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Items: 1 to 50 of 243

1.

Multi-Omics Strategies Uncover Host-Pathogen Interactions.

Khan MM, Ernst O, Manes NP, Oyler BL, Fraser IDC, Goodlett DR, Nita-Lazar A.

ACS Infect Dis. 2019 Apr 12;5(4):493-505. doi: 10.1021/acsinfecdis.9b00080. Epub 2019 Mar 25.

PMID:
30857388
2.

Temporal proteomic profiling reveals changes that support Burkholderia biofilms.

Khan MM, Chattagul S, Tran BQ, Freiberg JA, Nita-Lazar A, Shirtliff ME, Sermswan RW, Ernst RK, Goodlett DR.

Pathog Dis. 2019 Mar 1;77(2). pii: ftz005. doi: 10.1093/femspd/ftz005.

PMID:
30759239
3.

The effect of embryonic origin on the osteoinductive potential of bone allografts.

Homayounfar N, Khan MM, Ji Y, Khoury ZH, Oates TW, Goodlett DR, Chellaiah M, Masri R.

J Prosthet Dent. 2019 Apr;121(4):651-658. doi: 10.1016/j.prosdent.2018.09.003. Epub 2018 Dec 28.

PMID:
30598313
4.

Rapid Microbial Identification and Antibiotic Resistance Detection by Mass Spectrometric Analysis of Membrane Lipids.

Liang T, Leung LM, Opene B, Fondrie WE, Lee YI, Chandler CE, Yoon SH, Doi Y, Ernst RK, Goodlett DR.

Anal Chem. 2019 Jan 15;91(2):1286-1294. doi: 10.1021/acs.analchem.8b02611. Epub 2019 Jan 4.

PMID:
30571097
5.

A Prospective Study of Acinetobacter baumannii Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids.

Leung LM, McElheny CL, Gardner FM, Chandler CE, Bowler SL, Mettus RT, Spychala CN, Fowler EL, Opene BNA, Myers RA, Goodlett DR, Doi Y, Ernst RK.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e01100-18. doi: 10.1128/JCM.01100-18. Print 2019 Mar.

PMID:
30567747
6.

Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids.

Fondrie WE, Liang T, Oyler BL, Leung LM, Ernst RK, Strickland DK, Goodlett DR.

Sci Rep. 2018 Oct 26;8(1):15857. doi: 10.1038/s41598-018-33681-8.

7.

Rapid Food Product Analysis by Surface Acoustic Wave Nebulization Coupled Mass Spectrometry.

Schneider T, Oyler BL, Yoon SH, Liang T, Yen GS, Kilgour DPA, Nilsson E, Goodlett DR.

Food Anal Methods. 2018 Sep;11(9):2447-2454. doi: 10.1007/s12161-018-1232-z. Epub 2018 Mar 21.

PMID:
30271524
8.

Mass Spectrometry-based Structural Analysis and Systems Immunoproteomics Strategies for Deciphering the Host Response to Endotoxin.

Khan MM, Ernst O, Sun J, Fraser IDC, Ernst RK, Goodlett DR, Nita-Lazar A.

J Mol Biol. 2018 Aug 17;430(17):2641-2660. doi: 10.1016/j.jmb.2018.06.032. Epub 2018 Jun 24. Review.

PMID:
29949751
9.

Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis.

Bhosale SD, Moulder R, Venäläinen MS, Koskinen JS, Pitkänen N, Juonala MT, Kähönen MAP, Lehtimäki TJ, Viikari JSA, Elo LL, Goodlett DR, Lahesmaa R, Raitakari OT.

Sci Rep. 2018 Jun 15;8(1):9209. doi: 10.1038/s41598-018-27265-9.

10.

Dataset describing the development, optimization and application of SRM/MRM based targeted proteomics strategy for quantification of potential biomarkers of EGFR TKI sensitivity.

Awasthi S, Maity T, Oyler BL, Zhang X, Goodlett DR, Guha U.

Data Brief. 2018 May 2;19:424-436. doi: 10.1016/j.dib.2018.04.086. eCollection 2018 Aug.

