197:134-140. doi: 10.1016/j.drugalcdep.2019.01.010. Epub 2019 Feb 14.


Hypertension as a predictor of advanced colorectal cancer outcome and cetuximab treatment response.

Sud S, O'Callaghan C, Jonker C, Karapetis C, Price T, Tebbutt N, Shapiro J, Van Hazel G, Pavlakis N, Gibbs P, Jeffrey M, Siu L, Gill S, Wong R, Jonker D, Tu D, Goodwin R.

Curr Oncol. 2018 Dec;25(6):e516-e526. doi: 10.3747/co.25.4069. Epub 2018 Dec 1.


Influence of Intraoperative Neuromonitoring on the Outcomes of Surgeries for Pediatric Scoliosis in the United States.

George J, Das S, Egger AC, Chambers RC, Kuivila TE, Goodwin RC.

Spine Deform. 2019 Jan;7(1):27-32. doi: 10.1016/j.jspd.2018.05.013.


HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis.

Dand N, Duckworth M, Baudry D, Russell A, Curtis CJ, Lee SH, Evans I, Mason KJ, Alsharqi A, Becher G, Burden AD, Goodwin RG, McKenna K, Murphy R, Perera GK, Rotarescu R, Wahie S, Wright A, Reynolds NJ, Warren RB, Griffiths CEM, Smith CH, Simpson MA, Barker JN; BADBIR Study Group; BSTOP Study Group; PSORT Consortium.

J Allergy Clin Immunol. 2019 Jun;143(6):2120-2130. doi: 10.1016/j.jaci.2018.11.038. Epub 2018 Dec 20.


A prospective intervention to improve happiness and reduce burnout in oncologists.

Clemons M, Mazzarello S, Pond G, Amir E, Asmis T, Berry S, Brackstone M, Brule S, Goodwin R, Hilton JF, Julião M, Nicholas G, Stewart DJ, Wheatley-Price P, Cholmsky L, Krentel A, Hutton B, Joy AA.

Support Care Cancer. 2019 Apr;27(4):1563-1572. doi: 10.1007/s00520-018-4567-5. Epub 2018 Nov 30.


Cigarette Use Among Individuals with Alcohol Use Disorders in the United States, 2002 to 2016: Trends Overall and by Race/Ethnicity.

Weinberger AH, Pacek LR, Giovenco D, Galea S, Zvolensky MJ, Gbedemah M, Goodwin RD.

Alcohol Clin Exp Res. 2019 Jan;43(1):79-90. doi: 10.1111/acer.13922. Epub 2018 Dec 10.


Predictors of Extended Length of Hospital Stay in Adolescent Idiopathic Scoliosis Patients Undergoing Posterior Segmental Instrumented Fusion: An Analysis of 407 Surgeries Performed at a Large Academic Center.

Sultan AA, Berger RJ, Cantrell WA, Samuel LT, Ramanathan D, Churchill J, Minkara AA, Golubovsky J, Bachour S, Pasadyn S, Karnuta JM, Tamer P, Kuivila TE, Gurd DP, Goodwin RC.

Spine (Phila Pa 1976). 2019 May 15;44(10):715-722. doi: 10.1097/BRS.0000000000002919.


Cigarette smoking among those with mental disorders in the US population: 2012-2013 update.

Smith PH, Chhipa M, Bystrik J, Roy J, Goodwin RD, McKee SA.

Tob Control. 2018 Oct 30. pii: tobaccocontrol-2018-054268. doi: 10.1136/tobaccocontrol-2018-054268. [Epub ahead of print]


Cigarette smoking quit rates among persons with serious psychological distress in the United States from 2008-2016: Are mental health disparities in cigarette use increasing?

Streck JM, Weinberger AH, Pacek LR, Gbedemah M, Goodwin RD.

Nicotine Tob Res. 2018 Oct 23. doi: 10.1093/ntr/nty227. [Epub ahead of print]


LESA MS Imaging of Heat-Preserved and Frozen Tissue: Benefits of Multistep Static FAIMS.

Griffiths RL, Simmonds AL, Swales JG, Goodwin RJA, Cooper HJ.

Anal Chem. 2018 Nov 20;90(22):13306-13314. doi: 10.1021/acs.analchem.8b02739. Epub 2018 Oct 29.


