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Items: 1 to 50 of 146

1.

A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions.

Cheung R, Insigne KD, Yao D, Burghard CP, Wang J, Hsiao YE, Jones EM, Goodman DB, Xiao X, Kosuri S.

Mol Cell. 2019 Jan 3;73(1):183-194.e8. doi: 10.1016/j.molcel.2018.10.037. Epub 2018 Nov 29.

2.

Enabling multiplexed testing of pooled donor cells through whole-genome sequencing.

Chan Y, Chan YK, Goodman DB, Guo X, Chavez A, Lim ET, Church GM.

Genome Med. 2018 Apr 19;10(1):31. doi: 10.1186/s13073-018-0541-6.

3.

Corrigendum: Engineering and optimising deaminase fusions for genome editing.

Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G.

Nat Commun. 2017 Oct 9;8:16169. doi: 10.1038/ncomms16169.

4.

Millstone: software for multiplex microbial genome analysis and engineering.

Goodman DB, Kuznetsov G, Lajoie MJ, Ahern BW, Napolitano MG, Chen KY, Chen C, Church GM.

Genome Biol. 2017 May 25;18(1):101. doi: 10.1186/s13059-017-1223-1.

5.

Optimizing complex phenotypes through model-guided multiplex genome engineering.

Kuznetsov G, Goodman DB, Filsinger GT, Landon M, Rohland N, Aach J, Lajoie MJ, Church GM.

Genome Biol. 2017 May 25;18(1):100. doi: 10.1186/s13059-017-1217-z.

6.

Engineering and optimising deaminase fusions for genome editing.

Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G.

Nat Commun. 2016 Nov 2;7:13330. doi: 10.1038/ncomms13330. Erratum in: Nat Commun. 2017 Oct 09;8:16169.

7.

DNAplotlib: Programmable Visualization of Genetic Designs and Associated Data.

Der BS, Glassey E, Bartley BA, Enghuus C, Goodman DB, Gordon DB, Voigt CA, Gorochowski TE.

ACS Synth Biol. 2017 Jul 21;6(7):1115-1119. doi: 10.1021/acssynbio.6b00252. Epub 2016 Oct 27.

PMID:
27744689
8.

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli.

Napolitano MG, Landon M, Gregg CJ, Lajoie MJ, Govindarajan L, Mosberg JA, Kuznetsov G, Goodman DB, Vargas-Rodriguez O, Isaacs FJ, Söll D, Church GM.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5588-97. doi: 10.1073/pnas.1605856113. Epub 2016 Sep 6.

9.

Design, synthesis, and testing toward a 57-codon genome.

Ostrov N, Landon M, Guell M, Kuznetsov G, Teramoto J, Cervantes N, Zhou M, Singh K, Napolitano MG, Moosburner M, Shrock E, Pruitt BW, Conway N, Goodman DB, Gardner CL, Tyree G, Gonzales A, Wanner BL, Norville JE, Lajoie MJ, Church GM.

Science. 2016 Aug 19;353(6301):819-22. doi: 10.1126/science.aaf3639.

10.

Rational optimization of tolC as a powerful dual selectable marker for genome engineering.

Gregg CJ, Lajoie MJ, Napolitano MG, Mosberg JA, Goodman DB, Aach J, Isaacs FJ, Church GM.

Nucleic Acids Res. 2014 Apr;42(7):4779-90. doi: 10.1093/nar/gkt1374. Epub 2014 Jan 22.

11.

Genomically recoded organisms expand biological functions.

Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ.

Science. 2013 Oct 18;342(6156):357-60. doi: 10.1126/science.1241459.

12.

Causes and effects of N-terminal codon bias in bacterial genes.

Goodman DB, Church GM, Kosuri S.

Science. 2013 Oct 25;342(6157):475-9. doi: 10.1126/science.1241934. Epub 2013 Sep 26.

13.

Composability of regulatory sequences controlling transcription and translation in Escherichia coli.

Kosuri S, Goodman DB, Cambray G, Mutalik VK, Gao Y, Arkin AP, Endy D, Church GM.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):14024-9. doi: 10.1073/pnas.1301301110. Epub 2013 Aug 7.

14.

A pharmacokinetic, pharmacodynamic, and electrocardiographic study of liposomal mifamurtide (L-MTP-PE) in healthy adult volunteers.

Venkatakrishnan K, Kramer WG, Synold TW, Goodman DB, Sides E 3rd, Oliva C.

Eur J Clin Pharmacol. 2012 Oct;68(10):1347-55. doi: 10.1007/s00228-012-1262-1. Epub 2012 Mar 30.

PMID:
22460239
15.

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.

Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, Church GM.

Science. 2011 Jul 15;333(6040):348-53. doi: 10.1126/science.1205822.