11.

Quantitative proteomic characterization and comparison of T helper 17 and induced regulatory T cells.

Mohammad I, Nousiainen K, Bhosale SD, Starskaia I, Moulder R, Rokka A, Cheng F, Mohanasundaram P, Eriksson JE, Goodlett DR, Lähdesmäki H, Chen Z.

PLoS Biol. 2018 May 31;16(5):e2004194. doi: 10.1371/journal.pbio.2004194. eCollection 2018 May.

12.

Correction to: Top Down Tandem Mass Spectrometric Analysis of a Chemically Modified Rough-Type Lipopolysaccharide Vaccine Candidate.

Oyler BL, Khan MM, Smith DF, Harberts EM, Kilgour DPA, Ernst RK, Cross AS, Goodlett DR.

J Am Soc Mass Spectrom. 2018 Jun;29(6):1230. doi: 10.1007/s13361-018-1960-8.

PMID:
29687418
13.

Quantitative targeted proteomic analysis of potential markers of tyrosine kinase inhibitor (TKI) sensitivity in EGFR mutated lung adenocarcinoma.

Awasthi S, Maity T, Oyler BL, Qi Y, Zhang X, Goodlett DR, Guha U.

J Proteomics. 2018 Oct 30;189:48-59. doi: 10.1016/j.jprot.2018.04.005. Epub 2018 Apr 13.

PMID:
29660496
14.

Host-pathogen dynamics through targeted secretome analysis of stimulated macrophages.

Khan MM, Koppenol-Raab M, Kuriakose M, Manes NP, Goodlett DR, Nita-Lazar A.

J Proteomics. 2018 Oct 30;189:34-38. doi: 10.1016/j.jprot.2018.03.016. Epub 2018 Mar 20.

PMID:
29572161
15.

Top Down Tandem Mass Spectrometric Analysis of a Chemically Modified Rough-Type Lipopolysaccharide Vaccine Candidate.

Oyler BL, Khan MM, Smith DF, Harberts EM, Kilgour DPA, Ernst RK, Cross AS, Goodlett DR.

J Am Soc Mass Spectrom. 2018 Jun;29(6):1221-1229. doi: 10.1007/s13361-018-1897-y. Epub 2018 Feb 20. Erratum in: J Am Soc Mass Spectrom. 2018 Apr 23;:.

PMID:
29464544
16.

Proteomics of Diabetes, Obesity, and Related Disorders.

Moulder R, Schvartz D, Goodlett DR, Dayon L.

Proteomics Clin Appl. 2018 Jan;12(1). doi: 10.1002/prca.201600134. No abstract available.

PMID:
29148229
17.

CXC Chemokines Exhibit Bactericidal Activity against Multidrug-Resistant Gram-Negative Pathogens.

Crawford MA, Fisher DJ, Leung LM, Lomonaco S, Lascols C, Cannatelli A, Giani T, Rossolini GM, Doi Y, Goodlett DR, Allard MW, Sharma SK, Khan E, Ernst RK, Hughes MA.

MBio. 2017 Nov 14;8(6). pii: e01549-17. doi: 10.1128/mBio.01549-17.

18.

Analysis of the plasma proteome using iTRAQ and TMT-based Isobaric labeling.

Moulder R, Bhosale SD, Goodlett DR, Lahesmaa R.

Mass Spectrom Rev. 2018 Sep;37(5):583-606. doi: 10.1002/mas.21550. Epub 2017 Nov 9. Review.

PMID:
29120501
19.

Structural modification of LPS in colistin-resistant, KPC-producing Klebsiella pneumoniae.

Leung LM, Cooper VS, Rasko DA, Guo Q, Pacey MP, McElheny CL, Mettus RT, Yoon SH, Goodlett DR, Ernst RK, Doi Y.

J Antimicrob Chemother. 2017 Nov 1;72(11):3035-3042. doi: 10.1093/jac/dkx234.

20.

Identification of the ESKAPE pathogens by mass spectrometric analysis of microbial membrane glycolipids.

