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Alternative splicing is required for stage differentiation in malaria parasites.

Yeoh LM, Goodman CD, Mollard V, McHugh E, Lee VV, Sturm A, Cozijnsen A, McFadden GI, Ralph SA.

Genome Biol. 2019 Aug 1;20(1):151. doi: 10.1186/s13059-019-1756-6.


Anti-plasmodial Effects of Zanthoxylum zanthoxyloides.

Goodman CD, Hoang AT, Diallo D, Malterud KE, McFadden GI, Wangensteen H.

Planta Med. 2019 Sep;85(13):1073-1079. doi: 10.1055/a-0973-0067. Epub 2019 Jul 31.


Bed Nets, Insecticides, and Antimalarials: Where to Next?

Buchanan HD, McFadden GI, Goodman CD.

Trends Parasitol. 2019 Sep;35(9):668-670. doi: 10.1016/ Epub 2019 Jul 11.


Stereotactic Ablative Radiation Therapy Versus Surgery in Early Lung Cancer: A Meta-analysis of Propensity Score Studies.

Chen H, Laba JM, Boldt RG, Goodman CD, Palma DA, Senan S, Louie AV.

Int J Radiat Oncol Biol Phys. 2018 May 1;101(1):186-194. doi: 10.1016/j.ijrobp.2018.01.064. Epub 2018 Feb 3.


Host biotin is required for liver stage development in malaria parasites.

Dellibovi-Ragheb TA, Jhun H, Goodman CD, Walters MS, Ragheb DRT, Matthews KA, Rajaram K, Mishra S, McFadden GI, Sinnis P, Prigge ST.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2604-E2613. doi: 10.1073/pnas.1800717115. Epub 2018 Feb 26.


Validation of Putative Apicoplast-Targeting Drugs Using a Chemical Supplementation Assay in Cultured Human Malaria Parasites.

Uddin T, McFadden GI, Goodman CD.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01161-17. doi: 10.1128/AAC.01161-17. Print 2018 Jan.


Comparative transcriptomics of female and male gametocytes in Plasmodium berghei and the evolution of sex in alveolates.

Yeoh LM, Goodman CD, Mollard V, McFadden GI, Ralph SA.

BMC Genomics. 2017 Sep 18;18(1):734. doi: 10.1186/s12864-017-4100-0.


A genetic screen in rodent malaria parasites identifies five new apicoplast putative membrane transporters, one of which is essential in human malaria parasites.

Sayers CP, Mollard V, Buchanan HD, McFadden GI, Goodman CD.

Cell Microbiol. 2018 Jan;20(1). doi: 10.1111/cmi.12789. Epub 2017 Nov 9.


Erratum to: Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite.

Goodman CD, Austarheim I, Mollard V, Mikolo B, Malterud KE, McFadden GI, Wangensteen H.

Malar J. 2016 Nov 17;15(1):560. No abstract available.


Targeting Protein Translation in Organelles of the Apicomplexa.

Goodman CD, Pasaje CFA, Kennedy K, McFadden GI, Ralph SA.

Trends Parasitol. 2016 Dec;32(12):953-965. doi: 10.1016/ Epub 2016 Oct 25. Review.


Is the Mitochondrion a Good Malaria Drug Target?

Goodman CD, Buchanan HD, McFadden GI.

Trends Parasitol. 2017 Mar;33(3):185-193. doi: 10.1016/ Epub 2016 Oct 24. Review.


Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite.

Goodman CD, Austarheim I, Mollard V, Mikolo B, Malterud KE, McFadden GI, Wangensteen H.

Malar J. 2016 Sep 20;15:481. doi: 10.1186/s12936-016-1533-x. Erratum in: Malar J. 2016 Nov 17;15(1):560.


Targeting of a Transporter to the Outer Apicoplast Membrane in the Human Malaria Parasite Plasmodium falciparum.

Lim L, Sayers CP, Goodman CD, McFadden GI.

PLoS One. 2016 Jul 21;11(7):e0159603. doi: 10.1371/journal.pone.0159603. eCollection 2016. Erratum in: PLoS One. 2016;11(8):e0161420.


Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast.

Shears MJ, MacRae JI, Mollard V, Goodman CD, Sturm A, Orchard LM, Llinás M, McConville MJ, Botté CY, McFadden GI.

Cell Microbiol. 2017 Jan;19(1). doi: 10.1111/cmi.12633. Epub 2016 Aug 1.


Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes.

Goodman CD, Siregar JE, Mollard V, Vega-Rodríguez J, Syafruddin D, Matsuoka H, Matsuzaki M, Toyama T, Sturm A, Cozijnsen A, Jacobs-Lorena M, Kita K, Marzuki S, McFadden GI.

Science. 2016 Apr 15;352(6283):349-53. doi: 10.1126/science.aad9279.


Evaluation of Health Economics in Radiation Oncology: A Systematic Review.

Nguyen TK, Goodman CD, Boldt RG, Warner A, Palma DA, Rodrigues GB, Lock MI, Mishra MV, Zaric GS, Louie AV.

Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1006-14. doi: 10.1016/j.ijrobp.2015.12.359. Epub 2015 Dec 24. Review.


The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice.

Kalanon M, Bargieri D, Sturm A, Matthews K, Ghosh S, Goodman CD, Thiberge S, Mollard V, McFadden GI, Ménard R, de Koning-Ward TF.

Cell Microbiol. 2016 Mar;18(3):399-412. doi: 10.1111/cmi.12520. Epub 2015 Oct 14.


Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.

Wilson DW, Goodman CD, Sleebs BE, Weiss GE, de Jong NW, Angrisano F, Langer C, Baum J, Crabb BS, Gilson PR, McFadden GI, Beeson JG.

BMC Biol. 2015 Jul 18;13:52. doi: 10.1186/s12915-015-0162-0.


A serine-arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii.

Yeoh LM, Goodman CD, Hall NE, van Dooren GG, McFadden GI, Ralph SA.

Nucleic Acids Res. 2015 May 19;43(9):4661-75. doi: 10.1093/nar/gkv311. Epub 2015 Apr 13.


Mitochondrial ATP synthase is dispensable in blood-stage Plasmodium berghei rodent malaria but essential in the mosquito phase.

Sturm A, Mollard V, Cozijnsen A, Goodman CD, McFadden GI.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10216-23. doi: 10.1073/pnas.1423959112. Epub 2015 Mar 23.


Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites.

Smith CM, Jerkovic A, Puy H, Winship I, Deybach JC, Gouya L, van Dooren G, Goodman CD, Sturm A, Manceau H, McFadden GI, David P, Mercereau-Puijalon O, Burgio G, McMorran BJ, Foote SJ.

Blood. 2015 Jan 15;125(3):534-41. doi: 10.1182/blood-2014-04-567149. Epub 2014 Nov 20.


Synthesis and antimalarial activity of prodigiosenes.

Marchal E, Smithen DA, Uddin MI, Robertson AW, Jakeman DL, Mollard V, Goodman CD, MacDougall KS, McFarland SA, McFadden GI, Thompson A.

Org Biomol Chem. 2014 Jun 28;12(24):4132-42. doi: 10.1039/c3ob42548g.


Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.

Trenholme K, Marek L, Duffy S, Pradel G, Fisher G, Hansen FK, Skinner-Adams TS, Butterworth A, Ngwa CJ, Moecking J, Goodman CD, McFadden GI, Sumanadasa SD, Fairlie DP, Avery VM, Kurz T, Andrews KT.

Antimicrob Agents Chemother. 2014 Jul;58(7):3666-78. doi: 10.1128/AAC.02721-13. Epub 2014 Apr 14.


Apicoplast acetyl Co-A carboxylase of the human malaria parasite is not targeted by cyclohexanedione herbicides.

Goodman CD, Mollard V, Louie T, Holloway GA, Watson KG, McFadden GI.

Int J Parasitol. 2014 Apr;44(5):285-9. doi: 10.1016/j.ijpara.2014.01.007. Epub 2014 Feb 25.