16.

Product length, dye choice, and detection chemistry in the bead-emulsion amplification of millions of single DNA molecules in parallel.

Tiemann-Boege I, Curtis C, Shinde DN, Goodman DB, Tavaré S, Arnheim N.

Anal Chem. 2009 Jul 15;81(14):5770-6. doi: 10.1021/ac900633y.

17.

Electrocardiographic reference ranges derived from 79,743 ambulatory subjects.

Mason JW, Ramseth DJ, Chanter DO, Moon TE, Goodman DB, Mendzelevski B.

J Electrocardiol. 2007 Jul;40(3):228-34. Epub 2007 Feb 5.

PMID:
17276451
18.

Cardiac electrophysiologic monitoring after injection of gadobenate dimeglumine versus placebo in healthy volunteers and patients with cardiovascular disease.

Pirovano G, Goodman DB, Halemane U, Venetianer C, Kirchin MA, Spinazzi A.

Radiology. 2004 Nov;233(2):555-65. Epub 2004 Sep 16.

PMID:
15375224
19.

Measuring the effects of supratherapeutic doses of levofloxacin on healthy volunteers using four methods of QT correction and periodic and continuous ECG recordings.

Noel GJ, Goodman DB, Chien S, Solanki B, Padmanabhan M, Natarajan J.

J Clin Pharmacol. 2004 May;44(5):464-73.

PMID:
15102866
20.

Pindolol does not augment cortisol and prolactin responses to paroxetine in healthy subjects.

Brunswick DJ, Goodman DB, O'Reardon JP, Chopra M, Amsterdam JD.

Prog Neuropsychopharmacol Biol Psychiatry. 2004 May;28(3):477-80.

PMID:
15093954
21.

Effects of three fluoroquinolones on QT interval in healthy adults after single doses.

Noel GJ, Natarajan J, Chien S, Hunt TL, Goodman DB, Abels R.

Clin Pharmacol Ther. 2003 Apr;73(4):292-303.

PMID:
12709719
22.

Murine macrophages stimulated with central and peripheral nervous system myelin or purified myelin proteins release inflammatory products.

Constantinescu CS, Goodman DB, Hilliard B, Wysocka M, Cohen JA.

Neurosci Lett. 2000 Jun 30;287(3):171-4.

PMID:
10863022
23.

Autoantibody disturbances in affective disorders: a function of age and gender?

Hornig M, Amsterdam JD, Kamoun M, Goodman DB.

J Affect Disord. 1999 Sep;55(1):29-37.

PMID:
10512603
24.

Captopril and lisinopril suppress production of interleukin-12 by human peripheral blood mononuclear cells.

Constantinescu CS, Goodman DB, Ventura ES.

Immunol Lett. 1998 May;62(1):25-31.

PMID:
9672144
25.

Positive and negative acute phase proteins in affective subtypes.

Hornig M, Goodman DB, Kamoun M, Amsterdam JD.

J Affect Disord. 1998 Apr;49(1):9-18.

PMID:
9574855
26.

The seroprevalence of the rubeola antibody in a prenatal screening program.

Neubert AG, Samuels P, Goodman DB, Rose NC.

Obstet Gynecol. 1997 Oct;90(4 Pt 1):507-10.

PMID:
9380305
27.

Serum angiotensin-converting enzyme in multiple sclerosis.

Constantinescu CS, Goodman DB, Grossman RI, Mannon LJ, Cohen JA.

Arch Neurol. 1997 Aug;54(8):1012-5.

PMID:
9267976
28.

Transmission of hepatitis viruses by surgeons.

Goodman DB.

N Engl J Med. 1996 Jul 25;335(4):284; author reply 285-7. No abstract available.

PMID:
8657249
29.

The effect of renal function on serum levels of CA 125.

Menzin AW, Kobrin S, Pollak E, Goodman DB, Rubin SC.

Gynecol Oncol. 1995 Sep;58(3):375-7.

PMID:
7672704
30.

Immunolocalization of ubiquitin in degenerating insect flight muscle.

Davis WL, Jacoby BH, Goodman DB.

Histochem J. 1994 Apr;26(4):298-305.

PMID:
8040003
31.

Maternal serum alpha-fetoprotein screening for chromosomal abnormalities: a prospective study in women aged 35 and older.

Rose NC, Palomaki GE, Haddow JE, Goodman DB, Mennuti MT.

Am J Obstet Gynecol. 1994 Apr;170(4):1073-8; discussion 1078-80.

PMID:
7513121
32.

Tumor necrosis factor and coxsackie B4 rhabdomyolysis.

Konrad RJ, Goodman DB, Davis WL.