Leung LM, Fondrie WE, Doi Y, Johnson JK, Strickland DK, Ernst RK, Goodlett DR.

Sci Rep. 2017 Jul 25;7(1):6403. doi: 10.1038/s41598-017-04793-4.

21.

Assessment of the Therapeutic Potential of Persimmon Leaf Extract on Prediabetic Subjects.

Khan MM, Tran BQ, Jang YJ, Park SH, Fondrie WE, Chowdhury K, Yoon SH, Goodlett DR, Chae SW, Chae HJ, Seo SY, Goo YA.

Mol Cells. 2017 Jul 31;40(7):466-475. doi: 10.14348/molcells.2017.2298. Epub 2017 Jul 6.

22.

Mass Spectrometry-Based Serum Proteomics for Biomarker Discovery and Validation.

Bhosale SD, Moulder R, Kouvonen P, Lahesmaa R, Goodlett DR.

Methods Mol Biol. 2017;1619:451-466. doi: 10.1007/978-1-4939-7057-5_31.

PMID:
28674903
23.

DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer.

Lund RJ, Huhtinen K, Salmi J, Rantala J, Nguyen EV, Moulder R, Goodlett DR, Lahesmaa R, Carpén O.

Sci Rep. 2017 May 4;7(1):1469. doi: 10.1038/s41598-017-01624-4.

24.

Hyper-phosphorylation of Sequestosome-1 Distinguishes Resistance to Cisplatin in Patient Derived High Grade Serous Ovarian Cancer Cells.

Nguyen EV, Huhtinen K, Goo YA, Kaipio K, Andersson N, Rantanen V, Hynninen J, Lahesmaa R, Carpen O, Goodlett DR.

Mol Cell Proteomics. 2017 Jul;16(7):1377-1392. doi: 10.1074/mcp.M116.058321. Epub 2017 Apr 28.

25.

Structural Modification of Lipopolysaccharide Conferred by mcr-1 in Gram-Negative ESKAPE Pathogens.

Liu YY, Chandler CE, Leung LM, McElheny CL, Mettus RT, Shanks RMQ, Liu JH, Goodlett DR, Ernst RK, Doi Y.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00580-17. doi: 10.1128/AAC.00580-17. Print 2017 Jun.

26.

Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship.

Scott AJ, Oyler BL, Goodlett DR, Ernst RK.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Nov;1862(11):1439-1450. doi: 10.1016/j.bbalip.2017.01.004. Epub 2017 Jan 17. Review.

27.

The progress and potential of proteomic biomarkers for type 1 diabetes in children.

Moulder R, Bhosale SD, Lahesmaa R, Goodlett DR.

Expert Rev Proteomics. 2017 Jan;14(1):31-41. doi: 10.1080/14789450.2017.1265449. Epub 2016 Dec 20. Review.

PMID:
27997253
28.

Global Analysis and Comparison of the Transcriptomes and Proteomes of Group A Streptococcus Biofilms.

Freiberg JA, Le Breton Y, Tran BQ, Scott AJ, Harro JM, Ernst RK, Goo YA, Mongodin EF, Goodlett DR, McIver KS, Shirtliff ME.

mSystems. 2016 Dec 6;1(6). pii: e00149-16. eCollection 2016 Nov-Dec.

29.

Autopiquer - a Robust and Reliable Peak Detection Algorithm for Mass Spectrometry.

Kilgour DPA, Hughes S, Kilgour SL, Mackay CL, Palmblad M, Tran BQ, Goo YA, Ernst RK, Clarke DJ, Goodlett DR.

J Am Soc Mass Spectrom. 2017 Feb;28(2):253-262. doi: 10.1007/s13361-016-1549-z. Epub 2016 Dec 6.

30.

A Deep Proteome Analysis Identifies the Complete Secretome as the Functional Unit of Human Cardiac Progenitor Cells.

Sharma S, Mishra R, Bigham GE, Wehman B, Khan MM, Xu H, Saha P, Goo YA, Datla SR, Chen L, Tulapurkar ME, Taylor BS, Yang P, Karathanasis S, Goodlett DR, Kaushal S.