The Plasmodium translocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth.

Matthews K, Kalanon M, Chisholm SA, Sturm A, Goodman CD, Dixon MW, Sanders PR, Nebl T, Fraser F, Haase S, McFadden GI, Gilson PR, Crabb BS, de Koning-Ward TF.

Mol Microbiol. 2013 Sep;89(6):1167-86. doi: 10.1111/mmi.12334. Epub 2013 Aug 15.


Defining the timing of action of antimalarial drugs against Plasmodium falciparum.

Wilson DW, Langer C, Goodman CD, McFadden GI, Beeson JG.

Antimicrob Agents Chemother. 2013 Mar;57(3):1455-67. doi: 10.1128/AAC.01881-12. Epub 2013 Jan 14.


Targeting apicoplasts in malaria parasites.

Goodman CD, McFadden GI.

Expert Opin Ther Targets. 2013 Feb;17(2):167-77. doi: 10.1517/14728222.2013.739158. Epub 2012 Dec 11. Review.


Chemobiosynthesis of new antimalarial macrolides.

Goodman CD, Useglio M, Peirú S, Labadie GR, McFadden GI, Rodríguez E, Gramajo H.

Antimicrob Agents Chemother. 2013 Feb;57(2):907-13. doi: 10.1128/AAC.01825-12. Epub 2012 Dec 3.


Low prevalence of Pneumocystis pneumonia (PCP) but high prevalence of pneumocystis dihydropteroate synthase (dhps) gene mutations in HIV-infected persons in Uganda.

Taylor SM, Meshnick SR, Worodria W, Andama A, Cattamanchi A, Davis JL, Yoo SD, Byanyima P, Kaswabuli S, Goodman CD, Huang L; International HIV-associated Opportunistic Pneumonias Study.

PLoS One. 2012;7(11):e49991. doi: 10.1371/journal.pone.0049991. Epub 2012 Nov 16.


Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.

Sumanadasa SD, Goodman CD, Lucke AJ, Skinner-Adams T, Sahama I, Haque A, Do TA, McFadden GI, Fairlie DP, Andrews KT.

Antimicrob Agents Chemother. 2012 Jul;56(7):3849-56. doi: 10.1128/AAC.00030-12. Epub 2012 Apr 16.


Dual targeting of aminoacyl-tRNA synthetases to the apicoplast and cytosol in Plasmodium falciparum.

Jackson KE, Pham JS, Kwek M, De Silva NS, Allen SM, Goodman CD, McFadden GI, Ribas de Pouplana L, Ralph SA.

Int J Parasitol. 2012 Feb;42(2):177-86. doi: 10.1016/j.ijpara.2011.11.008. Epub 2011 Dec 24.


Low prevalence of Pneumocystis jirovecii lung colonization in Ugandan HIV-infected patients hospitalized with non-Pneumocystis pneumonia.

Taylor SM, Meshnick SR, Worodria W, Andama A, Davis JL, Cattamanchi A, den Boon S, Yoo SD, Goodman CD, Huang L; International HIV-associated Opportunistic Pneumonias (IHOP) Study.

Diagn Microbiol Infect Dis. 2012 Feb;72(2):139-43. doi: 10.1016/j.diagmicrobio.2011.10.009. Epub 2011 Dec 5.


The evolution of virulence in non-o157 shiga toxin-producing Escherichia coli.

Coombes BK, Gilmour MW, Goodman CD.

Front Microbiol. 2011 Apr 25;2:90. doi: 10.3389/fmicb.2011.00090. eCollection 2011.


Characterization of two malaria parasite organelle translation elongation factor G proteins: the likely targets of the anti-malarial fusidic acid.

Johnson RA, McFadden GI, Goodman CD.

PLoS One. 2011;6(6):e20633. doi: 10.1371/journal.pone.0020633. Epub 2011 Jun 10.


Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.

Nair SC, Brooks CF, Goodman CD, Sturm A, McFadden GI, Sundriyal S, Anglin JL, Song Y, Moreno SN, Striepen B.