Application of Various Normalization Methods for Microscale Analysis of Tissues Using Direct Analyte Probed Nanoextraction.

de Jesus J, Bunch J, Verbeck G, Webb RP, Costa C, Goodwin RJA, Bailey MJ.

Anal Chem. 2018 Oct 16;90(20):12094-12100. doi: 10.1021/acs.analchem.8b03016. Epub 2018 Sep 27.


Biomechanics of L5/S1 in Long Thoracolumbosacral Constructs: A Cadaveric Study.

Lee BS, Walsh KM, Healy AT, Colbrunn R, Butler RS, Goodwin RC, Steinmetz MP, Mroz TE.

Global Spine J. 2018 Sep;8(6):607-614. doi: 10.1177/2192568218759037. Epub 2018 Mar 20.


Among whom is cigarette smoking declining in the United States? The impact of cannabis use status, 2002-2015.

Pacek LR, Copeland J, Dierker L, Cunningham CO, Martins SS, Goodwin RD.

Drug Alcohol Depend. 2018 Oct 1;191:355-360. doi: 10.1016/j.drugalcdep.2018.01.040. Epub 2018 Apr 11.


Liquid Extraction Surface Analysis (LESA) Electron-Induced Dissociation and Collision-Induced Dissociation Mass Spectrometry of Small Molecule Drug Compounds.

Lopez-Clavijo AF, Griffiths RL, Goodwin RJA, Cooper HJ.

J Am Soc Mass Spectrom. 2018 Nov;29(11):2218-2226. doi: 10.1007/s13361-018-2042-7. Epub 2018 Aug 27.


Trends in cannabis use disorder by cigarette smoking status in the United States, 2002-2016.

Weinberger AH, Pacek LR, Wall MM, Zvolensky MJ, Copeland J, Galea S, Nahvi S, Moeller SJ, Hasin DS, Goodwin RD.

Drug Alcohol Depend. 2018 Oct 1;191:45-51. doi: 10.1016/j.drugalcdep.2018.06.016. Epub 2018 Jul 20.


Cervical sagittal alignment and the impact of posterior spinal instrumented fusion in patients with Lenke type 1 adolescent idiopathic scoliosis.

Berger RJ, Sultan AA, Tanenbaum JE, Cantrell WA, Gurd DP, Kuivila TE, Mroz TE, Steinmetz MP, Goodwin RC.

J Spine Surg. 2018 Jun;4(2):342-348. doi: 10.21037/jss.2018.05.17.


Cost and Affordability of Diets Modelled on Current Eating Patterns and on Dietary Guidelines, for New Zealand Total Population, Māori and Pacific Households.

Mackay S, Buch T, Vandevijvere S, Goodwin R, Korohina E, Funaki-Tahifote M, Lee A, Swinburn B.

Int J Environ Res Public Health. 2018 Jun 13;15(6). pii: E1255. doi: 10.3390/ijerph15061255.


Trends in Illicit Drug Use Among Smokers and Nonsmokers in the United States, 2002-2014.

Moeller SJ, Fink DS, Gbedemah M, Hasin DS, Galea S, Zvolensky MJ, Goodwin RD.

J Clin Psychiatry. 2018 May/Jun;79(3). pii: 17m11718. doi: 10.4088/JCP.17m11718.


Prognostic Value of Anatomical SYNTAX Score and SYNTAX Score II in Veterans With Left Main and/or Three-Vessel Coronary Artery Disease.

Misumida N, Ahmed AE, Barlow M, Goodwin R, Goodwin E, Musa A, Mathbout M, Ogunbayo G, Kim SM, Abdel-Latif A, Ziada KM.

Am J Cardiol. 2018 Jul 15;122(2):213-219. doi: 10.1016/j.amjcard.2018.04.010. Epub 2018 Apr 12.


MALDI Matrix Application Utilizing a Modified 3D Printer for Accessible High Resolution Mass Spectrometry Imaging.

Tucker LH, Conde-González A, Cobice D, Hamm GR, Goodwin RJA, Campbell CJ, Clarke DJ, Mackay CL.

Anal Chem. 2018 Aug 7;90(15):8742-8749. doi: 10.1021/acs.analchem.8b00670. Epub 2018 Jul 27.


Factors associated with post-election psychological distress: The case of the 2016 U.S. presidential election.

Pitcho-Prelorentzos S, Kaniasty K, Hamama-Raz Y, Goodwin R, Ring L, Ben-Ezra M, Mahat-Shamir M.