Circ Res. 2017 Mar 3;120(5):816-834. doi: 10.1161/CIRCRESAHA.116.309782. Epub 2016 Dec 1.

31.

Secreted Effectors Encoded within and outside of the Francisella Pathogenicity Island Promote Intramacrophage Growth.

Eshraghi A, Kim J, Walls AC, Ledvina HE, Miller CN, Ramsey KM, Whitney JC, Radey MC, Peterson SB, Ruhland BR, Tran BQ, Goo YA, Goodlett DR, Dove SL, Celli J, Veesler D, Mougous JD.

Cell Host Microbe. 2016 Nov 9;20(5):573-583. doi: 10.1016/j.chom.2016.10.008.

32.

Detection of Carbofuran-Protein Adducts in Serum of Occupationally Exposed Pesticide Factory Workers in Pakistan.

Rehman T, Khan MM, Shad MA, Hussain M, Oyler BL, Goo YA, Goodlett DR.

Chem Res Toxicol. 2016 Oct 17;29(10):1720-1728. doi: 10.1021/acs.chemrestox.6b00222. Epub 2016 Oct 6.

PMID:
27657490
33.

Norharmane Matrix Enhances Detection of Endotoxin by MALDI-MS for Simultaneous Profiling of Pathogen, Host, and Vector Systems.

Scott AJ, Flinders B, Cappell J, Liang T, Pelc RS, Tran B, Kilgour DP, Heeren RM, Goodlett DR, Ernst RK.

Pathog Dis. 2016 Sep 19. pii: ftw097. [Epub ahead of print]

PMID:
27650574
34.

Rapid lipid a structure determination via surface acoustic wave nebulization and hierarchical tandem mass spectrometry algorithm.

Yoon SH, Liang T, Schneider T, Oyler BL, Chandler CE, Ernst RK, Yen GS, Huang Y, Nilsson E, Goodlett DR.

Rapid Commun Mass Spectrom. 2016 Dec 15;30(23):2555-2560. doi: 10.1002/rcm.7728.

PMID:
27582344
35.

Structural derivation of lipid A from Cronobacter sakazakii using tandem mass spectrometry.

Li Y, Yoon SH, Wang X, Ernst RK, Goodlett DR.

Rapid Commun Mass Spectrom. 2016 Oct 30;30(20):2265-70. doi: 10.1002/rcm.7712.

PMID:
27502448
36.

Normalization of NAD+ Redox Balance as a Therapy for Heart Failure.

Lee CF, Chavez JD, Garcia-Menendez L, Choi Y, Roe ND, Chiao YA, Edgar JS, Goo YA, Goodlett DR, Bruce JE, Tian R.

Circulation. 2016 Sep 20;134(12):883-94. doi: 10.1161/CIRCULATIONAHA.116.022495. Epub 2016 Aug 3.

37.

Strain competition restricts colonization of an enteric pathogen and prevents colitis.

Hecht AL, Casterline BW, Earley ZM, Goo YA, Goodlett DR, Bubeck Wardenburg J.

EMBO Rep. 2016 Sep;17(9):1281-91. doi: 10.15252/embr.201642282. Epub 2016 Jul 18.

38.

Surface acoustic wave nebulization device with dual interdigitated transducers improves SAWN-MS performance.

Huang Y, Heron SR, Clark AM, Edgar JS, Yoon SH, Kilgour DP, Turecek F, Aliseda A, Goodlett DR.

J Mass Spectrom. 2016 Jun;51(6):424-9. doi: 10.1002/jms.3766.

PMID:
27270865
39.

Use of captive spray ionization to increase throughput of the data-independent acquisition technique PAcIFIC.

Chapman JD, Edgar JS, Goodlett DR, Goo YA.

Rapid Commun Mass Spectrom. 2016 May 15;30(9):1101-7. doi: 10.1002/rcm.7544.

40.

Polydimethylsiloxane microchannel coupled to surface acoustic wave nebulization mass spectrometry.

Yen GS, Edgar JS, Yoon SH, Huang Y, Heron SR, Chiu DT, Goodlett DR.