J Exp Med. 2011 Jul 4;208(7):1547-59. doi: 10.1084/jem.20110039. Epub 2011 Jun 20. Erratum in: J Exp Med. 2012 May 7;209(5):1051. Strurm, Angelika [corrected to Sturm, Angelika].


Ciliate pellicular proteome identifies novel protein families with characteristic repeat motifs that are common to alveolates.

Gould SB, Kraft LG, van Dooren GG, Goodman CD, Ford KL, Cassin AM, Bacic A, McFadden GI, Waller RF.

Mol Biol Evol. 2011 Mar;28(3):1319-31. doi: 10.1093/molbev/msq321. Epub 2010 Dec 2.


The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.

El Bakkouri M, Pow A, Mulichak A, Cheung KL, Artz JD, Amani M, Fell S, de Koning-Ward TF, Goodman CD, McFadden GI, Ortega J, Hui R, Houry WA.

J Mol Biol. 2010 Dec 3;404(3):456-77. doi: 10.1016/j.jmb.2010.09.051. Epub 2010 Sep 29.


Dimeric cyclohexane-1,3-dione oximes inhibit wheat acetyl-CoA carboxylase and show anti-malarial activity.

Louie T, Goodman CD, Holloway GA, McFadden GI, Mollard V, Watson KG.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4611-3. doi: 10.1016/j.bmcl.2010.06.007. Epub 2010 Jun 8.


Apicoplast and mitochondrion in gametocytogenesis of Plasmodium falciparum.

Okamoto N, Spurck TP, Goodman CD, McFadden GI.

Eukaryot Cell. 2009 Jan;8(1):128-32. doi: 10.1128/EC.00267-08. Epub 2008 Nov 7.


A miRNA signature of prion induced neurodegeneration.

Saba R, Goodman CD, Huzarewich RL, Robertson C, Booth SA.

PLoS One. 2008;3(11):e3652. doi: 10.1371/journal.pone.0003652. Epub 2008 Nov 6.


Gamete fusion: key protein identified.

Goodman CD, McFadden GI.

Curr Biol. 2008 Jul 8;18(13):R571-3. doi: 10.1016/j.cub.2008.05.007.


Fatty acid synthesis in protozoan parasites: unusual pathways and novel drug targets.

Goodman CD, McFadden GI.

Curr Pharm Des. 2008;14(9):901-16. Review.


The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

Goodman CD, Su V, McFadden GI.

Mol Biochem Parasitol. 2007 Apr;152(2):181-91. Epub 2007 Jan 9.


Fatty acid biosynthesis as a drug target in apicomplexan parasites.

Goodman CD, McFadden GI.

Curr Drug Targets. 2007 Jan;8(1):15-30. Review.


A multidrug resistance-associated protein involved in anthocyanin transport in Zea mays.

Goodman CD, Casati P, Walbot V.

Plant Cell. 2004 Jul;16(7):1812-26. Epub 2004 Jun 18.


Measurement of gamow-teller strength for 176Yb --> 176Lu and the efficiency of a solar neutrino detector

Bhattacharya M, Goodman CD, Raghavan RS, Palarczyk M, Garcia A, Rapaport J, van Heerden IJ, Zupranski P.

Phys Rev Lett. 2000 Nov 20;85(21):4446-9.


Gamow-teller strengths of the inverse beta transition 176Yb-->176Lu for spectroscopy of proton-proton and other sub-MeV solar neutrinos

Fujiwara M, Akimune H, van Den Berg AM, Cribier M, Daito I I, Ejiri H, Fujimura H, Fujita Y, Goodman CD, Hara K, Harakeh MN, Ihara F, Ishikawa T, Janecke J, Kawabata T, Raghavan RS, Schwarz K, Tanaka M, Yamanaka T, Yosoi M, Zegers RG.

Phys Rev Lett. 2000 Nov 20;85(21):4442-5.


AN9, a petunia glutathione S-transferase required for anthocyanin sequestration, is a flavonoid-binding protein.

Mueller LA, Goodman CD, Silady RA, Walbot V.

Plant Physiol. 2000 Aug;123(4):1561-70.

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