Ann Intern Med. 1993 Oct 15;119(8):861. No abstract available.

PMID:
8397486
33.

Fundamental principles involved in developing a new saliva-based diagnostic test.

Goodman DB.

Ann N Y Acad Sci. 1993 Sep 20;694:78-85. Review. No abstract available.

PMID:
8215088
34.

Superoxide formation preceding flight muscle histolysis in Solenopsis: fine structural cytochemistry and biochemistry.

Davis WL, Jacoby BH, Jones RG, Goodman DB.

Histochem J. 1993 Jul;25(7):478-90.

PMID:
8407359
35.
36.

Brief report: myeloma-associated paraprotein directed against the HIV-1 p24 antigen in an HIV-1-seropositive patient.

Konrad RJ, Kricka LJ, Goodman DB, Goldman J, Silberstein LE.

N Engl J Med. 1993 Jun 24;328(25):1817-9. No abstract available.

37.

Insulin accelerates the post germinative development of several fat-storing seeds.

Goodman DB, Davis WL.

Biochem Biophys Res Commun. 1993 Jan 29;190(2):440-6.

PMID:
8427587
38.

Simple qualitative immunoassay of human anti-mouse antibodies evaluated.

Kricka LJ, Nozaki O, Goodman DB, Ji X.

Clin Chem. 1992 Dec;38(12):2558-60. No abstract available.

PMID:
1458602
39.

Evidence for the glyoxylate cycle in human liver.

Davis WL, Goodman DB.

Anat Rec. 1992 Dec;234(4):461-8.

PMID:
1456449
40.

The utility of the TDx test in the assessment of fetal lung maturity.

Steinfeld JD, Samuels P, Bulley MA, Cohen AW, Goodman DB, Senior MB.

Obstet Gynecol. 1992 Mar;79(3):460-4.

PMID:
1738531
41.

Human immunodeficiency virus infection in cases presenting to the Philadelphia Medical Examiner's Office.

Resnick D, Hellman F, Mirchandani H, Goodman DB.

Am J Forensic Med Pathol. 1991 Sep;12(3):200-3.

PMID:
1750389
42.

Cryofixation, ultracryomicrotomy, and X-ray microanalysis of enterocytes from chick duodenum: vitamin-D-induced formation of an apical tubulovesicular system.

Davis WL, Hagler HK, Jones RG, Farmer GR, Cooper OJ, Martin JH, Bridges GE, Goodman DB.

Anat Rec. 1991 Feb;229(2):227-39.

PMID:
2012310
43.

Markedly increased concentrations of ferritin in an AIDS patient with disseminated histoplasmosis.

Remaley AT, Goodman DB.

Clin Chem. 1990 Nov;36(11):1992-3. No abstract available.

44.

Identification of glyoxylate cycle enzymes in chick liver--the effect of vitamin D3: cytochemistry and biochemistry.

Davis WL, Jones RG, Farmer GR, Dickerson T, Cortinas E, Cooper OJ, Crawford L, Goodman DB.

Anat Rec. 1990 Jul;227(3):271-84.

PMID:
2164796
45.

Immunolocalization of secretory protein-I or chromogranin A in amphibian urinary bladder granular cell granules.

Davis WL, Schmid KO, Huettner JW, Farmer GR, Jacoby BH, Goodman DB.

Cell Biol Int Rep. 1990 Jul;14(7):601-12.

PMID:
2118425
46.

Interference by human anti-mouse antibody in two-site immunoassays.

Kricka LJ, Schmerfeld-Pruss D, Senior M, Goodman DB, Kaladas P.

Clin Chem. 1990 Jun;36(6):892-4.

47.

Hibernation activates glyoxylate cycle and gluconeogenesis in black bear brown adipose tissue.

Davis WL, Goodman DB, Crawford LA, Cooper OJ, Matthews JL.

Biochim Biophys Acta. 1990 Mar 9;1051(3):276-8.

PMID:
2310778
48.

Discordant hCG measurements in a patient with a carcinoma.

Remaley AT, Bulley M, Senior MB, Goodman DB.

Clin Chem. 1989 Jun;35(6):1259-60. No abstract available.

49.

The immunohistochemical localization of superoxide dismutase activity in the avian epithelial growth plate.

Davis WL, Kipnis M, Shibata K, Farmer GR, Cortinas E, Matthews JL, Goodman DB.

Histochem J. 1989 Apr;21(4):210-5.

PMID:
2777635
50.

Glyoxylate cycle in the epiphyseal growth plate: isocitrate lyase and malate synthase identified in mammalian cartilage.

Davis WL, Jones RG, Farmer GR, Matthews JL, Goodman DB.

Anat Rec. 1989 Apr;223(4):357-62.

PMID:
2712349

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