Rapid Commun Mass Spectrom. 2016 Apr 30;30(8):1096-100. doi: 10.1002/rcm.7531. No abstract available.

PMID:
27003047
41.

Human symbionts inject and neutralize antibacterial toxins to persist in the gut.

Wexler AG, Bao Y, Whitney JC, Bobay LM, Xavier JB, Schofield WB, Barry NA, Russell AB, Tran BQ, Goo YA, Goodlett DR, Ochman H, Mougous JD, Goodman AL.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3639-44. doi: 10.1073/pnas.1525637113. Epub 2016 Mar 8.

42.

All-Trans-Retinoic Acid Enhances Mitochondrial Function in Models of Human Liver.

Tripathy S, Chapman JD, Han CY, Hogarth CA, Arnold SL, Onken J, Kent T, Goodlett DR, Isoherranen N.

Mol Pharmacol. 2016 May;89(5):560-74. doi: 10.1124/mol.116.103697. Epub 2016 Feb 26.

43.

Label-Free Quantitation for Clinical Proteomics.

Moulder R, Goo YA, Goodlett DR.

Methods Mol Biol. 2016;1410:65-76. doi: 10.1007/978-1-4939-3524-6_4.

PMID:
26867738
44.

Screen-printed digital microfluidics combined with surface acoustic wave nebulization for hydrogen-deuterium exchange measurements.

Monkkonen L, Edgar JS, Winters D, Heron SR, Mackay CL, Masselon CD, Stokes AA, Langridge-Smith PRR, Goodlett DR.

J Chromatogr A. 2016 Mar 25;1439:161-166. doi: 10.1016/j.chroma.2015.12.048. Epub 2015 Dec 21.

45.

Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry.

Tran BQ, Barton C, Feng J, Sandjong A, Yoon SH, Awasthi S, Liang T, Khan MM, Kilgour DP, Goodlett DR, Goo YA.

Data Brief. 2015 Nov 24;6:68-76. doi: 10.1016/j.dib.2015.11.031. eCollection 2016 Mar.

46.

An ambient detection system for visualization of charged particles generated with ionization methods at atmospheric pressure.

Hommersom B, Syed SU, Eijkel GB, Kilgour DP, Goodlett DR, Heeren RM.

Rapid Commun Mass Spectrom. 2016 Feb 15;30(3):352-8. doi: 10.1002/rcm.7442.

PMID:
26754127
47.

Comprehensive glycosylation profiling of IgG and IgG-fusion proteins by top-down MS with multiple fragmentation techniques.

Tran BQ, Barton C, Feng J, Sandjong A, Yoon SH, Awasthi S, Liang T, Khan MM, Kilgour DPA, Goodlett DR, Goo YA.

J Proteomics. 2016 Feb 16;134:93-101. doi: 10.1016/j.jprot.2015.10.021. Epub 2015 Oct 17.

PMID:
26485299
48.

An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.

Whitney JC, Quentin D, Sawai S, LeRoux M, Harding BN, Ledvina HE, Tran BQ, Robinson H, Goo YA, Goodlett DR, Raunser S, Mougous JD.

Cell. 2015 Oct 22;163(3):607-19. doi: 10.1016/j.cell.2015.09.027. Epub 2015 Oct 8.

49.

Site-specific activity of the acyltransferases HtrB1 and HtrB2 in Pseudomonas aeruginosa lipid A biosynthesis.

Hittle LE, Powell DA, Jones JW, Tofigh M, Goodlett DR, Moskowitz SM, Ernst RK.

Pathog Dis. 2015 Nov;73(8):ftv053. doi: 10.1093/femspd/ftv053. Epub 2015 Jul 29.

50.

Advances in protein complex analysis by chemical cross-linking coupled with mass spectrometry (CXMS) and bioinformatics.

Tran BQ, Goodlett DR, Goo YA.

Biochim Biophys Acta. 2016 Jan;1864(1):123-9. doi: 10.1016/j.bbapap.2015.05.015. Epub 2015 May 27. Review.

PMID:
26025770

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