Psychiatry Res. 2018 Aug;266:1-4. doi: 10.1016/j.psychres.2018.05.008. Epub 2018 May 12.


Trends in Cannabis and Cigarette Use Among Parents With Children at Home: 2002 to 2015.

Goodwin RD, Cheslack-Postava K, Santoscoy S, Bakoyiannis N, Hasin DS, Collins BN, Lepore SJ, Wall MM.

Pediatrics. 2018 Jun;141(6). pii: e20173506. doi: 10.1542/peds.2017-3506. Epub 2018 May 14.


Therapeutic Engineered Hydrogel Coatings Attenuate the Foreign Body Response in Submuscular Implants.

Harmon KA, Lane BA, Boone RE, Afshari A, Berdel HO, Yost MJ, Goodwin RL, Friedman HI, Eberth JF.

Ann Plast Surg. 2018 Jun;80(6S Suppl 6):S410-S417. doi: 10.1097/SAP.0000000000001347.


Frequency of Cannabis Use and Medical Cannabis Use Among Persons Living With HIV in the United States: Findings From a Nationally Representative Sample.

Pacek LR, Towe SL, Hobkirk AL, Nash D, Goodwin RD.

AIDS Educ Prev. 2018 Apr;30(2):169-181. doi: 10.1521/aeap.2018.30.2.169.


Nicotine dependence predicts cannabis use disorder symptoms among adolescents and young adults.

Dierker L, Braymiller J, Rose J, Goodwin R, Selya A.

Drug Alcohol Depend. 2018 Jun 1;187:212-220. doi: 10.1016/j.drugalcdep.2018.02.037. Epub 2018 Apr 16.


Socioeconomic Disparities in Smoking Among U.S. Adults With Depression, 2005-2014.

Weinberger AH, Bandiera FC, Leventhal AM, Dierker LC, Gbedemah M, Tidey JW, Goodwin RD.

Am J Prev Med. 2018 Jun;54(6):765-775. doi: 10.1016/j.amepre.2018.02.008. Epub 2018 Apr 16.


Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging.

Swales JG, Dexter A, Hamm G, Nilsson A, Strittmatter N, Michopoulos F, Hardy C, Morentin-Gutierrez P, Mellor M, Andren PE, Clench MR, Bunch J, Critchlow SE, Goodwin RJA.

Anal Chem. 2018 May 15;90(10):6051-6058. doi: 10.1021/acs.analchem.7b05239. Epub 2018 Apr 26.


Uncovering the regional localization of inhaled salmeterol retention in the lung.

Bäckström E, Hamm G, Nilsson A, Fihn BM, Strittmatter N, Andrén P, Goodwin RJA, Fridén M.

Drug Deliv. 2018 Nov;25(1):838-845. doi: 10.1080/10717544.2018.1455762.


Is Cannabis Use Associated With Increased Risk of Cigarette Smoking Initiation, Persistence, and Relapse? Longitudinal Data From a Representative Sample of US Adults.

Weinberger AH, Platt J, Copeland J, Goodwin RD.

J Clin Psychiatry. 2018 Mar/Apr;79(2). pii: 17m11522. doi: 10.4088/JCP.17m11522.


Evaluation of NeuroPage as a memory aid for people with multiple sclerosis: A randomised controlled trial.

Goodwin RA, Lincoln NB, das Nair R, Bateman A.

Neuropsychol Rehabil. 2018 Mar 20:1-17. doi: 10.1080/09602011.2018.1447973. [Epub ahead of print]


The role of digital communication in patient–clinician communication for NHS providers of specialist clinical services for young people [the Long-term conditions Young people Networked Communication (LYNC) study]: a mixed-methods study.

Griffiths FE, Armoiry X, Atherton H, Bryce C, Buckle A, Cave JAK, Court R, Hamilton K, Dliwayo TR, Dritsaki M, Elder P, Forjaz V, Fraser J, Goodwin R, Huxley C, Ignatowicz A, Karasouli E, Kim SW, Kimani P, Madan JJ, Matharu H, May M, Musumadi L, Paul M, Raut G, Sankaranarayanan S, Slowther AM, Sujan MA, Sutcliffe PA, Svahnstrom I, Taggart F, Uddin A, Verran A, Walker L, Sturt J.

Southampton (UK): NIHR Journals Library; 2018 Feb.

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