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Items: 18


Regulation of histone methylation by automethylation of PRC2.

Wang X, Long Y, Paucek RD, Gooding AR, Lee T, Burdorf RM, Cech TR.

Genes Dev. 2019 Oct 1;33(19-20):1416-1427. doi: 10.1101/gad.328849.119. Epub 2019 Sep 5.


Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2.

Long Y, Bolanos B, Gong L, Liu W, Goodrich KJ, Yang X, Chen S, Gooding AR, Maegley KA, Gajiwala KS, Brooun A, Cech TR, Liu X.

Elife. 2017 Nov 29;6. pii: e31558. doi: 10.7554/eLife.31558.


Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.

Wang X, Paucek RD, Gooding AR, Brown ZZ, Ge EJ, Muir TW, Cech TR.

Nat Struct Mol Biol. 2017 Dec;24(12):1028-1038. doi: 10.1038/nsmb.3487. Epub 2017 Oct 23.


Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines.

Wang X, Goodrich KJ, Gooding AR, Naeem H, Archer S, Paucek RD, Youmans DT, Cech TR, Davidovich C.

Mol Cell. 2017 Mar 16;65(6):1056-1067.e5. doi: 10.1016/j.molcel.2017.02.003.


RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure.

Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY.

Cell. 2016 May 19;165(5):1267-1279. doi: 10.1016/j.cell.2016.04.028. Epub 2016 May 12.


Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA.

Davidovich C, Wang X, Cifuentes-Rojas C, Goodrich KJ, Gooding AR, Lee JT, Cech TR.

Mol Cell. 2015 Feb 5;57(3):552-8. doi: 10.1016/j.molcel.2014.12.017. Epub 2015 Jan 15.


A dimeric state for PRC2.

Davidovich C, Goodrich KJ, Gooding AR, Cech TR.

Nucleic Acids Res. 2014 Aug;42(14):9236-48. doi: 10.1093/nar/gku540. Epub 2014 Jul 3.


Preparation of group I introns for biochemical studies and crystallization assays by native affinity purification.

Vicens Q, Gooding AR, Duarte LF, Batey RT.

PLoS One. 2009 Aug 27;4(8):e6740. doi: 10.1371/journal.pone.0006740.


The Cech Symposium: a celebration of 25 years of ribozymes, 10 years of TERT, and 60 years of Tom.

Vicens Q, Allen MA, Gilbert SD, Reznik B, Gooding AR, Batey RT.

RNA. 2008 Mar;14(3):397-403. doi: 10.1261/rna.910008. Epub 2008 Jan 18.


Local RNA structural changes induced by crystallization are revealed by SHAPE.

Vicens Q, Gooding AR, Laederach A, Cech TR.

RNA. 2007 Apr;13(4):536-48. Epub 2007 Feb 13.


A preorganized active site in the crystal structure of the Tetrahymena ribozyme.

Golden BL, Gooding AR, Podell ER, Cech TR.

Science. 1998 Oct 9;282(5387):259-64.


Crystals by design: a strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron.

Golden BL, Podell ER, Gooding AR, Cech TR.

J Mol Biol. 1997 Aug 1;270(5):711-23.


X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering.

Golden BL, Gooding AR, Podell ER, Cech TR.

RNA. 1996 Dec;2(12):1295-305.


RNA tertiary structure mediation by adenosine platforms.

Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Szewczak AA, Kundrot CE, Cech TR, Doudna JA.

Science. 1996 Sep 20;273(5282):1696-9.


Crystal structure of a group I ribozyme domain: principles of RNA packing.

Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Kundrot CE, Cech TR, Doudna JA.

Science. 1996 Sep 20;273(5282):1678-85.


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